Gene Symbol | polh-1 |
Entrez Gene ID | 175337 |
Full Name | POLH (DNA polymerase eta) homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » polh-1 cDNA ORF clone
Gene Symbol | polh-1 |
Entrez Gene ID | 175337 |
Full Name | POLH (DNA polymerase eta) homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_065079.3 | NP_497480.2 | UmuC domain-containing protein |
NM_065079.2 | NP_497480.2 | POLH (DNA polymerase eta) homolog |
Homo sapiens (human) | POLH | NP_006493.1 |
POLH | XP_002803805.1 | |
Canis lupus familiaris (dog) | POLH | XP_532150.2 |
Rattus norvegicus (Norway rat) | Polh | NP_001101674.1 |
Danio rerio (zebrafish) | polh | NP_001035337.1 |
Xenopus tropicalis (tropical clawed frog) | polh | XP_002942198.2 |
Mus musculus (house mouse) | Polh | NP_109640.1 |
Bos taurus (cattle) | POLH | NP_001029622.1 |
Gallus gallus (chicken) | POLH | NP_001001304.1 |
Pan troglodytes (chimpanzee) | POLH | XP_518497.1 |
Caenorhabditis elegans (roundworm) | polh-1 | NP_497480.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SUMO-mediated regulation of both POLH-1 and POLK-1, and point towards a previously unrecognized role of the nuclear pore in regulating Translesion synthesis .
Title: A broad requirement for TLS polymerases ? and ?, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis.
These studies reveal that POLH-1 undergoes DNA-damage-induced proteolysis and that GEI-17 regulates the timing of this proteolysis.
Title: Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans.
findings indicate that Poleta contributes significantly to damage tolerance in early embryogenesis but only modestly at later stages; may confer UV resistance perhaps by catalyzing translesion synthesis in early embryogenesis
Title: Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development.
The following polh-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the polh-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340807 | |
Clone ID Related Accession (Same CDS sequence) | NM_065079.3 , NM_065079.2 | |
Accession Version | NM_065079.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | UmuC domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_065079.2. |
1 | ATGAAAAGAG TGATCAGCCT CATCGATATG GACTGTTTCT ACGCACAAGT CGAACAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497480.2 |
CDS | 18..1772 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065079.3 |
1 | ATGAAAAGAG TGATCAGCCT CATCGATATG GACTGTTTCT ACGCACAAGT CGAACAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340807 | |
Clone ID Related Accession (Same CDS sequence) | NM_065079.3 , NM_065079.2 | |
Accession Version | NM_065079.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | POLH (DNA polymerase eta) homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Oct 5, 2006 this sequence version replaced NM_065079.1. COMPLETENESS: incomplete on both ends. |
1 | ATGAAAAGAG TGATCAGCCT CATCGATATG GACTGTTTCT ACGCACAAGT CGAACAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497480.2 |
CDS | 1..1755 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065079.2 |
1 | ATGAAAAGAG TGATCAGCCT CATCGATATG GACTGTTTCT ACGCACAAGT CGAACAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |