Gene Symbol | dcr1 |
Entrez Gene ID | 2538930 |
Full Name | dicer |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » dcr1 cDNA ORF clone
Gene Symbol | dcr1 |
Entrez Gene ID | 2538930 |
Full Name | dicer |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001023205.2 | NP_588215.2 | dicer |
Homo sapiens (human) | DICER1 | NP_085124.2 |
Rattus norvegicus (Norway rat) | Dicer1 | XP_006240573.1 |
Danio rerio (zebrafish) | dicer1 | NP_001154925.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002836 | XP_003436256.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01541 | XP_003714515.1 |
Neurospora crassa | NCU08270 | XP_961898.1 |
DICER1 | XP_001100868.1 | |
Gallus gallus (chicken) | DICER1 | NP_001035555.1 |
Drosophila melanogaster (fruit fly) | Dcr-1 | NP_524453.1 |
Caenorhabditis elegans (roundworm) | dcr-1 | NP_498761.2 |
Xenopus tropicalis (tropical clawed frog) | dicer1 | NP_001123390.2 |
Canis lupus familiaris (dog) | DICER1 | XP_868526.3 |
Bos taurus (cattle) | DICER1 | NP_976235.1 |
Schizosaccharomyces pombe (fission yeast) | dcr1 | NP_588215.2 |
Pan troglodytes (chimpanzee) | DICER1 | XP_001154369.1 |
Mus musculus (house mouse) | Dicer1 | NP_683750.2 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Findings suggest that in S. pombe Dcr1 has a genome-wide role in terminating transcription by releasing Pol II at sites of collision between transcription and replication and thus maintains genome stability.
Title: Dicer promotes transcription termination at sites of replication stress to maintain genome stability.
Studies indicate that S. pombe genome encodes one of each of the core RNAi proteins, Dicer, Argonaute and RNA-dependent RNA polymerase (dcr1, ago1, rdp1).
Title: RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe.
Data indicate that Argonaute, loaded with longer RNA precursors, recruits Triman (SPBC29A10.09c, 3'-5' Exonuclease) to generate dicer-independent priRNAs mature priRNAs and siRNAs.
Title: Argonaute and Triman generate dicer-independent priRNAs and mature siRNAs to initiate heterochromatin formation.
these results reveal novel insights into the mechanism of nuclear retention of Dcr1 and raise the possibility that this new class of dsRBDs might generally function in nucleocytoplasmic trafficking and not substrate binding
Title: An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer.
Dcr1 has a role in post-transcriptional regulation of gene expression in Schizosaccharomyces pombe [review]
Title: Involvement of Dcr1 in post-transcriptional regulation of gene expression in Schizosaccharomyces pombe.
The following dcr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dcr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc99079 | |
Clone ID Related Accession (Same CDS sequence) | NM_001023205.2 | |
Accession Version | NM_001023205.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4125bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | dicer | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). On Dec 10, 2012 this sequence version replaced NM_001023205.1. |
1 | ATGGATATTT CAAGTTTTCT ACTTCCTCAA CTTTTACGTA AATATCAACA AGATGTGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_588215.2 |
CDS | 285..4409 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGATATTT CAAGTTTTCT ACTTCCTCAA CTTTTACGTA AATATCAACA AGATGTGTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |