Gene Symbol | upf1 |
Entrez Gene ID | 2542327 |
Full Name | ATP-dependent RNA helicase Upf1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » upf1 cDNA ORF clone
Gene Symbol | upf1 |
Entrez Gene ID | 2542327 |
Full Name | ATP-dependent RNA helicase Upf1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001018477.2 | NP_593080.1 | ATP-dependent RNA helicase Upf1 |
Pan troglodytes (chimpanzee) | UPF1 | XP_512972.4 |
Mus musculus (house mouse) | Upf1 | NP_001116301.1 |
Eremothecium gossypii | AGOS_ABR022C | NP_982968.4 |
LOC720288 | XP_002808229.1 | |
Canis lupus familiaris (dog) | UPF1 | XP_005632737.1 |
Bos taurus (cattle) | UPF1 | XP_005208537.1 |
Saccharomyces cerevisiae (baker's yeast) | NAM7 | NP_013797.1 |
Schizosaccharomyces pombe (fission yeast) | upf1 | NP_593080.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00976 | XP_003717973.1 |
Gallus gallus (chicken) | UPF1 | XP_418237.3 |
Danio rerio (zebrafish) | upf1 | NP_998639.1 |
Drosophila melanogaster (fruit fly) | Upf1 | NP_572767.1 |
Oryza sativa (rice) | Os07g0495900 | NP_001059698.1 |
Homo sapiens (human) | UPF1 | NP_002902.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001133 | XP_322028.4 |
Caenorhabditis elegans (roundworm) | smg-2 | NP_490829.1 |
Kluyveromyces lactis | KLLA0B06435g | XP_451821.1 |
Neurospora crassa | NCU04242 | XP_961233.1 |
Rattus norvegicus (Norway rat) | Upf1 | XP_003751614.1 |
Arabidopsis thaliana (thale cress) | LBA1 | NP_199512.2 |
Xenopus tropicalis (tropical clawed frog) | upf1 | XP_002938872.2 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
study defined a population of mRNAs specifically regulated by Upf1; showed Upf2 and Upf3 are required for binding of Upf1 to its RNA targets and for proper response to oxidative stress; demonstrated that Upf1-dependent downregulation of some of its direct targets is necessary for resistance to oxidative stress
Title: Functional characterization of Upf1 targets in Schizosaccharomyces pombe.
upf1Delta and csx1Delta strains are similarly sensitive to oxidative stress, and the effects of the mutations are not additive, suggesting that Upf1 and Csx1 work in the same pathway to stabilize atf1(+) mRNA during oxidative stress.
Title: Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast.
The following upf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the upf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc101771 | |
Clone ID Related Accession (Same CDS sequence) | NM_001018477.2 | |
Accession Version | NM_001018477.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2778bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | ATP-dependent RNA helicase Upf1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced NM_001018477.1. |
1 | ATGTCTTTAG GGCTACAACC TAATAATGAT ATTTCATCTT TAGTTAGTTC AAAAAATATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_593080.1 |
CDS | 37..2814 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001018477.2 |
1 | ATGTCTTTAG GGCTACAACC TAATAATGAT ATTTCATCTT TAGTTAGTTC AAAAAATATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |