Gene Symbol | CDC13 |
Entrez Gene ID | 851306 |
Full Name | telomere-binding protein CDC13 |
Synonyms | EST4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC13 cDNA ORF clone
Gene Symbol | CDC13 |
Entrez Gene ID | 851306 |
Full Name | telomere-binding protein CDC13 |
Synonyms | EST4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180280.1 | NP_010061.1 | telomere-binding protein CDC13 |
Kluyveromyces lactis | KLLA0F20922g | XP_456019.1 |
Saccharomyces cerevisiae (baker's yeast) | CDC13 | NP_010061.1 |
Eremothecium gossypii | AGOS_ABL155C | NP_982792.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that by controlling the timing of Cdc13 and Stn1 phosphorylations, Cdk1 regulates the temporal recruitment of telomerase complexes and Cdc13-Stn1-Ten1 (CST) complexes to the telomeres to facilitate telomere maintenance.
Title: Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication.
The core Cdc13 ssDNA-binding activity is wholly contained within a single tight-binding oligosaccharide/oligonucleotide/oligopeptide binding (OB)-fold.
Title: The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain.
regulated binding of Cdc13 to chromosome termini dictates subsequent interaction of a recruitment-competent telomerase complex with telomeres
Title: A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle.
Dimerization of the OB2 domain of Cdc13 is required for proper Cdc13, Stn1, Ten1 (CST) assembly and productive telomere capping.
Title: Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance.
Cdc13, and a S314D mutation negatively affected telomere length. Our findings provide new targets in Cdc13 - a key telomerase regulatory protein for modulation of telomere dynamics
Title: Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation.
The following CDC13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00870 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180280.1 | |
Accession Version | NM_001180280.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2775bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | telomere-binding protein CDC13 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATACCT TAGAAGAGCC TGAGTGTCCT CCACATAAAA ATCGTATTTT TGTGAGCTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010061.1 |
CDS | 1..2775 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180280.1 |
1 | ATGGATACCT TAGAAGAGCC TGAGTGTCCT CCACATAAAA ATCGTATTTT TGTGAGCTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |