Masp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Masp1
Entrez Gene ID	64023
Full Name	mannan-binding lectin serine peptidase 1
Synonyms	Masp1/3,Masp3
General protein information	Preferred Names mannan-binding lectin serine peptidase 1 Names mannan-binding lectin serine protease 1 MASP-1 complement factor MASP-3 complement-activating component of Ra-reactive factor mannan-binding lectin serine protease 2-like mannose-binding lectin-associated serine protease 1 mannose-binding protein associated serine protease-1 mannose-binding protein-associated serine protease ra-reactive factor serine protease p100 raRF serine protease 5 serine protease MASP1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q23
Summary	serine protease that plays a role in the mannan-binding lectin complement pathway [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006248526.3	XP_006248588.1	mannan-binding lectin serine protease 1 isoform X1
XM_008768804.2	XP_008767026.1	mannan-binding lectin serine protease 1 isoform X2
NM_022257.1	NP_071593.1	mannan-binding lectin serine protease 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Masp1	NP_032581.2
Pan troglodytes (chimpanzee)	MASP1	XP_516941.3
Rattus norvegicus (Norway rat)	Masp1	NP_071593.1

Gene Ontology
Bibliography

Related articles in PubMed

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Nan R, Furze CM, Wright DW, Gor J, Wallis R, Perkins SJ
Structure (London, England : 1993)25(2)364-375(2017 02)

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation.
Gingras AR, Girija UV, Keeble AH, Panchal R, Mitchell DA, Moody PC, Wallis R
Structure (London, England : 1993)19(11)1635-43(2011 Nov)

Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins.
Teillet F, Gaboriaud C, Lacroix M, Martin L, Arlaud GJ, Thielens NM
The Journal of biological chemistry283(37)25715-24(2008 Sep)

Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.
Takahashi M, Iwaki D, Kanno K, Ishida Y, Xiong J, Matsushita M, Endo Y, Miura S, Ishii N, Sugamura K, Fujita T
Journal of immunology (Baltimore, Md. : 1950)180(9)6132-8(2008 May)

Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.
M?ller-Kristensen M, Thiel S, Sj?holm A, Matsushita M, Jensenius JC
International immunology19(2)141-9(2007 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Flexibility in MASP-1 and MASP-2 provides insight on lectin pathway activation.
Title: Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.

we present the first structure of such a complex in the form of the collagen-like domain of mannan-binding lectin and the binding domain of its associated protease MASP-1
Title: Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation.

MASP-1 probably enhances complement activation triggered by MBP.MASP-2 complexes, but it cannot initiate activation itself
Title: Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases.

The following Masp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Masp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa43548	XM_008768804.2 Latest version!	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05560	NM_022257.1 Latest version!	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$412.30 $589.00
ORa34388	XM_006248526.3 Latest version!	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Masp1 ( XM_008768804.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008767026.1 Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa43548
Clone ID Related Accession (Same CDS sequence)	XM_008768804.2
Accession Version	XM_008768804.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mannan-binding lectin serine protease 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768804.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGGGG 
TTCCGGGTCC AGCTTTACTT CATGCACTTC AACTTGGAAT CCTCCTACCT TTGTGAATAT 
GACTATGTGA AGGTAGAAAC CGAAGACCAG GTGCTGGCAA CCTTCTGTGG CAGGGAGACC 
ACCGATACCG AGCAGACCCC GGGCCAGGAA GTGGTTCTTT CGCCTGGTTC CTTTATGTCT 
GTCACTTTCC GGTCAGATTT CTCCAATGAG GAACGATTCA CAGGTTTTGA CGCCCACTAC 
ATGGCTGTAG ATGTGGATGA GTGCAAGGAA AGGGAAGATG AGGAGCTGTC CTGTGACCAC 
TACTGCCACA ACTACATCGG CGGCTACTAC TGCTCCTGTC GCTTTGGCTA CATCCTCCAC 
ACAGACAACA GGACCTGCCG AGTGGAATGC AGTGGCAATC TCTTTACCCA GAGGACAGGC 
ACAATCACCA GCCCGGATTA CCCCAACCCT TACCCCAAGA GCTCTGAATG TTCCTATACC 
ATTGACCTGG AGGAGGGCTT CATGGTTACC CTGCAGTTTG AGGACATTTT TGACATTGAA 
GACCATCCCG AGGTGCCCTG TCCCTATGAC TACATTAAGA TTAAAGCTGG TTCAAAAGTA 
TGGGGACCCT TCTGTGGAGA GAAATCCCCA GAACCAATCA GCACCCAGAG TCATAGCATC 
CAGATCCTAT TTCGCAGCGA CAATTCAGGA GAGAACCGAG GCTGGAGGCT CTCCTACAGG 
GCTGCAGGAA ATGAGTGCCC AAAGCTACAA CCCCCCGTGT ATGGGAAAAT TGAACCCTCG 
CAAGCCGTGT ACTCCTTCAA AGACCAAGTG CTCATCAGCT GTGACACGGG CTACAAAGTG 
CTAAAGGATA ACGAGGTGAT GGACACATTC CAAATTGAGT GTCTGAAGGA TGGTGCATGG 
AGTAACAAGA TTCCCACCTG TAAAAAAAGC GAGATCGATT TGGAGGAGGA GCTGGAGTCA 
GAGCAAGTGG CAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008767026.1
CDS	337..1494
Translation	MRFLSFRRLLLYHVLCLTLTEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEGFRVQLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVTLQFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQSHSIQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLISCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKKSEIDLEEELESEQVAE

Target ORF information:

RefSeq Version	XM_008768804.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768804.2

ORF Insert Sequence:

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGGGG 
TTCCGGGTCC AGCTTTACTT CATGCACTTC AACTTGGAAT CCTCCTACCT TTGTGAATAT 
GACTATGTGA AGGTAGAAAC CGAAGACCAG GTGCTGGCAA CCTTCTGTGG CAGGGAGACC 
ACCGATACCG AGCAGACCCC GGGCCAGGAA GTGGTTCTTT CGCCTGGTTC CTTTATGTCT 
GTCACTTTCC GGTCAGATTT CTCCAATGAG GAACGATTCA CAGGTTTTGA CGCCCACTAC 
ATGGCTGTAG ATGTGGATGA GTGCAAGGAA AGGGAAGATG AGGAGCTGTC CTGTGACCAC 
TACTGCCACA ACTACATCGG CGGCTACTAC TGCTCCTGTC GCTTTGGCTA CATCCTCCAC 
ACAGACAACA GGACCTGCCG AGTGGAATGC AGTGGCAATC TCTTTACCCA GAGGACAGGC 
ACAATCACCA GCCCGGATTA CCCCAACCCT TACCCCAAGA GCTCTGAATG TTCCTATACC 
ATTGACCTGG AGGAGGGCTT CATGGTTACC CTGCAGTTTG AGGACATTTT TGACATTGAA 
GACCATCCCG AGGTGCCCTG TCCCTATGAC TACATTAAGA TTAAAGCTGG TTCAAAAGTA 
TGGGGACCCT TCTGTGGAGA GAAATCCCCA GAACCAATCA GCACCCAGAG TCATAGCATC 
CAGATCCTAT TTCGCAGCGA CAATTCAGGA GAGAACCGAG GCTGGAGGCT CTCCTACAGG 
GCTGCAGGAA ATGAGTGCCC AAAGCTACAA CCCCCCGTGT ATGGGAAAAT TGAACCCTCG 
CAAGCCGTGT ACTCCTTCAA AGACCAAGTG CTCATCAGCT GTGACACGGG CTACAAAGTG 
CTAAAGGATA ACGAGGTGAT GGACACATTC CAAATTGAGT GTCTGAAGGA TGGTGCATGG 
AGTAACAAGA TTCCCACCTG TAAAAAAAGC GAGATCGATT TGGAGGAGGA GCTGGAGTCA 
GAGCAAGTGG CAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Masp1 ( NM_022257.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071593.1 Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), mRNA.

Price & Availability↑

CloneID	ORa05560
Clone ID Related Accession (Same CDS sequence)	NM_022257.1
Accession Version	NM_022257.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	mannan-binding lectin serine protease 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ457084.1. On Apr 2, 2004 this sequence version replaced XM_213605.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ457084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGTTC 
CGGGTCCAGC TTTACTTCAT GCACTTCAAC TTGGAATCCT CCTACCTTTG TGAATATGAC 
TATGTGAAGG TAGAAACCGA AGACCAGGTG CTGGCAACCT TCTGTGGCAG GGAGACCACC 
GATACCGAGC AGACCCCGGG CCAGGAAGTG GTTCTTTCGC CTGGTTCCTT TATGTCTGTC 
ACTTTCCGGT CAGATTTCTC CAATGAGGAA CGATTCACAG GTTTTGACGC CCACTACATG 
GCTGTAGATG TGGATGAGTG CAAGGAAAGG GAAGATGAGG AGCTGTCCTG TGACCACTAC 
TGCCACAACT ACATCGGCGG CTACTACTGC TCCTGTCGCT TTGGCTACAT CCTCCACACA 
GACAACAGGA CCTGCCGAGT GGAATGCAGT GGCAATCTCT TTACCCAGAG GACAGGCACA 
ATCACCAGCC CGGATTACCC CAACCCTTAC CCCAAGAGCT CTGAATGTTC CTATACCATT 
GACCTGGAGG AGGGCTTCAT GGTTACCCTG CACTTTGAGG ACATTTTTGA CATTGAAGAC 
CATCCCGAGG TGCCCTGTCC CTATGACTAC ATTAAGATTA AAGCTGGTTC AAAAGTATGG 
GGACCCTTCT GTGGAGAGAA ATCCCCAGAA CCAATCAGCA CCCAGAGTCA TAGCATCCAG 
ATCCTATTTC GCAGCGACAA TTCAGGAGAG AACCGAGGCT GGAGGCTCTC CTACAGGGCT 
GCAGGAAATG AGTGCCCAAA GCTACAACCC CCCGTGTATG GGAAAATTGA ACCCTCGCAA 
GCCGTGTACT CCTTCAAAGA CCAAGTGCTC ATCAGCTGTG ACACGGGCTA CAAAGTGCTA 
AAGGATAACG AGGTGATGGA CACATTCCAA ATTGAGTGTC TGAAGGATGG TGCATGGAGT 
AACAAGATTC CCACCTGTAA AATTGTAGAC TGTGGAGTTC CAGCAGTGCT GAAACATGGG 
CTAGTAACCT TCTCCACAAG AAACAACCTC ACCACGTACA AATCTGAGAT AAGGTACTCC 
TGCCAGCAAC CCTATTACAA GATGCTTCAC AATACCACAG GTGTATATAC ATGTTCTGCT 
CATGGGACCT GGACAAATGA AGTGCTCAAG AGAAGCCTGC CCACCTGCCT TCCAGTGTGT 
GGTCTCCCCA AGTTCTCCCG GAAGCACATC TCCAGGATCT TCAATGGACG CCCAGCCCAG 
AAGGGTACCA CTCCATGGAT TGCCATGCTG TCACAACTGA ATGGGCAACC CTTCTGTGGG 
GGTAGCCTTT TAGGTTCCAA CTGGGTTTTG ACGGCTGCTC ACTGTCTCCA CCATCCACTT 
GATCCAGAAG AGCCAATCTT ACACAACTCA CATTTGCTCA GCCCTTCTGA CTTCAAAATT 
ATCATGGGAA AGCACTGGAG ACGCCGCTCA GATGAAGACG AACAGCATCT GCATGTAAAG 
CACATCATGC TCCACCCGCT GTACAACCCC AGCACATTTG AGAACGACTT GGGTCTGGTG 
GAACTGTCAG AGAGTCCAAG GCTGAACGAC TTTGTGATGC CTGTCTGTCT GCCTGAGCAC 
CCTTCCACTG AAGGAACCAT GGTCATCGTC AGCGGCTGGG GGAAGCAGTT CCTACAGAGG 
CTTCCAGAGA ACCTGATGGA GATTGAAATC CCAATTGTAA ACTACCATAC CTGCCAAGAG 
GCCTACACCC CATTGGGGAA GAAAGTGACC CAGGACATGA TCTGTGCTGG AGAAAAGGAA 
GGGGGAAAAG ACGCCTGTGC TGGCGACTCT GGAGGCCCCA TGGTGACCAA AGATGCAGAG 
AGAGACCAAT GGTACCTGGT GGGCGTGGTG TCCTGGGGTG AAGATTGCGG GAAGAAAGAT 
CGCTATGGAG TTTATTCTTA TATCTATCCC AACAAGGATT GGATCCAGAG GGTCACTGGG 
GTGAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071593.1
CDS	101..2212
Translation	MRFLSFRRLLLYHVLCLTLTEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEFRVQLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVTLHFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQSHSIQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLISCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKIVDCGVPAVLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGLPKFSRKHISRIFNGRPAQKGTTPWIAMLSQLNGQPFCGGSLLGSNWVLTAAHCLHHPLDPEEPILHNSHLLSPSDFKIIMGKHWRRRSDEDEQHLHVKHIMLHPLYNPSTFENDLGLVELSESPRLNDFVMPVCLPEHPSTEGTMVIVSGWGKQFLQRLPENLMEIEIPIVNYHTCQEAYTPLGKKVTQDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWIQRVTGVRN

Target ORF information:

RefSeq Version	NM_022257.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022257.1

ORF Insert Sequence:

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGTTC 
CGGGTCCAGC TTTACTTCAT GCACTTCAAC TTGGAATCCT CCTACCTTTG TGAATATGAC 
TATGTGAAGG TAGAAACCGA AGACCAGGTG CTGGCAACCT TCTGTGGCAG GGAGACCACC 
GATACCGAGC AGACCCCGGG CCAGGAAGTG GTTCTTTCGC CTGGTTCCTT TATGTCTGTC 
ACTTTCCGGT CAGATTTCTC CAATGAGGAA CGATTCACAG GTTTTGACGC CCACTACATG 
GCTGTAGATG TGGATGAGTG CAAGGAAAGG GAAGATGAGG AGCTGTCCTG TGACCACTAC 
TGCCACAACT ACATCGGCGG CTACTACTGC TCCTGTCGCT TTGGCTACAT CCTCCACACA 
GACAACAGGA CCTGCCGAGT GGAATGCAGT GGCAATCTCT TTACCCAGAG GACAGGCACA 
ATCACCAGCC CGGATTACCC CAACCCTTAC CCCAAGAGCT CTGAATGTTC CTATACCATT 
GACCTGGAGG AGGGCTTCAT GGTTACCCTG CACTTTGAGG ACATTTTTGA CATTGAAGAC 
CATCCCGAGG TGCCCTGTCC CTATGACTAC ATTAAGATTA AAGCTGGTTC AAAAGTATGG 
GGACCCTTCT GTGGAGAGAA ATCCCCAGAA CCAATCAGCA CCCAGAGTCA TAGCATCCAG 
ATCCTATTTC GCAGCGACAA TTCAGGAGAG AACCGAGGCT GGAGGCTCTC CTACAGGGCT 
GCAGGAAATG AGTGCCCAAA GCTACAACCC CCCGTGTATG GGAAAATTGA ACCCTCGCAA 
GCCGTGTACT CCTTCAAAGA CCAAGTGCTC ATCAGCTGTG ACACGGGCTA CAAAGTGCTA 
AAGGATAACG AGGTGATGGA CACATTCCAA ATTGAGTGTC TGAAGGATGG TGCATGGAGT 
AACAAGATTC CCACCTGTAA AATTGTAGAC TGTGGAGTTC CAGCAGTGCT GAAACATGGG 
CTAGTAACCT TCTCCACAAG AAACAACCTC ACCACGTACA AATCTGAGAT AAGGTACTCC 
TGCCAGCAAC CCTATTACAA GATGCTTCAC AATACCACAG GTGTATATAC ATGTTCTGCT 
CATGGGACCT GGACAAATGA AGTGCTCAAG AGAAGCCTGC CCACCTGCCT TCCAGTGTGT 
GGTCTCCCCA AGTTCTCCCG GAAGCACATC TCCAGGATCT TCAATGGACG CCCAGCCCAG 
AAGGGTACCA CTCCATGGAT TGCCATGCTG TCACAACTGA ATGGGCAACC CTTCTGTGGG 
GGTAGCCTTT TAGGTTCCAA CTGGGTTTTG ACGGCTGCTC ACTGTCTCCA CCATCCACTT 
GATCCAGAAG AGCCAATCTT ACACAACTCA CATTTGCTCA GCCCTTCTGA CTTCAAAATT 
ATCATGGGAA AGCACTGGAG ACGCCGCTCA GATGAAGACG AACAGCATCT GCATGTAAAG 
CACATCATGC TCCACCCGCT GTACAACCCC AGCACATTTG AGAACGACTT GGGTCTGGTG 
GAACTGTCAG AGAGTCCAAG GCTGAACGAC TTTGTGATGC CTGTCTGTCT GCCTGAGCAC 
CCTTCCACTG AAGGAACCAT GGTCATCGTC AGCGGCTGGG GGAAGCAGTT CCTACAGAGG 
CTTCCAGAGA ACCTGATGGA GATTGAAATC CCAATTGTAA ACTACCATAC CTGCCAAGAG 
GCCTACACCC CATTGGGGAA GAAAGTGACC CAGGACATGA TCTGTGCTGG AGAAAAGGAA 
GGGGGAAAAG ACGCCTGTGC TGGCGACTCT GGAGGCCCCA TGGTGACCAA AGATGCAGAG 
AGAGACCAAT GGTACCTGGT GGGCGTGGTG TCCTGGGGTG AAGATTGCGG GAAGAAAGAT 
CGCTATGGAG TTTATTCTTA TATCTATCCC AACAAGGATT GGATCCAGAG GGTCACTGGG 
GTGAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Masp1 ( XM_006248526.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248588.1 Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34388
Clone ID Related Accession (Same CDS sequence)	XM_006248526.3
Accession Version	XM_006248526.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mannan-binding lectin serine protease 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248526.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGGGG 
TTCCGGGTCC AGCTTTACTT CATGCACTTC AACTTGGAAT CCTCCTACCT TTGTGAATAT 
GACTATGTGA AGGTAGAAAC CGAAGACCAG GTGCTGGCAA CCTTCTGTGG CAGGGAGACC 
ACCGATACCG AGCAGACCCC GGGCCAGGAA GTGGTTCTTT CGCCTGGTTC CTTTATGTCT 
GTCACTTTCC GGTCAGATTT CTCCAATGAG GAACGATTCA CAGGTTTTGA CGCCCACTAC 
ATGGCTGTAG ATGTGGATGA GTGCAAGGAA AGGGAAGATG AGGAGCTGTC CTGTGACCAC 
TACTGCCACA ACTACATCGG CGGCTACTAC TGCTCCTGTC GCTTTGGCTA CATCCTCCAC 
ACAGACAACA GGACCTGCCG AGTGGAATGC AGTGGCAATC TCTTTACCCA GAGGACAGGC 
ACAATCACCA GCCCGGATTA CCCCAACCCT TACCCCAAGA GCTCTGAATG TTCCTATACC 
ATTGACCTGG AGGAGGGCTT CATGGTTACC CTGCAGTTTG AGGACATTTT TGACATTGAA 
GACCATCCCG AGGTGCCCTG TCCCTATGAC TACATTAAGA TTAAAGCTGG TTCAAAAGTA 
TGGGGACCCT TCTGTGGAGA GAAATCCCCA GAACCAATCA GCACCCAGAG TCATAGCATC 
CAGATCCTAT TTCGCAGCGA CAATTCAGGA GAGAACCGAG GCTGGAGGCT CTCCTACAGG 
GCTGCAGGAA ATGAGTGCCC AAAGCTACAA CCCCCCGTGT ATGGGAAAAT TGAACCCTCG 
CAAGCCGTGT ACTCCTTCAA AGACCAAGTG CTCATCAGCT GTGACACGGG CTACAAAGTG 
CTAAAGGATA ACGAGGTGAT GGACACATTC CAAATTGAGT GTCTGAAGGA TGGTGCATGG 
AGTAACAAGA TTCCCACCTG TAAAATTGTA GACTGTGGAG TTCCAGCAGT GCTGAAACAT 
GGGCTAGTAA CCTTCTCCAC AAGAAACAAC CTCACCACGT ACAAATCTGA GATAAGGTAC 
TCCTGCCAGC AACCCTATTA CAAGATGCTT CACAATACCA CAGGTGTATA TACATGTTCT 
GCTCATGGGA CCTGGACAAA TGAAGTGCTC AAGAGAAGCC TGCCCACCTG CCTTCCAGTA 
TGTGGGCAGC CCTCCCGCGC CCTGCCAAAC CTGGTGAAGA GAATTATCGG CGGTCGGAAC 
GCTGAGCTTG GCCTCTTCCC GTGGCAGGCC CTCATAGTGG TGGAAGACAC ATCAAGGATA 
CCAAACGACA AGTGGTTTGG GAGCGGGGCC CTGCTCTCTG AATCCTGGAT ACTCACAGCA 
GCCCACGTGC TGCGTTCCCA GCGCAGAGAC AACACAGTCA TACCTGTCTC AAAGGACCAT 
GTCACTGTCT ACCTGGGCCT ACATGATGTG CGGGACAAGT CAGGAGCCGT CAATAGCTCT 
GCTGCCCGAG TGGTACTCCA TCCAGACTTC AACATCCAGA ACTACAACCA TGACATAGCT 
CTGGTACAAC TGCAGGAGCC TGTGCCCTTG GGAGCCCACG TCATGCCCAT CTGTCTCCCG 
AGACCTGAGC CTGAGGGTCC AGCCCCTCAC ATGTTGGGAC TGGTAGCTGG CTGGGGCATC 
TCCAACCCTA ATGTGACAGT GGATGAGATC ATCATCAGTG GCACGCGAAC CTTGTCAGAT 
GTCCTACAGT ATGTCAAACT ACCCGTGGTG TCACATGCGG AATGCAAAGC CAGCTATGAA 
TCTCGTTCGG GCAACTACAG CGTCACAGAG AACATGTTCT GCGCTGGCTA CTATGAGGGT 
GGCAAGGATA CATGCCTTGG GGATAGTGGT GGGGCCTTCG TCATCTTCGA TGAGATGAGC 
CAGCGCTGGG TAGCCCAAGG CCTGGTGTCC TGGGGAGGAC CTGAAGAATG TGGGAGCAAG 
CAAGTATATG GAGTCTACAC AAAGGTCTCC AACTATGTAG ACTGGCTATT GGAGGAGATG 
AACTCCCCCA GGGGTGTCAG GGAGCTCCAG GTGGAACGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248588.1
CDS	343..2544
Translation	MRFLSFRRLLLYHVLCLTLTEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEGFRVQLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVTLQFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQSHSIQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLISCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKIVDCGVPAVLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGQPSRALPNLVKRIIGGRNAELGLFPWQALIVVEDTSRIPNDKWFGSGALLSESWILTAAHVLRSQRRDNTVIPVSKDHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGAHVMPICLPRPEPEGPAPHMLGLVAGWGISNPNVTVDEIIISGTRTLSDVLQYVKLPVVSHAECKASYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDEMSQRWVAQGLVSWGGPEECGSKQVYGVYTKVSNYVDWLLEEMNSPRGVRELQVER

Target ORF information:

RefSeq Version	XM_006248526.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248526.3

ORF Insert Sequence:

ATGAGGTTCC TGTCTTTCAG ACGGCTCCTC CTCTACCATG TTCTGTGCCT CACCCTGACG 
GAGGTTTCAG CCCATACCGT GGAGCTAAAT GAAATGTTTG GCCAGATCCA GTCCCCTGGC 
TATCCGGATT CCTATCCGAG TGACTCGGAG GTGACCTGGA ATATTACTGT CCCGGAGGGG 
TTCCGGGTCC AGCTTTACTT CATGCACTTC AACTTGGAAT CCTCCTACCT TTGTGAATAT 
GACTATGTGA AGGTAGAAAC CGAAGACCAG GTGCTGGCAA CCTTCTGTGG CAGGGAGACC 
ACCGATACCG AGCAGACCCC GGGCCAGGAA GTGGTTCTTT CGCCTGGTTC CTTTATGTCT 
GTCACTTTCC GGTCAGATTT CTCCAATGAG GAACGATTCA CAGGTTTTGA CGCCCACTAC 
ATGGCTGTAG ATGTGGATGA GTGCAAGGAA AGGGAAGATG AGGAGCTGTC CTGTGACCAC 
TACTGCCACA ACTACATCGG CGGCTACTAC TGCTCCTGTC GCTTTGGCTA CATCCTCCAC 
ACAGACAACA GGACCTGCCG AGTGGAATGC AGTGGCAATC TCTTTACCCA GAGGACAGGC 
ACAATCACCA GCCCGGATTA CCCCAACCCT TACCCCAAGA GCTCTGAATG TTCCTATACC 
ATTGACCTGG AGGAGGGCTT CATGGTTACC CTGCAGTTTG AGGACATTTT TGACATTGAA 
GACCATCCCG AGGTGCCCTG TCCCTATGAC TACATTAAGA TTAAAGCTGG TTCAAAAGTA 
TGGGGACCCT TCTGTGGAGA GAAATCCCCA GAACCAATCA GCACCCAGAG TCATAGCATC 
CAGATCCTAT TTCGCAGCGA CAATTCAGGA GAGAACCGAG GCTGGAGGCT CTCCTACAGG 
GCTGCAGGAA ATGAGTGCCC AAAGCTACAA CCCCCCGTGT ATGGGAAAAT TGAACCCTCG 
CAAGCCGTGT ACTCCTTCAA AGACCAAGTG CTCATCAGCT GTGACACGGG CTACAAAGTG 
CTAAAGGATA ACGAGGTGAT GGACACATTC CAAATTGAGT GTCTGAAGGA TGGTGCATGG 
AGTAACAAGA TTCCCACCTG TAAAATTGTA GACTGTGGAG TTCCAGCAGT GCTGAAACAT 
GGGCTAGTAA CCTTCTCCAC AAGAAACAAC CTCACCACGT ACAAATCTGA GATAAGGTAC 
TCCTGCCAGC AACCCTATTA CAAGATGCTT CACAATACCA CAGGTGTATA TACATGTTCT 
GCTCATGGGA CCTGGACAAA TGAAGTGCTC AAGAGAAGCC TGCCCACCTG CCTTCCAGTA 
TGTGGGCAGC CCTCCCGCGC CCTGCCAAAC CTGGTGAAGA GAATTATCGG CGGTCGGAAC 
GCTGAGCTTG GCCTCTTCCC GTGGCAGGCC CTCATAGTGG TGGAAGACAC ATCAAGGATA 
CCAAACGACA AGTGGTTTGG GAGCGGGGCC CTGCTCTCTG AATCCTGGAT ACTCACAGCA 
GCCCACGTGC TGCGTTCCCA GCGCAGAGAC AACACAGTCA TACCTGTCTC AAAGGACCAT 
GTCACTGTCT ACCTGGGCCT ACATGATGTG CGGGACAAGT CAGGAGCCGT CAATAGCTCT 
GCTGCCCGAG TGGTACTCCA TCCAGACTTC AACATCCAGA ACTACAACCA TGACATAGCT 
CTGGTACAAC TGCAGGAGCC TGTGCCCTTG GGAGCCCACG TCATGCCCAT CTGTCTCCCG 
AGACCTGAGC CTGAGGGTCC AGCCCCTCAC ATGTTGGGAC TGGTAGCTGG CTGGGGCATC 
TCCAACCCTA ATGTGACAGT GGATGAGATC ATCATCAGTG GCACGCGAAC CTTGTCAGAT 
GTCCTACAGT ATGTCAAACT ACCCGTGGTG TCACATGCGG AATGCAAAGC CAGCTATGAA 
TCTCGTTCGG GCAACTACAG CGTCACAGAG AACATGTTCT GCGCTGGCTA CTATGAGGGT 
GGCAAGGATA CATGCCTTGG GGATAGTGGT GGGGCCTTCG TCATCTTCGA TGAGATGAGC 
CAGCGCTGGG TAGCCCAAGG CCTGGTGTCC TGGGGAGGAC CTGAAGAATG TGGGAGCAAG 
CAAGTATATG GAGTCTACAC AAAGGTCTCC AACTATGTAG ACTGGCTATT GGAGGAGATG 
AACTCCCCCA GGGGTGTCAG GGAGCTCCAG GTGGAACGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure (London, England : 1993)25(2)364-375(2017 02)
Nan R,Furze CM,Wright DW,Gor J,Wallis R,Perkins SJ

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation.
Structure (London, England : 1993)19(11)1635-43(2011 Nov)
Gingras AR,Girija UV,Keeble AH,Panchal R,Mitchell DA,Moody PC,Wallis R

Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins.
The Journal of biological chemistry283(37)25715-24(2008 Sep)
Teillet F,Gaboriaud C,Lacroix M,Martin L,Arlaud GJ,Thielens NM

Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.
Journal of immunology (Baltimore, Md. : 1950)180(9)6132-8(2008 May)
Takahashi M,Iwaki D,Kanno K,Ishida Y,Xiong J,Matsushita M,Endo Y,Miura S,Ishii N,Sugamura K,Fujita T

Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.
International immunology19(2)141-9(2007 Feb)
M?ller-Kristensen M,Thiel S,Sj?holm A,Matsushita M,Jensenius JC

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Masp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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