Ramp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ramp1
Entrez Gene ID	58965
Full Name	receptor activity modifying protein 1
General protein information	Preferred Names receptor activity modifying protein 1 Names receptor activity-modifying protein 1 receptor (G protein-coupled) activity modifying protein 1 receptor (calcitonin) activity modifying protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q36
Summary	transports calcitonin receptor-like receptor (Calcr) to the cell membrane and determine its glycosylation state and ligand specificity as a functional calcitonin gene-related peptide (CGRP) receptor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006245473.3	XP_006245535.1	receptor activity-modifying protein 1 isoform X1
XM_006245474.3	XP_006245536.1	receptor activity-modifying protein 1 isoform X2
XM_017596613.1	XP_017452102.1	receptor activity-modifying protein 1 isoform X2
XM_017596614.1	XP_017452103.1	receptor activity-modifying protein 1 isoform X2
NM_031645.1	NP_113833.1	receptor activity-modifying protein 1 precursor
XM_017596612.1	XP_017452101.1	receptor activity-modifying protein 1 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RAMP1	XP_005635995.1
	RAMP1	XP_001117343.2
Homo sapiens (human)	RAMP1	NP_005846.1
Mus musculus (house mouse)	Ramp1	NP_058590.1
Pan troglodytes (chimpanzee)	RAMP1	XP_516183.2
Rattus norvegicus (Norway rat)	Ramp1	NP_113833.1
Danio rerio (zebrafish)	zgc:91818	NP_001002693.1
Xenopus tropicalis (tropical clawed frog)	ramp1	NP_001072813.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.
Meng Q, Shi D, Feng J, Su Y, Long Y, He S, Wang S, Wang Y, Zhang X, Chen X
Annals of clinical and laboratory science46(1)5-17(2016)

Amyloid ? (A?) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways.
Fu W, Ruangkittisakul A, MacTavish D, Shi JY, Ballanyi K, Jhamandas JH
The Journal of biological chemistry287(22)18820-30(2012 May)

Increase of CGRP-containing nerve fibers in the rat periodontal ligament after luxation.
Nagayama T, Seiryu M, Deguchi T, Kano M, Suzuki T, Takano-Yamamoto T, Ichikawa H
Cellular and molecular neurobiology32(3)391-7(2012 Apr)

Calcitonin gene-related peptide and its receptor components in the human sphenopalatine ganglion -- interaction with the sensory system.
Csati A, Tajti J, Tuka B, Edvinsson L, Warfvinge K
Brain research143529-39(2012 Jan)

Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat.
Edvinsson L, Eftekhari S, Salvatore CA, Warfvinge K
Molecular and cellular neurosciences46(1)333-9(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increased expression of IMD and all its receptor components (CRLR, RAMP1, RAMP2, and RAMP3) were displayed within the aorta of rats with Hypercholesterolemia.
Title: Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.

After traumatic injury to periodontal ligament, CGRP nerve fibers appear in close vicinity of small and large receptor activity modifying protein (RAMP)1 cells at 5-7 days.
Title: Increase of CGRP-containing nerve fibers in the rat periodontal ligament after luxation.

The present finding demonstrated that RAMP1 immunoreactivity was localized in many neurons and phenopalatine ganglion.
Title: Calcitonin gene-related peptide and its receptor components in the human sphenopalatine ganglion -- interaction with the sensory system.

Data demonstrate that there is a rich expression of calcitonin gene-related peptide (CGRP) and its receptor elements CLR and RAMP1 in the cerebellum which points towards a functional role of CGRP in cerebellar Purkinje cells.
Title: Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat.

ADM peptide concentration exhibited a spatio-temporal pattern in the rat female reproductive system during gestation and this suggests that ADM may play important roles in gestation.
Title: Coexpression of adrenomedullin and its receptor component proteins in the reproductive system of the rat during gestation.

The following Ramp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ramp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa08358	NM_031645.1 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa32551	XM_006245474.3 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa32551	XM_017596613.1 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa32551	XM_017596612.1 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa32551	XM_017596614.1 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa32550	XM_006245473.3 Latest version!	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ramp1 ( NM_031645.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113833.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), mRNA.

Price & Availability↑

CloneID	ORa08358
Clone ID Related Accession (Same CDS sequence)	NM_031645.1
Accession Version	NM_031645.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB042887.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB042887.1, DV720488.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCCCG GCCTGCGGGG CCTCCCGCGG CGCGGCCTCT GGCTGCTGCT GGCTCATCAT 
CTCTTCATGG TCACTGCCTG CCGGGACCCT GACTATGGTA CTCTCATCCA GGAGCTGTGT 
CTCAGCCGCT TCAAAGAGGA CATGGAGACC ATAGGGAAGA CTCTGTGGTG TGACTGGGGA 
AAGACCATAG GGAGCTATGG GGAGCTCACT CACTGCACCA AACTCGTGGC AAACAAGATT 
GGCTGTTTCT GGCCCAATCC GGAAGTGGAC AAGTTCTTCA TTGCTGTCCA CCACCGCTAC 
TTCAGCAAGT GCCCAGTCTC GGGCAGGGCC CTGCGGGACC CTCCCAACAG CATCCTCTGC 
CCTTTCATTG TGCTCCCCAT TACGGTCACA CTGCTCATGA CTGCCCTGGT GGTCTGGAGG 
AGCAAGCGCA CAGAGGGCAT CGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113833.1
CDS	40..486
Translation	MAPGLRGLPRRGLWLLLAHHLFMVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	NM_031645.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031645.1

ORF Insert Sequence:

ATGGCCCCCG GCCTGCGGGG CCTCCCGCGG CGCGGCCTCT GGCTGCTGCT GGCTCATCAT 
CTCTTCATGG TCACTGCCTG CCGGGACCCT GACTATGGTA CTCTCATCCA GGAGCTGTGT 
CTCAGCCGCT TCAAAGAGGA CATGGAGACC ATAGGGAAGA CTCTGTGGTG TGACTGGGGA 
AAGACCATAG GGAGCTATGG GGAGCTCACT CACTGCACCA AACTCGTGGC AAACAAGATT 
GGCTGTTTCT GGCCCAATCC GGAAGTGGAC AAGTTCTTCA TTGCTGTCCA CCACCGCTAC 
TTCAGCAAGT GCCCAGTCTC GGGCAGGGCC CTGCGGGACC CTCCCAACAG CATCCTCTGC 
CCTTTCATTG TGCTCCCCAT TACGGTCACA CTGCTCATGA CTGCCCTGGT GGTCTGGAGG 
AGCAAGCGCA CAGAGGGCAT CGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ramp1 ( XM_006245474.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245536.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa32551
Clone ID Related Accession (Same CDS sequence)	XM_006245474.3 , XM_017596613.1 , XM_017596614.1 , XM_017596612.1
Accession Version	XM_006245474.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245474.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245536.1
CDS	181..561
Translation	MVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	XM_006245474.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245474.3

ORF Insert Sequence:

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ramp1 ( XM_017596613.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452102.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa32551
Clone ID Related Accession (Same CDS sequence)	XM_006245474.3 , XM_017596613.1 , XM_017596614.1 , XM_017596612.1
Accession Version	XM_017596613.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452102.1
CDS	918..1298
Translation	MVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	XM_017596613.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596613.1

ORF Insert Sequence:

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ramp1 ( XM_017596614.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452103.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa32551
Clone ID Related Accession (Same CDS sequence)	XM_006245474.3 , XM_017596613.1 , XM_017596614.1 , XM_017596612.1
Accession Version	XM_017596614.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452103.1
CDS	328..708
Translation	MVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	XM_017596614.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596614.1

ORF Insert Sequence:

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ramp1 ( XM_017596612.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452101.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa32551
Clone ID Related Accession (Same CDS sequence)	XM_006245474.3 , XM_017596613.1 , XM_017596614.1 , XM_017596612.1
Accession Version	XM_017596612.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452101.1
CDS	38..418
Translation	MVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	XM_017596612.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596612.1

ORF Insert Sequence:

ATGGTCACTG CCTGCCGGGA CCCTGACTAT GGTACTCTCA TCCAGGAGCT GTGTCTCAGC 
CGCTTCAAAG AGGACATGGA GACCATAGGG AAGACTCTGT GGTGTGACTG GGGAAAGACC 
ATAGGGAGCT ATGGGGAGCT CACTCACTGC ACCAAACTCG TGGCAAACAA GATTGGCTGT 
TTCTGGCCCA ATCCGGAAGT GGACAAGTTC TTCATTGCTG TCCACCACCG CTACTTCAGC 
AAGTGCCCAG TCTCGGGCAG GGCCCTGCGG GACCCTCCCA ACAGCATCCT CTGCCCTTTC 
ATTGTGCTCC CCATTACGGT CACACTGCTC ATGACTGCCC TGGTGGTCTG GAGGAGCAAG 
CGCACAGAGG GCATCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ramp1 ( XM_006245473.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245535.1 Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa32550
Clone ID Related Accession (Same CDS sequence)	XM_006245473.3
Accession Version	XM_006245473.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor activity-modifying protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245473.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCCTGA GCCTGGGACC TGGGCTCAGT CCTGGGGTCA CTGCCCATTG CTGCAGTGGG 
TTCCCTGGTC CCCAGAGCAC TCATCATCTC TTCATGGTCA CTGCCTGCCG GGACCCTGAC 
TATGGTACTC TCATCCAGGA GCTGTGTCTC AGCCGCTTCA AAGAGGACAT GGAGACCATA 
GGGAAGACTC TGTGGTGTGA CTGGGGAAAG ACCATAGGGA GCTATGGGGA GCTCACTCAC 
TGCACCAAAC TCGTGGCAAA CAAGATTGGC TGTTTCTGGC CCAATCCGGA AGTGGACAAG 
TTCTTCATTG CTGTCCACCA CCGCTACTTC AGCAAGTGCC CAGTCTCGGG CAGGGCCCTG 
CGGGACCCTC CCAACAGCAT CCTCTGCCCT TTCATTGTGC TCCCCATTAC GGTCACACTG 
CTCATGACTG CCCTGGTGGT CTGGAGGAGC AAGCGCACAG AGGGCATCGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245535.1
CDS	876..1349
Translation	MFLSLGPGLSPGVTAHCCSGFPGPQSTHHLFMVTACRDPDYGTLIQELCLSRFKEDMETIGKTLWCDWGKTIGSYGELTHCTKLVANKIGCFWPNPEVDKFFIAVHHRYFSKCPVSGRALRDPPNSILCPFIVLPITVTLLMTALVVWRSKRTEGIV

Target ORF information:

RefSeq Version	XM_006245473.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor activity modifying protein 1 (Ramp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245473.3

ORF Insert Sequence:

ATGTTCCTGA GCCTGGGACC TGGGCTCAGT CCTGGGGTCA CTGCCCATTG CTGCAGTGGG 
TTCCCTGGTC CCCAGAGCAC TCATCATCTC TTCATGGTCA CTGCCTGCCG GGACCCTGAC 
TATGGTACTC TCATCCAGGA GCTGTGTCTC AGCCGCTTCA AAGAGGACAT GGAGACCATA 
GGGAAGACTC TGTGGTGTGA CTGGGGAAAG ACCATAGGGA GCTATGGGGA GCTCACTCAC 
TGCACCAAAC TCGTGGCAAA CAAGATTGGC TGTTTCTGGC CCAATCCGGA AGTGGACAAG 
TTCTTCATTG CTGTCCACCA CCGCTACTTC AGCAAGTGCC CAGTCTCGGG CAGGGCCCTG 
CGGGACCCTC CCAACAGCAT CCTCTGCCCT TTCATTGTGC TCCCCATTAC GGTCACACTG 
CTCATGACTG CCCTGGTGGT CTGGAGGAGC AAGCGCACAG AGGGCATCGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypercholesterolemia Up-Regulates the Expression of Intermedin and Its Receptor Components in the Aorta of Rats via Inducing the Oxidative Stress.
Annals of clinical and laboratory science46(1)5-17(2016)
Meng Q,Shi D,Feng J,Su Y,Long Y,He S,Wang S,Wang Y,Zhang X,Chen X

Amyloid ? (A?) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways.
The Journal of biological chemistry287(22)18820-30(2012 May)
Fu W,Ruangkittisakul A,MacTavish D,Shi JY,Ballanyi K,Jhamandas JH

Increase of CGRP-containing nerve fibers in the rat periodontal ligament after luxation.
Cellular and molecular neurobiology32(3)391-7(2012 Apr)
Nagayama T,Seiryu M,Deguchi T,Kano M,Suzuki T,Takano-Yamamoto T,Ichikawa H

Calcitonin gene-related peptide and its receptor components in the human sphenopalatine ganglion -- interaction with the sensory system.
Brain research143529-39(2012 Jan)
Csati A,Tajti J,Tuka B,Edvinsson L,Warfvinge K

Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat.
Molecular and cellular neurosciences46(1)333-9(2011 Jan)
Edvinsson L,Eftekhari S,Salvatore CA,Warfvinge K

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Ramp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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