Tmem67 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem67
Entrez Gene ID	313067
Full Name	transmembrane protein 67
Synonyms	Mks3,Wpk
General protein information	Preferred Names transmembrane protein 67 Names meckelin Meckel syndrome type 3 protein homolog Wistar polycystic kidney
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q13
Summary	Meckelin is mutated in the wpk rat. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107916.2	NP_001101386.3	meckelin

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	tmem67	XP_700974.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002548	XP_312391.5
Pan troglodytes (chimpanzee)	TMEM67	XP_528307.2
Caenorhabditis elegans (roundworm)	mks-3	NP_495591.2
Homo sapiens (human)	TMEM67	NP_714915.3
Mus musculus (house mouse)	Tmem67	NP_808529.2
Xenopus tropicalis (tropical clawed frog)	tmem67	XP_002934466.2
	TMEM67	XP_002805487.1
Bos taurus (cattle)	TMEM67	NP_001192228.1
Rattus norvegicus (Norway rat)	Tmem67	NP_001101386.3
Canis lupus familiaris (dog)	TMEM67	XP_544178.4
Gallus gallus (chicken)	TMEM67	XP_418334.3
Drosophila melanogaster (fruit fly)	CG15923	NP_001097846.1

Gene Ontology
Bibliography

Related articles in PubMed

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert?syndrome.
Lambacher NJ, Bruel AL, van Dam TJ, Szyma?ska K, Slaats GG, Kuhns S, McManus GJ, Kennedy JE, Gaff K, Wu KM, van der Lee R, Burglen L, Doummar D, Rivi?re JB, Faivre L, Atti?-Bitach T, Saunier S, Curd A, Peckham M, Giles RH, Johnson CA, Huynen MA, Thauvin-Robinet C, Blacque OE
Nature cell biology18(1)122-31(2016 Jan)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

A missense mutation in TMEM67 causes Meckel-Gruber syndrome type 3 (MKS3): a family from China.
Zhang M, Cheng J, Liu A, Wang L, Xiong L, Chen M, Sun Y, Li J, Lu Y, Yuan H, Li Y, Lu Y
International journal of clinical and experimental pathology8(5)5379-86(2015)

Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome.
Tiwari S, Hudson S, Gattone VH 2nd, Miller C, Chernoff EA, Belecky-Adams TL
PloS one8(3)e59306(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data conclude that MKS3 is not important for formation of connecting cilium and rudimentary outer segments, but is critical for the maturation of outer segment processes.
Title: Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome.

MKS1 and MKS3 functions are required for ciliary structure and function.
Title: Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3.

We have refined MKS3 mapping to a 12.67-Mb interval (8q21.13-q22.1) that is syntenic to the Wpk locus in rat, which is a model with polycystic kidney disease, agenesis of the corpus callosum and hydrocephalus.
Title: The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.

The following Tmem67 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem67 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06278	NM_001107916.2 Latest version!	Rattus norvegicus transmembrane protein 67 (Tmem67), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem67 ( NM_001107916.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101386.3 Rattus norvegicus transmembrane protein 67 (Tmem67), mRNA.

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CloneID	ORa06278
Clone ID Related Accession (Same CDS sequence)	NM_001107916.2
Accession Version	NM_001107916.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2994bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Rattus norvegicus(Norway rat)
Product	meckelin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07047262.1 and AABR07047261.1. On May 30, 2008 this sequence version replaced NM_001107916.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGTATGG GTACCATGGT GATGCGTACA AGGCCTTTGG CGGCCATGGC GGTCAGGTCC 
TGTTTTTCAG CTCTGACTGG CACTGTGTAC CTTCTCTTGG TTCTTTGCGA AGTCTCATGG 
GCCCAAATCT TCTCCTTCCC TTTCCAGCGG CCGGAGACTT GCGATCTCAA CCAGTACTTC 
GACATCTCGG CGCTCTCCTG TGCCCCCTGT GGAGCCAACC AGCGGAGGGA CGCACTGGGA 
ACTTCCTGTA TATGTCTACC AGGATATCAT ATGATTTCTA ATAATGGAGG ACCTTCCATT 
ATTTGTAAAA AGTGTCCAGA AAACATGAAA GGTGTTACCA AAGATGGCTG GGACTGCATT 
TCTTGCCCTA ATGGTTTAAC TGCTGAGGGG AAGTGCCACT GTCCCAGTGG CCATATATTA 
GTGGAAAGAA ATGTTAGCGG GTCTTTGTTA TCCCAAGCAA CTTGTGAGCT TTGTGATGGA 
AATGAAAACT CGTTTACAAA ACCCAATGCT TTAGGAGTCA GGTGTGTCCG CTGCGAACCA 
ACATTCGTGA ATACAAGCCG GTCGTGTTCA TGTTCAGAGC CTCACATTTC GACAGGTGGA 
TTATGTTTCA GCAACACAGG GAATTTTCCT CAACGTTTAA TTTCCACTGA ACGTTATGGC 
GAGCTTGGCA TGTCATCAAA CTCAGAATGG TTTACAAAGT ATTTGCAGGC AACAGCAGCT 
GCATGCTGGA CTCACAGCAA CCTGACATCT TGCCAAGCTC TCGGGAATAT GTGCGTGATG 
AACATGAACT CTTACGACTC GACTACATTC GATGCTTGCC GACTGTTCCA CTACGTCTTC 
GAAGGCGCTG CTGGGCTGAC CGGCGTGCAT TCTGTCCCGT TCTGGAGACA GAACCTTCCT 
TGGCTGTTTT ACGGAGACCA GCCAGGATTG GCTTCTCAAG TTCTCAGTAC TACCCCTCTT 
CCTACAAATT TCAGTTTTAA AGGACAAAAC CAGCTGAAGT TTGTTGCTGC TTCCTACGAT 
ATACGAGGAA ACTTCATCAG ATGGCAAACT GTAAAAGGTG GTGTTCTACA GCTTTGTCCA 
GACACCGAGA GAAGACTAGA TGCTGCATAT TCTTTTGGAA CAACGTACCA GCAAAACTGT 
GAAATCTCTC TCTCTAAACT CCTGGCTGAC TTTCCCAGTC CTGTGTTTTA TGATATTTAC 
CTGGAATATA CTGATGAAGT GCAACATCAT TACCTTTGGG CTATCCCAGT GTTAAACCTC 
AATCTTCAAC ATAATAAACT GTTTGTGAAC CAAGACAGTA GCTCCAGCAA GTGGCTTCTG 
ACTCGGCGCA TTTTCTTAGT GGATGCAGTA AGTGGACGAG AAAATGACCT AGGAAATCAG 
CCAAGAGTAA TTCGAGTTGC TACCCAGATA TCACTGAGCA TACGCCTTGT ACCCAACACA 
AAGAATGGAA ACATCTACAC TCCCTTACTC ACCATTGCCT ACAGTGACAT TGACATCAAA 
AATGCTTATA GCCAGTCTGT GAAGATTTCC TTCTCAGTGA AATATGAGAT GAATCAAGGA 
GATGCATTTG TCCAGACAGA TATTGCTTTG GGTGTGTTGG GCGGGCTGGC TGTGCTATCA 
TCTCTCTTGA AGACGGCAGG GTGGAAGAGA CGCATTGGGA GCCCCATGAT TGACCTACAG 
ACAGTTATGA AATTCCTGCT GTACTACGCT GGTGACCTGG CCAATGTGTT TTTCATCATC 
ACTGTGGGGA CAGGGCTTTA TTGGCTTATT TTCTTCAAAG CACAGAAGTC TGTCTCTGTT 
TTGCTGCCGA TGCCGGTTCA GGAAGAACGT TTCGTTACTT ATGTGGGGTG TGCCTTTGCT 
ATGAAGGCTC TACAATTTTT GCACAAGCTC ATATCCCAGA TTACCATAGA TATATTCTTT 
ATTGATTGGG AACGGCCGAA AGGAAAAGTT CTCAAAGCTG TCGAAGGTGA GGGTGGTGTG 
CGGAGTGCCA CTGTTCCTGT GAGCATATGG AGAACGTATT TTGTGGCAAA TGAATGGAAC 
GAGATTCAGA CTGTGAGAAA AATCAATCCA CTCTTTCAAG TACTTACCAC GCTCTTCTTC 
TTGGAGGTGG TGGGATTCAA AAACTTAGCG TTAATGGATC CATCCTCGAG CCTTTCTAGA 
AGCCTGTCAG ACTACGCAGC TCCTTACAGT CGCATTTTGA GATACGCTGT GGCTACCACT 
ATCTGGCTGG TGATCGGAAT AGTCCAGGCT GTTTTCTTTG CTGCCTTTTA TGAGAGATTC 
ATAGAAGACA AAATCCGGCA GTTCGTTGAC CTGTGCTCCA TGAGTAACGT GTCAGTGTTC 
CTGCTGTCCC ACAGATGTTT TGGATATTAC ATTCACGGCA GGTCAGTCCA CGGCCATGCG 
GACACCAACA TGGAGGACAT GAACATGAAC CTGAGGCGAG AGGCGGAAAA TTTGTGCAGT 
CAAAGAGGTT TGGTGCCCAA CACAGATGGG CAGACGTTTC AGATTGCCGT TTCCAGTCAG 
ATGAGACAGC ACTATGACAG AATTCACGAG ACATTAACAA GGAGAAATGG CCCTGCCAGA 
CTGCTGAGCT CATCAGGGAG TACCTTGGAA CAAAGTATAA AGGCATACCA CGCAATGAAT 
AAGTTCCTCG GCTCTTTCAT TGACCACGTT CATAAGGAAA TGGATTACTT CATAAAAGAC 
AAGTTGCTTC TCGAAAAGAT CCTCGGGATG GAGTTCATGG AGCCCCTGGA GAAGAGCATC 
TTCTACAATG ATGAAAGTCA TTCTTTCAGC AGTGTGCTGT ATTATGGGAA CGAGGCCACT 
CTCCTTATCT TTGATCTGTT GTTCTTCTGT GTCGTGGACT TGGCTTGCCA GAACTTTGTT 
TTAGCATCCT TCCTCACCTA CCTGCAGCAA GAGATTTTTC GATTTATCCG AAATACAGTA 
GGACAAAAGA ATTTAGCAAC CAAAACACTA GTGGATGAAA GATTTCTGAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101386.3
CDS	6..2999
Translation	MGMGTMVMRTRPLAAMAVRSCFSALTGTVYLLLVLCEVSWAQIFSFPFQRPETCDLNQYFDISALSCAPCGANQRRDALGTSCICLPGYHMISNNGGPSIICKKCPENMKGVTKDGWDCISCPNGLTAEGKCHCPSGHILVERNVSGSLLSQATCELCDGNENSFTKPNALGVRCVRCEPTFVNTSRSCSCSEPHISTGGLCFSNTGNFPQRLISTERYGELGMSSNSEWFTKYLQATAAACWTHSNLTSCQALGNMCVMNMNSYDSTTFDACRLFHYVFEGAAGLTGVHSVPFWRQNLPWLFYGDQPGLASQVLSTTPLPTNFSFKGQNQLKFVAASYDIRGNFIRWQTVKGGVLQLCPDTERRLDAAYSFGTTYQQNCEISLSKLLADFPSPVFYDIYLEYTDEVQHHYLWAIPVLNLNLQHNKLFVNQDSSSSKWLLTRRIFLVDAVSGRENDLGNQPRVIRVATQISLSIRLVPNTKNGNIYTPLLTIAYSDIDIKNAYSQSVKISFSVKYEMNQGDAFVQTDIALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQTVMKFLLYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHKLISQITIDIFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGFKNLALMDPSSSLSRSLSDYAAPYSRILRYAVATTIWLVIGIVQAVFFAAFYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYYIHGRSVHGHADTNMEDMNMNLRREAENLCSQRGLVPNTDGQTFQIAVSSQMRQHYDRIHETLTRRNGPARLLSSSGSTLEQSIKAYHAMNKFLGSFIDHVHKEMDYFIKDKLLLEKILGMEFMEPLEKSIFYNDESHSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFVLASFLTYLQQEIFRFIRNTVGQKNLATKTLVDERFLI

Target ORF information:

RefSeq Version	NM_001107916.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane protein 67 (Tmem67), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107916.2

ORF Insert Sequence:

ATGGGTATGG GTACCATGGT GATGCGTACA AGGCCTTTGG CGGCCATGGC GGTCAGGTCC 
TGTTTTTCAG CTCTGACTGG CACTGTGTAC CTTCTCTTGG TTCTTTGCGA AGTCTCATGG 
GCCCAAATCT TCTCCTTCCC TTTCCAGCGG CCGGAGACTT GCGATCTCAA CCAGTACTTC 
GACATCTCGG CGCTCTCCTG TGCCCCCTGT GGAGCCAACC AGCGGAGGGA CGCACTGGGA 
ACTTCCTGTA TATGTCTACC AGGATATCAT ATGATTTCTA ATAATGGAGG ACCTTCCATT 
ATTTGTAAAA AGTGTCCAGA AAACATGAAA GGTGTTACCA AAGATGGCTG GGACTGCATT 
TCTTGCCCTA ATGGTTTAAC TGCTGAGGGG AAGTGCCACT GTCCCAGTGG CCATATATTA 
GTGGAAAGAA ATGTTAGCGG GTCTTTGTTA TCCCAAGCAA CTTGTGAGCT TTGTGATGGA 
AATGAAAACT CGTTTACAAA ACCCAATGCT TTAGGAGTCA GGTGTGTCCG CTGCGAACCA 
ACATTCGTGA ATACAAGCCG GTCGTGTTCA TGTTCAGAGC CTCACATTTC GACAGGTGGA 
TTATGTTTCA GCAACACAGG GAATTTTCCT CAACGTTTAA TTTCCACTGA ACGTTATGGC 
GAGCTTGGCA TGTCATCAAA CTCAGAATGG TTTACAAAGT ATTTGCAGGC AACAGCAGCT 
GCATGCTGGA CTCACAGCAA CCTGACATCT TGCCAAGCTC TCGGGAATAT GTGCGTGATG 
AACATGAACT CTTACGACTC GACTACATTC GATGCTTGCC GACTGTTCCA CTACGTCTTC 
GAAGGCGCTG CTGGGCTGAC CGGCGTGCAT TCTGTCCCGT TCTGGAGACA GAACCTTCCT 
TGGCTGTTTT ACGGAGACCA GCCAGGATTG GCTTCTCAAG TTCTCAGTAC TACCCCTCTT 
CCTACAAATT TCAGTTTTAA AGGACAAAAC CAGCTGAAGT TTGTTGCTGC TTCCTACGAT 
ATACGAGGAA ACTTCATCAG ATGGCAAACT GTAAAAGGTG GTGTTCTACA GCTTTGTCCA 
GACACCGAGA GAAGACTAGA TGCTGCATAT TCTTTTGGAA CAACGTACCA GCAAAACTGT 
GAAATCTCTC TCTCTAAACT CCTGGCTGAC TTTCCCAGTC CTGTGTTTTA TGATATTTAC 
CTGGAATATA CTGATGAAGT GCAACATCAT TACCTTTGGG CTATCCCAGT GTTAAACCTC 
AATCTTCAAC ATAATAAACT GTTTGTGAAC CAAGACAGTA GCTCCAGCAA GTGGCTTCTG 
ACTCGGCGCA TTTTCTTAGT GGATGCAGTA AGTGGACGAG AAAATGACCT AGGAAATCAG 
CCAAGAGTAA TTCGAGTTGC TACCCAGATA TCACTGAGCA TACGCCTTGT ACCCAACACA 
AAGAATGGAA ACATCTACAC TCCCTTACTC ACCATTGCCT ACAGTGACAT TGACATCAAA 
AATGCTTATA GCCAGTCTGT GAAGATTTCC TTCTCAGTGA AATATGAGAT GAATCAAGGA 
GATGCATTTG TCCAGACAGA TATTGCTTTG GGTGTGTTGG GCGGGCTGGC TGTGCTATCA 
TCTCTCTTGA AGACGGCAGG GTGGAAGAGA CGCATTGGGA GCCCCATGAT TGACCTACAG 
ACAGTTATGA AATTCCTGCT GTACTACGCT GGTGACCTGG CCAATGTGTT TTTCATCATC 
ACTGTGGGGA CAGGGCTTTA TTGGCTTATT TTCTTCAAAG CACAGAAGTC TGTCTCTGTT 
TTGCTGCCGA TGCCGGTTCA GGAAGAACGT TTCGTTACTT ATGTGGGGTG TGCCTTTGCT 
ATGAAGGCTC TACAATTTTT GCACAAGCTC ATATCCCAGA TTACCATAGA TATATTCTTT 
ATTGATTGGG AACGGCCGAA AGGAAAAGTT CTCAAAGCTG TCGAAGGTGA GGGTGGTGTG 
CGGAGTGCCA CTGTTCCTGT GAGCATATGG AGAACGTATT TTGTGGCAAA TGAATGGAAC 
GAGATTCAGA CTGTGAGAAA AATCAATCCA CTCTTTCAAG TACTTACCAC GCTCTTCTTC 
TTGGAGGTGG TGGGATTCAA AAACTTAGCG TTAATGGATC CATCCTCGAG CCTTTCTAGA 
AGCCTGTCAG ACTACGCAGC TCCTTACAGT CGCATTTTGA GATACGCTGT GGCTACCACT 
ATCTGGCTGG TGATCGGAAT AGTCCAGGCT GTTTTCTTTG CTGCCTTTTA TGAGAGATTC 
ATAGAAGACA AAATCCGGCA GTTCGTTGAC CTGTGCTCCA TGAGTAACGT GTCAGTGTTC 
CTGCTGTCCC ACAGATGTTT TGGATATTAC ATTCACGGCA GGTCAGTCCA CGGCCATGCG 
GACACCAACA TGGAGGACAT GAACATGAAC CTGAGGCGAG AGGCGGAAAA TTTGTGCAGT 
CAAAGAGGTT TGGTGCCCAA CACAGATGGG CAGACGTTTC AGATTGCCGT TTCCAGTCAG 
ATGAGACAGC ACTATGACAG AATTCACGAG ACATTAACAA GGAGAAATGG CCCTGCCAGA 
CTGCTGAGCT CATCAGGGAG TACCTTGGAA CAAAGTATAA AGGCATACCA CGCAATGAAT 
AAGTTCCTCG GCTCTTTCAT TGACCACGTT CATAAGGAAA TGGATTACTT CATAAAAGAC 
AAGTTGCTTC TCGAAAAGAT CCTCGGGATG GAGTTCATGG AGCCCCTGGA GAAGAGCATC 
TTCTACAATG ATGAAAGTCA TTCTTTCAGC AGTGTGCTGT ATTATGGGAA CGAGGCCACT 
CTCCTTATCT TTGATCTGTT GTTCTTCTGT GTCGTGGACT TGGCTTGCCA GAACTTTGTT 
TTAGCATCCT TCCTCACCTA CCTGCAGCAA GAGATTTTTC GATTTATCCG AAATACAGTA 
GGACAAAAGA ATTTAGCAAC CAAAACACTA GTGGATGAAA GATTTCTGAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert?syndrome.
Nature cell biology18(1)122-31(2016 Jan)
Lambacher NJ,Bruel AL,van Dam TJ,Szyma?ska K,Slaats GG,Kuhns S,McManus GJ,Kennedy JE,Gaff K,Wu KM,van der Lee R,Burglen L,Doummar D,Rivi?re JB,Faivre L,Atti?-Bitach T,Saunier S,Curd A,Peckham M,Giles RH,Johnson CA,Huynen MA,Thauvin-Robinet C,Blacque OE

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

A missense mutation in TMEM67 causes Meckel-Gruber syndrome type 3 (MKS3): a family from China.
International journal of clinical and experimental pathology8(5)5379-86(2015)
Zhang M,Cheng J,Liu A,Wang L,Xiong L,Chen M,Sun Y,Li J,Lu Y,Yuan H,Li Y,Lu Y

Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome.
PloS one8(3)e59306(2013)
Tiwari S,Hudson S,Gattone VH 2nd,Miller C,Chernoff EA,Belecky-Adams TL

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Tmem67 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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