gRNAs
The following Pitrm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pitrm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa11170 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107363.1 | |
| Accession Version | NM_001107363.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2865bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-18 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | presequence protease, mitochondrial | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473990.1. On or before Oct 4, 2007 this sequence version replaced XM_001067446.1, XM_225517.4. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## | |
1 | ATGTGGCGCT TCAGCGGTCG GCGGGGACTG TGCGCTGTAC AGCGACTGAG CAGCGGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001100833.1 |
| CDS | 8..2872 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107363.1 |
1 | ATGTGGCGCT TCAGCGGTCG GCGGGGACTG TGCGCTGTAC AGCGACTGAG CAGCGGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa38012 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006254186.2 | |
| Accession Version | XM_006254186.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3108bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | presequence protease, mitochondrial isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006254186.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGCGCT TCAGCGGTCG GCGGGGACTG TGCGCTGTAC AGCGACTGAG CAGCGGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006254248.1 |
| CDS | 52..3159 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006254186.2 |
1 | ATGTGGCGCT TCAGCGGTCG GCGGGGACTG TGCGCTGTAC AGCGACTGAG CAGCGGGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Defective PITRM1 mitochondrial peptidase is associated with A? amyloidotic neurodegeneration. |
Molecular basis of substrate recognition and degradation by human presequence protease. |
Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP. |
Mammalian pitrilysin: substrate specificity and mitochondrial targeting. |
Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP. |
