DEFB118 cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene
Clones
gRNAs

Summary

Gene Symbol	DEFB118
Entrez Gene ID	741920
Full Name	defensin beta 118
General protein information	Preferred Names defensin beta 118 Names beta-defensin 118
Gene Type	protein-coding
Organism	Pan troglodytes(chimpanzee)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001129766.1	NP_001123238.1	beta-defensin 118 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DEFB118	NP_001123238.1
Homo sapiens (human)	DEFB118	NP_473453.1
	DEFB118	NP_001032421.1

Gene Ontology
Bibliography

Related articles in PubMed

Directional and balancing selection in human beta-defensins.
Hollox EJ, Armour JA
BMC evolutionary biology8113(2008 Apr)

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DEFB118 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB118 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OPc00256	NM_001129766.1 Latest version!	Pan troglodytes defensin beta 118 (DEFB118), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DEFB118 ( NM_001129766.1 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> NP_001123238.1 Pan troglodytes defensin beta 118 (DEFB118), mRNA.

Price & Availability↑

CloneID	OPc00256
Clone ID Related Accession (Same CDS sequence)	NM_001129766.1
Accession Version	NM_001129766.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Pan troglodytes(chimpanzee)
Product	beta-defensin 118 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ012070.1. On Jun 29, 2008 this sequence version replaced XM_001151025.1. ##Evidence-Data-START## Transcript exon combination :: DQ012070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03735001 [ECO:0000348] ##Evidence-Data-END##

ATGAAACTCC TGCTGCTGGC TCTTCCTGTG CTTGTGCTCC TACCCCAAGT GATCCCAGCC 
TATAGTGGTG AAAAAAAATG CTGGAACAGA TCTGGGCACT GCAGGAAACA ATGCAAAGAT 
GGAGAAGCAG TGAAAGATAC ATGCAAAAAT CTTCGAGCTT GCTGCGTTCC ATCCAATGAA 
GACCACAGGC GAGTTCCTAT GACATCTCCC ACACCCTTGA GTGACTCAAC ACCAGGAATT 
ATTGATGATA TTTTAACAGT AAGGTTCACG ACAGACTACT TTGAAGTAAG CAGCAAGAAA 
GATATGGTTG AAGAGTCTGA GGCGGGAAGG GGAACTGAGA CCTCTCTTCC AAATGTTCAC 
CATAGCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123238.1
CDS	1..372
Translation	MKLLLLALPVLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRRVPMTSPTPLSDSTPGIIDDILTVRFTTDYFEVSSKKDMVEESEAGRGTETSLPNVHHSS

Target ORF information:

RefSeq Version	NM_001129766.1
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes defensin beta 118 (DEFB118), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129766.1

ORF Insert Sequence:

ATGAAACTCC TGCTGCTGGC TCTTCCTGTG CTTGTGCTCC TACCCCAAGT GATCCCAGCC 
TATAGTGGTG AAAAAAAATG CTGGAACAGA TCTGGGCACT GCAGGAAACA ATGCAAAGAT 
GGAGAAGCAG TGAAAGATAC ATGCAAAAAT CTTCGAGCTT GCTGCGTTCC ATCCAATGAA 
GACCACAGGC GAGTTCCTAT GACATCTCCC ACACCCTTGA GTGACTCAAC ACCAGGAATT 
ATTGATGATA TTTTAACAGT AAGGTTCACG ACAGACTACT TTGAAGTAAG CAGCAAGAAA 
GATATGGTTG AAGAGTCTGA GGCGGGAAGG GGAACTGAGA CCTCTCTTCC AAATGTTCAC 
CATAGCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Directional and balancing selection in human beta-defensins.
BMC evolutionary biology8113(2008 Apr)
Hollox EJ,Armour JA

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Physiological genomics23(1)5-17(2005 Sep)
Patil AA,Cai Y,Sang Y,Blecha F,Zhang G