IL22 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL22
Entrez Gene ID	718047
Full Name	interleukin 22
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001194724.2	NP_001181653.1	interleukin-22 precursor
NM_001194724.1	NP_001181653.1	interleukin-22 precursor

Pathways from BioSystems

Homologies

	IL22	XP_001117159.1
Mus musculus (house mouse)	Iltifb	NP_473420.2
Rattus norvegicus (Norway rat)	Il22	NP_001178917.1
Homo sapiens (human)	IL22	NP_065386.1
Gallus gallus (chicken)	IL22	NP_001186543.1
Xenopus tropicalis (tropical clawed frog)	il22	NP_001135725.1
Pan troglodytes (chimpanzee)	IL22	XP_003313906.1
Canis lupus familiaris (dog)	IL22	XP_538274.1
Bos taurus (cattle)	IL22	NP_001091849.1
Mus musculus (house mouse)	Il22	NP_058667.1

Gene Ontology
Bibliography

Related articles in PubMed

Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease.
Xu H, Feely SL, Wang X, Liu DX, Borda JT, Dufour J, Li W, Aye PP, Doxiadis GG, Khosla C, Veazey RS, Sestak K
Clinical immunology (Orlando, Fla.)147(1)40-9(2013 Apr)

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, Belkaid Y, Lifson JD, Silvestri G, Milner JD, Paiardini M, Haddad EK, Brenchley JM
Mucosal immunology5(6)646-57(2012 Nov)

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J
Nature biotechnology29(11)1019-23(2011 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
Title: Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease.

Loss of mucosal CD103+ dendritic cells and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
Title: Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.

The following IL22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb01230	NM_001194724.2 Latest version!	Macaca mulatta interleukin 22 (IL22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMb01230	NM_001194724.1	Macaca mulatta interleukin 22 (IL22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL22 ( NM_001194724.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001181653.1 Macaca mulatta interleukin 22 (IL22), mRNA.

Price & Availability↑

CloneID	OMb01230
Clone ID Related Accession (Same CDS sequence)	NM_001194724.2 , NM_001194724.1
Accession Version	NM_001194724.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-22 precursor
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JSUE03007130.1. On Aug 11, 2010 this sequence version replaced XM_001117159.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA4688315, SAMEA4688316 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGCCC TGCAGAAATC TGTGAGCCCT TTCCTTATGG GGACTCTGGC CACCAGCTGC 
CTCCTTCTCT TGGCCCTCTG GGTGCAGGGA GGAGCAGCTG CGCCCGTCAG CTCCCACTGC 
AGGCTTGACA AGTCCAACTT CCAGCAGCCC TATATCACCA ACCGCACCTT CATGCTGGCT 
AAGGAGGCTA GCTCGGCTGA TAACAACACA GACGTTCGTC TCATTGGGGA AAAACTGTTC 
CGCGGAGTCA GTATGAGTGA GCGCTGCTAT CTGATGAAGC AGGTGCTGAA CTTCACCCTT 
GAAGAAGTGC TGCTCCCTCA ATCGGATAGG TTCCAGCCTT ATATGCAGGA GGTGGTGCCC 
TTCCTGGCCA GGCTCAGCAA CAGTCTAAGC ACATGTCACA TTGAAGGTGA TGACCTGCAT 
ATCCAGAAGA ATGTCCAAAA GCTGAAGGAC ACAGTGAAAA AGCTTGGAGA GAGTGGAGAG 
ATCAAAGCAA TTGGAGAACT GGATTTGCTG TTTATGTCTC TGAGAAATGC CTGCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001181653.1
CDS	70..609
Translation	MAALQKSVSPFLMGTLATSCLLLLALWVQGGAAAPVSSHCRLDKSNFQQPYITNRTFMLAKEASSADNNTDVRLIGEKLFRGVSMSERCYLMKQVLNFTLEEVLLPQSDRFQPYMQEVVPFLARLSNSLSTCHIEGDDLHIQKNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI

Target ORF information:

RefSeq Version	NM_001194724.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 22 (IL22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001194724.1

ORF Insert Sequence:

ATGGCCGCCC TGCAGAAATC TGTGAGCCCT TTCCTTATGG GGACTCTGGC CACCAGCTGC 
CTCCTTCTCT TGGCCCTCTG GGTGCAGGGA GGAGCAGCTG CGCCCGTCAG CTCCCACTGC 
AGGCTTGACA AGTCCAACTT CCAGCAGCCC TATATCACCA ACCGCACCTT CATGCTGGCT 
AAGGAGGCTA GCTCGGCTGA TAACAACACA GACGTTCGTC TCATTGGGGA AAAACTGTTC 
CGCGGAGTCA GTATGAGTGA GCGCTGCTAT CTGATGAAGC AGGTGCTGAA CTTCACCCTT 
GAAGAAGTGC TGCTCCCTCA ATCGGATAGG TTCCAGCCTT ATATGCAGGA GGTGGTGCCC 
TTCCTGGCCA GGCTCAGCAA CAGTCTAAGC ACATGTCACA TTGAAGGTGA TGACCTGCAT 
ATCCAGAAGA ATGTCCAAAA GCTGAAGGAC ACAGTGAAAA AGCTTGGAGA GAGTGGAGAG 
ATCAAAGCAA TTGGAGAACT GGATTTGCTG TTTATGTCTC TGAGAAATGC CTGCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL22 ( NM_001194724.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001181653.1 Macaca mulatta interleukin 22 (IL22), mRNA.

Price & Availability↑

CloneID	OMb01230
Clone ID Related Accession (Same CDS sequence)	NM_001194724.2 , NM_001194724.1
Accession Version	NM_001194724.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-17
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-22 precursor
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from QNVO02000060.1. On Dec 18, 2019 this sequence version replaced NM_001194724.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA4688315, SAMEA4688316 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGCCC TGCAGAAATC TGTGAGCCCT TTCCTTATGG GGACTCTGGC CACCAGCTGC 
CTCCTTCTCT TGGCCCTCTG GGTGCAGGGA GGAGCAGCTG CGCCCGTCAG CTCCCACTGC 
AGGCTTGACA AGTCCAACTT CCAGCAGCCC TATATCACCA ACCGCACCTT CATGCTGGCT 
AAGGAGGCTA GCTCGGCTGA TAACAACACA GACGTTCGTC TCATTGGGGA AAAACTGTTC 
CGCGGAGTCA GTATGAGTGA GCGCTGCTAT CTGATGAAGC AGGTGCTGAA CTTCACCCTT 
GAAGAAGTGC TGCTCCCTCA ATCGGATAGG TTCCAGCCTT ATATGCAGGA GGTGGTGCCC 
TTCCTGGCCA GGCTCAGCAA CAGTCTAAGC ACATGTCACA TTGAAGGTGA TGACCTGCAT 
ATCCAGAAGA ATGTCCAAAA GCTGAAGGAC ACAGTGAAAA AGCTTGGAGA GAGTGGAGAG 
ATCAAAGCAA TTGGAGAACT GGATTTGCTG TTTATGTCTC TGAGAAATGC CTGCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001181653.1
CDS	70..609
Translation	MAALQKSVSPFLMGTLATSCLLLLALWVQGGAAAPVSSHCRLDKSNFQQPYITNRTFMLAKEASSADNNTDVRLIGEKLFRGVSMSERCYLMKQVLNFTLEEVLLPQSDRFQPYMQEVVPFLARLSNSLSTCHIEGDDLHIQKNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI

Target ORF information:

RefSeq Version	NM_001194724.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 22 (IL22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001194724.2

ORF Insert Sequence:

ATGGCCGCCC TGCAGAAATC TGTGAGCCCT TTCCTTATGG GGACTCTGGC CACCAGCTGC 
CTCCTTCTCT TGGCCCTCTG GGTGCAGGGA GGAGCAGCTG CGCCCGTCAG CTCCCACTGC 
AGGCTTGACA AGTCCAACTT CCAGCAGCCC TATATCACCA ACCGCACCTT CATGCTGGCT 
AAGGAGGCTA GCTCGGCTGA TAACAACACA GACGTTCGTC TCATTGGGGA AAAACTGTTC 
CGCGGAGTCA GTATGAGTGA GCGCTGCTAT CTGATGAAGC AGGTGCTGAA CTTCACCCTT 
GAAGAAGTGC TGCTCCCTCA ATCGGATAGG TTCCAGCCTT ATATGCAGGA GGTGGTGCCC 
TTCCTGGCCA GGCTCAGCAA CAGTCTAAGC ACATGTCACA TTGAAGGTGA TGACCTGCAT 
ATCCAGAAGA ATGTCCAAAA GCTGAAGGAC ACAGTGAAAA AGCTTGGAGA GAGTGGAGAG 
ATCAAAGCAA TTGGAGAACT GGATTTGCTG TTTATGTCTC TGAGAAATGC CTGCATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease.
Clinical immunology (Orlando, Fla.)147(1)40-9(2013 Apr)
Xu H,Feely SL,Wang X,Liu DX,Borda JT,Dufour J,Li W,Aye PP,Doxiadis GG,Khosla C,Veazey RS,Sestak K

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
Mucosal immunology5(6)646-57(2012 Nov)
Klatt NR,Estes JD,Sun X,Ortiz AM,Barber JS,Harris LD,Cervasi B,Yokomizo LK,Pan L,Vinton CL,Tabb B,Canary LA,Dang Q,Hirsch VM,Alter G,Belkaid Y,Lifson JD,Silvestri G,Milner JD,Paiardini M,Haddad EK,Brenchley JM

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Nature biotechnology29(11)1019-23(2011 Oct)
Yan G,Zhang G,Fang X,Zhang Y,Li C,Ling F,Cooper DN,Li Q,Li Y,van Gool AJ,Du H,Chen J,Chen R,Zhang P,Huang Z,Thompson JR,Meng Y,Bai Y,Wang J,Zhuo M,Wang T,Huang Y,Wei L,Li J,Wang Z,Hu H,Yang P,Le L,Stenson PD,Li B,Liu X,Ball EV,An N,Huang Q,Zhang Y,Fan W,Zhang X,Li Y,Wang W,Katze MG,Su B,Nielsen R,Yang H,Wang J,Wang X,Wang J

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IL22 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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