Gene Symbol | IL10 |
Entrez Gene ID | 694931 |
Full Name | interleukin 10 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » IL10 cDNA ORF clone
Gene Symbol | IL10 |
Entrez Gene ID | 694931 |
Full Name | interleukin 10 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001044727.1 | NP_001038192.1 | interleukin-10 precursor |
Homo sapiens (human) | IL10 | NP_000563.1 |
Canis lupus familiaris (dog) | IL10 | NP_001003077.1 |
Mus musculus (house mouse) | Il10 | NP_034678.1 |
Rattus norvegicus (Norway rat) | Il10 | NP_036986.2 |
Xenopus tropicalis (tropical clawed frog) | il10 | NP_001165400.1 |
IL10 | NP_001038192.1 | |
Bos taurus (cattle) | IL10 | NP_776513.1 |
Gallus gallus (chicken) | IL10 | NP_001004414.2 |
Pan troglodytes (chimpanzee) | IL10 | NP_001129092.2 |
Danio rerio (zebrafish) | il10 | NP_001018621.2 |
The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection.
Mooney JP, Butler BP, Lokken KL, Xavier MN, Chau JY, Schaltenberg N, Dandekar S, George MD, Santos RL, Luckhart S, Tsolis RM
Mucosal immunology7(6)1302-11(2014 Nov)
Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection.
Pan D, Kenway-Lynch CS, Lala W, Veazey RS, Lackner AA, Das A, Pahar B
Journal of virology88(22)13015-28(2014 Nov)
Interleukin-10 prevents epithelial cell apoptosis by regulating IFN? and TNF? expression in rhesus macaque colon explants.
Pan D, Das A, Lala W, Kenway-Lynch CS, Liu DX, Veazey RS, Pahar B
Cytokine64(1)30-4(2013 Oct)
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J
Nature biotechnology29(11)1019-23(2011 Oct)
Polymorphisms in eight host genes associated with control of HIV replication do not mediate elite control of viral replication in SIV-infected Indian rhesus macaques.
Weiler A, May GE, Qi Y, Wilson N, Watkins DI
Immunogenetics58(12)1003-9(2006 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS, which may contribute to differences in the clinical presentation of NTS infection in the setting of malaria.
Title: The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection.
Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.
Title: Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection.
IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha cytokine production.
Title: Interleukin-10 prevents epithelial cell apoptosis by regulating IFN? and TNF? expression in rhesus macaque colon explants.
The following IL10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb04754 | |
Clone ID Related Accession (Same CDS sequence) | NM_001044727.1 | |
Accession Version | NM_001044727.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-10 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L26029.1. On Aug 31, 2006 this sequence version replaced XM_001085083.1. ##Evidence-Data-START## Transcript exon combination :: L26029.1, DQ890039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688325, SAMEA4688338 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCACAGCT CAGCACTGCT CTGTTGCCTA GTCCTCCTGA CTGGGGTGAG GGCCAGCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001038192.1 |
CDS | 8..544 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001044727.1 |
1 | ATGCACAGCT CAGCACTGCT CTGTTGCCTA GTCCTCCTGA CTGGGGTGAG GGCCAGCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection. |
Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection. |
Interleukin-10 prevents epithelial cell apoptosis by regulating IFN? and TNF? expression in rhesus macaque colon explants. |
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. |
Polymorphisms in eight host genes associated with control of HIV replication do not mediate elite control of viral replication in SIV-infected Indian rhesus macaques. |