Rpl11 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rpl11
Entrez Gene ID	67025
Full Name	ribosomal protein L11
Synonyms	2010203J19Rik
General protein information	Preferred Names ribosomal protein L11 Names 60S ribosomal protein L11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_025919.2	NP_080195.1	60S ribosomal protein L11
XM_006539112.3	XP_006539175.1	60S ribosomal protein L11 isoform X1
XM_006539112.2	XP_006539175.1	60S ribosomal protein L11 isoform X1
NM_025919.3	NP_080195.1	60S ribosomal protein L11

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	RpL11	NP_477054.1
Caenorhabditis elegans (roundworm)	rpl-11.1	NP_504008.1
Caenorhabditis elegans (roundworm)	rpl-11.2	NP_508413.1
Arabidopsis thaliana (thale cress)	AT5G45775	NP_568649.2
Canis lupus familiaris (dog)	RPL11	NP_001240835.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011173	XP_309477.3
Kluyveromyces lactis	KLLA0F08261g	XP_455455.1
Schizosaccharomyces pombe (fission yeast)	rpl1101	NP_594150.1
Schizosaccharomyces pombe (fission yeast)	rpl1102	NP_595899.1
Arabidopsis thaliana (thale cress)	RPL16A	NP_850376.2
Arabidopsis thaliana (thale cress)	AT3G58700	NP_191429.1
Oryza sativa (rice)	Os05g0207300	NP_001054899.1
Rattus norvegicus (Norway rat)	Rpl11	NP_001020910.1
Saccharomyces cerevisiae (baker's yeast)	RPL11A	NP_015427.1
Eremothecium gossypii	AGOS_AEL325W	NP_984535.1
Arabidopsis thaliana (thale cress)	RPL16B	NP_567563.1
Oryza sativa (rice)	Os02g0235600	NP_001046386.1
Bos taurus (cattle)	RPL11	NP_001069049.1
Mus musculus (house mouse)	Rpl11	NP_080195.1
Magnaporthe oryzae (rice blast fungus)	MGG_07753	XP_003712966.1
Neurospora crassa	NCU02509	XP_965640.2
Homo sapiens (human)	RPL11	NP_000966.2
Gallus gallus (chicken)	RPL11	NP_001026075.1
Danio rerio (zebrafish)	rpl11	NP_001002139.1
Saccharomyces cerevisiae (baker's yeast)	RPL11B	NP_011599.1
Oryza sativa (rice)	Os06g0550000	NP_001057834.2
Oryza sativa (rice)	Os01g0205500	NP_001042339.1
Xenopus tropicalis (tropical clawed frog)	rpl11	NP_001016640.1

Gene Ontology
Bibliography

Related articles in PubMed

Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis.
Kamio T, Gu BW, Olson TS, Zhang Y, Mason PJ, Bessler M
PloS one11(4)e0152263(2016)

Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.
Zhou X, Hao Q, Zhang Q, Liao JM, Ke JW, Liao P, Cao B, Lu H
Cell death and differentiation22(5)755-66(2015 May)

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.
Nott A, Nitarska J, Veenvliet JV, Schacke S, Derijck AA, Sirko P, Muchardt C, Pasterkamp RJ, Smidt MP, Riccio A
Proceedings of the National Academy of Sciences of the United States of America110(8)3113-8(2013 Feb)

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater MJ, Poortinga G, Sanij E, Hein N, Peck A, Cullinane C, Wall M, Cluse L, Drygin D, Anderes K, Huser N, Proffitt C, Bliesath J, Haddach M, Schwaebe MK, Ryckman DM, Rice WG, Schmitt C, Lowe SW, Johnstone RW, Pearson RB, McArthur GA, Hannan RD
Cancer cell22(1)51-65(2012 Jul)

Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
Morgado-Palacin L, Llanos S, Serrano M
Cell cycle (Georgetown, Tex.)11(3)503-10(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

there is a fine tuned balance in the interaction of ribosomal proteins with the MDM2/p53 axis which is important in normal hematopoiesis.
Title: Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis.

Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.
Title: Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.

The association of the L11 and Mdm2 is resulted the activation of the pathway in embryonic stem cells.
Title: Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.

The following Rpl11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rpl11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01268	NM_025919.3 Latest version!	Mus musculus ribosomal protein L11 (Rpl11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu34385	XM_006539112.3 Latest version!	Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu34385	XM_006539112.2	Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu01268	NM_025919.2	Mus musculus ribosomal protein L11 (Rpl11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rpl11 ( XM_006539112.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539175.1 Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34385
Clone ID Related Accession (Same CDS sequence)	XM_006539112.3 , XM_006539112.2
Accession Version	XM_006539112.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006539112.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCAGA GGCCGCAAGA TCAAGGGGAA AAGGAGAACC CCATGCGGGA ACTGCGCATC 
CGCAAGCTCT GCCTCAATAT CTGCGTCGGG GAGAGCGGAG ACAGACTGAC CCGGGCAGCC 
AAGGTGTTGG AGCAGCTCAC AGGCCAGACC CCGGTGTTCT CCAAAGCTAG ATACACTGTC 
AGGTCCTTTG GCATCCGGAG AAATGAGAAG ATTGCTGTTC ACTGCACAGT CCGCGGAGCC 
AAGGCAGAGG AAATTCTGGA GAAAGGCCTG AAGGTGCGGG AGTATGAGTT GCGGAAAAAT 
AACTTCTCGG ATACTGGAAA CTTTGGTTTT GGAATTCAAG AACACATTGA CCTGGGCATC 
AAATACGACC CAAGCATTGG GATCTACGGC CTGGACTTCT ATGTGGTGCT GGGTAGGCCA 
GGGTTCAGCA TCGCAGACAA GAAGCGCAGA ACAGGCTGCA TTGGGGCCAA ACACAGAATC 
AGCAAGGAGG AGGCCATGCG CTGGTTCCAG CAGAAGTACG ATGGAATCAT CCTTCCTGGA 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539175.1
CDS	337..882
Translation	MAQRPQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK

Target ORF information:

RefSeq Version	XM_006539112.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539112.2

ORF Insert Sequence:

ATGGCGCAGA GGCCGCAAGA TCAAGGGGAA AAGGAGAACC CCATGCGGGA ACTGCGCATC 
CGCAAGCTCT GCCTCAATAT CTGCGTCGGG GAGAGCGGAG ACAGACTGAC CCGGGCAGCC 
AAGGTGTTGG AGCAGCTCAC AGGCCAGACC CCGGTGTTCT CCAAAGCTAG ATACACTGTC 
AGGTCCTTTG GCATCCGGAG AAATGAGAAG ATTGCTGTTC ACTGCACAGT CCGCGGAGCC 
AAGGCAGAGG AAATTCTGGA GAAAGGCCTG AAGGTGCGGG AGTATGAGTT GCGGAAAAAT 
AACTTCTCGG ATACTGGAAA CTTTGGTTTT GGAATTCAAG AACACATTGA CCTGGGCATC 
AAATACGACC CAAGCATTGG GATCTACGGC CTGGACTTCT ATGTGGTGCT GGGTAGGCCA 
GGGTTCAGCA TCGCAGACAA GAAGCGCAGA ACAGGCTGCA TTGGGGCCAA ACACAGAATC 
AGCAAGGAGG AGGCCATGCG CTGGTTCCAG CAGAAGTACG ATGGAATCAT CCTTCCTGGA 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl11 ( NM_025919.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080195.1 Mus musculus ribosomal protein L11 (Rpl11), mRNA.

Price & Availability↑

CloneID	OMu01268
Clone ID Related Accession (Same CDS sequence)	NM_025919.2 , NM_025919.3
Accession Version	NM_025919.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK008422.1. On Apr 6, 2007 this sequence version replaced NM_025919.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK008422.1, AK013923.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCAAG ATCAAGGGGA AAAGGAGAAC CCCATGCGGG AACTGCGCAT CCGCAAGCTC 
TGCCTCAATA TCTGCGTCGG GGAGAGCGGA GACAGACTGA CCCGGGCAGC CAAGGTGTTG 
GAGCAGCTCA CAGGCCAGAC CCCGGTGTTC TCCAAAGCTA GATACACTGT CAGGTCCTTT 
GGCATCCGGA GAAATGAGAA GATTGCTGTT CACTGCACAG TCCGCGGAGC CAAGGCAGAG 
GAAATTCTGG AGAAAGGCCT GAAGGTGCGG GAGTATGAGT TGCGGAAAAA TAACTTCTCG 
GATACTGGAA ACTTTGGTTT TGGAATTCAA GAACACATTG ACCTGGGCAT CAAATACGAC 
CCAAGCATTG GGATCTACGG CCTGGACTTC TATGTGGTGC TGGGTAGGCC AGGGTTCAGC 
ATCGCAGACA AGAAGCGCAG AACAGGCTGC ATTGGGGCCA AACACAGAAT CAGCAAGGAG 
GAGGCCATGC GCTGGTTCCA GCAGAAGTAC GATGGAATCA TCCTTCCTGG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080195.1
CDS	19..555
Translation	MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK

Target ORF information:

RefSeq Version	NM_025919.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L11 (Rpl11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025919.2

ORF Insert Sequence:

ATGGCGCAAG ATCAAGGGGA AAAGGAGAAC CCCATGCGGG AACTGCGCAT CCGCAAGCTC 
TGCCTCAATA TCTGCGTCGG GGAGAGCGGA GACAGACTGA CCCGGGCAGC CAAGGTGTTG 
GAGCAGCTCA CAGGCCAGAC CCCGGTGTTC TCCAAAGCTA GATACACTGT CAGGTCCTTT 
GGCATCCGGA GAAATGAGAA GATTGCTGTT CACTGCACAG TCCGCGGAGC CAAGGCAGAG 
GAAATTCTGG AGAAAGGCCT GAAGGTGCGG GAGTATGAGT TGCGGAAAAA TAACTTCTCG 
GATACTGGAA ACTTTGGTTT TGGAATTCAA GAACACATTG ACCTGGGCAT CAAATACGAC 
CCAAGCATTG GGATCTACGG CCTGGACTTC TATGTGGTGC TGGGTAGGCC AGGGTTCAGC 
ATCGCAGACA AGAAGCGCAG AACAGGCTGC ATTGGGGCCA AACACAGAAT CAGCAAGGAG 
GAGGCCATGC GCTGGTTCCA GCAGAAGTAC GATGGAATCA TCCTTCCTGG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl11 ( NM_025919.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080195.1 Mus musculus ribosomal protein L11 (Rpl11), mRNA.

Price & Availability↑

CloneID	OMu01268
Clone ID Related Accession (Same CDS sequence)	NM_025919.2 , NM_025919.3
Accession Version	NM_025919.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L11
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX530725.11, AK008422.1, CA321948.1 and BP770399.1. On Apr 27, 2018 this sequence version replaced NM_025919.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG965960.1, BI149608.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCAAG ATCAAGGGGA AAAGGAGAAC CCCATGCGGG AACTGCGCAT CCGCAAGCTC 
TGCCTCAATA TCTGCGTCGG GGAGAGCGGA GACAGACTGA CCCGGGCAGC CAAGGTGTTG 
GAGCAGCTCA CAGGCCAGAC CCCGGTGTTC TCCAAAGCTA GATACACTGT CAGGTCCTTT 
GGCATCCGGA GAAATGAGAA GATTGCTGTT CACTGCACAG TCCGCGGAGC CAAGGCAGAG 
GAAATTCTGG AGAAAGGCCT GAAGGTGCGG GAGTATGAGT TGCGGAAAAA TAACTTCTCG 
GATACTGGAA ACTTTGGTTT TGGAATTCAA GAACACATTG ACCTGGGCAT CAAATACGAC 
CCAAGCATTG GGATCTACGG CCTGGACTTC TATGTGGTGC TGGGTAGGCC AGGGTTCAGC 
ATCGCAGACA AGAAGCGCAG AACAGGCTGC ATTGGGGCCA AACACAGAAT CAGCAAGGAG 
GAGGCCATGC GCTGGTTCCA GCAGAAGTAC GATGGAATCA TCCTTCCTGG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080195.1
CDS	41..577
Translation	MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK

Target ORF information:

RefSeq Version	NM_025919.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L11 (Rpl11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025919.3

ORF Insert Sequence:

ATGGCGCAAG ATCAAGGGGA AAAGGAGAAC CCCATGCGGG AACTGCGCAT CCGCAAGCTC 
TGCCTCAATA TCTGCGTCGG GGAGAGCGGA GACAGACTGA CCCGGGCAGC CAAGGTGTTG 
GAGCAGCTCA CAGGCCAGAC CCCGGTGTTC TCCAAAGCTA GATACACTGT CAGGTCCTTT 
GGCATCCGGA GAAATGAGAA GATTGCTGTT CACTGCACAG TCCGCGGAGC CAAGGCAGAG 
GAAATTCTGG AGAAAGGCCT GAAGGTGCGG GAGTATGAGT TGCGGAAAAA TAACTTCTCG 
GATACTGGAA ACTTTGGTTT TGGAATTCAA GAACACATTG ACCTGGGCAT CAAATACGAC 
CCAAGCATTG GGATCTACGG CCTGGACTTC TATGTGGTGC TGGGTAGGCC AGGGTTCAGC 
ATCGCAGACA AGAAGCGCAG AACAGGCTGC ATTGGGGCCA AACACAGAAT CAGCAAGGAG 
GAGGCCATGC GCTGGTTCCA GCAGAAGTAC GATGGAATCA TCCTTCCTGG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl11 ( XM_006539112.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539175.1 Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34385
Clone ID Related Accession (Same CDS sequence)	XM_006539112.3 , XM_006539112.2
Accession Version	XM_006539112.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006539112.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCAGA GGCCGCAAGA TCAAGGGGAA AAGGAGAACC CCATGCGGGA ACTGCGCATC 
CGCAAGCTCT GCCTCAATAT CTGCGTCGGG GAGAGCGGAG ACAGACTGAC CCGGGCAGCC 
AAGGTGTTGG AGCAGCTCAC AGGCCAGACC CCGGTGTTCT CCAAAGCTAG ATACACTGTC 
AGGTCCTTTG GCATCCGGAG AAATGAGAAG ATTGCTGTTC ACTGCACAGT CCGCGGAGCC 
AAGGCAGAGG AAATTCTGGA GAAAGGCCTG AAGGTGCGGG AGTATGAGTT GCGGAAAAAT 
AACTTCTCGG ATACTGGAAA CTTTGGTTTT GGAATTCAAG AACACATTGA CCTGGGCATC 
AAATACGACC CAAGCATTGG GATCTACGGC CTGGACTTCT ATGTGGTGCT GGGTAGGCCA 
GGGTTCAGCA TCGCAGACAA GAAGCGCAGA ACAGGCTGCA TTGGGGCCAA ACACAGAATC 
AGCAAGGAGG AGGCCATGCG CTGGTTCCAG CAGAAGTACG ATGGAATCAT CCTTCCTGGA 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539175.1
CDS	373..918
Translation	MAQRPQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK

Target ORF information:

RefSeq Version	XM_006539112.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L11 (Rpl11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539112.3

ORF Insert Sequence:

ATGGCGCAGA GGCCGCAAGA TCAAGGGGAA AAGGAGAACC CCATGCGGGA ACTGCGCATC 
CGCAAGCTCT GCCTCAATAT CTGCGTCGGG GAGAGCGGAG ACAGACTGAC CCGGGCAGCC 
AAGGTGTTGG AGCAGCTCAC AGGCCAGACC CCGGTGTTCT CCAAAGCTAG ATACACTGTC 
AGGTCCTTTG GCATCCGGAG AAATGAGAAG ATTGCTGTTC ACTGCACAGT CCGCGGAGCC 
AAGGCAGAGG AAATTCTGGA GAAAGGCCTG AAGGTGCGGG AGTATGAGTT GCGGAAAAAT 
AACTTCTCGG ATACTGGAAA CTTTGGTTTT GGAATTCAAG AACACATTGA CCTGGGCATC 
AAATACGACC CAAGCATTGG GATCTACGGC CTGGACTTCT ATGTGGTGCT GGGTAGGCCA 
GGGTTCAGCA TCGCAGACAA GAAGCGCAGA ACAGGCTGCA TTGGGGCCAA ACACAGAATC 
AGCAAGGAGG AGGCCATGCG CTGGTTCCAG CAGAAGTACG ATGGAATCAT CCTTCCTGGA 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis.
PloS one11(4)e0152263(2016)
Kamio T,Gu BW,Olson TS,Zhang Y,Mason PJ,Bessler M

Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition.
Cell death and differentiation22(5)755-66(2015 May)
Zhou X,Hao Q,Zhang Q,Liao JM,Ke JW,Liao P,Cao B,Lu H

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.
Proceedings of the National Academy of Sciences of the United States of America110(8)3113-8(2013 Feb)
Nott A,Nitarska J,Veenvliet JV,Schacke S,Derijck AA,Sirko P,Muchardt C,Pasterkamp RJ,Smidt MP,Riccio A

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Cancer cell22(1)51-65(2012 Jul)
Bywater MJ,Poortinga G,Sanij E,Hein N,Peck A,Cullinane C,Wall M,Cluse L,Drygin D,Anderes K,Huser N,Proffitt C,Bliesath J,Haddach M,Schwaebe MK,Ryckman DM,Rice WG,Schmitt C,Lowe SW,Johnstone RW,Pearson RB,McArthur GA,Hannan RD

Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
Cell cycle (Georgetown, Tex.)11(3)503-10(2012 Feb)
Morgado-Palacin L,Llanos S,Serrano M

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Rpl11 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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