Siglec15 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Siglec15
Entrez Gene ID	620235
Full Name	sialic acid binding Ig-like lectin 15
Synonyms	Cd33l3,EG620235,SIGLEC-I
General protein information	Preferred Names sialic acid binding Ig-like lectin 15 Names sialic acid-binding Ig-like lectin 15 CD33 molecule-like 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 E3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001101038.2	NP_001094508.1	sialic acid-binding Ig-like lectin 15 precursor
XM_011247091.3	XP_011245393.1	sialic acid-binding Ig-like lectin 15 isoform X2
XM_006526516.3	XP_006526579.1	sialic acid-binding Ig-like lectin 15 isoform X2
XM_011247091.2	XP_011245393.1	sialic acid-binding Ig-like lectin 15 isoform X3
NM_001101038.1	NP_001094508.1	sialic acid-binding Ig-like lectin 15 precursor
XM_011247092.2	XP_011245394.1	sialic acid-binding Ig-like lectin 15 isoform X4
XM_030250561.1	XP_030106421.1	sialic acid-binding Ig-like lectin 15 isoform X1
XM_006526515.3	XP_006526578.1	sialic acid-binding Ig-like lectin 15 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SIGLEC15	XP_003639220.2
Bos taurus (cattle)	SIGLEC15	NP_001179496.1
Danio rerio (zebrafish)	si:dkey-11p23.7	NP_001095865.1
Xenopus tropicalis (tropical clawed frog)	LOC101730675	XP_004911394.1
Pan troglodytes (chimpanzee)	SIGLEC15	XP_512109.2
Rattus norvegicus (Norway rat)	Siglec15	NP_001178871.1
Gallus gallus (chicken)	SIGLEC15	XP_001233766.2
Xenopus tropicalis (tropical clawed frog)	siglec15	XP_002936556.2
	SIGLEC15	XP_001089000.1
Homo sapiens (human)	SIGLEC15	NP_998767.1
Mus musculus (house mouse)	Siglec15	NP_001094508.1

Gene Ontology
Bibliography

Related articles in PubMed

Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.
Shimizu T, Takahata M, Kameda Y, Endo T, Hamano H, Hiratsuka S, Ota M, Iwasaki N
Bone7965-70(2015 Oct)

Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis.
Kameda Y, Takahata M, Mikuni S, Shimizu T, Hamano H, Angata T, Hatakeyama S, Kinjo M, Iwasaki N
Bone71217-26(2015 Feb)

Siglec-15 regulates osteoclast differentiation by modulating RANKL-induced phosphatidylinositol 3-kinase/Akt and Erk pathways in association with signaling Adaptor DAP12.
Kameda Y, Takahata M, Komatsu M, Mikuni S, Hatakeyama S, Shimizu T, Angata T, Kinjo M, Minami A, Iwasaki N
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research28(12)2463-75(2013 Dec)

Impact of docosahexaenoic acid on gene expression during osteoclastogenesis in vitro--a comprehensive analysis.
Akiyama M, Nakahama K, Morita I
Nutrients5(8)3151-62(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Siglec-15 does not mediate joint destruction in inflammatory arthritis
Title: Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.

The present findings indicate that Siglec-15 is involved in estrogen deficiency-induced differentiation of osteoclasts and is thus a potential therapeutic target for postmenopausal osteoporosis.
Title: Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis.

Siglec-15 regulates osteoclast development and bone resorption by modulating receptor activator of nuclear factor kappaB ligand (RANKL) signaling in association with DAP12.
Title: Siglec-15 regulates osteoclast differentiation by modulating RANKL-induced phosphatidylinositol 3-kinase/Akt and Erk pathways in association with signaling Adaptor DAP12.

DC-STAMP, Siglec-15, Tspan7 and Mst1r expression was downregulated by docosahexaenoic acid, but not eicosapentaenoic acid during osteoclastogenesis in vitro.
Title: Impact of docosahexaenoic acid on gene expression during osteoclastogenesis in vitro--a comprehensive analysis.

results reveal the importance of Siglec-15 in the regulation of osteoclast formation and/or function in vivo, providing new insights into osteoclast biology
Title: Impaired osteoclast differentiation and function and mild osteopetrosis development in Siglec-15-deficient mice.

The following Siglec15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Siglec15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu54971	XM_030250561.1 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu75400	XM_011247091.3 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu13056	NM_001101038.2 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OMu54971	XM_006526515.3 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OMu54972	XM_006526516.3 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OMu75401	XM_011247092.2 Latest version!	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OMu75400	XM_011247091.2	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OMu13056	NM_001101038.1	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Siglec15 ( XM_030250561.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106421.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54971
Clone ID Related Accession (Same CDS sequence)	XM_030250561.1 , XM_006526515.3
Accession Version	XM_030250561.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCTGC GCCGCGGATC GTCAACATCT CGGTGCTGCC GGGCCCCGCG 
CACGCCTTCC GCGCGCTCTG CACCGCCGAG GGGGAGCCCC CGCCCGCCCT CGCCTGGTCG 
GGTCCCGCCC CAGGCAACAG CTCCGCTGCC CTGCAGGGCC AGGGTCACGG CTACCAGGTG 
ACCGCCGAGT TGCCCGCGCT GACCCGCGAC GGCCGCTACA CGTGCACGGC GGCCAATAGC 
CTGGGCCGCG CCGAGGCCAG CGTCTACCTG TTCCGCTTCC ACGGCGCCCC CGGAACCTCG 
ACCCTAGCGC TCCTGCTGGG CGCGCTGGGC CTCAAGGCCT TGCTGCTGCT TGGCATTCTG 
GGAGCGCGTG CCACCCGACG CCGACTAGAT CACCTGGTCC CCCAGGACAC CCCTCCACGG 
TCTCAGGCTC AGGAGTCCAA TTATGAAAAT TTGAGCCAGA TGAGTCCTCC AGGCCACCAG 
CTGCCACGTG TTTGCTGTGA GGAACTCCTC AGCCATCACC ATCTAGTCAT TCACCATGAG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106421.1
CDS	143..1168
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	XM_030250561.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250561.1

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCTGC GCCGCGGATC GTCAACATCT CGGTGCTGCC GGGCCCCGCG 
CACGCCTTCC GCGCGCTCTG CACCGCCGAG GGGGAGCCCC CGCCCGCCCT CGCCTGGTCG 
GGTCCCGCCC CAGGCAACAG CTCCGCTGCC CTGCAGGGCC AGGGTCACGG CTACCAGGTG 
ACCGCCGAGT TGCCCGCGCT GACCCGCGAC GGCCGCTACA CGTGCACGGC GGCCAATAGC 
CTGGGCCGCG CCGAGGCCAG CGTCTACCTG TTCCGCTTCC ACGGCGCCCC CGGAACCTCG 
ACCCTAGCGC TCCTGCTGGG CGCGCTGGGC CTCAAGGCCT TGCTGCTGCT TGGCATTCTG 
GGAGCGCGTG CCACCCGACG CCGACTAGAT CACCTGGTCC CCCAGGACAC CCCTCCACGG 
TCTCAGGCTC AGGAGTCCAA TTATGAAAAT TTGAGCCAGA TGAGTCCTCC AGGCCACCAG 
CTGCCACGTG TTTGCTGTGA GGAACTCCTC AGCCATCACC ATCTAGTCAT TCACCATGAG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( XM_011247091.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245393.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu75400
Clone ID Related Accession (Same CDS sequence)	XM_011247091.3 , XM_011247091.2
Accession Version	XM_011247091.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011247091.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GGTCTCAGGC TCAGGAGTCC AATTATGAAA 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245393.1
CDS	144..1049
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLGLRLRSPIMKI

Target ORF information:

RefSeq Version	XM_011247091.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247091.3

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GGTCTCAGGC TCAGGAGTCC AATTATGAAA 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( NM_001101038.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001094508.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.

Price & Availability↑

CloneID	OMu13056
Clone ID Related Accession (Same CDS sequence)	NM_001101038.2 , NM_001101038.1
Accession Version	NM_001101038.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-13
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC126553.4. On Feb 20, 2019 this sequence version replaced NM_001101038.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY971517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GATCACCTGG TCCCCCAGGA CACCCCTCCA 
CGGTCTCAGG CTCAGGAGTC CAATTATGAA AATTTGAGCC AGATGAGTCC TCCAGGCCAC 
CAGCTGCCAC GTGTTTGCTG TGAGGAACTC CTCAGCCATC ACCATCTAGT CATTCACCAT 
GAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094508.1
CDS	174..1202
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	NM_001101038.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001101038.2

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GATCACCTGG TCCCCCAGGA CACCCCTCCA 
CGGTCTCAGG CTCAGGAGTC CAATTATGAA AATTTGAGCC AGATGAGTCC TCCAGGCCAC 
CAGCTGCCAC GTGTTTGCTG TGAGGAACTC CTCAGCCATC ACCATCTAGT CATTCACCAT 
GAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( NM_001101038.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001094508.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.

Price & Availability↑

CloneID	OMu13056
Clone ID Related Accession (Same CDS sequence)	NM_001101038.2 , NM_001101038.1
Accession Version	NM_001101038.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY971517.1. On or before Aug 14, 2007 this sequence version replaced XM_916291.3, XM_884636.3. ##Evidence-Data-START## Transcript exon combination :: AY971517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GATCACCTGG TCCCCCAGGA CACCCCTCCA 
CGGTCTCAGG CTCAGGAGTC CAATTATGAA AATTTGAGCC AGATGAGTCC TCCAGGCCAC 
CAGCTGCCAC GTGTTTGCTG TGAGGAACTC CTCAGCCATC ACCATCTAGT CATTCACCAT 
GAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094508.1
CDS	1..1029
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	NM_001101038.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001101038.1

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GATCACCTGG TCCCCCAGGA CACCCCTCCA 
CGGTCTCAGG CTCAGGAGTC CAATTATGAA AATTTGAGCC AGATGAGTCC TCCAGGCCAC 
CAGCTGCCAC GTGTTTGCTG TGAGGAACTC CTCAGCCATC ACCATCTAGT CATTCACCAT 
GAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( XM_006526515.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526578.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54971
Clone ID Related Accession (Same CDS sequence)	XM_030250561.1 , XM_006526515.3
Accession Version	XM_006526515.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526515.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCTGC GCCGCGGATC GTCAACATCT CGGTGCTGCC GGGCCCCGCG 
CACGCCTTCC GCGCGCTCTG CACCGCCGAG GGGGAGCCCC CGCCCGCCCT CGCCTGGTCG 
GGTCCCGCCC CAGGCAACAG CTCCGCTGCC CTGCAGGGCC AGGGTCACGG CTACCAGGTG 
ACCGCCGAGT TGCCCGCGCT GACCCGCGAC GGCCGCTACA CGTGCACGGC GGCCAATAGC 
CTGGGCCGCG CCGAGGCCAG CGTCTACCTG TTCCGCTTCC ACGGCGCCCC CGGAACCTCG 
ACCCTAGCGC TCCTGCTGGG CGCGCTGGGC CTCAAGGCCT TGCTGCTGCT TGGCATTCTG 
GGAGCGCGTG CCACCCGACG CCGACTAGAT CACCTGGTCC CCCAGGACAC CCCTCCACGG 
TCTCAGGCTC AGGAGTCCAA TTATGAAAAT TTGAGCCAGA TGAGTCCTCC AGGCCACCAG 
CTGCCACGTG TTTGCTGTGA GGAACTCCTC AGCCATCACC ATCTAGTCAT TCACCATGAG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526578.1
CDS	169..1194
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	XM_006526515.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526515.3

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCTGC GCCGCGGATC GTCAACATCT CGGTGCTGCC GGGCCCCGCG 
CACGCCTTCC GCGCGCTCTG CACCGCCGAG GGGGAGCCCC CGCCCGCCCT CGCCTGGTCG 
GGTCCCGCCC CAGGCAACAG CTCCGCTGCC CTGCAGGGCC AGGGTCACGG CTACCAGGTG 
ACCGCCGAGT TGCCCGCGCT GACCCGCGAC GGCCGCTACA CGTGCACGGC GGCCAATAGC 
CTGGGCCGCG CCGAGGCCAG CGTCTACCTG TTCCGCTTCC ACGGCGCCCC CGGAACCTCG 
ACCCTAGCGC TCCTGCTGGG CGCGCTGGGC CTCAAGGCCT TGCTGCTGCT TGGCATTCTG 
GGAGCGCGTG CCACCCGACG CCGACTAGAT CACCTGGTCC CCCAGGACAC CCCTCCACGG 
TCTCAGGCTC AGGAGTCCAA TTATGAAAAT TTGAGCCAGA TGAGTCCTCC AGGCCACCAG 
CTGCCACGTG TTTGCTGTGA GGAACTCCTC AGCCATCACC ATCTAGTCAT TCACCATGAG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( XM_006526516.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526579.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54972
Clone ID Related Accession (Same CDS sequence)	XM_006526516.3
Accession Version	XM_006526516.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526516.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTAAGTC TGATGTGTCT CTGGCCCGCA GGTGCCCCGG CGCAGCGCTG GTCCATGCAG 
GTGCCCGCGG AGGTGAACGC GGAGGCTGGC GACGCGGCGG TGCTGCCCTG CACCTTCACG 
CACCCGCACC GCCACTACGA CGGGCCGCTG ACGGCCATCT GGCGCTCGGG CGAGCCGTAC 
GCGGGCCCGC AGGTGTTCCG CTGCACCGCG GCGCCGGGCA GCGAGCTGTG CCAGACGGCG 
CTGAGCCTGC ACGGCCGCTT CCGCCTGCTG GGCAACCCGC GCCGCAACGA CCTGTCCCTG 
CGCGTCGAGC GCCTCGCCCT GGCGGACAGC GGCCGCTACT TCTGCCGCGT GGAGTTCACC 
GGCGACGCCC ACGATCGCTA TGAGAGTCGC CATGGGGTCC GTCTGCGCGT GACTGCAGCT 
GCGCCGCGGA TCGTCAACAT CTCGGTGCTG CCGGGCCCCG CGCACGCCTT CCGCGCGCTC 
TGCACCGCCG AGGGGGAGCC CCCGCCCGCC CTCGCCTGGT CGGGTCCCGC CCCAGGCAAC 
AGCTCCGCTG CCCTGCAGGG CCAGGGTCAC GGCTACCAGG TGACCGCCGA GTTGCCCGCG 
CTGACCCGCG ACGGCCGCTA CACGTGCACG GCGGCCAATA GCCTGGGCCG CGCCGAGGCC 
AGCGTCTACC TGTTCCGCTT CCACGGCGCC CCCGGAACCT CGACCCTAGC GCTCCTGCTG 
GGCGCGCTGG GCCTCAAGGC CTTGCTGCTG CTTGGCATTC TGGGAGCGCG TGCCACCCGA 
CGCCGACTAG ATCACCTGGT CCCCCAGGAC ACCCCTCCAC GGTCTCAGGC TCAGGAGTCC 
AATTATGAAA ATTTGAGCCA GATGAGTCCT CCAGGCCACC AGCTGCCACG TGTTTGCTGT 
GAGGAACTCC TCAGCCATCA CCATCTAGTC ATTCACCATG AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526579.1
CDS	305..1252
Translation	MLSLMCLWPAGAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	XM_006526516.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526516.3

ORF Insert Sequence:

ATGCTAAGTC TGATGTGTCT CTGGCCCGCA GGTGCCCCGG CGCAGCGCTG GTCCATGCAG 
GTGCCCGCGG AGGTGAACGC GGAGGCTGGC GACGCGGCGG TGCTGCCCTG CACCTTCACG 
CACCCGCACC GCCACTACGA CGGGCCGCTG ACGGCCATCT GGCGCTCGGG CGAGCCGTAC 
GCGGGCCCGC AGGTGTTCCG CTGCACCGCG GCGCCGGGCA GCGAGCTGTG CCAGACGGCG 
CTGAGCCTGC ACGGCCGCTT CCGCCTGCTG GGCAACCCGC GCCGCAACGA CCTGTCCCTG 
CGCGTCGAGC GCCTCGCCCT GGCGGACAGC GGCCGCTACT TCTGCCGCGT GGAGTTCACC 
GGCGACGCCC ACGATCGCTA TGAGAGTCGC CATGGGGTCC GTCTGCGCGT GACTGCAGCT 
GCGCCGCGGA TCGTCAACAT CTCGGTGCTG CCGGGCCCCG CGCACGCCTT CCGCGCGCTC 
TGCACCGCCG AGGGGGAGCC CCCGCCCGCC CTCGCCTGGT CGGGTCCCGC CCCAGGCAAC 
AGCTCCGCTG CCCTGCAGGG CCAGGGTCAC GGCTACCAGG TGACCGCCGA GTTGCCCGCG 
CTGACCCGCG ACGGCCGCTA CACGTGCACG GCGGCCAATA GCCTGGGCCG CGCCGAGGCC 
AGCGTCTACC TGTTCCGCTT CCACGGCGCC CCCGGAACCT CGACCCTAGC GCTCCTGCTG 
GGCGCGCTGG GCCTCAAGGC CTTGCTGCTG CTTGGCATTC TGGGAGCGCG TGCCACCCGA 
CGCCGACTAG ATCACCTGGT CCCCCAGGAC ACCCCTCCAC GGTCTCAGGC TCAGGAGTCC 
AATTATGAAA ATTTGAGCCA GATGAGTCCT CCAGGCCACC AGCTGCCACG TGTTTGCTGT 
GAGGAACTCC TCAGCCATCA CCATCTAGTC ATTCACCATG AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( XM_011247091.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245393.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu75400
Clone ID Related Accession (Same CDS sequence)	XM_011247091.3 , XM_011247091.2
Accession Version	XM_011247091.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247091.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GGTCTCAGGC TCAGGAGTCC AATTATGAAA 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245393.1
CDS	170..1075
Translation	MEGSLQLLACLACVLQMGSLVKTRRDASGDLLNTEAHSAPAQRWSMQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLGLRLRSPIMKI

Target ORF information:

RefSeq Version	XM_011247091.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247091.2

ORF Insert Sequence:

ATGGAGGGGT CCCTCCAACT CCTGGCCTGC TTGGCCTGTG TGCTCCAGAT GGGATCCCTT 
GTGAAAACTA GAAGAGACGC TTCGGGGGAT CTGCTCAACA CAGAGGCGCA CAGTGCCCCG 
GCGCAGCGCT GGTCCATGCA GGTGCCCGCG GAGGTGAACG CGGAGGCTGG CGACGCGGCG 
GTGCTGCCCT GCACCTTCAC GCACCCGCAC CGCCACTACG ACGGGCCGCT GACGGCCATC 
TGGCGCTCGG GCGAGCCGTA CGCGGGCCCG CAGGTGTTCC GCTGCACCGC GGCGCCGGGC 
AGCGAGCTGT GCCAGACGGC GCTGAGCCTG CACGGCCGCT TCCGCCTGCT GGGCAACCCG 
CGCCGCAACG ACCTGTCCCT GCGCGTCGAG CGCCTCGCCC TGGCGGACAG CGGCCGCTAC 
TTCTGCCGCG TGGAGTTCAC CGGCGACGCC CACGATCGCT ATGAGAGTCG CCATGGGGTC 
CGTCTGCGCG TGACTGCAGC TGCGCCGCGG ATCGTCAACA TCTCGGTGCT GCCGGGCCCC 
GCGCACGCCT TCCGCGCGCT CTGCACCGCC GAGGGGGAGC CCCCGCCCGC CCTCGCCTGG 
TCGGGTCCCG CCCCAGGCAA CAGCTCCGCT GCCCTGCAGG GCCAGGGTCA CGGCTACCAG 
GTGACCGCCG AGTTGCCCGC GCTGACCCGC GACGGCCGCT ACACGTGCAC GGCGGCCAAT 
AGCCTGGGCC GCGCCGAGGC CAGCGTCTAC CTGTTCCGCT TCCACGGCGC CCCCGGAACC 
TCGACCCTAG CGCTCCTGCT GGGCGCGCTG GGCCTCAAGG CCTTGCTGCT GCTTGGCATT 
CTGGGAGCGC GTGCCACCCG ACGCCGACTA GGTCTCAGGC TCAGGAGTCC AATTATGAAA 
ATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Siglec15 ( XM_011247092.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245394.1 Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OMu75401
Clone ID Related Accession (Same CDS sequence)	XM_011247092.2
Accession Version	XM_011247092.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	sialic acid-binding Ig-like lectin 15 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247092.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGTGC CCGCGGAGGT GAACGCGGAG GCTGGCGACG CGGCGGTGCT GCCCTGCACC 
TTCACGCACC CGCACCGCCA CTACGACGGG CCGCTGACGG CCATCTGGCG CTCGGGCGAG 
CCGTACGCGG GCCCGCAGGT GTTCCGCTGC ACCGCGGCGC CGGGCAGCGA GCTGTGCCAG 
ACGGCGCTGA GCCTGCACGG CCGCTTCCGC CTGCTGGGCA ACCCGCGCCG CAACGACCTG 
TCCCTGCGCG TCGAGCGCCT CGCCCTGGCG GACAGCGGCC GCTACTTCTG CCGCGTGGAG 
TTCACCGGCG ACGCCCACGA TCGCTATGAG AGTCGCCATG GGGTCCGTCT GCGCGTGACT 
GCAGCTGCGC CGCGGATCGT CAACATCTCG GTGCTGCCGG GCCCCGCGCA CGCCTTCCGC 
GCGCTCTGCA CCGCCGAGGG GGAGCCCCCG CCCGCCCTCG CCTGGTCGGG TCCCGCCCCA 
GGCAACAGCT CCGCTGCCCT GCAGGGCCAG GGTCACGGCT ACCAGGTGAC CGCCGAGTTG 
CCCGCGCTGA CCCGCGACGG CCGCTACACG TGCACGGCGG CCAATAGCCT GGGCCGCGCC 
GAGGCCAGCG TCTACCTGTT CCGCTTCCAC GGCGCCCCCG GAACCTCGAC CCTAGCGCTC 
CTGCTGGGCG CGCTGGGCCT CAAGGCCTTG CTGCTGCTTG GCATTCTGGG AGCGCGTGCC 
ACCCGACGCC GACTAGATCA CCTGGTCCCC CAGGACACCC CTCCACGGTC TCAGGCTCAG 
GAGTCCAATT ATGAAAATTT GAGCCAGATG AGTCCTCCAG GCCACCAGCT GCCACGTGTT 
TGCTGTGAGG AACTCCTCAG CCATCACCAT CTAGTCATTC ACCATGAGAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245394.1
CDS	280..1173
Translation	MQVPAEVNAEAGDAAVLPCTFTHPHRHYDGPLTAIWRSGEPYAGPQVFRCTAAPGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADSGRYFCRVEFTGDAHDRYESRHGVRLRVTAAAPRIVNISVLPGPAHAFRALCTAEGEPPPALAWSGPAPGNSSAALQGQGHGYQVTAELPALTRDGRYTCTAANSLGRAEASVYLFRFHGAPGTSTLALLLGALGLKALLLLGILGARATRRRLDHLVPQDTPPRSQAQESNYENLSQMSPPGHQLPRVCCEELLSHHHLVIHHEK

Target ORF information:

RefSeq Version	XM_011247092.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sialic acid binding Ig-like lectin 15 (Siglec15), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247092.2

ORF Insert Sequence:

ATGCAGGTGC CCGCGGAGGT GAACGCGGAG GCTGGCGACG CGGCGGTGCT GCCCTGCACC 
TTCACGCACC CGCACCGCCA CTACGACGGG CCGCTGACGG CCATCTGGCG CTCGGGCGAG 
CCGTACGCGG GCCCGCAGGT GTTCCGCTGC ACCGCGGCGC CGGGCAGCGA GCTGTGCCAG 
ACGGCGCTGA GCCTGCACGG CCGCTTCCGC CTGCTGGGCA ACCCGCGCCG CAACGACCTG 
TCCCTGCGCG TCGAGCGCCT CGCCCTGGCG GACAGCGGCC GCTACTTCTG CCGCGTGGAG 
TTCACCGGCG ACGCCCACGA TCGCTATGAG AGTCGCCATG GGGTCCGTCT GCGCGTGACT 
GCAGCTGCGC CGCGGATCGT CAACATCTCG GTGCTGCCGG GCCCCGCGCA CGCCTTCCGC 
GCGCTCTGCA CCGCCGAGGG GGAGCCCCCG CCCGCCCTCG CCTGGTCGGG TCCCGCCCCA 
GGCAACAGCT CCGCTGCCCT GCAGGGCCAG GGTCACGGCT ACCAGGTGAC CGCCGAGTTG 
CCCGCGCTGA CCCGCGACGG CCGCTACACG TGCACGGCGG CCAATAGCCT GGGCCGCGCC 
GAGGCCAGCG TCTACCTGTT CCGCTTCCAC GGCGCCCCCG GAACCTCGAC CCTAGCGCTC 
CTGCTGGGCG CGCTGGGCCT CAAGGCCTTG CTGCTGCTTG GCATTCTGGG AGCGCGTGCC 
ACCCGACGCC GACTAGATCA CCTGGTCCCC CAGGACACCC CTCCACGGTC TCAGGCTCAG 
GAGTCCAATT ATGAAAATTT GAGCCAGATG AGTCCTCCAG GCCACCAGCT GCCACGTGTT 
TGCTGTGAGG AACTCCTCAG CCATCACCAT CTAGTCATTC ACCATGAGAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.
Bone7965-70(2015 Oct)
Shimizu T,Takahata M,Kameda Y,Endo T,Hamano H,Hiratsuka S,Ota M,Iwasaki N

Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis.
Bone71217-26(2015 Feb)
Kameda Y,Takahata M,Mikuni S,Shimizu T,Hamano H,Angata T,Hatakeyama S,Kinjo M,Iwasaki N

Siglec-15 regulates osteoclast differentiation by modulating RANKL-induced phosphatidylinositol 3-kinase/Akt and Erk pathways in association with signaling Adaptor DAP12.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research28(12)2463-75(2013 Dec)
Kameda Y,Takahata M,Komatsu M,Mikuni S,Hatakeyama S,Shimizu T,Angata T,Kinjo M,Minami A,Iwasaki N

Impact of docosahexaenoic acid on gene expression during osteoclastogenesis in vitro--a comprehensive analysis.
Nutrients5(8)3151-62(2013 Aug)
Akiyama M,Nakahama K,Morita I

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Siglec15 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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