RNF11 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	RNF11
Entrez Gene ID	29864
Full Name	ring finger protein 11
General protein information	Preferred Names ring finger protein 11 Names RING finger protein 11 NEDD4 WW domain-binding protein 2 sid 1669
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 4 Map Location: 4\|4 C7

mRNA and Protein(s)

mRNA	Protein	Name
NM_013876.3	NP_038904.1	RING finger protein 11
XM_011240549.1	XP_011238851.1	RING finger protein 11 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RNF11	NP_001238877.1
Danio rerio (zebrafish)	rnf11b	NP_001121880.1
Drosophila melanogaster (fruit fly)	CG32850	NP_001259053.1
Xenopus tropicalis (tropical clawed frog)	rnf11	NP_001016437.1
Homo sapiens (human)	RNF11	NP_055187.1
Caenorhabditis elegans (roundworm)	CELE_C01G6.4	NP_495976.1
Bos taurus (cattle)	RNF11	NP_001071421.1
Mus musculus (house mouse)	Rnf11	NP_038904.1
Rattus norvegicus (Norway rat)	Rnf11l1	NP_001258153.1
	RNF11	XP_001111014.1
Gallus gallus (chicken)	RNF11	NP_001006540.1

Gene Ontology
Bibliography

Related articles in PubMed

Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search.
Sun H, Hunter T
The Journal of biological chemistry287(50)42071-83(2012 Dec)

RNF11 modulates microglia activation through NF-?B signalling cascade.
Dalal NV, Pranski EL, Tansey MG, Lah JJ, Levey AI, Betarbet RS
Neuroscience letters528(2)174-9(2012 Oct)

The kinase IKK? inhibits activation of the transcription factor NF-?B by phosphorylating the regulatory molecule TAX1BP1.
Shembade N, Pujari R, Harhaj NS, Abbott DW, Harhaj EW
Nature immunology12(9)834-43(2011 Jul)

Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Rorick NK, Kinoshita A, Weirather JL, Peyrard-Janvid M, de Lima RL, Dunnwald M, Shanske AL, Moretti-Ferreira D, Koillinen H, Kere J, Mansilla MA, Murray JC, Goudy SL, Schutte BC
American journal of medical genetics. Part A155A(6)1314-21(2011 Jun)

Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.
Dumitriu B, Bhattaram P, Dy P, Huang Y, Quayum N, Jensen J, Lefebvre V
PloS one5(8)e12088(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Microglial RNF11 is a negative regulator of NF-kappaB signalling pathway and could be a strong potential target for modulating inflammatory responses in neurodegenerative diseases.
Title: RNF11 modulates microglia activation through NF-?B signalling cascade.

The following RNF11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNF11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10101	NM_013876.3 Latest version!	Mus musculus ring finger protein 11 (Rnf11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu10101	XM_011240549.1 Latest version!	Mus musculus ring finger protein 11 (Rnf11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RNF11 ( NM_013876.3 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_038904.1 Mus musculus ring finger protein 11 (Rnf11), mRNA.

Price & Availability↑

CloneID	OMu10101
Clone ID Related Accession (Same CDS sequence)	NM_013876.3 , XM_011240549.1
Accession Version	NM_013876.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	RING finger protein 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL669905.14. On Mar 21, 2007 this sequence version replaced NM_013876.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC010299.1, AK014254.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAACT GCCTCAAATC CCCGACTTCG GATGACATCT CCCTGCTTCA CGAGTCTCAG 
TCCGACCGGG CTAGCTTTGG CGAGGGGACG GAGCCAGATC AGGAGCCGCC GCCGCCATAT 
CAGGAACAAG TTCCTGTTCC CATCTATCAT CCGACACCTA GCCAGACTCG GCTAGCAACT 
CAGCTGACTG AAGAGGAACA AATTAGAATA GCTCAAAGAA TAGGCCTTAT ACAGCATCTG 
CCTAAAGGAG TTTATGACCC TGGAAGAGAT GGATCAGAAA AAAAGATCCG AGAGTGTGTG 
ATCTGTATGA TGGACTTTGT TTATGGGGAC CCAATTCGAT TTCTGCCGTG CATGCACATC 
TATCACCTGG ACTGTATAGA TGACTGGTTG ATGAGATCCT TCACGTGCCC CTCCTGCATG 
GAGCCAGTGG ATGCAGCACT GCTTTCATCC TATGAGACTA ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038904.1
CDS	274..738
Translation	MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPIYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN

Target ORF information:

RefSeq Version	NM_013876.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ring finger protein 11 (Rnf11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013876.3

ORF Insert Sequence:

ATGGGGAACT GCCTCAAATC CCCGACTTCG GATGACATCT CCCTGCTTCA CGAGTCTCAG 
TCCGACCGGG CTAGCTTTGG CGAGGGGACG GAGCCAGATC AGGAGCCGCC GCCGCCATAT 
CAGGAACAAG TTCCTGTTCC CATCTATCAT CCGACACCTA GCCAGACTCG GCTAGCAACT 
CAGCTGACTG AAGAGGAACA AATTAGAATA GCTCAAAGAA TAGGCCTTAT ACAGCATCTG 
CCTAAAGGAG TTTATGACCC TGGAAGAGAT GGATCAGAAA AAAAGATCCG AGAGTGTGTG 
ATCTGTATGA TGGACTTTGT TTATGGGGAC CCAATTCGAT TTCTGCCGTG CATGCACATC 
TATCACCTGG ACTGTATAGA TGACTGGTTG ATGAGATCCT TCACGTGCCC CTCCTGCATG 
GAGCCAGTGG ATGCAGCACT GCTTTCATCC TATGAGACTA ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RNF11 ( XM_011240549.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_011238851.1 Mus musculus ring finger protein 11 (Rnf11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10101
Clone ID Related Accession (Same CDS sequence)	NM_013876.3 , XM_011240549.1
Accession Version	XM_011240549.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	RING finger protein 11 isoform X1
Comment

ATGGGGAACT GCCTCAAATC CCCGACTTCG GATGACATCT CCCTGCTTCA CGAGTCTCAG 
TCCGACCGGG CTAGCTTTGG CGAGGGGACG GAGCCAGATC AGGAGCCGCC GCCGCCATAT 
CAGGAACAAG TTCCTGTTCC CATCTATCAT CCGACACCTA GCCAGACTCG GCTAGCAACT 
CAGCTGACTG AAGAGGAACA AATTAGAATA GCTCAAAGAA TAGGCCTTAT ACAGCATCTG 
CCTAAAGGAG TTTATGACCC TGGAAGAGAT GGATCAGAAA AAAAGATCCG AGAGTGTGTG 
ATCTGTATGA TGGACTTTGT TTATGGGGAC CCAATTCGAT TTCTGCCGTG CATGCACATC 
TATCACCTGG ACTGTATAGA TGACTGGTTG ATGAGATCCT TCACGTGCCC CTCCTGCATG 
GAGCCAGTGG ATGCAGCACT GCTTTCATCC TATGAGACTA ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011238851.1
Translation	MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPIYHPTPSQTRLATQLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHIYHLDCIDDWLMRSFTCPSCMEPVDAALLSSYETN

Target ORF information:

RefSeq Version	XM_011240549.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus ring finger protein 11 (Rnf11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240549.1

ORF Insert Sequence:

ATGGGGAACT GCCTCAAATC CCCGACTTCG GATGACATCT CCCTGCTTCA CGAGTCTCAG 
TCCGACCGGG CTAGCTTTGG CGAGGGGACG GAGCCAGATC AGGAGCCGCC GCCGCCATAT 
CAGGAACAAG TTCCTGTTCC CATCTATCAT CCGACACCTA GCCAGACTCG GCTAGCAACT 
CAGCTGACTG AAGAGGAACA AATTAGAATA GCTCAAAGAA TAGGCCTTAT ACAGCATCTG 
CCTAAAGGAG TTTATGACCC TGGAAGAGAT GGATCAGAAA AAAAGATCCG AGAGTGTGTG 
ATCTGTATGA TGGACTTTGT TTATGGGGAC CCAATTCGAT TTCTGCCGTG CATGCACATC 
TATCACCTGG ACTGTATAGA TGACTGGTTG ATGAGATCCT TCACGTGCCC CTCCTGCATG 
GAGCCAGTGG ATGCAGCACT GCTTTCATCC TATGAGACTA ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search.
The Journal of biological chemistry287(50)42071-83(2012 Dec)
Sun H,Hunter T

RNF11 modulates microglia activation through NF-?B signalling cascade.
Neuroscience letters528(2)174-9(2012 Oct)
Dalal NV,Pranski EL,Tansey MG,Lah JJ,Levey AI,Betarbet RS

The kinase IKK? inhibits activation of the transcription factor NF-?B by phosphorylating the regulatory molecule TAX1BP1.
Nature immunology12(9)834-43(2011 Jul)
Shembade N,Pujari R,Harhaj NS,Abbott DW,Harhaj EW

Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
American journal of medical genetics. Part A155A(6)1314-21(2011 Jun)
Rorick NK,Kinoshita A,Weirather JL,Peyrard-Janvid M,de Lima RL,Dunnwald M,Shanske AL,Moretti-Ferreira D,Koillinen H,Kere J,Mansilla MA,Murray JC,Goudy SL,Schutte BC

Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.
PloS one5(8)e12088(2010 Aug)
Dumitriu B,Bhattaram P,Dy P,Huang Y,Quayum N,Jensen J,Lefebvre V

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RNF11 cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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