gRNAs
The following Flnb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Flnb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu49318 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006518050.1 , XM_006518050.2 | |
| Accession Version | XM_006518050.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7737bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | filamin-B isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006518050.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006518113.1 |
| CDS | 232..7968 |
| Translation |
Target ORF information:
Target ORF information:
|
 XM_006518050.2 |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu16918 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001081427.1 | |
| Accession Version | NM_001081427.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7809bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | filamin-B isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ112968.1, AK050046.1, BP765788.1, CD555839.1, BY101832.1, BP753071.1, BU055777.1, CV558093.1, AC140322.4, CD549389.1, CD546916.1, CF165547.1, BU703688.1, CN534523.1, BG076906.2, CF166040.1, CF536812.1, CB290081.1, CF898917.1, CA749811.1, DV653075.1, AA272439.1, DV653022.1 and BP753829.1. On Mar 12, 2014 this sequence version replaced XM_006518049.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). This gene lacks full-length transcript support, and therefore the exon combination of this variant is inferred based on tiled partial transcripts and full-length orthologous alignments, e.g., human AF043045.1. CCDS Note: The exon combination of this CCDS representation is inferred due to a lack of full-length transcript support for this gene. It is supported by tiled partial transcripts and full-length orthologous alignments (e.g., human AF043045.1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001074896.1 |
| CDS | 196..8004 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001081427.1 |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu20927 | |
| Clone ID Related Accession (Same CDS sequence) | NM_134080.1 | |
| Accession Version | NM_134080.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7776bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Mus musculus(house mouse) | |
| Product | filamin-B isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ112968.1, AK050046.1, BP765788.1, CD555839.1, AC140322.4, BY101832.1, BU055777.1, CV558093.1, CD549389.1, CD546916.1, CF165547.1, BU703688.1, CN534523.1, BG076906.2, CF166040.1, CF736029.1, CB290081.1, BM950536.1, CF551577.1, BM949278.1, CF172628.1, CA537344.1, CB194973.1 and BP753072.1. On or before Jul 25, 2007 this sequence version replaced XM_001471989.1, XM_001472027.1, XM_904364.3, XM_001478129.1, XM_001478141.1, XM_990154.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. This gene lacks full-length transcript support, and therefore the exon combination of this variant is inferred based on tiled partial transcripts and full-length orthologous alignments, e.g., human AB191258.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_598841.1 |
| CDS | 196..7971 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_134080.1 |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu49318 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006518050.1 , XM_006518050.2 | |
| Accession Version | XM_006518050.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7737bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | filamin-B isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006518113.1 |
| CDS | 191..7927 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006518050.1 |
1 | ATGCCGGTGA CGGAGAAAGA CCTGGCGGAG GACGCGCCGT GGAAGAAGAT TCAGCAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. |
Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. |
Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. |
Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. |
