Abce1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abce1
Entrez Gene ID	24015
Full Name	ATP-binding cassette, sub-family E (OABP), member 1
Synonyms	C79080,Oabp,RLI,RNS41,RNS4I,Rnaseli
General protein information	Preferred Names ATP-binding cassette, sub-family E (OABP), member 1 Names ATP-binding cassette sub-family E member 1 ATP-binding cassette, subfamily E, member 1 RNS4l (Eye) RNase L inhibitor ribonuclease 4 inhibitor ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C1
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_015751.2	NP_056566.2	ATP-binding cassette sub-family E member 1

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_AGR125W	NP_986791.1
Drosophila melanogaster (fruit fly)	pix	NP_729435.1
Magnaporthe oryzae (rice blast fungus)	MGG_11382	XP_003713614.1
	ABCE1	XP_001095781.1
Mus musculus (house mouse)	Abce1	NP_056566.2
Gallus gallus (chicken)	ABCE1	NP_001006440.1
Kluyveromyces lactis	KLLA0C17556g	XP_452984.1
Schizosaccharomyces pombe (fission yeast)	rli1	NP_596732.1
Arabidopsis thaliana (thale cress)	RLI2	NP_193656.2
Canis lupus familiaris (dog)	ABCE1	XP_867212.2
Rattus norvegicus (Norway rat)	Abce1	NP_001101916.1
Danio rerio (zebrafish)	abce1	NP_998216.2
Caenorhabditis elegans (roundworm)	abce-1	NP_499717.1
Oryza sativa (rice)	Os11g0546000	NP_001068062.1
Xenopus tropicalis (tropical clawed frog)	abce1	NP_001005628.1
Homo sapiens (human)	ABCE1	NP_001035809.1
Pan troglodytes (chimpanzee)	ABCE1	NP_001233538.1
Bos taurus (cattle)	ABCE1	NP_001077154.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002182	XP_308004.3
Saccharomyces cerevisiae (baker's yeast)	RLI1	NP_010376.3
Neurospora crassa	NCU03061	XP_963869.2

Gene Ontology
Bibliography

Related articles in PubMed

Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte.
Jiao XF, Huang CJ, Wu D, Zhang JY, Long YT, Chen F, Li X, Huo LJ
Oncotarget8(24)39012-39020(2017 Jun)

Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons.
Sugiyama C, Kuramoto N, Nagashima R, Yoneyama M, Ogita K
Neurochemistry international53(3-4)71-8(2008 Sep)

Transcription profile during maternal to zygotic transition in the mouse embryo.
Li XY, Cui XS, Kim NH
Reproduction, fertility, and development18(6)635-45(2006)

Oligosyndactylism mice have an inversion of chromosome 8.
Wise TL, Pravtcheva DD
Genetics168(4)2099-112(2004 Dec)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of RNase L is a signal generated by NMDA receptor in cortical neurons. RNase L expression and RNA degradation may be events that cause neuronal damage induced by NMDA receptor activation.
Title: Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons.

The following Abce1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abce1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10214	NM_015751.2 Latest version!	Mus musculus ATP-binding cassette, sub-family E (OABP), member 1 (Abce1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abce1 ( NM_015751.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056566.2 Mus musculus ATP-binding cassette, sub-family E (OABP), member 1 (Abce1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10214
Clone ID Related Accession (Same CDS sequence)	NM_015751.2
Accession Version	NM_015751.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family E member 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB651928.1, AK167370.1, CD564438.1 and AV213051.2. On Sep 8, 2006 this sequence version replaced NM_015751.1. ##Evidence-Data-START## Transcript exon combination :: AK049299.1, AK167130.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGACA AATTAACAAG AATTGCTATT GTCAACCACG ACAAATGCAA ACCTAAGAAA 
TGTCGACAGG AGTGCAAAAA GAGTTGCCCT GTGGTTCGGA TGGGAAAATT GTGCATAGAA 
GTTACACCCC AGAGCAAAAT AGCATGGATT TCTGAAACTC TCTGTATTGG TTGTGGTATT 
TGTATTAAGA AATGTCCCTT TGGCGCCTTA TCAATTGTCA ATTTGCCAAG CAACTTGGAA 
AAAGAAACAA CACATCGCTA CTGTGCCAAT GCCTTCAAGC TTCACAGGTT GCCTATCCCT 
CGTCCAGGTG AAGTTTTGGG ATTAGTTGGA ACTAATGGTA TTGGAAAGTC AACTGCACTA 
AAAATTTTAG CAGGAAAACA AAAGCCAAAC CTTGGAAAGT ATGATGATCC ACCTGATTGG 
CAAGAGATTT TGACTTATTT CCGTGGATCT GAATTACAAA ATTACTTTAC CAAGATTCTC 
GAAGATGACC TAAAAGCCAT TATCAAACCT CAATATGTAG ACCAAATTCC CAAGGCTGCA 
AAGGGGACAG TGGGCTCTAT TCTGGACCGA AAAGATGAAA CAAAGACACA GGCAATTGTA 
TGTCAGCAGC TTGATTTAAC TCACCTTAAA GAACGAAATG TCGAAGATCT TTCAGGAGGA 
GAGTTGCAGA GATTTGCTTG TGCTGTCGTT TGCATACAAA AGGCTGATAT TTTTATGTTT 
GATGAACCTT CTAGTTACCT CGATGTCAAG CAACGTTTAA AGGCTGCCAT TACGATTCGA 
TCTCTAATAA ATCCAGATAG ATATATCATT GTGGTGGAGC ATGATCTAAG TGTATTAGAC 
TATCTCTCTG ACTTCATCTG CTGTCTATAT GGGGTACCGA GTGCTTATGG TGTTGTCACG 
ATGCCTTTTA GTGTAAGAGA AGGCATAAAT ATATTTTTGG ATGGCTATGT TCCAACAGAG 
AACCTGAGGT TCAGGGATGC GTCGCTTGTT TTTAAGGTAG CTGAGACAGC AAATGAAGAA 
GAAGTTAAAA AGATGTGCAT GTATAAATAT CCCGGGATGA AGAAAAAGAT GGGAGAGTTC 
GAGCTAGCAA TTGTAGCTGG AGAGTTCACG GACTCTGAGA TCATGGTGAT GCTGGGGGAG 
AATGGTACAG GTAAAACTAC ATTTATCAGA ATGCTTGCTG GAAGGCTTAA ACCAGATGAA 
GGAGGAGAAG TGCCAGTTCT AAATGTCAGT TATAAGCCAC AGAAAATCAG TCCCAAATCA 
ACAGGAAGTG TTCGCCAGTT ACTGCATGAA AAGATCAGAG ATGCTTACAC GCATCCGCAG 
TTTGTGACTG ATGTAATGAA GCCCCTACAG ATTGAAAACA TCATTGACCA AGAGGTACAG 
ACATTGTCTG GTGGTGAACT TCAGCGAGTA GCTTTAGCTC TTTGTTTGGG CAAACCTGCT 
GACGTCTATT TGATTGATGA ACCTTCTGCA TATTTGGATT CTGAGCAAAG ATTAATGGCA 
GCTCGGGTCG TCAAACGTTT CATTCTCCAT GCAAAGAAGA CAGCTTTTGT TGTAGAACAT 
GACTTCATCA TGGCCACCTA TCTAGCAGAT CGCGTCATCG TTTTTGATGG TGTTCCATCA 
AAGAACACAG TTGCAAACAG TCCTCAGACT CTTTTGGCTG GCATGAACAA ATTTTTGTCT 
CAGCTCGAAA TTACATTCAG AAGAGACCCC AACAACTACA GGCCACGAAT AAATAAGCTC 
AATTCAATCA AGGATGTAGA ACAAAAGAAG AGTGGAAACT ACTTTTTCTT GGATGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056566.2
CDS	226..2025
Translation	MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD

Target ORF information:

RefSeq Version	NM_015751.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family E (OABP), member 1 (Abce1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015751.2

ORF Insert Sequence:

ATGGCAGACA AATTAACAAG AATTGCTATT GTCAACCACG ACAAATGCAA ACCTAAGAAA 
TGTCGACAGG AGTGCAAAAA GAGTTGCCCT GTGGTTCGGA TGGGAAAATT GTGCATAGAA 
GTTACACCCC AGAGCAAAAT AGCATGGATT TCTGAAACTC TCTGTATTGG TTGTGGTATT 
TGTATTAAGA AATGTCCCTT TGGCGCCTTA TCAATTGTCA ATTTGCCAAG CAACTTGGAA 
AAAGAAACAA CACATCGCTA CTGTGCCAAT GCCTTCAAGC TTCACAGGTT GCCTATCCCT 
CGTCCAGGTG AAGTTTTGGG ATTAGTTGGA ACTAATGGTA TTGGAAAGTC AACTGCACTA 
AAAATTTTAG CAGGAAAACA AAAGCCAAAC CTTGGAAAGT ATGATGATCC ACCTGATTGG 
CAAGAGATTT TGACTTATTT CCGTGGATCT GAATTACAAA ATTACTTTAC CAAGATTCTC 
GAAGATGACC TAAAAGCCAT TATCAAACCT CAATATGTAG ACCAAATTCC CAAGGCTGCA 
AAGGGGACAG TGGGCTCTAT TCTGGACCGA AAAGATGAAA CAAAGACACA GGCAATTGTA 
TGTCAGCAGC TTGATTTAAC TCACCTTAAA GAACGAAATG TCGAAGATCT TTCAGGAGGA 
GAGTTGCAGA GATTTGCTTG TGCTGTCGTT TGCATACAAA AGGCTGATAT TTTTATGTTT 
GATGAACCTT CTAGTTACCT CGATGTCAAG CAACGTTTAA AGGCTGCCAT TACGATTCGA 
TCTCTAATAA ATCCAGATAG ATATATCATT GTGGTGGAGC ATGATCTAAG TGTATTAGAC 
TATCTCTCTG ACTTCATCTG CTGTCTATAT GGGGTACCGA GTGCTTATGG TGTTGTCACG 
ATGCCTTTTA GTGTAAGAGA AGGCATAAAT ATATTTTTGG ATGGCTATGT TCCAACAGAG 
AACCTGAGGT TCAGGGATGC GTCGCTTGTT TTTAAGGTAG CTGAGACAGC AAATGAAGAA 
GAAGTTAAAA AGATGTGCAT GTATAAATAT CCCGGGATGA AGAAAAAGAT GGGAGAGTTC 
GAGCTAGCAA TTGTAGCTGG AGAGTTCACG GACTCTGAGA TCATGGTGAT GCTGGGGGAG 
AATGGTACAG GTAAAACTAC ATTTATCAGA ATGCTTGCTG GAAGGCTTAA ACCAGATGAA 
GGAGGAGAAG TGCCAGTTCT AAATGTCAGT TATAAGCCAC AGAAAATCAG TCCCAAATCA 
ACAGGAAGTG TTCGCCAGTT ACTGCATGAA AAGATCAGAG ATGCTTACAC GCATCCGCAG 
TTTGTGACTG ATGTAATGAA GCCCCTACAG ATTGAAAACA TCATTGACCA AGAGGTACAG 
ACATTGTCTG GTGGTGAACT TCAGCGAGTA GCTTTAGCTC TTTGTTTGGG CAAACCTGCT 
GACGTCTATT TGATTGATGA ACCTTCTGCA TATTTGGATT CTGAGCAAAG ATTAATGGCA 
GCTCGGGTCG TCAAACGTTT CATTCTCCAT GCAAAGAAGA CAGCTTTTGT TGTAGAACAT 
GACTTCATCA TGGCCACCTA TCTAGCAGAT CGCGTCATCG TTTTTGATGG TGTTCCATCA 
AAGAACACAG TTGCAAACAG TCCTCAGACT CTTTTGGCTG GCATGAACAA ATTTTTGTCT 
CAGCTCGAAA TTACATTCAG AAGAGACCCC AACAACTACA GGCCACGAAT AAATAAGCTC 
AATTCAATCA AGGATGTAGA ACAAAAGAAG AGTGGAAACT ACTTTTTCTT GGATGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte.
Oncotarget8(24)39012-39020(2017 Jun)
Jiao XF,Huang CJ,Wu D,Zhang JY,Long YT,Chen F,Li X,Huo LJ

Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons.
Neurochemistry international53(3-4)71-8(2008 Sep)
Sugiyama C,Kuramoto N,Nagashima R,Yoneyama M,Ogita K

Transcription profile during maternal to zygotic transition in the mouse embryo.
Reproduction, fertility, and development18(6)635-45(2006)
Li XY,Cui XS,Kim NH

Oligosyndactylism mice have an inversion of chromosome 8.
Genetics168(4)2099-112(2004 Dec)
Wise TL,Pravtcheva DD

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Abce1 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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