Gene Symbol | Sema3b |
Entrez Gene ID | 20347 |
Full Name | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
Synonyms | SemA,Semaa,sema5,semaV |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis. The encoded protein inhibits axonal extension. This protein is thought to be an osteoblast protein that regulates bone mass and affects skeletal homeostasis. A similar gene in humans functions as a tumor suppressor gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]. |