Msc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Msc
Entrez Gene ID	17681
Full Name	musculin
Synonyms	MyoR,bHLHa22
General protein information	Preferred Names musculin Names musculin myogenic repressor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 A3\|1 4.5 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001360810.1	NP_001347739.1	musculin isoform 2
XM_006495460.3	XP_006495523.1	musculin isoform X3
NM_010827.2	NP_034957.1	musculin isoform 1
XM_011238348.2	XP_011236650.1	musculin isoform X2
XM_006495458.3	XP_006495521.1	musculin isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MSC	XP_528162.3
Canis lupus familiaris (dog)	MSC	XP_544121.2
	MSC	XP_001082936.1
Mus musculus (house mouse)	Msc	NP_034957.1
Danio rerio (zebrafish)	LOC556396	XP_684279.3
Homo sapiens (human)	MSC	NP_005089.2
Xenopus tropicalis (tropical clawed frog)	msc	NP_001096235.1
Bos taurus (cattle)	MSC	NP_001179075.1
Rattus norvegicus (Norway rat)	Msc	NP_001178683.1
Gallus gallus (chicken)	MSC	XP_418293.4

Gene Ontology
Bibliography

Related articles in PubMed

The transcription factor musculin promotes the unidirectional development of peripheral T
Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, Han T, Oukka M, Kuchroo V
Nature immunology18(3)344-353(2017 Mar)

MyoR modulates cardiac conduction by repressing Gata4.
Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV
Molecular and cellular biology35(4)649-61(2015 Feb)

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.
Czajkowski MT, Rassek C, Lenhard DC, Br?hl D, Birchmeier C
Developmental biology395(2)307-16(2014 Nov)

Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation.
Chiu YK, Lin IY, Su ST, Wang KH, Yang SY, Tsai DY, Hsieh YT, Lin KI
Journal of immunology (Baltimore, Md. : 1950)193(5)2207-17(2014 Sep)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study shows that MSC-deficient TGFb-induced Treg cells are unable to suppress Th2 cell responses, and that MSC-deficient mice spontaneously develop gut and lung inflammation with age
Title: The transcription factor musculin promotes the unidirectional development of peripheral T

MyoR modulates cardiac conduction by repressing Gata4.
Title: MyoR modulates cardiac conduction by repressing Gata4.

results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation.
Title: Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation.

Basic helix-loop-helix transcriptional factor MyoR regulates BMP-7 in acute kidney injury.
Title: Basic helix-loop-helix transcriptional factor MyoR regulates BMP-7 in acute kidney injury.

MyoR is a transcription factor selectively up-regulated in CD4 T cells during Tfh cell differentiation
Title: Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo.

The following Msc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Msc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu27112	NM_001360810.1 Latest version!	Mus musculus musculin (Msc), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu27110	XM_006495458.3 Latest version!	Mus musculus musculin (Msc), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu27112	XM_006495460.3 Latest version!	Mus musculus musculin (Msc), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu68224	XM_011238348.2 Latest version!	Mus musculus musculin (Msc), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu06970	NM_010827.2 Latest version!	Mus musculus musculin (Msc), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Msc ( NM_001360810.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001347739.1 Mus musculus musculin (Msc), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu27112
Clone ID Related Accession (Same CDS sequence)	NM_001360810.1 , XM_006495460.3
Accession Version	NM_001360810.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	musculin isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115876.18. On Feb 14, 2018 this sequence version replaced XM_006495460.3. Transcript Variant: This variant (2) contains an alternate exon compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI078306.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA AAAATCATGT GGGCAACCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001347739.1
CDS	219..761
Translation	MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLKNHVGNP

Target ORF information:

RefSeq Version	NM_001360810.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus musculin (Msc), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001360810.1

ORF Insert Sequence:

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA AAAATCATGT GGGCAACCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msc ( XM_006495458.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495521.1 Mus musculus musculin (Msc), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27110
Clone ID Related Accession (Same CDS sequence)	XM_006495458.3
Accession Version	XM_006495458.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	musculin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495458.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGG TAGGGATGCT GCGCTCGAGG 
CCGGGGGACA GCAGCCCAGA GCGCTACCCG GGCCCAGGGC TGGCTCGGCC CCAGACGAAG 
AGCCAAGAGG GGAGGTTTCT GGAACCAGTG ACGTGGCCAT TCGTGGTCTC TGGACGCCCA 
GACTCTGACA GCAAAGACGT TTCTGCAGCC AACAGGCTTT GTGGAACTTC CGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495521.1
CDS	342..1058
Translation	MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLVGMLRSRPGDSSPERYPGPGLARPQTKSQEGRFLEPVTWPFVVSGRPDSDSKDVSAANRLCGTSA

Target ORF information:

RefSeq Version	XM_006495458.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus musculin (Msc), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495458.3

ORF Insert Sequence:

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGG TAGGGATGCT GCGCTCGAGG 
CCGGGGGACA GCAGCCCAGA GCGCTACCCG GGCCCAGGGC TGGCTCGGCC CCAGACGAAG 
AGCCAAGAGG GGAGGTTTCT GGAACCAGTG ACGTGGCCAT TCGTGGTCTC TGGACGCCCA 
GACTCTGACA GCAAAGACGT TTCTGCAGCC AACAGGCTTT GTGGAACTTC CGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msc ( XM_006495460.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006495523.1 Mus musculus musculin (Msc), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu27112
Clone ID Related Accession (Same CDS sequence)	NM_001360810.1 , XM_006495460.3
Accession Version	XM_006495460.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	musculin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495460.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA AAAATCATGT GGGCAACCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006495523.1
CDS	342..884
Translation	MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLKNHVGNP

Target ORF information:

RefSeq Version	XM_006495460.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus musculin (Msc), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006495460.3

ORF Insert Sequence:

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA AAAATCATGT GGGCAACCCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msc ( XM_011238348.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011236650.1 Mus musculus musculin (Msc), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu68224
Clone ID Related Accession (Same CDS sequence)	XM_011238348.2
Accession Version	XM_011238348.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	musculin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011238348.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGG TAGGGATGCT GCGCTCGAGG 
CCGGGGGACA GCAGCCCAGA GCGCTACCCG GGCCCAGGGC TGGCTCGGCC CCAGACGAAG 
AGCCAAGAGG GGAGGTTTCT GGAACCAGTG AAAAATCATG TGGGCAACCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011236650.1
CDS	342..995
Translation	MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLVGMLRSRPGDSSPERYPGPGLARPQTKSQEGRFLEPVKNHVGNP

Target ORF information:

RefSeq Version	XM_011238348.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus musculin (Msc), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011238348.2

ORF Insert Sequence:

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGG TAGGGATGCT GCGCTCGAGG 
CCGGGGGACA GCAGCCCAGA GCGCTACCCG GGCCCAGGGC TGGCTCGGCC CCAGACGAAG 
AGCCAAGAGG GGAGGTTTCT GGAACCAGTG AAAAATCATG TGGGCAACCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msc ( NM_010827.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034957.1 Mus musculus musculin (Msc), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu06970
Clone ID Related Accession (Same CDS sequence)	NM_010827.2
Accession Version	NM_010827.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	musculin isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115876.18. On Nov 17, 2006 this sequence version replaced NM_010827.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF087035.1, BC103592.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA CGTGGCCATT CGTGGTCTCT 
GGACGCCCAG ACTCTGACAG CAAAGACGTT TCTGCAGCCA ACAGGCTTTG TGGAACTTCC 
GCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034957.1
CDS	219..824
Translation	MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLTWPFVVSGRPDSDSKDVSAANRLCGTSA

Target ORF information:

RefSeq Version	NM_010827.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus musculin (Msc), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010827.2

ORF Insert Sequence:

ATGTCCACCG GCTCGGTGAG TGACCCCGAA GACTCGGAGA TGAGGGGGCT GCAGAGGGTC 
TACCCGGCCC CGGCCTCCAA GAGGCCGCCC CTGCTCCGCA TGGAGCGCGG TTACGGCTCG 
CCCAGCGACA TTTCTTCTGC GGAAGAGGAG GACGGTGAAG AGGAGCCCGG CTCCCTGGGA 
GCCGCGGGAG GATGCAAGAG GAAGCGGCTC CGTGGGGCTG ACGCTGGCGG CGCAGGTGGC 
CGCGCAGGCG GTGCGGGGAA GAAGCCGCTC CCGCCTAAGG GCTCGGCCGC AGAGTGCAAG 
CAGTCGCAGC GGAATGCGGC CAACGCCCGC GAACGCGCCC GGATGCGCGT GCTGAGCAAA 
GCCTTCTCCA GACTGAAGAC CAGCCTGCCC TGGGTGCCGC CCGACACCAA GCTTTCCAAA 
CTGGACACGC TGCGCCTGGC TTCCAGCTAC ATCGCGCACC TGCGCCAGCT GCTGCAGGAG 
GACCGCTACG AGGACAGCTA TGTGCACCCT GTGAACCTGA CGTGGCCATT CGTGGTCTCT 
GGACGCCCAG ACTCTGACAG CAAAGACGTT TCTGCAGCCA ACAGGCTTTG TGGAACTTCC 
GCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The transcription factor musculin promotes the unidirectional development of peripheral T
Nature immunology18(3)344-353(2017 Mar)
Wu C,Chen Z,Dardalhon V,Xiao S,Thalhamer T,Liao M,Madi A,Franca RF,Han T,Oukka M,Kuchroo V

MyoR modulates cardiac conduction by repressing Gata4.
Molecular and cellular biology35(4)649-61(2015 Feb)
Harris JP,Bhakta M,Bezprozvannaya S,Wang L,Lubczyk C,Olson EN,Munshi NV

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.
Developmental biology395(2)307-16(2014 Nov)
Czajkowski MT,Rassek C,Lenhard DC,Br?hl D,Birchmeier C

Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation.
Journal of immunology (Baltimore, Md. : 1950)193(5)2207-17(2014 Sep)
Chiu YK,Lin IY,Su ST,Wang KH,Yang SY,Tsai DY,Hsieh YT,Lin KI

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Msc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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