Kcnh1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnh1
Entrez Gene ID	16510
Full Name	potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms	EAG1,Kv10.1,M-eag
General protein information	Preferred Names potassium voltage-gated channel, subfamily H (eag-related), member 1 Names potassium voltage-gated channel subfamily H member 1 EAG channel 1 ether a go-go ether-a-go-go potassium channel 1 voltage-gated potassium channel subunit Kv10.1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 H6

mRNA and Protein(s)

mRNA	Protein	Name
XM_006497229.1	XP_006497292.1	potassium voltage-gated channel subfamily H member 1 isoform X1
NM_010600.3	NP_034730.1	potassium voltage-gated channel subfamily H member 1 isoform 1
NM_001038607.2	NP_001033696.1	potassium voltage-gated channel subfamily H member 1 isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Kcnh1	NP_113930.1
Xenopus tropicalis (tropical clawed frog)	kcnh1	XP_002934755.2
Canis lupus familiaris (dog)	LOC490277	XP_005623012.1
Mus musculus (house mouse)	Kcnh1	NP_001033696.1
Gallus gallus (chicken)	KCNH1	XP_419440.4
Homo sapiens (human)	KCNH1	NP_758872.1
Pan troglodytes (chimpanzee)	KCNH1	XP_001169423.2
	KCNH1	XP_001109251.1
Danio rerio (zebrafish)	kcnh1b	NP_001265743.1
Bos taurus (cattle)	KCNH1	NP_776797.1
Danio rerio (zebrafish)	kcnh1a	NP_001038396.1
Oryza sativa (rice)	Os01g0756700	NP_001044290.1

Gene Ontology
Bibliography

Related articles in PubMed

Screening for Non-Pore-Binding Modulators of EAG K+ Channels.
Fernandes AS, Morais-Cabral JH, Harley CA
Journal of biomolecular screening21(7)758-65(2016 Aug)

Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.
S?nchez A, Urrego D, Pardo LA
EMBO reports17(5)708-23(2016 05)

Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.
Urrego D, Movsisyan N, Ufartes R, Pardo LA
Cell cycle (Georgetown, Tex.)15(6)799-811(2016)

KV 10.1 opposes activity-dependent increase in Ca?? influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.
Mortensen LS, Schmidt H, Farsi Z, Barrantes-Freer A, Rubio ME, Ufartes R, Eilers J, Sakaba T, St?hmer W, Pardo LA
The Journal of physiology593(1)181-96(2015 01)

KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.
Jim?nez-Gardu?o AM, Mitkovski M, Alexopoulos IK, S?nchez A, St?hmer W, Pardo LA, Ortega A
Biochimica et biophysica acta1838(3)921-31(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

n this report, we present two independent screening campaigns in which we wanted to identify small molecules that bind to either the intracellular cytoplasmic amino terminal Per-Arnt-Sim (PAS) domain from the human EAG-related gene (ERG) channel or the amino or carboxy terminal globular domains from the mouse EAG1 channel, affecting their interaction.
Title: Screening for Non-Pore-Binding Modulators of EAG K+ Channels.

KV10.1 localizes to the centrosome and the primary cilium and promotes ciliary disassembly. Interference with KV10.1 ciliary localization abolishes not only the effects on ciliary disassembly, but also KV10.1-induced tumor progression in vivo Conversely.
Title: Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.

Expression of Kv10.1 driven by phosphorylated Rb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.
Title: Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

KV 10.1 opposes activity-dependent increase in calcium influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse
Title: KV 10.1 opposes activity-dependent increase in Ca?? influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.

2 A resolution crystal structure of the eag domain-CNBHD complex of the mouse EAG1 (also known as KCNH1) channel
Title: The structural mechanism of KCNH-channel regulation by the eag domain.

The following Kcnh1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnh1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu23734	NM_010600.3 Latest version!	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu23735	NM_001038607.2 Latest version!	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu29004	XM_006497229.1 Latest version!	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnh1 ( NM_010600.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034730.1 Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23734
Clone ID Related Accession (Same CDS sequence)	NM_010600.3
Accession Version	NM_010600.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2970bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily H member 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ104826.1, AK140193.1, AC109240.30, AK147461.1 and CJ256689.1. On Jun 26, 2014 this sequence version replaced NM_010600.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U04294.1, BC109013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCATGG CTGGCGGCCG GCGGGGACTA GTGGCCCCGC AGAACACGTT TCTGGAGAAC 
ATCGTGCGGC GGTCCAACGA CACTAATTTT GTGTTGGGGA ATGCCCAGAT AGTCGACTGG 
CCCATCGTGT ACAGCAATGA TGGATTCTGC AAGCTGTCTG GCTACCACCG GGCAGAAGTG 
ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TCCCACCACC ACTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGTTCTCTGA AAGTTGTGCG GCTGCTCCGT 
CTCGGGCGAG TGGCCCGCAA ACTGGATCAT TACATCGAGT ATGGAGCCGC GGTACTGGTC 
CTGTTGGTGT GCGTGTTTGG GCTTGCTGCC CACTGGATGG CCTGCATCTG GTACAGCATT 
GGGGACTATG AGATCTTTGA TGAAGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAACTGGCAT TGGACATCGG CACTCCATAC CAGTTTAATG GGTCTGGTTC AGGGAAGTGG 
GAAGGTGGGC CAAGCAAGAA CTCTGTCTAC ATCTCCTCGC TGTACTTCAC CATGACAAGT 
CTCACCAGTG TGGGCTTTGG TAACATTGCC CCATCCACAG ACATCGAGAA GATCTTCGCA 
GTGGCCATCA TGATGATTGG CTCTCTTCTG TATGCCACCA TCTTTGGGAA CGTGACAACC 
ATTTTCCAGC AGATGTACGC CAACACCAAC AGGTACCACG AGATGCTCAA CAGTGTCCGG 
GATTTCCTGA AGCTCTACCA GGTGCCCAAA GGGCTGAGTG AGCGGGTCAT GGACTACATT 
GTGTCCACCT GGTCCATGTC CCGAGGCATC GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGC GAGCCGACAT TTGCGTGCAC CTGAACCGCA AAGTGTTCAA AGAACACCCT 
GCCTTTCGAT TGGCCAGCGA TGGCTGCCTG CGGGCCTTGG CCATGGAGTT CCAGACAGTG 
CACTGTGCCC CAGGGGACCT CATCTATCAT GCTGGAGAGA GTGTGGACAG CCTCTGCTTC 
GTGGTCTCAG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT CCTAGGGAAA 
GGAGACGTGT TTGGGGATGT TTTCTGGAAG GAAGCTACCC TTGCACAGTC CTGTGCTAAT 
GTCCGGGCCT TGACCTACTG TGACCTGCAC GTGATCAAGA GGGACGCCCT TCAGAAAGTG 
CTAGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTGATTCT CACCTACAAC 
CTGAGGAAGA GGATTGTGTT CCGGAAGATC AGCGACGTGA AACGAGAAGA GGAGGAGAGG 
ATGAAACGGA AGAACGAGGC CCCCCTTATC CTGCCTCCTG ACCACCCCGT CAGAAGACTC 
TTCCAAAGGT TCCGCCAGCA GAAAGAAGCC AGGCTGGCAG CCGAGAGAGG GGGCCGGGAC 
CTGGATGACC TGGATGTAGA AAAGGGCAAT GCCCTCACGG ACCATACCTC AGCCAACCAC 
AGCCTGGTGA AGGCCAGTGT GGTCACGGTG CGTGAGAGCC CCGCCACGCC TGTGTCCTTC 
CAGGCGGCCA CCACCTCCAC CATGTCAGAC CACGCCAAGC TGCATGCCCC CGGATCTGAG 
TGCCTAGGTC CCAAGGCAGT CAGCTGTGAC CCTGCCAAGC GCAAAGGCTG GGCCCGTTTC 
AAAGATGCCT GTGGAAAGGG TGAGGATTGG AACAAGGTGT CCAAGGCAGA GTCCATGGAG 
ACGCTGCCCG AGAGGACAAA GGCACCGGGT GAGGCCACGC TGAAGAAGAC AGACTCCTGT 
GACAGCGGAA TCACCAAGAG CGACCTGCGC TTGGACAATG TGGGTGAGAC CAGGAGTCCT 
CAGGACCGGA GCCCCATCTT GGCTGAGGTC AAGCATTCTT TCTACCCCAT CCCTGAGCAG 
ACGCTGCAGG CCACAGTGCT GGAGGTGAAA TATGAGCTGA AGGAGGATAT CAAGGCCTTG 
AATGCCAAAA TGACCTCCAT TGAGAAGCAG CTGTCTGAGA TACTCAGGAT ACTAATGTCC 
AGAGGGTCCG CCCAATCTCC TCAGGAGACG GGTGAGATCT CCAGGCCCCA GTCCCCAGAG 
TCAGACAGAG ACATTTTTGG AGCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034730.1
CDS	232..3201
Translation	MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSANHSLVKASVVTVRESPATPVSFQAATTSTMSDHAKLHAPGSECLGPKAVSCDPAKRKGWARFKDACGKGEDWNKVSKAESMETLPERTKAPGEATLKKTDSCDSGITKSDLRLDNVGETRSPQDRSPILAEVKHSFYPIPEQTLQATVLEVKYELKEDIKALNAKMTSIEKQLSEILRILMSRGSAQSPQETGEISRPQSPESDRDIFGAS

Target ORF information:

RefSeq Version	NM_010600.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010600.3

ORF Insert Sequence:

ATGACCATGG CTGGCGGCCG GCGGGGACTA GTGGCCCCGC AGAACACGTT TCTGGAGAAC 
ATCGTGCGGC GGTCCAACGA CACTAATTTT GTGTTGGGGA ATGCCCAGAT AGTCGACTGG 
CCCATCGTGT ACAGCAATGA TGGATTCTGC AAGCTGTCTG GCTACCACCG GGCAGAAGTG 
ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TCCCACCACC ACTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGTTCTCTGA AAGTTGTGCG GCTGCTCCGT 
CTCGGGCGAG TGGCCCGCAA ACTGGATCAT TACATCGAGT ATGGAGCCGC GGTACTGGTC 
CTGTTGGTGT GCGTGTTTGG GCTTGCTGCC CACTGGATGG CCTGCATCTG GTACAGCATT 
GGGGACTATG AGATCTTTGA TGAAGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAACTGGCAT TGGACATCGG CACTCCATAC CAGTTTAATG GGTCTGGTTC AGGGAAGTGG 
GAAGGTGGGC CAAGCAAGAA CTCTGTCTAC ATCTCCTCGC TGTACTTCAC CATGACAAGT 
CTCACCAGTG TGGGCTTTGG TAACATTGCC CCATCCACAG ACATCGAGAA GATCTTCGCA 
GTGGCCATCA TGATGATTGG CTCTCTTCTG TATGCCACCA TCTTTGGGAA CGTGACAACC 
ATTTTCCAGC AGATGTACGC CAACACCAAC AGGTACCACG AGATGCTCAA CAGTGTCCGG 
GATTTCCTGA AGCTCTACCA GGTGCCCAAA GGGCTGAGTG AGCGGGTCAT GGACTACATT 
GTGTCCACCT GGTCCATGTC CCGAGGCATC GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGC GAGCCGACAT TTGCGTGCAC CTGAACCGCA AAGTGTTCAA AGAACACCCT 
GCCTTTCGAT TGGCCAGCGA TGGCTGCCTG CGGGCCTTGG CCATGGAGTT CCAGACAGTG 
CACTGTGCCC CAGGGGACCT CATCTATCAT GCTGGAGAGA GTGTGGACAG CCTCTGCTTC 
GTGGTCTCAG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT CCTAGGGAAA 
GGAGACGTGT TTGGGGATGT TTTCTGGAAG GAAGCTACCC TTGCACAGTC CTGTGCTAAT 
GTCCGGGCCT TGACCTACTG TGACCTGCAC GTGATCAAGA GGGACGCCCT TCAGAAAGTG 
CTAGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTGATTCT CACCTACAAC 
CTGAGGAAGA GGATTGTGTT CCGGAAGATC AGCGACGTGA AACGAGAAGA GGAGGAGAGG 
ATGAAACGGA AGAACGAGGC CCCCCTTATC CTGCCTCCTG ACCACCCCGT CAGAAGACTC 
TTCCAAAGGT TCCGCCAGCA GAAAGAAGCC AGGCTGGCAG CCGAGAGAGG GGGCCGGGAC 
CTGGATGACC TGGATGTAGA AAAGGGCAAT GCCCTCACGG ACCATACCTC AGCCAACCAC 
AGCCTGGTGA AGGCCAGTGT GGTCACGGTG CGTGAGAGCC CCGCCACGCC TGTGTCCTTC 
CAGGCGGCCA CCACCTCCAC CATGTCAGAC CACGCCAAGC TGCATGCCCC CGGATCTGAG 
TGCCTAGGTC CCAAGGCAGT CAGCTGTGAC CCTGCCAAGC GCAAAGGCTG GGCCCGTTTC 
AAAGATGCCT GTGGAAAGGG TGAGGATTGG AACAAGGTGT CCAAGGCAGA GTCCATGGAG 
ACGCTGCCCG AGAGGACAAA GGCACCGGGT GAGGCCACGC TGAAGAAGAC AGACTCCTGT 
GACAGCGGAA TCACCAAGAG CGACCTGCGC TTGGACAATG TGGGTGAGAC CAGGAGTCCT 
CAGGACCGGA GCCCCATCTT GGCTGAGGTC AAGCATTCTT TCTACCCCAT CCCTGAGCAG 
ACGCTGCAGG CCACAGTGCT GGAGGTGAAA TATGAGCTGA AGGAGGATAT CAAGGCCTTG 
AATGCCAAAA TGACCTCCAT TGAGAAGCAG CTGTCTGAGA TACTCAGGAT ACTAATGTCC 
AGAGGGTCCG CCCAATCTCC TCAGGAGACG GGTGAGATCT CCAGGCCCCA GTCCCCAGAG 
TCAGACAGAG ACATTTTTGG AGCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnh1 ( NM_001038607.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001033696.1 Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu23735
Clone ID Related Accession (Same CDS sequence)	NM_001038607.2
Accession Version	NM_001038607.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily H member 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ104826.1, AK147461.1 and CJ256689.1. On Jun 26, 2014 this sequence version replaced NM_001038607.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147461.1, SRR1660817.225108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCATGG CTGGCGGCCG GCGGGGACTA GTGGCCCCGC AGAACACGTT TCTGGAGAAC 
ATCGTGCGGC GGTCCAACGA CACTAATTTT GTGTTGGGGA ATGCCCAGAT AGTCGACTGG 
CCCATCGTGT ACAGCAATGA TGGATTCTGC AAGCTGTCTG GCTACCACCG GGCAGAAGTG 
ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGGCATCAGC 
AGCCTGTTCA GTTCTCTGAA AGTTGTGCGG CTGCTCCGTC TCGGGCGAGT GGCCCGCAAA 
CTGGATCATT ACATCGAGTA TGGAGCCGCG GTACTGGTCC TGTTGGTGTG CGTGTTTGGG 
CTTGCTGCCC ACTGGATGGC CTGCATCTGG TACAGCATTG GGGACTATGA GATCTTTGAT 
GAAGACACCA AGACCATCCG CAACAACAGC TGGCTCTACC AACTGGCATT GGACATCGGC 
ACTCCATACC AGTTTAATGG GTCTGGTTCA GGGAAGTGGG AAGGTGGGCC AAGCAAGAAC 
TCTGTCTACA TCTCCTCGCT GTACTTCACC ATGACAAGTC TCACCAGTGT GGGCTTTGGT 
AACATTGCCC CATCCACAGA CATCGAGAAG ATCTTCGCAG TGGCCATCAT GATGATTGGC 
TCTCTTCTGT ATGCCACCAT CTTTGGGAAC GTGACAACCA TTTTCCAGCA GATGTACGCC 
AACACCAACA GGTACCACGA GATGCTCAAC AGTGTCCGGG ATTTCCTGAA GCTCTACCAG 
GTGCCCAAAG GGCTGAGTGA GCGGGTCATG GACTACATTG TGTCCACCTG GTCCATGTCC 
CGAGGCATCG ACACAGAGAA GGTCCTGCAG ATCTGCCCCA AGGACATGCG AGCCGACATT 
TGCGTGCACC TGAACCGCAA AGTGTTCAAA GAACACCCTG CCTTTCGATT GGCCAGCGAT 
GGCTGCCTGC GGGCCTTGGC CATGGAGTTC CAGACAGTGC ACTGTGCCCC AGGGGACCTC 
ATCTATCATG CTGGAGAGAG TGTGGACAGC CTCTGCTTCG TGGTCTCAGG CTCCCTGGAG 
GTGATCCAGG ATGACGAGGT GGTGGCCATC CTAGGGAAAG GAGACGTGTT TGGGGATGTT 
TTCTGGAAGG AAGCTACCCT TGCACAGTCC TGTGCTAATG TCCGGGCCTT GACCTACTGT 
GACCTGCACG TGATCAAGAG GGACGCCCTT CAGAAAGTGC TAGAATTCTA CACAGCCTTC 
TCCCACTCCT TCTCCCGGAA CCTGATTCTC ACCTACAACC TGAGGAAGAG GATTGTGTTC 
CGGAAGATCA GCGACGTGAA ACGAGAAGAG GAGGAGAGGA TGAAACGGAA GAACGAGGCC 
CCCCTTATCC TGCCTCCTGA CCACCCCGTC AGAAGACTCT TCCAAAGGTT CCGCCAGCAG 
AAAGAAGCCA GGCTGGCAGC CGAGAGAGGG GGCCGGGACC TGGATGACCT GGATGTAGAA 
AAGGGCAATG CCCTCACGGA CCATACCTCA GCCAACCACA GCCTGGTGAA GGCCAGTGTG 
GTCACGGTGC GTGAGAGCCC CGCCACGCCT GTGTCCTTCC AGGCGGCCAC CACCTCCACC 
ATGTCAGACC ACGCCAAGCT GCATGCCCCC GGATCTGAGT GCCTAGGTCC CAAGGCAGTC 
AGCTGTGACC CTGCCAAGCG CAAAGGCTGG GCCCGTTTCA AAGATGCCTG TGGAAAGGGT 
GAGGATTGGA ACAAGGTGTC CAAGGCAGAG TCCATGGAGA CGCTGCCCGA GAGGACAAAG 
GCACCGGGTG AGGCCACGCT GAAGAAGACA GACTCCTGTG ACAGCGGAAT CACCAAGAGC 
GACCTGCGCT TGGACAATGT GGGTGAGACC AGGAGTCCTC AGGACCGGAG CCCCATCTTG 
GCTGAGGTCA AGCATTCTTT CTACCCCATC CCTGAGCAGA CGCTGCAGGC CACAGTGCTG 
GAGGTGAAAT ATGAGCTGAA GGAGGATATC AAGGCCTTGA ATGCCAAAAT GACCTCCATT 
GAGAAGCAGC TGTCTGAGAT ACTCAGGATA CTAATGTCCA GAGGGTCCGC CCAATCTCCT 
CAGGAGACGG GTGAGATCTC CAGGCCCCAG TCCCCAGAGT CAGACAGAGA CATTTTTGGA 
GCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033696.1
CDS	232..3120
Translation	MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSANHSLVKASVVTVRESPATPVSFQAATTSTMSDHAKLHAPGSECLGPKAVSCDPAKRKGWARFKDACGKGEDWNKVSKAESMETLPERTKAPGEATLKKTDSCDSGITKSDLRLDNVGETRSPQDRSPILAEVKHSFYPIPEQTLQATVLEVKYELKEDIKALNAKMTSIEKQLSEILRILMSRGSAQSPQETGEISRPQSPESDRDIFGAS

Target ORF information:

RefSeq Version	NM_001038607.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001038607.2

ORF Insert Sequence:

ATGACCATGG CTGGCGGCCG GCGGGGACTA GTGGCCCCGC AGAACACGTT TCTGGAGAAC 
ATCGTGCGGC GGTCCAACGA CACTAATTTT GTGTTGGGGA ATGCCCAGAT AGTCGACTGG 
CCCATCGTGT ACAGCAATGA TGGATTCTGC AAGCTGTCTG GCTACCACCG GGCAGAAGTG 
ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGGCATCAGC 
AGCCTGTTCA GTTCTCTGAA AGTTGTGCGG CTGCTCCGTC TCGGGCGAGT GGCCCGCAAA 
CTGGATCATT ACATCGAGTA TGGAGCCGCG GTACTGGTCC TGTTGGTGTG CGTGTTTGGG 
CTTGCTGCCC ACTGGATGGC CTGCATCTGG TACAGCATTG GGGACTATGA GATCTTTGAT 
GAAGACACCA AGACCATCCG CAACAACAGC TGGCTCTACC AACTGGCATT GGACATCGGC 
ACTCCATACC AGTTTAATGG GTCTGGTTCA GGGAAGTGGG AAGGTGGGCC AAGCAAGAAC 
TCTGTCTACA TCTCCTCGCT GTACTTCACC ATGACAAGTC TCACCAGTGT GGGCTTTGGT 
AACATTGCCC CATCCACAGA CATCGAGAAG ATCTTCGCAG TGGCCATCAT GATGATTGGC 
TCTCTTCTGT ATGCCACCAT CTTTGGGAAC GTGACAACCA TTTTCCAGCA GATGTACGCC 
AACACCAACA GGTACCACGA GATGCTCAAC AGTGTCCGGG ATTTCCTGAA GCTCTACCAG 
GTGCCCAAAG GGCTGAGTGA GCGGGTCATG GACTACATTG TGTCCACCTG GTCCATGTCC 
CGAGGCATCG ACACAGAGAA GGTCCTGCAG ATCTGCCCCA AGGACATGCG AGCCGACATT 
TGCGTGCACC TGAACCGCAA AGTGTTCAAA GAACACCCTG CCTTTCGATT GGCCAGCGAT 
GGCTGCCTGC GGGCCTTGGC CATGGAGTTC CAGACAGTGC ACTGTGCCCC AGGGGACCTC 
ATCTATCATG CTGGAGAGAG TGTGGACAGC CTCTGCTTCG TGGTCTCAGG CTCCCTGGAG 
GTGATCCAGG ATGACGAGGT GGTGGCCATC CTAGGGAAAG GAGACGTGTT TGGGGATGTT 
TTCTGGAAGG AAGCTACCCT TGCACAGTCC TGTGCTAATG TCCGGGCCTT GACCTACTGT 
GACCTGCACG TGATCAAGAG GGACGCCCTT CAGAAAGTGC TAGAATTCTA CACAGCCTTC 
TCCCACTCCT TCTCCCGGAA CCTGATTCTC ACCTACAACC TGAGGAAGAG GATTGTGTTC 
CGGAAGATCA GCGACGTGAA ACGAGAAGAG GAGGAGAGGA TGAAACGGAA GAACGAGGCC 
CCCCTTATCC TGCCTCCTGA CCACCCCGTC AGAAGACTCT TCCAAAGGTT CCGCCAGCAG 
AAAGAAGCCA GGCTGGCAGC CGAGAGAGGG GGCCGGGACC TGGATGACCT GGATGTAGAA 
AAGGGCAATG CCCTCACGGA CCATACCTCA GCCAACCACA GCCTGGTGAA GGCCAGTGTG 
GTCACGGTGC GTGAGAGCCC CGCCACGCCT GTGTCCTTCC AGGCGGCCAC CACCTCCACC 
ATGTCAGACC ACGCCAAGCT GCATGCCCCC GGATCTGAGT GCCTAGGTCC CAAGGCAGTC 
AGCTGTGACC CTGCCAAGCG CAAAGGCTGG GCCCGTTTCA AAGATGCCTG TGGAAAGGGT 
GAGGATTGGA ACAAGGTGTC CAAGGCAGAG TCCATGGAGA CGCTGCCCGA GAGGACAAAG 
GCACCGGGTG AGGCCACGCT GAAGAAGACA GACTCCTGTG ACAGCGGAAT CACCAAGAGC 
GACCTGCGCT TGGACAATGT GGGTGAGACC AGGAGTCCTC AGGACCGGAG CCCCATCTTG 
GCTGAGGTCA AGCATTCTTT CTACCCCATC CCTGAGCAGA CGCTGCAGGC CACAGTGCTG 
GAGGTGAAAT ATGAGCTGAA GGAGGATATC AAGGCCTTGA ATGCCAAAAT GACCTCCATT 
GAGAAGCAGC TGTCTGAGAT ACTCAGGATA CTAATGTCCA GAGGGTCCGC CCAATCTCCT 
CAGGAGACGG GTGAGATCTC CAGGCCCCAG TCCCCAGAGT CAGACAGAGA CATTTTTGGA 
GCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnh1 ( XM_006497229.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497292.1 Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant X2, mRNA.

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CloneID	OMu29004
Clone ID Related Accession (Same CDS sequence)	XM_006497229.1
Accession Version	XM_006497229.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2790bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily H member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TCCCACCACC ACTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGTTCTCTGA AAGTTGTGCG GCTGCTCCGT 
CTCGGGCGAG TGGCCCGCAA ACTGGATCAT TACATCGAGT ATGGAGCCGC GGTACTGGTC 
CTGTTGGTGT GCGTGTTTGG GCTTGCTGCC CACTGGATGG CCTGCATCTG GTACAGCATT 
GGGGACTATG AGATCTTTGA TGAAGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAACTGGCAT TGGACATCGG CACTCCATAC CAGTTTAATG GGTCTGGTTC AGGGAAGTGG 
GAAGGTGGGC CAAGCAAGAA CTCTGTCTAC ATCTCCTCGC TGTACTTCAC CATGACAAGT 
CTCACCAGTG TGGGCTTTGG TAACATTGCC CCATCCACAG ACATCGAGAA GATCTTCGCA 
GTGGCCATCA TGATGATTGG CTCTCTTCTG TATGCCACCA TCTTTGGGAA CGTGACAACC 
ATTTTCCAGC AGATGTACGC CAACACCAAC AGGTACCACG AGATGCTCAA CAGTGTCCGG 
GATTTCCTGA AGCTCTACCA GGTGCCCAAA GGGCTGAGTG AGCGGGTCAT GGACTACATT 
GTGTCCACCT GGTCCATGTC CCGAGGCATC GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGC GAGCCGACAT TTGCGTGCAC CTGAACCGCA AAGTGTTCAA AGAACACCCT 
GCCTTTCGAT TGGCCAGCGA TGGCTGCCTG CGGGCCTTGG CCATGGAGTT CCAGACAGTG 
CACTGTGCCC CAGGGGACCT CATCTATCAT GCTGGAGAGA GTGTGGACAG CCTCTGCTTC 
GTGGTCTCAG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT CCTAGGGAAA 
GGAGACGTGT TTGGGGATGT TTTCTGGAAG GAAGCTACCC TTGCACAGTC CTGTGCTAAT 
GTCCGGGCCT TGACCTACTG TGACCTGCAC GTGATCAAGA GGGACGCCCT TCAGAAAGTG 
CTAGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTGATTCT CACCTACAAC 
CTGAGGAAGA GGATTGTGTT CCGGAAGATC AGCGACGTGA AACGAGAAGA GGAGGAGAGG 
ATGAAACGGA AGAACGAGGC CCCCCTTATC CTGCCTCCTG ACCACCCCGT CAGAAGACTC 
TTCCAAAGGT TCCGCCAGCA GAAAGAAGCC AGGCTGGCAG CCGAGAGAGG GGGCCGGGAC 
CTGGATGACC TGGATGTAGA AAAGGGCAAT GCCCTCACGG ACCATACCTC AGCCAACCAC 
AGCCTGGTGA AGGCCAGTGT GGTCACGGTG CGTGAGAGCC CCGCCACGCC TGTGTCCTTC 
CAGGCGGCCA CCACCTCCAC CATGTCAGAC CACGCCAAGC TGCATGCCCC CGGATCTGAG 
TGCCTAGGTC CCAAGGCAGT CAGCTGTGAC CCTGCCAAGC GCAAAGGCTG GGCCCGTTTC 
AAAGATGCCT GTGGAAAGGG TGAGGATTGG AACAAGGTGT CCAAGGCAGA GTCCATGGAG 
ACGCTGCCCG AGAGGACAAA GGCACCGGGT GAGGCCACGC TGAAGAAGAC AGACTCCTGT 
GACAGCGGAA TCACCAAGAG CGACCTGCGC TTGGACAATG TGGGTGAGAC CAGGAGTCCT 
CAGGACCGGA GCCCCATCTT GGCTGAGGTC AAGCATTCTT TCTACCCCAT CCCTGAGCAG 
ACGCTGCAGG CCACAGTGCT GGAGGTGAAA TATGAGCTGA AGGAGGATAT CAAGGCCTTG 
AATGCCAAAA TGACCTCCAT TGAGAAGCAG CTGTCTGAGA TACTCAGGAT ACTAATGTCC 
AGAGGGTCCG CCCAATCTCC TCAGGAGACG GGTGAGATCT CCAGGCCCCA GTCCCCAGAG 
TCAGACAGAG ACATTTTTGG AGCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497292.1
CDS	183..2972
Translation	MQKSSACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSANHSLVKASVVTVRESPATPVSFQAATTSTMSDHAKLHAPGSECLGPKAVSCDPAKRKGWARFKDACGKGEDWNKVSKAESMETLPERTKAPGEATLKKTDSCDSGITKSDLRLDNVGETRSPQDRSPILAEVKHSFYPIPEQTLQATVLEVKYELKEDIKALNAKMTSIEKQLSEILRILMSRGSAQSPQETGEISRPQSPESDRDIFGAS

Target ORF information:

RefSeq Version	XM_006497229.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily H (eag-related), member 1 (Kcnh1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497229.1

ORF Insert Sequence:

ATGCAGAAAA GCAGCGCCTG CAGTTTTATG TATGGAGAGC TGACTGACAA GGACACAGTT 
GAAAAGGTTC GCCAGACCTT TGAGAACTAC GAGATGAATT CCTTCGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTTTTT GTGAAGATCG CTCCGATCAG GAACGAACAG 
GATAAAGTGG TCCTGTTCCT TTGCACTTTC AGCGACATAA CTGCATTCAA GCAGCCCATC 
GAGGACGACT CCTGCAAAGG TTGGGGGAAG TTTGCCCGAC TGACCAGAGC TCTGACAAGC 
AGCAGGGGAG TCCTGCAGCA GCTGGCCCCC AGTGTACAGA AGGGTGAGAA TGTTCACAAG 
CACTCGCGCC TGGCAGAGGT CCTGCAGCTG GGTTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCGCCAA AGACACCCCC TCACATCATC CTACACTACT GTGTCTTTAA GACCACGTGG 
GATTGGATCA TCTTGATCCT GACCTTCTAC ACAGCCATCT TGGTCCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAATAA TGTGGCCTGG CTGGTGGTGG ACAGCATCGT GGATGTCATC 
TTTTTGGTGG ACATTGTTTT GAATTTTCAC ACCACCTTTG TCGGGCCAGC GGGGGAAGTG 
ATATCTGACC CCAAACTTAT CCGCATGAAC TACCTGAAGA CGTGGTTTGT GATCGACCTT 
CTGTCCTGTT TGCCGTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TCCCACCACC ACTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGTTCTCTGA AAGTTGTGCG GCTGCTCCGT 
CTCGGGCGAG TGGCCCGCAA ACTGGATCAT TACATCGAGT ATGGAGCCGC GGTACTGGTC 
CTGTTGGTGT GCGTGTTTGG GCTTGCTGCC CACTGGATGG CCTGCATCTG GTACAGCATT 
GGGGACTATG AGATCTTTGA TGAAGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAACTGGCAT TGGACATCGG CACTCCATAC CAGTTTAATG GGTCTGGTTC AGGGAAGTGG 
GAAGGTGGGC CAAGCAAGAA CTCTGTCTAC ATCTCCTCGC TGTACTTCAC CATGACAAGT 
CTCACCAGTG TGGGCTTTGG TAACATTGCC CCATCCACAG ACATCGAGAA GATCTTCGCA 
GTGGCCATCA TGATGATTGG CTCTCTTCTG TATGCCACCA TCTTTGGGAA CGTGACAACC 
ATTTTCCAGC AGATGTACGC CAACACCAAC AGGTACCACG AGATGCTCAA CAGTGTCCGG 
GATTTCCTGA AGCTCTACCA GGTGCCCAAA GGGCTGAGTG AGCGGGTCAT GGACTACATT 
GTGTCCACCT GGTCCATGTC CCGAGGCATC GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGC GAGCCGACAT TTGCGTGCAC CTGAACCGCA AAGTGTTCAA AGAACACCCT 
GCCTTTCGAT TGGCCAGCGA TGGCTGCCTG CGGGCCTTGG CCATGGAGTT CCAGACAGTG 
CACTGTGCCC CAGGGGACCT CATCTATCAT GCTGGAGAGA GTGTGGACAG CCTCTGCTTC 
GTGGTCTCAG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT CCTAGGGAAA 
GGAGACGTGT TTGGGGATGT TTTCTGGAAG GAAGCTACCC TTGCACAGTC CTGTGCTAAT 
GTCCGGGCCT TGACCTACTG TGACCTGCAC GTGATCAAGA GGGACGCCCT TCAGAAAGTG 
CTAGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTGATTCT CACCTACAAC 
CTGAGGAAGA GGATTGTGTT CCGGAAGATC AGCGACGTGA AACGAGAAGA GGAGGAGAGG 
ATGAAACGGA AGAACGAGGC CCCCCTTATC CTGCCTCCTG ACCACCCCGT CAGAAGACTC 
TTCCAAAGGT TCCGCCAGCA GAAAGAAGCC AGGCTGGCAG CCGAGAGAGG GGGCCGGGAC 
CTGGATGACC TGGATGTAGA AAAGGGCAAT GCCCTCACGG ACCATACCTC AGCCAACCAC 
AGCCTGGTGA AGGCCAGTGT GGTCACGGTG CGTGAGAGCC CCGCCACGCC TGTGTCCTTC 
CAGGCGGCCA CCACCTCCAC CATGTCAGAC CACGCCAAGC TGCATGCCCC CGGATCTGAG 
TGCCTAGGTC CCAAGGCAGT CAGCTGTGAC CCTGCCAAGC GCAAAGGCTG GGCCCGTTTC 
AAAGATGCCT GTGGAAAGGG TGAGGATTGG AACAAGGTGT CCAAGGCAGA GTCCATGGAG 
ACGCTGCCCG AGAGGACAAA GGCACCGGGT GAGGCCACGC TGAAGAAGAC AGACTCCTGT 
GACAGCGGAA TCACCAAGAG CGACCTGCGC TTGGACAATG TGGGTGAGAC CAGGAGTCCT 
CAGGACCGGA GCCCCATCTT GGCTGAGGTC AAGCATTCTT TCTACCCCAT CCCTGAGCAG 
ACGCTGCAGG CCACAGTGCT GGAGGTGAAA TATGAGCTGA AGGAGGATAT CAAGGCCTTG 
AATGCCAAAA TGACCTCCAT TGAGAAGCAG CTGTCTGAGA TACTCAGGAT ACTAATGTCC 
AGAGGGTCCG CCCAATCTCC TCAGGAGACG GGTGAGATCT CCAGGCCCCA GTCCCCAGAG 
TCAGACAGAG ACATTTTTGG AGCAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Screening for Non-Pore-Binding Modulators of EAG K+ Channels.
Journal of biomolecular screening21(7)758-65(2016 Aug)
Fernandes AS,Morais-Cabral JH,Harley CA

Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.
EMBO reports17(5)708-23(2016 05)
S?nchez A,Urrego D,Pardo LA

Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.
Cell cycle (Georgetown, Tex.)15(6)799-811(2016)
Urrego D,Movsisyan N,Ufartes R,Pardo LA

KV 10.1 opposes activity-dependent increase in Ca?? influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.
The Journal of physiology593(1)181-96(2015 01)
Mortensen LS,Schmidt H,Farsi Z,Barrantes-Freer A,Rubio ME,Ufartes R,Eilers J,Sakaba T,St?hmer W,Pardo LA

KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.
Biochimica et biophysica acta1838(3)921-31(2014 Mar)
Jim?nez-Gardu?o AM,Mitkovski M,Alexopoulos IK,S?nchez A,St?hmer W,Pardo LA,Ortega A

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Kcnh1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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