Foxl1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Foxl1
Entrez Gene ID	14241
Full Name	forkhead box L1
Synonyms	FREAC7,Fkh6,fkh-6
General protein information	Preferred Names forkhead box L1 Names forkhead box protein L1 forkhead homolog 6 forkhead-related protein FKHL11 transcription factor FKH-6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 E1\|8 70.34 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008024.2	NP_032050.2	forkhead box protein L1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FOXL1	XP_005620647.1
Homo sapiens (human)	FOXL1	NP_005241.1
Pan troglodytes (chimpanzee)	FOXL1	XP_511154.2
Bos taurus (cattle)	FOXL1	XP_005218819.1
Mus musculus (house mouse)	Foxl1	NP_032050.2
Rattus norvegicus (Norway rat)	LOC687553	XP_006255788.1
Gallus gallus (chicken)	FOXL1	XP_001231599.2

Gene Ontology
Bibliography

Related articles in PubMed

Molecular architecture underlying fluid absorption by the developing inner ear.
Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ
eLife6(2017 Oct)

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of?Distinct Tumor Suppressor Genes.
Chan AL, La HM, Legrand JMD, M?kel? JA, Eichenlaub M, De Seram M, Ramialison M, Hobbs RM
Stem cell reports9(3)956-971(2017 Sep)

A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.
Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, L?dtke TH, Trowe MO, Kispert A
PLoS genetics13(8)e1006951(2017 Aug)

Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.
Mu?oz-Bravo JL, Flores-Mart?nez A, Herrero-Martin G, Puri S, Taketo MM, Rojas A, Hebrok M, Cano DA
PloS one11(10)e0164714(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Foxl1(+) hepatic progenitor cells and/or their descendants are required for the development of cholangiocytes and hepatocytes in liver injury models.
Title: Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury.

promotes liver repair after bile-duct-ligation-induced liver injury through activation of the canonical wnt/beta-catenin pathway
Title: Foxl1 promotes liver repair following cholestatic injury in mice.

Foxl1 is a bona fide marker of the facultative progenitor cell in the mouse liver.
Title: Foxl1 is a marker of bipotential hepatic progenitor cells in mice.

Mesenchymal Modifier of Min, plays a key role in gastrointestinal tumorigenesis.
Title: Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon.

link between a mesenchymal factor, Foxl1, and the regulation of a specific epithelial transport process in intestinal epithelium
Title: Foxl1 null mice have abnormal intestinal epithelia, postnatal growth retardation, and defective intestinal glucose uptake.

The following Foxl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58347	NM_008024.2 Latest version!	Mus musculus forkhead box L1 (Foxl1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Foxl1 ( NM_008024.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032050.2 Mus musculus forkhead box L1 (Foxl1), mRNA.

Price & Availability↑

CloneID	OMu58347
Clone ID Related Accession (Same CDS sequence)	NM_008024.2
Accession Version	NM_008024.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	forkhead box protein L1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC127554.4. On Jan 5, 2007 this sequence version replaced NM_008024.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGAGCCACC TCTTCAGTCC CCCGCTGGCC GCTCTGGCAG CCTCGCCGCT GTTGTACGTG 
TACAGCCCCG AGAGGCCTGG GCTGCCCCTG GCCTTCGCCC CTGCGGCTGC ACTGGCCGGC 
CCGGGCCGCG TCGAGCCCCC GCAGAAGCCG CCCTACAGCT ACATCGCTCT TATAGCCATG 
GCGATCCAGG ATGCTCCCGA GCAGAGGGTC ACACTGAACG GCATCTACCA GTTCATCATG 
GATCGCTTCC CGTTCTACCA CGACAACCGC CAAGGCTGGC AGAACAGCAT CCGCCACAAC 
CTGTCGCTCA ACGAGTGCTT CGTGAAGGTG CCACGTGAGA AGGGGCGGCC GGGCAAGGGC 
AGCTACTGGA CCCTGGACCC CCGCTGCTTG GACATGTTTG AGAACGGCAA TTATCGGCGC 
AGGAAGAGGA AGCCCAAGCC CGCCGCGGGT TCCCCGGAGG CCAAGCGCAC CCGGGTCGAG 
CCGCCGGAGT CCGAGGTGGG CTGCGATGTA GGGTCCCCGG ACCTGGCCAC TGCACTCCCG 
ACGCGCGCGC CGGATCGCTC CCAATCCCCG GCAGTAGGCA CCGCGCGGCC CGCGCTCCTT 
CCCTGGCCCG GCCCTGAGCC CCGGGACCCC GACGCGGACC TCACAGTCCA GGGCGCAGGG 
GCAGTGGCAA GCGGCCAGCT CCAGCGTCCG GCACACCACC TGGGGTCCCC TCTGTGCCCC 
GCCCCCAGCG GCTCCCCAAA AGGTTCCAAG TCAAAGAGTT TCAGCATCGA CAGCATCTTG 
GCCGTGAGAC CGACGCCAGC CTCAGGGGCC GAAGCACCGG GGATCCCTAA GCCCGTGCCT 
GGCGCGCTGG GCTCCTCTCT GCTGGCTGCC TCCTCCGGCC TAGCGCCTCC CTTCAACGCT 
TCGCTGGTCT TCGACGCGCA CGTCCAGGGC GGCTTTTCCC AGCTGGGGAT TCCCTTCCTT 
TCTTATTTTC CTCTGCAGGT TCCCGAGGCC ACAGTGCTTC GTTTCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032050.2
CDS	278..1288
Translation	MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGRVEPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRTRVEPPESEVGCDVGSPDLATALPTRAPDRSQSPAVGTARPALLPWPGPEPRDPDADLTVQGAGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEAPGIPKPVPGALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFLSYFPLQVPEATVLRFH

Target ORF information:

RefSeq Version	NM_008024.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus forkhead box L1 (Foxl1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008024.2

ORF Insert Sequence:

ATGAGCCACC TCTTCAGTCC CCCGCTGGCC GCTCTGGCAG CCTCGCCGCT GTTGTACGTG 
TACAGCCCCG AGAGGCCTGG GCTGCCCCTG GCCTTCGCCC CTGCGGCTGC ACTGGCCGGC 
CCGGGCCGCG TCGAGCCCCC GCAGAAGCCG CCCTACAGCT ACATCGCTCT TATAGCCATG 
GCGATCCAGG ATGCTCCCGA GCAGAGGGTC ACACTGAACG GCATCTACCA GTTCATCATG 
GATCGCTTCC CGTTCTACCA CGACAACCGC CAAGGCTGGC AGAACAGCAT CCGCCACAAC 
CTGTCGCTCA ACGAGTGCTT CGTGAAGGTG CCACGTGAGA AGGGGCGGCC GGGCAAGGGC 
AGCTACTGGA CCCTGGACCC CCGCTGCTTG GACATGTTTG AGAACGGCAA TTATCGGCGC 
AGGAAGAGGA AGCCCAAGCC CGCCGCGGGT TCCCCGGAGG CCAAGCGCAC CCGGGTCGAG 
CCGCCGGAGT CCGAGGTGGG CTGCGATGTA GGGTCCCCGG ACCTGGCCAC TGCACTCCCG 
ACGCGCGCGC CGGATCGCTC CCAATCCCCG GCAGTAGGCA CCGCGCGGCC CGCGCTCCTT 
CCCTGGCCCG GCCCTGAGCC CCGGGACCCC GACGCGGACC TCACAGTCCA GGGCGCAGGG 
GCAGTGGCAA GCGGCCAGCT CCAGCGTCCG GCACACCACC TGGGGTCCCC TCTGTGCCCC 
GCCCCCAGCG GCTCCCCAAA AGGTTCCAAG TCAAAGAGTT TCAGCATCGA CAGCATCTTG 
GCCGTGAGAC CGACGCCAGC CTCAGGGGCC GAAGCACCGG GGATCCCTAA GCCCGTGCCT 
GGCGCGCTGG GCTCCTCTCT GCTGGCTGCC TCCTCCGGCC TAGCGCCTCC CTTCAACGCT 
TCGCTGGTCT TCGACGCGCA CGTCCAGGGC GGCTTTTCCC AGCTGGGGAT TCCCTTCCTT 
TCTTATTTTC CTCTGCAGGT TCCCGAGGCC ACAGTGCTTC GTTTCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular architecture underlying fluid absorption by the developing inner ear.
eLife6(2017 Oct)
Honda K,Kim SH,Kelly MC,Burns JC,Constance L,Li X,Zhou F,Hoa M,Kelley MW,Wangemann P,Morell RJ,Griffith AJ

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of?Distinct Tumor Suppressor Genes.
Stem cell reports9(3)956-971(2017 Sep)
Chan AL,La HM,Legrand JMD,M?kel? JA,Eichenlaub M,De Seram M,Ramialison M,Hobbs RM

A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.
PLoS genetics13(8)e1006951(2017 Aug)
Bohnenpoll T,Wittern AB,Mamo TM,Weiss AC,Rudat C,Kleppa MJ,Schuster-Gossler K,Wojahn I,L?dtke TH,Trowe MO,Kispert A

Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.
PloS one11(10)e0164714(2016)
Mu?oz-Bravo JL,Flores-Mart?nez A,Herrero-Martin G,Puri S,Taketo MM,Rojas A,Hebrok M,Cano DA

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Foxl1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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