The following Capn3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Capn3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu20313 | |
| Clone ID Related Accession (Same CDS sequence) | NM_007601.3 | |
| Accession Version | NM_007601.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2466bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | calpain-3 isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY142198.1, CN664345.1, BC139790.1, AL935121.9, BC090661.1 and BB202194.1. On Apr 28, 2010 this sequence version replaced NM_007601.2. Transcript Variant: This variant (a) is the longest transcript and it encodes the longest protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC139790.1, X92523.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCAACTG TTATTAGTCC AACTGTGGCC CCAAGGACGG GGGCTGAGCC CAGGTCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_031627.2 |
| CDS | 281..2746 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_007601.3 |
1 | ATGCCAACTG TTATTAGTCC AACTGTGGCC CCAAGGACGG GGGCTGAGCC CAGGTCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu20322 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001109761.2 | |
| Accession Version | NM_001109761.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | calpain-3 isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090661.1 and BB202194.1. On Apr 28, 2010 this sequence version replaced NM_001109761.1. Transcript Variant: This variant (b) has multiple differences, compared to variant a. The resulting protein (isoform b) is shorter and has a distinct N-terminus when it is compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090661.1, AF091998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCCCTACC TGCTGCCGGG ATTCTTCTGT GACAGGGTGA TCCGAGAAAG GGACAGGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001103231.1 |
| CDS | 74..2203 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001109761.2 |
1 | ATGCCCTACC TGCTGCCGGG ATTCTTCTGT GACAGGGTGA TCCGAGAAAG GGACAGGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu20505 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001177799.1 | |
| Accession Version | NM_001177799.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | calpain-3 isoform c | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY142198.1, CN664345.1, AF127766.2, BC139790.1, BC090661.1 and BB202194.1. Transcript Variant: This variant (c) lacks several alternate, in-frame coding exons, compared to variant a. The resulting protein (isoform c) is shorter when it is compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF127766.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCAACTG TTATTAGTCC AACTGTGGCC CCAAGGACGG GGGCTGAGCC CAGGTCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001171270.1 |
| CDS | 281..2470 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001177799.1 |
1 | ATGCCAACTG TTATTAGTCC AACTGTGGCC CCAAGGACGG GGGCTGAGCC CAGGTCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis. |
Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy). |
Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. |
