Irak2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Irak2
Entrez Gene ID	108960
Full Name	interleukin-1 receptor-associated kinase 2
Synonyms	6330415L08Rik,AI649099,IRAK-2
General protein information	Preferred Names interleukin-1 receptor-associated kinase 2 Names interleukin-1 receptor-associated kinase-like 2 interleukin-1 receptor-associated kinase 2c mu-IRAK-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 E3\|6 52.82 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006505325.3	XP_006505388.1	interleukin-1 receptor-associated kinase-like 2 isoform X1
XM_006505325.4	XP_006505388.1	interleukin-1 receptor-associated kinase-like 2 isoform X1
NM_001113553.1	NP_001107025.1	interleukin-1 receptor-associated kinase-like 2 isoform b
NM_172161.4	NP_751893.3	interleukin-1 receptor-associated kinase-like 2 isoform a

Pathways from BioSystems

Homologies

Bos taurus (cattle)	IRAK2	NP_001069164.1
Mus musculus (house mouse)	Irak2	NP_751893.3
Rattus norvegicus (Norway rat)	Irak2	NP_001020593.1
Xenopus tropicalis (tropical clawed frog)	irak2	NP_001007501.1
Canis lupus familiaris (dog)	IRAK2	XP_005632225.1
	IRAK2	XP_001090790.1
Gallus gallus (chicken)	IRAK2	NP_001025776.1
Homo sapiens (human)	IRAK2	NP_001561.3
Pan troglodytes (chimpanzee)	IRAK2	XP_516275.4

Gene Ontology
Bibliography

Related articles in PubMed

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.
Zhou H, Bulek K, Li X, Herjan T, Yu M, Qian W, Wang H, Zhou G, Chen X, Yang H, Hong L, Zhao J, Qin L, Fukuda K, Flotho A, Gao J, Dongre A, Carman JA, Kang Z, Su B, Kern TS, Smith JD, Hamilton TA, Melchior F, Fox PL, Li X
eLife6(2017 Oct)

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling.
Mertins P, Przybylski D, Yosef N, Qiao J, Clauser K, Raychowdhury R, Eisenhaure TM, Maritzen T, Haucke V, Satoh T, Akira S, Carr SA, Regev A, Hacohen N, Chevrier N
Cell reports19(13)2853-2866(2017 Jun)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Sun J, Li N, Oh KS, Dutta B, Vayttaden SJ, Lin B, Ebert TS, De Nardo D, Davis J, Bagirzadeh R, Lounsbury NW, Pasare C, Latz E, Hornung V, Fraser ID
Science signaling9(409)ra3(2016 Jan)

The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.
Ma J, Bang BR, Lu J, Eun SY, Otsuka M, Croft M, Tobias P, Han J, Takeuchi O, Akira S, Karin M, Yagita H, Kang YJ
Science signaling6(295)ra87(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results establish that the IRAK2-TRAF6 interaction is rate limiting for the late, but not the early phase of cytokine production in bone marrow-derived macrophages and plasmacytoid dendritic cells
Title: Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.

These findings demonstrate an unexpected linkage of the innate immunity machinery to unfolded protein response signaling, revealing IRAK2 as a novel amplifier of the IRE1 pathway.
Title: Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling.

IRAK2 plays a key role in the TLR9-mediated transcriptional regulation of Irak-m expression by sustaining activation of PKD1 and NF-kappaB
Title: Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA.

IRAK-2 mediates pathology in a CD4 T cell specific manner by promoting Th17 cell development through enhancement of IL-1beta-induced activation of transcription factors RORgammat and BATF.
Title: IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.

the kinase activity of IRAK2 is required for the optimal activation of mitogen-activated protein kinase signaling, which regulates cytokine and chemokine production at posttranscriptional levels.
Title: The kinase activity of interleukin-1 receptor-associated kinase 2 is essential for lipopolysaccharide-mediated cytokine and chemokine mRNA stability and translation.

The following Irak2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irak2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15272	NM_172161.4 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	Quote Price
OMu15458	NM_001113553.1 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	Quote Price
OMu36744	XM_006505325.4 Latest version!	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	Quote Price
View Old Accession Versions >>
OMu36744	XM_006505325.3	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	Quote Price
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Irak2 ( NM_172161.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_751893.3 Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15272
Clone ID Related Accession (Same CDS sequence)	NM_172161.4
Accession Version	NM_172161.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase-like 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY110939.1, AY162378.1, AK078062.1 and CJ212338.1. On Jan 17, 2008 this sequence version replaced NM_172161.3. Transcript Variant: This variant (1) represents the longer transcript and enodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148248.1, AK150056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTGCT ACATCTACCA GCTGCCGTCC TGGGTGCTGG ACGACCTGTG CCGCAATATC 
GACACGCTCA GTGAGTGGGA CTGGATGCAG TTCGCTTCCT ACGTGATCAC AGACCTGACA 
CAGCTGAGGA AGATCAAGTC CATGGAGAGG GTCCAGGGGG TGAGCATCAC CCGGGAGCTA 
CTGTGGTGGT GGTCCATGCG GCAGGCCACG GTCCAGCAGC TGGTGGACCT CCTGTGTCAC 
CTGGAACTCT ACCGAGCTGC CCAGATTGTC TTGAGCTGGA AGCCGGTTCC TGAGAGCACA 
TCTCCCCTCC CAGCCTTCCC AGAGGCTGTG AAGCCAGGGG CTGTGGCTAC TTCTAGAAGA 
AACCTCAAGG ATGAACAGGA GAAAGTCCGG CCTGTGAAGC CACGTTCCCT TCTAGACACA 
GGGCCCATCA TGGCTGGGGC CCAGCGGCAG CGTCCGTGCG AGATGGATGC CCCTTGTTCC 
CTGAAAACTG ATGCACCCGA CTCTCCCCAG TCTAAGTATT GCAGTACTTC CACATCTGCC 
CCCAAGCAAG AAAGGCTTTT GGGTTTGCCC GGAGACAGGC TTTTCTGGAG TGAAGCAGAT 
GTCGTCCAAG CAACTGAGGA CTTTGACCAA AGCCACCGAA TCAGCGAGGG CACCTTTGCC 
GATATCTACC AGGGTCAAAG GAACGGTGTG GCCTTCGCCT TCAAGAAGCT CAGGGAGGTG 
GCCGGCTCCA GTCCAGGGTC CATGGACAGA TTCCTACAGG CAGAGATGCA GCTCTGCCTC 
AGATGCTGCC ACGCGAACGT CCTACCTCTG CTGGGTTTCT GCACTGGAAG ACAGTTCCAC 
AGCCTCATCT ACCCCTACAT GGCAAATGGC TCTCTGCACG ACAGACTCTG GGCTCAGGGC 
AACTCAGACA TGCTGCCCTG GCCACAGCGG GCCAGCATCT GCTCAGGGCT GCTTCTAGCC 
GTGGAGCACC TGCATAGCCT GGACATCATC CACAGCAATG TTAAGAGTGC CAACGTCTTG 
CTGGACCAGC ATCTTAACCC CAAGCTGGCT CATCCTGTGG CTCACCCTCA TCCCGACAAT 
AAAAAGACCA AATATACCGT CATGAGGACT CACCTGTTCC AGGCCTCAGC TGCATATCTG 
CCGGAACACT TCATCAGAGT GGGGCAGCTG ACCAAGCAGG TGGACATCTT CAGCTGTGGA 
ATTGTATTGG CCGAGGTCCT TACCGGCATC CCTGCGATGG ACAAGGACCG CAGTCCAGTT 
TACCTGAAGG ATTTGCTTCT CAGTGAGATT CCCAACAGTA CTTCTTCAGT CTGCTCCAGG 
AAGACCAGCA TGGGGAAGGC AGTGGTGAAA GAGATCTGCC AGAGACATGT GGAGAAGAGG 
GCAGGGCTGC TGCCTGAGGC CTGTGAGGAA GCCTGGGCCA CCGCTGTGAG TGTCTGCCTG 
CGGAGGCGCA ATGCCAGCGT GGAGGAGGCA CGAGTCTCCC TGGCCGGGGT GGAGGAGCAA 
CTCCGAGGGC AGCTGTCCCT TCCCTGGAGC AGGGTTTCTG AGGCCACAGG CTCATCTTCC 
AATACCCCGG AGGAAACAGA TGACGTTGAC AATTCCAGCC TCAGCGTCCC TTCTTTGGTT 
ATGATGGCAT CGTGCCCAGG GGCTGCCTCC TCTCCACTCT TCACGGGACA TGGAGCAGCA 
CAGCCATCCA CCAGTGGGAG ACAGGAGGCT GACTCCTCGT CAGAGGCTTG CACAGGCCCA 
CAGACACCCC AGAACGCTAC AGAGACTTCA TGGAAAATTG AGATCAATGA AGCCAAAAGG 
AGACTGATGG AGAACATCGT ACTCTACAAA GAAGAGAGAC TGGACAGCAG CGAGCTCTTT 
GGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_751893.3
CDS	82..1950
Translation	MACYIYQLPSWVLDDLCRNIDTLSEWDWMQFASYVITDLTQLRKIKSMERVQGVSITRELLWWWSMRQATVQQLVDLLCHLELYRAAQIVLSWKPVPESTSPLPAFPEAVKPGAVATSRRNLKDEQEKVRPVKPRSLLDTGPIMAGAQRQRPCEMDAPCSLKTDAPDSPQSKYCSTSTSAPKQERLLGLPGDRLFWSEADVVQATEDFDQSHRISEGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFHSLIYPYMANGSLHDRLWAQGNSDMLPWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCSRKTSMGKAVVKEICQRHVEKRAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPEETDDVDNSSLSVPSLVMMASCPGAASSPLFTGHGAAQPSTSGRQEADSSSEACTGPQTPQNATETSWKIEINEAKRRLMENIVLYKEERLDSSELFGP

Target ORF information:

RefSeq Version	NM_172161.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172161.4

ORF Insert Sequence:

ATGGCTTGCT ACATCTACCA GCTGCCGTCC TGGGTGCTGG ACGACCTGTG CCGCAATATC 
GACACGCTCA GTGAGTGGGA CTGGATGCAG TTCGCTTCCT ACGTGATCAC AGACCTGACA 
CAGCTGAGGA AGATCAAGTC CATGGAGAGG GTCCAGGGGG TGAGCATCAC CCGGGAGCTA 
CTGTGGTGGT GGTCCATGCG GCAGGCCACG GTCCAGCAGC TGGTGGACCT CCTGTGTCAC 
CTGGAACTCT ACCGAGCTGC CCAGATTGTC TTGAGCTGGA AGCCGGTTCC TGAGAGCACA 
TCTCCCCTCC CAGCCTTCCC AGAGGCTGTG AAGCCAGGGG CTGTGGCTAC TTCTAGAAGA 
AACCTCAAGG ATGAACAGGA GAAAGTCCGG CCTGTGAAGC CACGTTCCCT TCTAGACACA 
GGGCCCATCA TGGCTGGGGC CCAGCGGCAG CGTCCGTGCG AGATGGATGC CCCTTGTTCC 
CTGAAAACTG ATGCACCCGA CTCTCCCCAG TCTAAGTATT GCAGTACTTC CACATCTGCC 
CCCAAGCAAG AAAGGCTTTT GGGTTTGCCC GGAGACAGGC TTTTCTGGAG TGAAGCAGAT 
GTCGTCCAAG CAACTGAGGA CTTTGACCAA AGCCACCGAA TCAGCGAGGG CACCTTTGCC 
GATATCTACC AGGGTCAAAG GAACGGTGTG GCCTTCGCCT TCAAGAAGCT CAGGGAGGTG 
GCCGGCTCCA GTCCAGGGTC CATGGACAGA TTCCTACAGG CAGAGATGCA GCTCTGCCTC 
AGATGCTGCC ACGCGAACGT CCTACCTCTG CTGGGTTTCT GCACTGGAAG ACAGTTCCAC 
AGCCTCATCT ACCCCTACAT GGCAAATGGC TCTCTGCACG ACAGACTCTG GGCTCAGGGC 
AACTCAGACA TGCTGCCCTG GCCACAGCGG GCCAGCATCT GCTCAGGGCT GCTTCTAGCC 
GTGGAGCACC TGCATAGCCT GGACATCATC CACAGCAATG TTAAGAGTGC CAACGTCTTG 
CTGGACCAGC ATCTTAACCC CAAGCTGGCT CATCCTGTGG CTCACCCTCA TCCCGACAAT 
AAAAAGACCA AATATACCGT CATGAGGACT CACCTGTTCC AGGCCTCAGC TGCATATCTG 
CCGGAACACT TCATCAGAGT GGGGCAGCTG ACCAAGCAGG TGGACATCTT CAGCTGTGGA 
ATTGTATTGG CCGAGGTCCT TACCGGCATC CCTGCGATGG ACAAGGACCG CAGTCCAGTT 
TACCTGAAGG ATTTGCTTCT CAGTGAGATT CCCAACAGTA CTTCTTCAGT CTGCTCCAGG 
AAGACCAGCA TGGGGAAGGC AGTGGTGAAA GAGATCTGCC AGAGACATGT GGAGAAGAGG 
GCAGGGCTGC TGCCTGAGGC CTGTGAGGAA GCCTGGGCCA CCGCTGTGAG TGTCTGCCTG 
CGGAGGCGCA ATGCCAGCGT GGAGGAGGCA CGAGTCTCCC TGGCCGGGGT GGAGGAGCAA 
CTCCGAGGGC AGCTGTCCCT TCCCTGGAGC AGGGTTTCTG AGGCCACAGG CTCATCTTCC 
AATACCCCGG AGGAAACAGA TGACGTTGAC AATTCCAGCC TCAGCGTCCC TTCTTTGGTT 
ATGATGGCAT CGTGCCCAGG GGCTGCCTCC TCTCCACTCT TCACGGGACA TGGAGCAGCA 
CAGCCATCCA CCAGTGGGAG ACAGGAGGCT GACTCCTCGT CAGAGGCTTG CACAGGCCCA 
CAGACACCCC AGAACGCTAC AGAGACTTCA TGGAAAATTG AGATCAATGA AGCCAAAAGG 
AGACTGATGG AGAACATCGT ACTCTACAAA GAAGAGAGAC TGGACAGCAG CGAGCTCTTT 
GGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak2 ( NM_001113553.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001107025.1 Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15458
Clone ID Related Accession (Same CDS sequence)	NM_001113553.1
Accession Version	NM_001113553.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase-like 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY110939.1, AY162379.1, AK078062.1 and CJ212338.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is smaller compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK078062.1, AK151428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTGCT ACATCTACCA GCTGCCGTCC TGGGTGCTGG ACGACCTGTG CCGCAATATC 
GACACGCTCA GTGAGTGGGA CTGGATGCAG TTCGCTTCCT ACGTGATCAC AGACCTGACA 
CAGCTGAGGA AGATCAAGTC CATGGAGAGG GTCCAGGGGG TGAGCATCAC CCGGGAGCTA 
CTGTGGTGGT GGTCCATGCG GCAGGCCACG GTCCAGCAGC TGGTGGACCT CCTGTGTCAC 
CTGGAACTCT ACCGAGCTGC CCAGATTGTC TTGAGCTGGC CCATCATGGC TGGGGCCCAG 
CGGCAGCGTC CGTGCGAGAT GGATGCCCCT TGTTCCCTGA AAACTGATGC ACCCGACTCT 
CCCCAGTCTA AGTATTGCAG TACTTCCACA TCTGCCCCCA AGCAAGAAAG GCTTTTGGGT 
TTGCCCGGAG ACAGGCTTTT CTGGAGTGAA GCAGATGTCG TCCAAGCAAC TGAGGACTTT 
GACCAAAGCC ACCGAATCAG CGAGGGCACC TTTGCCGATA TCTACCAGGG TCAAAGGAAC 
GGTGTGGCCT TCGCCTTCAA GAAGCTCAGG GAGGTGGCCG GCTCCAGTCC AGGGTCCATG 
GACAGATTCC TACAGGCAGA GATGCAGCTC TGCCTCAGAT GCTGCCACGC GAACGTCCTA 
CCTCTGCTGG GTTTCTGCAC TGGAAGACAG TTCCACAGCC TCATCTACCC CTACATGGCA 
AATGGCTCTC TGCACGACAG ACTCTGGGCT CAGGGCAACT CAGACATGCT GCCCTGGCCA 
CAGCGGGCCA GCATCTGCTC AGGGCTGCTT CTAGCCGTGG AGCACCTGCA TAGCCTGGAC 
ATCATCCACA GCAATGTTAA GAGTGCCAAC GTCTTGCTGG ACCAGCATCT TAACCCCAAG 
CTGGCTCATC CTGTGGCTCA CCCTCATCCC GACAATAAAA AGACCAAATA TACCGTCATG 
AGGACTCACC TGTTCCAGGC CTCAGCTGCA TATCTGCCGG AACACTTCAT CAGAGTGGGG 
CAGCTGACCA AGCAGGTGGA CATCTTCAGC TGTGGAATTG TATTGGCCGA GGTCCTTACC 
GGCATCCCTG CGATGGACAA GGACCGCAGT CCAGTTTACC TGAAGGATTT GCTTCTCAGT 
GAGATTCCCA ACAGTACTTC TTCAGTCTGC TCCAGGAAGA CCAGCATGGG GAAGGCAGTG 
GTGAAAGAGA TCTGCCAGAG ACATGTGGAG AAGAGGGCAG GGCTGCTGCC TGAGGCCTGT 
GAGGAAGCCT GGGCCACCGC TGTGAGTGTC TGCCTGCGGA GGCGCAATGC CAGCGTGGAG 
GAGGCACGAG TCTCCCTGGC CGGGGTGGAG GAGCAACTCC GAGGGCAGCT GTCCCTTCCC 
TGGAGCAGGG TTTCTGAGGC CACAGGCTCA TCTTCCAATA CCCCGGAGGA AACAGATGAC 
GTTGACAATT CCAGCCTCAG CGTCCCTTCT TTGGTTATGA TGGCATCGTG CCCAGGGGCT 
GCCTCCTCTC CACTCTTCAC GGGACATGGA GCAGCACAGC CATCCACCAG TGGGAGACAG 
GAGGCTGACT CCTCGTCAGA GGCTTGCACA GGCCCACAGA CACCCCAGAA CGCTACAGAG 
ACTTCATGGA AAATTGAGAT CAATGAAGCC AAAAGGAGAC TGATGGAGAA CATCGTACTC 
TACAAAGAAG AGAGACTGGA CAGCAGCGAG CTCTTTGGAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107025.1
CDS	82..1806
Translation	MACYIYQLPSWVLDDLCRNIDTLSEWDWMQFASYVITDLTQLRKIKSMERVQGVSITRELLWWWSMRQATVQQLVDLLCHLELYRAAQIVLSWPIMAGAQRQRPCEMDAPCSLKTDAPDSPQSKYCSTSTSAPKQERLLGLPGDRLFWSEADVVQATEDFDQSHRISEGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFHSLIYPYMANGSLHDRLWAQGNSDMLPWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCSRKTSMGKAVVKEICQRHVEKRAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPEETDDVDNSSLSVPSLVMMASCPGAASSPLFTGHGAAQPSTSGRQEADSSSEACTGPQTPQNATETSWKIEINEAKRRLMENIVLYKEERLDSSELFGP

Target ORF information:

RefSeq Version	NM_001113553.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113553.1

ORF Insert Sequence:

ATGGCTTGCT ACATCTACCA GCTGCCGTCC TGGGTGCTGG ACGACCTGTG CCGCAATATC 
GACACGCTCA GTGAGTGGGA CTGGATGCAG TTCGCTTCCT ACGTGATCAC AGACCTGACA 
CAGCTGAGGA AGATCAAGTC CATGGAGAGG GTCCAGGGGG TGAGCATCAC CCGGGAGCTA 
CTGTGGTGGT GGTCCATGCG GCAGGCCACG GTCCAGCAGC TGGTGGACCT CCTGTGTCAC 
CTGGAACTCT ACCGAGCTGC CCAGATTGTC TTGAGCTGGC CCATCATGGC TGGGGCCCAG 
CGGCAGCGTC CGTGCGAGAT GGATGCCCCT TGTTCCCTGA AAACTGATGC ACCCGACTCT 
CCCCAGTCTA AGTATTGCAG TACTTCCACA TCTGCCCCCA AGCAAGAAAG GCTTTTGGGT 
TTGCCCGGAG ACAGGCTTTT CTGGAGTGAA GCAGATGTCG TCCAAGCAAC TGAGGACTTT 
GACCAAAGCC ACCGAATCAG CGAGGGCACC TTTGCCGATA TCTACCAGGG TCAAAGGAAC 
GGTGTGGCCT TCGCCTTCAA GAAGCTCAGG GAGGTGGCCG GCTCCAGTCC AGGGTCCATG 
GACAGATTCC TACAGGCAGA GATGCAGCTC TGCCTCAGAT GCTGCCACGC GAACGTCCTA 
CCTCTGCTGG GTTTCTGCAC TGGAAGACAG TTCCACAGCC TCATCTACCC CTACATGGCA 
AATGGCTCTC TGCACGACAG ACTCTGGGCT CAGGGCAACT CAGACATGCT GCCCTGGCCA 
CAGCGGGCCA GCATCTGCTC AGGGCTGCTT CTAGCCGTGG AGCACCTGCA TAGCCTGGAC 
ATCATCCACA GCAATGTTAA GAGTGCCAAC GTCTTGCTGG ACCAGCATCT TAACCCCAAG 
CTGGCTCATC CTGTGGCTCA CCCTCATCCC GACAATAAAA AGACCAAATA TACCGTCATG 
AGGACTCACC TGTTCCAGGC CTCAGCTGCA TATCTGCCGG AACACTTCAT CAGAGTGGGG 
CAGCTGACCA AGCAGGTGGA CATCTTCAGC TGTGGAATTG TATTGGCCGA GGTCCTTACC 
GGCATCCCTG CGATGGACAA GGACCGCAGT CCAGTTTACC TGAAGGATTT GCTTCTCAGT 
GAGATTCCCA ACAGTACTTC TTCAGTCTGC TCCAGGAAGA CCAGCATGGG GAAGGCAGTG 
GTGAAAGAGA TCTGCCAGAG ACATGTGGAG AAGAGGGCAG GGCTGCTGCC TGAGGCCTGT 
GAGGAAGCCT GGGCCACCGC TGTGAGTGTC TGCCTGCGGA GGCGCAATGC CAGCGTGGAG 
GAGGCACGAG TCTCCCTGGC CGGGGTGGAG GAGCAACTCC GAGGGCAGCT GTCCCTTCCC 
TGGAGCAGGG TTTCTGAGGC CACAGGCTCA TCTTCCAATA CCCCGGAGGA AACAGATGAC 
GTTGACAATT CCAGCCTCAG CGTCCCTTCT TTGGTTATGA TGGCATCGTG CCCAGGGGCT 
GCCTCCTCTC CACTCTTCAC GGGACATGGA GCAGCACAGC CATCCACCAG TGGGAGACAG 
GAGGCTGACT CCTCGTCAGA GGCTTGCACA GGCCCACAGA CACCCCAGAA CGCTACAGAG 
ACTTCATGGA AAATTGAGAT CAATGAAGCC AAAAGGAGAC TGATGGAGAA CATCGTACTC 
TACAAAGAAG AGAGACTGGA CAGCAGCGAG CTCTTTGGAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak2 ( XM_006505325.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006505388.1 Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.

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CloneID	OMu36744
Clone ID Related Accession (Same CDS sequence)	XM_006505325.3 , XM_006505325.4
Accession Version	XM_006505325.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006505325.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG CCCAGCGGCA GCGTCCGTGC GAGATGGATG CCCCTTGTTC CCTGAAAACT 
GATGCACCCG ACTCTCCCCA GTCTAAGTAT TGCAGTACTT CCACATCTGC CCCCAAGCAA 
GAAAGGCTTT TGGGTTTGCC CGGAGACAGG CTTTTCTGGA GTGAAGCAGA TGTCGTCCAA 
GCAACTGAGG ACTTTGACCA AAGCCACCGA ATCAGCGAGG GCACCTTTGC CGATATCTAC 
CAGGGTCAAA GGAACGGTGT GGCCTTCGCC TTCAAGAAGC TCAGGGAGGT GGCCGGCTCC 
AGTCCAGGGT CCATGGACAG ATTCCTACAG GCAGAGATGC AGCTCTGCCT CAGATGCTGC 
CACGCGAACG TCCTACCTCT GCTGGGTTTC TGCACTGGAA GACAGTTCCA CAGCCTCATC 
TACCCCTACA TGGCAAATGG CTCTCTGCAC GACAGACTCT GGGCTCAGGG CAACTCAGAC 
ATGCTGCCCT GGCCACAGCG GGCCAGCATC TGCTCAGGGC TGCTTCTAGC CGTGGAGCAC 
CTGCATAGCC TGGACATCAT CCACAGCAAT GTTAAGAGTG CCAACGTCTT GCTGGACCAG 
CATCTTAACC CCAAGCTGGC TCATCCTGTG GCTCACCCTC ATCCCGACAA TAAAAAGACC 
AAATATACCG TCATGAGGAC TCACCTGTTC CAGGCCTCAG CTGCATATCT GCCGGAACAC 
TTCATCAGAG TGGGGCAGCT GACCAAGCAG GTGGACATCT TCAGCTGTGG AATTGTATTG 
GCCGAGGTCC TTACCGGCAT CCCTGCGATG GACAAGGACC GCAGTCCAGT TTACCTGAAG 
GATTTGCTTC TCAGTGAGAT TCCCAACAGT ACTTCTTCAG TCTGCTCCAG GAAGACCAGC 
ATGGGGAAGG CAGTGGTGAA AGAGATCTGC CAGAGACATG TGGAGAAGAG GGCAGGGCTG 
CTGCCTGAGG CCTGTGAGGA AGCCTGGGCC ACCGCTGTGA GTGTCTGCCT GCGGAGGCGC 
AATGCCAGCG TGGAGGAGGC ACGAGTCTCC CTGGCCGGGG TGGAGGAGCA ACTCCGAGGG 
CAGCTGTCCC TTCCCTGGAG CAGGGTTTCT GAGGCCACAG GCTCATCTTC CAATACCCCG 
GAGGAAACAG ATGACGTTGA CAATTCCAGC CTCAGCGTCC CTTCTTTGGT TATGATGGCA 
TCGTGCCCAG GGGCTGCCTC CTCTCCACTC TTCACGGGAC ATGGAGCAGC ACAGCCATCC 
ACCAGTGGGA GACAGGAGGC TGACTCCTCG TCAGAGGCTT GCACAGGCCC ACAGACACCC 
CAGAACGCTA CAGAGACTTC ATGGAAAATT GAGATCAATG AAGCCAAAAG GAGACTGATG 
GAGAACATCG TACTCTACAA AGAAGAGAGA CTGGACAGCA GCGAGCTCTT TGGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006505388.1
CDS	354..1793
Translation	MAGAQRQRPCEMDAPCSLKTDAPDSPQSKYCSTSTSAPKQERLLGLPGDRLFWSEADVVQATEDFDQSHRISEGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFHSLIYPYMANGSLHDRLWAQGNSDMLPWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCSRKTSMGKAVVKEICQRHVEKRAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPEETDDVDNSSLSVPSLVMMASCPGAASSPLFTGHGAAQPSTSGRQEADSSSEACTGPQTPQNATETSWKIEINEAKRRLMENIVLYKEERLDSSELFGP

Target ORF information:

RefSeq Version	XM_006505325.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505325.3

ORF Insert Sequence:

ATGGCTGGGG CCCAGCGGCA GCGTCCGTGC GAGATGGATG CCCCTTGTTC CCTGAAAACT 
GATGCACCCG ACTCTCCCCA GTCTAAGTAT TGCAGTACTT CCACATCTGC CCCCAAGCAA 
GAAAGGCTTT TGGGTTTGCC CGGAGACAGG CTTTTCTGGA GTGAAGCAGA TGTCGTCCAA 
GCAACTGAGG ACTTTGACCA AAGCCACCGA ATCAGCGAGG GCACCTTTGC CGATATCTAC 
CAGGGTCAAA GGAACGGTGT GGCCTTCGCC TTCAAGAAGC TCAGGGAGGT GGCCGGCTCC 
AGTCCAGGGT CCATGGACAG ATTCCTACAG GCAGAGATGC AGCTCTGCCT CAGATGCTGC 
CACGCGAACG TCCTACCTCT GCTGGGTTTC TGCACTGGAA GACAGTTCCA CAGCCTCATC 
TACCCCTACA TGGCAAATGG CTCTCTGCAC GACAGACTCT GGGCTCAGGG CAACTCAGAC 
ATGCTGCCCT GGCCACAGCG GGCCAGCATC TGCTCAGGGC TGCTTCTAGC CGTGGAGCAC 
CTGCATAGCC TGGACATCAT CCACAGCAAT GTTAAGAGTG CCAACGTCTT GCTGGACCAG 
CATCTTAACC CCAAGCTGGC TCATCCTGTG GCTCACCCTC ATCCCGACAA TAAAAAGACC 
AAATATACCG TCATGAGGAC TCACCTGTTC CAGGCCTCAG CTGCATATCT GCCGGAACAC 
TTCATCAGAG TGGGGCAGCT GACCAAGCAG GTGGACATCT TCAGCTGTGG AATTGTATTG 
GCCGAGGTCC TTACCGGCAT CCCTGCGATG GACAAGGACC GCAGTCCAGT TTACCTGAAG 
GATTTGCTTC TCAGTGAGAT TCCCAACAGT ACTTCTTCAG TCTGCTCCAG GAAGACCAGC 
ATGGGGAAGG CAGTGGTGAA AGAGATCTGC CAGAGACATG TGGAGAAGAG GGCAGGGCTG 
CTGCCTGAGG CCTGTGAGGA AGCCTGGGCC ACCGCTGTGA GTGTCTGCCT GCGGAGGCGC 
AATGCCAGCG TGGAGGAGGC ACGAGTCTCC CTGGCCGGGG TGGAGGAGCA ACTCCGAGGG 
CAGCTGTCCC TTCCCTGGAG CAGGGTTTCT GAGGCCACAG GCTCATCTTC CAATACCCCG 
GAGGAAACAG ATGACGTTGA CAATTCCAGC CTCAGCGTCC CTTCTTTGGT TATGATGGCA 
TCGTGCCCAG GGGCTGCCTC CTCTCCACTC TTCACGGGAC ATGGAGCAGC ACAGCCATCC 
ACCAGTGGGA GACAGGAGGC TGACTCCTCG TCAGAGGCTT GCACAGGCCC ACAGACACCC 
CAGAACGCTA CAGAGACTTC ATGGAAAATT GAGATCAATG AAGCCAAAAG GAGACTGATG 
GAGAACATCG TACTCTACAA AGAAGAGAGA CTGGACAGCA GCGAGCTCTT TGGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak2 ( XM_006505325.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006505388.1 Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.

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CloneID	OMu36744
Clone ID Related Accession (Same CDS sequence)	XM_006505325.3 , XM_006505325.4
Accession Version	XM_006505325.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interleukin-1 receptor-associated kinase-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006505325.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG CCCAGCGGCA GCGTCCGTGC GAGATGGATG CCCCTTGTTC CCTGAAAACT 
GATGCACCCG ACTCTCCCCA GTCTAAGTAT TGCAGTACTT CCACATCTGC CCCCAAGCAA 
GAAAGGCTTT TGGGTTTGCC CGGAGACAGG CTTTTCTGGA GTGAAGCAGA TGTCGTCCAA 
GCAACTGAGG ACTTTGACCA AAGCCACCGA ATCAGCGAGG GCACCTTTGC CGATATCTAC 
CAGGGTCAAA GGAACGGTGT GGCCTTCGCC TTCAAGAAGC TCAGGGAGGT GGCCGGCTCC 
AGTCCAGGGT CCATGGACAG ATTCCTACAG GCAGAGATGC AGCTCTGCCT CAGATGCTGC 
CACGCGAACG TCCTACCTCT GCTGGGTTTC TGCACTGGAA GACAGTTCCA CAGCCTCATC 
TACCCCTACA TGGCAAATGG CTCTCTGCAC GACAGACTCT GGGCTCAGGG CAACTCAGAC 
ATGCTGCCCT GGCCACAGCG GGCCAGCATC TGCTCAGGGC TGCTTCTAGC CGTGGAGCAC 
CTGCATAGCC TGGACATCAT CCACAGCAAT GTTAAGAGTG CCAACGTCTT GCTGGACCAG 
CATCTTAACC CCAAGCTGGC TCATCCTGTG GCTCACCCTC ATCCCGACAA TAAAAAGACC 
AAATATACCG TCATGAGGAC TCACCTGTTC CAGGCCTCAG CTGCATATCT GCCGGAACAC 
TTCATCAGAG TGGGGCAGCT GACCAAGCAG GTGGACATCT TCAGCTGTGG AATTGTATTG 
GCCGAGGTCC TTACCGGCAT CCCTGCGATG GACAAGGACC GCAGTCCAGT TTACCTGAAG 
GATTTGCTTC TCAGTGAGAT TCCCAACAGT ACTTCTTCAG TCTGCTCCAG GAAGACCAGC 
ATGGGGAAGG CAGTGGTGAA AGAGATCTGC CAGAGACATG TGGAGAAGAG GGCAGGGCTG 
CTGCCTGAGG CCTGTGAGGA AGCCTGGGCC ACCGCTGTGA GTGTCTGCCT GCGGAGGCGC 
AATGCCAGCG TGGAGGAGGC ACGAGTCTCC CTGGCCGGGG TGGAGGAGCA ACTCCGAGGG 
CAGCTGTCCC TTCCCTGGAG CAGGGTTTCT GAGGCCACAG GCTCATCTTC CAATACCCCG 
GAGGAAACAG ATGACGTTGA CAATTCCAGC CTCAGCGTCC CTTCTTTGGT TATGATGGCA 
TCGTGCCCAG GGGCTGCCTC CTCTCCACTC TTCACGGGAC ATGGAGCAGC ACAGCCATCC 
ACCAGTGGGA GACAGGAGGC TGACTCCTCG TCAGAGGCTT GCACAGGCCC ACAGACACCC 
CAGAACGCTA CAGAGACTTC ATGGAAAATT GAGATCAATG AAGCCAAAAG GAGACTGATG 
GAGAACATCG TACTCTACAA AGAAGAGAGA CTGGACAGCA GCGAGCTCTT TGGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006505388.1
CDS	366..1805
Translation	MAGAQRQRPCEMDAPCSLKTDAPDSPQSKYCSTSTSAPKQERLLGLPGDRLFWSEADVVQATEDFDQSHRISEGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFHSLIYPYMANGSLHDRLWAQGNSDMLPWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCSRKTSMGKAVVKEICQRHVEKRAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPEETDDVDNSSLSVPSLVMMASCPGAASSPLFTGHGAAQPSTSGRQEADSSSEACTGPQTPQNATETSWKIEINEAKRRLMENIVLYKEERLDSSELFGP

Target ORF information:

RefSeq Version	XM_006505325.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505325.4

ORF Insert Sequence:

ATGGCTGGGG CCCAGCGGCA GCGTCCGTGC GAGATGGATG CCCCTTGTTC CCTGAAAACT 
GATGCACCCG ACTCTCCCCA GTCTAAGTAT TGCAGTACTT CCACATCTGC CCCCAAGCAA 
GAAAGGCTTT TGGGTTTGCC CGGAGACAGG CTTTTCTGGA GTGAAGCAGA TGTCGTCCAA 
GCAACTGAGG ACTTTGACCA AAGCCACCGA ATCAGCGAGG GCACCTTTGC CGATATCTAC 
CAGGGTCAAA GGAACGGTGT GGCCTTCGCC TTCAAGAAGC TCAGGGAGGT GGCCGGCTCC 
AGTCCAGGGT CCATGGACAG ATTCCTACAG GCAGAGATGC AGCTCTGCCT CAGATGCTGC 
CACGCGAACG TCCTACCTCT GCTGGGTTTC TGCACTGGAA GACAGTTCCA CAGCCTCATC 
TACCCCTACA TGGCAAATGG CTCTCTGCAC GACAGACTCT GGGCTCAGGG CAACTCAGAC 
ATGCTGCCCT GGCCACAGCG GGCCAGCATC TGCTCAGGGC TGCTTCTAGC CGTGGAGCAC 
CTGCATAGCC TGGACATCAT CCACAGCAAT GTTAAGAGTG CCAACGTCTT GCTGGACCAG 
CATCTTAACC CCAAGCTGGC TCATCCTGTG GCTCACCCTC ATCCCGACAA TAAAAAGACC 
AAATATACCG TCATGAGGAC TCACCTGTTC CAGGCCTCAG CTGCATATCT GCCGGAACAC 
TTCATCAGAG TGGGGCAGCT GACCAAGCAG GTGGACATCT TCAGCTGTGG AATTGTATTG 
GCCGAGGTCC TTACCGGCAT CCCTGCGATG GACAAGGACC GCAGTCCAGT TTACCTGAAG 
GATTTGCTTC TCAGTGAGAT TCCCAACAGT ACTTCTTCAG TCTGCTCCAG GAAGACCAGC 
ATGGGGAAGG CAGTGGTGAA AGAGATCTGC CAGAGACATG TGGAGAAGAG GGCAGGGCTG 
CTGCCTGAGG CCTGTGAGGA AGCCTGGGCC ACCGCTGTGA GTGTCTGCCT GCGGAGGCGC 
AATGCCAGCG TGGAGGAGGC ACGAGTCTCC CTGGCCGGGG TGGAGGAGCA ACTCCGAGGG 
CAGCTGTCCC TTCCCTGGAG CAGGGTTTCT GAGGCCACAG GCTCATCTTC CAATACCCCG 
GAGGAAACAG ATGACGTTGA CAATTCCAGC CTCAGCGTCC CTTCTTTGGT TATGATGGCA 
TCGTGCCCAG GGGCTGCCTC CTCTCCACTC TTCACGGGAC ATGGAGCAGC ACAGCCATCC 
ACCAGTGGGA GACAGGAGGC TGACTCCTCG TCAGAGGCTT GCACAGGCCC ACAGACACCC 
CAGAACGCTA CAGAGACTTC ATGGAAAATT GAGATCAATG AAGCCAAAAG GAGACTGATG 
GAGAACATCG TACTCTACAA AGAAGAGAGA CTGGACAGCA GCGAGCTCTT TGGACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.
eLife6(2017 Oct)
Zhou H,Bulek K,Li X,Herjan T,Yu M,Qian W,Wang H,Zhou G,Chen X,Yang H,Hong L,Zhao J,Qin L,Fukuda K,Flotho A,Gao J,Dongre A,Carman JA,Kang Z,Su B,Kern TS,Smith JD,Hamilton TA,Melchior F,Fox PL,Li X

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling.
Cell reports19(13)2853-2866(2017 Jun)
Mertins P,Przybylski D,Yosef N,Qiao J,Clauser K,Raychowdhury R,Eisenhaure TM,Maritzen T,Haucke V,Satoh T,Akira S,Carr SA,Regev A,Hacohen N,Chevrier N

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Science signaling9(409)ra3(2016 Jan)
Sun J,Li N,Oh KS,Dutta B,Vayttaden SJ,Lin B,Ebert TS,De Nardo D,Davis J,Bagirzadeh R,Lounsbury NW,Pasare C,Latz E,Hornung V,Fraser ID

The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.
Science signaling6(295)ra87(2013 Oct)
Ma J,Bang BR,Lu J,Eun SY,Otsuka M,Croft M,Tobias P,Han J,Takeuchi O,Akira S,Karin M,Yagita H,Kang YJ

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Irak2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム