Gene Symbol | CXCR4 |
Entrez Gene ID | 707329 |
Full Name | C-X-C motif chemokine receptor 4 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » CXCR4 cDNA ORF clone
Gene Symbol | CXCR4 |
Entrez Gene ID | 707329 |
Full Name | C-X-C motif chemokine receptor 4 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001042645.1 | NP_001036110.1 | C-X-C chemokine receptor type 4 |
Gallus gallus (chicken) | CXCR4 | NP_989948.2 |
Danio rerio (zebrafish) | cxcr4a | NP_571957.2 |
Danio rerio (zebrafish) | cxcr4b | NP_571909.1 |
Pan troglodytes (chimpanzee) | CXCR4 | NP_001009047.1 |
Mus musculus (house mouse) | Cxcr4 | NP_034041.2 |
Rattus norvegicus (Norway rat) | Cxcr4 | NP_071541.2 |
Xenopus tropicalis (tropical clawed frog) | cxcr4 | NP_001090831.1 |
Homo sapiens (human) | CXCR4 | NP_003458.1 |
CXCR4 | NP_001036110.1 | |
Canis lupus familiaris (dog) | CXCR4 | NP_001041491.1 |
Bos taurus (cattle) | CXCR4 | NP_776726.1 |
TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression.
Feng YF, Yuan F, Guo H, Wu WZ
Molecular and cellular biochemistry397(1-2)131-8(2014 Dec)
CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells.
Jin J, Zhao WC, Yuan F
Ophthalmic research50(1)6-12(2013)
Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells.
Li F, Xu H, Zeng Y, Yin ZQ
Current eye research37(6)540-8(2012 Jun)
Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus.
Ho SH, Trunova N, Gettie A, Blanchard J, Cheng-Mayer C
Journal of virology82(11)5653-6(2008 Jun)
New widespread CXCR4 allele in rhesus macaques does not predict subspecies or clinical evolution.
Pr?tet JL, Guillet JG, Butor C
AIDS research and human retroviruses14(7)639-41(1998 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The increased CXCR4 and CXCR7 expression resulted in increased SDF-1-induced RF/6A cell migration and tube formation.
Title: TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression.
The CXCR7/CXCR4/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
Title: CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells.
These findings suggest that FBLN5 may interfere with choroidal neovascularization by downregulating VEGF, CXCR4, and TGFB1 expression and inhibiting choroidl endothelial cell proliferation.
Title: Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells.
Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively
Title: Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus.
The following CXCR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb01495 | |
Clone ID Related Accession (Same CDS sequence) | NM_001042645.1 | |
Accession Version | NM_001042645.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | C-X-C chemokine receptor type 4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF001928.1. On Aug 3, 2006 this sequence version replaced XR_011665.1. ##Evidence-Data-START## Transcript exon combination :: AF001928.1, CB554428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688367 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGGGGA TCAGTATATA CACTTCAGAT AACTACACCG AGGAAATGGG CTCAGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001036110.1 |
CDS | 29..1087 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001042645.1 |
1 | ATGGAGGGGA TCAGTATATA CACTTCAGAT AACTACACCG AGGAAATGGG CTCAGGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression. |
CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells. |
Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells. |
Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus. |
New widespread CXCR4 allele in rhesus macaques does not predict subspecies or clinical evolution. |