TRIP4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIP4
Entrez Gene ID	9325
Full Name	thyroid hormone receptor interactor 4
Synonyms	ASC-1,ASC1,HsT17391,MDCDC,SMABF1,ZC2HC5
General protein information	Preferred Names thyroid hormone receptor interactor 4 Names activating signal cointegrator 1 TR-interacting protein 4 TRIP-4 thyroid receptor-interacting protein 4 zinc finger, C2HC5-type
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.31
Summary	This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016].
Disorder MIM:	604501
Disorder Html:	Spinal muscular atrophy with congenital bone fractures 1, 616866 (3); ?Muscular dystrophy, congenital, Davignon-Chauveau type, 617066 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_016213.5	NP_057297.2	activating signal cointegrator 1 isoform 1
NM_001321924.1	NP_001308853.1	activating signal cointegrator 1 isoform 2
NM_001321924.2	NP_001308853.1	activating signal cointegrator 1 isoform 2
NM_016213.4	NP_057297.2	activating signal cointegrator 1 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TRIP4	XP_510472.2
Danio rerio (zebrafish)	trip4	NP_001071043.2
Drosophila melanogaster (fruit fly)	CG11710	NP_608393.1
Bos taurus (cattle)	TRIP4	NP_001039816.1
Rattus norvegicus (Norway rat)	Trip4	NP_001128453.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000554	XP_310529.5
Caenorhabditis elegans (roundworm)	asc-1	NP_497100.1
Homo sapiens (human)	TRIP4	NP_057297.2
Canis lupus familiaris (dog)	TRIP4	XP_535513.2
	TRIP4	XP_001107836.1
Mus musculus (house mouse)	Trip4	NP_062771.2
Gallus gallus (chicken)	TRIP4	XP_004943672.1

Gene Ontology
Bibliography

Related articles in PubMed

The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.
Hao J, Xu H, Luo M, Yu W, Chen M, Liao Y, Zhang C, Zhao X, Jiang W, Hou S, Feng X, Zou K, Chen Y, Huang W, Guo W, Kang L, Deng W
The Journal of investigative dermatology138(1)159-170(2018 Jan)

The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease.
Davignon L, Chauveau C, Julien C, Dill C, Duband-Goulet I, Cabet E, Buendia B, Lilienbaum A, Rendu J, Minot MC, Guichet A, Allamand V, Vadrot N, Faur? J, Odent S, Lazaro L, Leroy JP, Marcorelles P, Dubourg O, Ferreiro A
Human molecular genetics25(8)1559-73(2016 Apr)

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures.
Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Sch?neborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, H?bner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M
American journal of human genetics98(3)473-489(2016 Mar)

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Yoo HM, Kang SH, Kim JY, Lee JE, Seong MW, Lee SW, Ka SH, Sou YS, Komatsu M, Tanaka K, Lee ST, Noh DY, Baek SH, Jeon YJ, Chung CH
Molecular cell56(2)261-74(2014 Oct)

Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.
Ruiz A, Heilmann S, Becker T, Hern?ndez I, Wagner H, Thelen M, Maule?n A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodr?guez O, Ortega G, Dominguez MA, , Mayeux R, Haines JL, Pericak-Vance MA, Farrer LA, Schellenberg GD, Chouraki V, Launer LJ, van Duijn C, Seshadri S, Ant?nez C, Breteler MM, Serrano-R?os M, Jessen F, T?rraga L, N?then MM, Maier W, Boada M, Ram?rez A
Translational psychiatry4e358(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Reports reveal the first TRIP4 mutation defining a novel form of congenital muscle disease and establish the importance of ASC-1 in human skeletal muscle, identify transcriptional co-regulation as novel pathophysiological pathway, define ASC-1 as a regulator of late myogenic differentiation and suggest defects in myotube growth as a novel myopathic mechanism.
Title: The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease.

GWAS in a large Spanish sample identifies TRIP4 (rs74615166) as a significant locus for Alzheimer's disease risk.
Title: Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.

Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1.
Title: Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1.

The following TRIP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26974	NM_016213.5 Latest version!	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu48670	NM_001321924.2 Latest version!	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu48670	NM_001321924.1	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu26974	NM_016213.4	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIP4 ( NM_016213.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057297.2 Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26974
Clone ID Related Accession (Same CDS sequence)	NM_016213.5 , NM_016213.4
Accession Version	NM_016213.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	activating signal cointegrator 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG166305.1, AK314319.1 and BC012448.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_016213.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012448.1, SRR1660803.207503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261884.8/ ENSP00000261884.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGG CTGGGGCGGT GTCCGGGGAG CCGCTGGTGC ACTGGTGCAC CCAGCAGTTG 
CGGAAGACTT TCGGCCTGGA TGTCAGCGAG GAGATCATTC AGTACGTTTT GTCAATTGAG 
AGTGCTGAAG AGATACGAGA ATATGTTACT GATCTCCTCC AGGGAAATGA AGGCAAAAAA 
GGTCAATTCA TAGAAGAACT TATAACCAAA TGGCAAAAGA ATGATCAGGA GTTGATTTCG 
GATCCTTTGC AGCAGTGCTT CAAAAAAGAT GAAATTTTAG ATGGGCAGAA ATCAGGCGAC 
CATCTAAAGC GGGGTAGGAA GAAAGGGAGA AACAGACAGG AAGTTCCTGC ATTTACTGAA 
CCTGACACGA CTGCAGAGGT TAAAACACCT TTTGATTTGG CCAAGGCACA AGAGAACAGC 
AACTCCGTAA AGAAGAAGAC AAAGTTTGTC AATTTATACA CAAGAGAGGG ACAGGACAGG 
CTTGCAGTCC TGCTCCCTGG TCGTCACCCT TGTGATTGCC TGGGCCAGAA GCACAAGCTC 
ATCAATAACT GTCTGATCTG TGGGCGCATT GTCTGTGAAC AAGAAGGCTC AGGCCCTTGC 
TTATTCTGTG GCACTCTGGT GTGTACTCAT GAGGAACAAG ATATTTTACA GCGTGACTCA 
AACAAGAGCC AGAAACTGCT AAAGAAACTC ATGTCAGGAG TGGAGAATTC TGGAAAGGTG 
GACATCTCTA CCAAGGACCT TCTTCCTCAT CAAGAATTGC GAATTAAGTC TGGTCTGGAG 
AAGGCTATCA AGCATAAAGA CAAACTGTTA GAGTTTGACA GAACTAGTAT TCGAAGGACC 
CAAGTCATTG ATGATGAGTC AGATTACTTT GCCAGTGATT CTAACCAATG GTTGTCCAAA 
CTTGAGCGGG AAACCTTGCA GAAGCGAGAG GAGGAGCTGA GAGAACTTCG ACACGCCTCT 
CGACTTTCTA AGAAGGTCAC CATTGACTTT GCAGGAAGGA AGATCCTGGA AGAAGAAAAT 
TCACTAGCAG AGTATCATAG CAGACTAGAT GAGACAATAC AGGCCATTGC CAATGGAACC 
TTGAACCAGC CACTGACCAA ATTGGATAGA TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA 
AATCCCAACA TGTACCAGTC CCCTCCCCAG TGGGTTGACC ACACAGGTGC AGCCTCACAG 
AAGAAGGCTT TCCGTTCTTC AGGATTTGGA CTAGAGTTCA ACTCATTTCA GCACCAGTTG 
CGAATCCAGG ATCAAGAATT TCAGGAAGGC TTTGATGGTG GCTGGTGCCT CTCTGTACAT 
CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC 
ACCCCCCACA GAGGACGACT TTGGATAGCA GCCACAGCTA AAAAACCCTC CCCTCAAGAA 
GTCTCAGAAC TCCAGGCTAC ATATCGTCTT CTTCGTGGGA AAGATGTGGA ATTTCCTAAT 
GACTATCCGT CAGGTTGTCT TCTGGGCTGT GTGGACCTAA TTGACTGCTT GTCCCAGAAG 
CAATTTAAGG AGCAGTTTCC AGACATCAGT CAAGAGTCTG ATTCTCCATT TGTTTTCATC 
TGCAAAAATC CTCAGGAAAT GGTTGTGAAG TTTCCTATTA AAGGAAATCC AAAAATCTGG 
AAATTGGATT CCAAGATCCA TCAAGGAGCA AAGAAGGGGT TAATGAAGCA GAATAAAGCT 
GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057297.2
CDS	29..1774
Translation	MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKKGQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTEPDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV

Target ORF information:

RefSeq Version	NM_016213.5
Organism	Homo sapiens(human)
Definition	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016213.5

ORF Insert Sequence:

ATGGCGGTGG CTGGGGCGGT GTCCGGGGAG CCGCTGGTGC ACTGGTGCAC CCAGCAGTTG 
CGGAAGACTT TCGGCCTGGA TGTCAGCGAG GAGATCATTC AGTACGTTTT GTCAATTGAG 
AGTGCTGAAG AGATACGAGA ATATGTTACT GATCTCCTCC AGGGAAATGA AGGCAAAAAA 
GGTCAATTCA TAGAAGAACT TATAACCAAA TGGCAAAAGA ATGATCAGGA GTTGATTTCG 
GATCCTTTGC AGCAGTGCTT CAAAAAAGAT GAAATTTTAG ATGGGCAGAA ATCAGGCGAC 
CATCTAAAGC GGGGTAGGAA GAAAGGGAGA AACAGACAGG AAGTTCCTGC ATTTACTGAA 
CCTGACACGA CTGCAGAGGT TAAAACACCT TTTGATTTGG CCAAGGCACA AGAGAACAGC 
AACTCCGTAA AGAAGAAGAC AAAGTTTGTC AATTTATACA CAAGAGAGGG ACAGGACAGG 
CTTGCAGTCC TGCTCCCTGG TCGTCACCCT TGTGATTGCC TGGGCCAGAA GCACAAGCTC 
ATCAATAACT GTCTGATCTG TGGGCGCATT GTCTGTGAAC AAGAAGGCTC AGGCCCTTGC 
TTATTCTGTG GCACTCTGGT GTGTACTCAT GAGGAACAAG ATATTTTACA GCGTGACTCA 
AACAAGAGCC AGAAACTGCT AAAGAAACTC ATGTCAGGAG TGGAGAATTC TGGAAAGGTG 
GACATCTCTA CCAAGGACCT TCTTCCTCAT CAAGAATTGC GAATTAAGTC TGGTCTGGAG 
AAGGCTATCA AGCATAAAGA CAAACTGTTA GAGTTTGACA GAACTAGTAT TCGAAGGACC 
CAAGTCATTG ATGATGAGTC AGATTACTTT GCCAGTGATT CTAACCAATG GTTGTCCAAA 
CTTGAGCGGG AAACCTTGCA GAAGCGAGAG GAGGAGCTGA GAGAACTTCG ACACGCCTCT 
CGACTTTCTA AGAAGGTCAC CATTGACTTT GCAGGAAGGA AGATCCTGGA AGAAGAAAAT 
TCACTAGCAG AGTATCATAG CAGACTAGAT GAGACAATAC AGGCCATTGC CAATGGAACC 
TTGAACCAGC CACTGACCAA ATTGGATAGA TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA 
AATCCCAACA TGTACCAGTC CCCTCCCCAG TGGGTTGACC ACACAGGTGC AGCCTCACAG 
AAGAAGGCTT TCCGTTCTTC AGGATTTGGA CTAGAGTTCA ACTCATTTCA GCACCAGTTG 
CGAATCCAGG ATCAAGAATT TCAGGAAGGC TTTGATGGTG GCTGGTGCCT CTCTGTACAT 
CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC 
ACCCCCCACA GAGGACGACT TTGGATAGCA GCCACAGCTA AAAAACCCTC CCCTCAAGAA 
GTCTCAGAAC TCCAGGCTAC ATATCGTCTT CTTCGTGGGA AAGATGTGGA ATTTCCTAAT 
GACTATCCGT CAGGTTGTCT TCTGGGCTGT GTGGACCTAA TTGACTGCTT GTCCCAGAAG 
CAATTTAAGG AGCAGTTTCC AGACATCAGT CAAGAGTCTG ATTCTCCATT TGTTTTCATC 
TGCAAAAATC CTCAGGAAAT GGTTGTGAAG TTTCCTATTA AAGGAAATCC AAAAATCTGG 
AAATTGGATT CCAAGATCCA TCAAGGAGCA AAGAAGGGGT TAATGAAGCA GAATAAAGCT 
GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIP4 ( NM_016213.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057297.2 Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26974
Clone ID Related Accession (Same CDS sequence)	NM_016213.5 , NM_016213.4
Accession Version	NM_016213.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	activating signal cointegrator 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG166305.1, AK314319.1 and BC012448.1. This sequence is a reference standard in the RefSeqGene project. On Jul 29, 2010 this sequence version replaced NM_016213.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012448.1, SRR1803615.258327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGG CTGGGGCGGT GTCCGGGGAG CCGCTGGTGC ACTGGTGCAC CCAGCAGTTG 
CGGAAGACTT TCGGCCTGGA TGTCAGCGAG GAGATCATTC AGTACGTTTT GTCAATTGAG 
AGTGCTGAAG AGATACGAGA ATATGTTACT GATCTCCTCC AGGGAAATGA AGGCAAAAAA 
GGTCAATTCA TAGAAGAACT TATAACCAAA TGGCAAAAGA ATGATCAGGA GTTGATTTCG 
GATCCTTTGC AGCAGTGCTT CAAAAAAGAT GAAATTTTAG ATGGGCAGAA ATCAGGCGAC 
CATCTAAAGC GGGGTAGGAA GAAAGGGAGA AACAGACAGG AAGTTCCTGC ATTTACTGAA 
CCTGACACGA CTGCAGAGGT TAAAACACCT TTTGATTTGG CCAAGGCACA AGAGAACAGC 
AACTCCGTAA AGAAGAAGAC AAAGTTTGTC AATTTATACA CAAGAGAGGG ACAGGACAGG 
CTTGCAGTCC TGCTCCCTGG TCGTCACCCT TGTGATTGCC TGGGCCAGAA GCACAAGCTC 
ATCAATAACT GTCTGATCTG TGGGCGCATT GTCTGTGAAC AAGAAGGCTC AGGCCCTTGC 
TTATTCTGTG GCACTCTGGT GTGTACTCAT GAGGAACAAG ATATTTTACA GCGTGACTCA 
AACAAGAGCC AGAAACTGCT AAAGAAACTC ATGTCAGGAG TGGAGAATTC TGGAAAGGTG 
GACATCTCTA CCAAGGACCT TCTTCCTCAT CAAGAATTGC GAATTAAGTC TGGTCTGGAG 
AAGGCTATCA AGCATAAAGA CAAACTGTTA GAGTTTGACA GAACTAGTAT TCGAAGGACC 
CAAGTCATTG ATGATGAGTC AGATTACTTT GCCAGTGATT CTAACCAATG GTTGTCCAAA 
CTTGAGCGGG AAACCTTGCA GAAGCGAGAG GAGGAGCTGA GAGAACTTCG ACACGCCTCT 
CGACTTTCTA AGAAGGTCAC CATTGACTTT GCAGGAAGGA AGATCCTGGA AGAAGAAAAT 
TCACTAGCAG AGTATCATAG CAGACTAGAT GAGACAATAC AGGCCATTGC CAATGGAACC 
TTGAACCAGC CACTGACCAA ATTGGATAGA TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA 
AATCCCAACA TGTACCAGTC CCCTCCCCAG TGGGTTGACC ACACAGGTGC AGCCTCACAG 
AAGAAGGCTT TCCGTTCTTC AGGATTTGGA CTAGAGTTCA ACTCATTTCA GCACCAGTTG 
CGAATCCAGG ATCAAGAATT TCAGGAAGGC TTTGATGGTG GCTGGTGCCT CTCTGTACAT 
CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC 
ACCCCCCACA GAGGACGACT TTGGATAGCA GCCACAGCTA AAAAACCCTC CCCTCAAGAA 
GTCTCAGAAC TCCAGGCTAC ATATCGTCTT CTTCGTGGGA AAGATGTGGA ATTTCCTAAT 
GACTATCCGT CAGGTTGTCT TCTGGGCTGT GTGGACCTAA TTGACTGCTT GTCCCAGAAG 
CAATTTAAGG AGCAGTTTCC AGACATCAGT CAAGAGTCTG ATTCTCCATT TGTTTTCATC 
TGCAAAAATC CTCAGGAAAT GGTTGTGAAG TTTCCTATTA AAGGAAATCC AAAAATCTGG 
AAATTGGATT CCAAGATCCA TCAAGGAGCA AAGAAGGGGT TAATGAAGCA GAATAAAGCT 
GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057297.2
CDS	61..1806
Translation	MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKKGQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTEPDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV

Target ORF information:

RefSeq Version	NM_016213.4
Organism	Homo sapiens(human)
Definition	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016213.4

ORF Insert Sequence:

ATGGCGGTGG CTGGGGCGGT GTCCGGGGAG CCGCTGGTGC ACTGGTGCAC CCAGCAGTTG 
CGGAAGACTT TCGGCCTGGA TGTCAGCGAG GAGATCATTC AGTACGTTTT GTCAATTGAG 
AGTGCTGAAG AGATACGAGA ATATGTTACT GATCTCCTCC AGGGAAATGA AGGCAAAAAA 
GGTCAATTCA TAGAAGAACT TATAACCAAA TGGCAAAAGA ATGATCAGGA GTTGATTTCG 
GATCCTTTGC AGCAGTGCTT CAAAAAAGAT GAAATTTTAG ATGGGCAGAA ATCAGGCGAC 
CATCTAAAGC GGGGTAGGAA GAAAGGGAGA AACAGACAGG AAGTTCCTGC ATTTACTGAA 
CCTGACACGA CTGCAGAGGT TAAAACACCT TTTGATTTGG CCAAGGCACA AGAGAACAGC 
AACTCCGTAA AGAAGAAGAC AAAGTTTGTC AATTTATACA CAAGAGAGGG ACAGGACAGG 
CTTGCAGTCC TGCTCCCTGG TCGTCACCCT TGTGATTGCC TGGGCCAGAA GCACAAGCTC 
ATCAATAACT GTCTGATCTG TGGGCGCATT GTCTGTGAAC AAGAAGGCTC AGGCCCTTGC 
TTATTCTGTG GCACTCTGGT GTGTACTCAT GAGGAACAAG ATATTTTACA GCGTGACTCA 
AACAAGAGCC AGAAACTGCT AAAGAAACTC ATGTCAGGAG TGGAGAATTC TGGAAAGGTG 
GACATCTCTA CCAAGGACCT TCTTCCTCAT CAAGAATTGC GAATTAAGTC TGGTCTGGAG 
AAGGCTATCA AGCATAAAGA CAAACTGTTA GAGTTTGACA GAACTAGTAT TCGAAGGACC 
CAAGTCATTG ATGATGAGTC AGATTACTTT GCCAGTGATT CTAACCAATG GTTGTCCAAA 
CTTGAGCGGG AAACCTTGCA GAAGCGAGAG GAGGAGCTGA GAGAACTTCG ACACGCCTCT 
CGACTTTCTA AGAAGGTCAC CATTGACTTT GCAGGAAGGA AGATCCTGGA AGAAGAAAAT 
TCACTAGCAG AGTATCATAG CAGACTAGAT GAGACAATAC AGGCCATTGC CAATGGAACC 
TTGAACCAGC CACTGACCAA ATTGGATAGA TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA 
AATCCCAACA TGTACCAGTC CCCTCCCCAG TGGGTTGACC ACACAGGTGC AGCCTCACAG 
AAGAAGGCTT TCCGTTCTTC AGGATTTGGA CTAGAGTTCA ACTCATTTCA GCACCAGTTG 
CGAATCCAGG ATCAAGAATT TCAGGAAGGC TTTGATGGTG GCTGGTGCCT CTCTGTACAT 
CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC 
ACCCCCCACA GAGGACGACT TTGGATAGCA GCCACAGCTA AAAAACCCTC CCCTCAAGAA 
GTCTCAGAAC TCCAGGCTAC ATATCGTCTT CTTCGTGGGA AAGATGTGGA ATTTCCTAAT 
GACTATCCGT CAGGTTGTCT TCTGGGCTGT GTGGACCTAA TTGACTGCTT GTCCCAGAAG 
CAATTTAAGG AGCAGTTTCC AGACATCAGT CAAGAGTCTG ATTCTCCATT TGTTTTCATC 
TGCAAAAATC CTCAGGAAAT GGTTGTGAAG TTTCCTATTA AAGGAAATCC AAAAATCTGG 
AAATTGGATT CCAAGATCCA TCAAGGAGCA AAGAAGGGGT TAATGAAGCA GAATAAAGCT 
GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIP4 ( NM_001321924.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308853.1 Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.

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CloneID	OHu48670
Clone ID Related Accession (Same CDS sequence)	NM_001321924.1 , NM_001321924.2
Accession Version	NM_001321924.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	activating signal cointegrator 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA712387.1, AK314319.1 and BC012448.1. On Apr 1, 2016 this sequence version replaced XM_005254789.1. Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal exon, which results in translation initiation at an in-frame downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.16601.1, SRR1803612.54553.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGAG TGGAGAATTC TGGAAAGGTG GACATCTCTA CCAAGGACCT TCTTCCTCAT 
CAAGAATTGC GAATTAAGTC TGGTCTGGAG AAGGCTATCA AGCATAAAGA CAAACTGTTA 
GAGTTTGACA GAACTAGTAT TCGAAGGACC CAAGTCATTG ATGATGAGTC AGATTACTTT 
GCCAGTGATT CTAACCAATG GTTGTCCAAA CTTGAGCGGG AAACCTTGCA GAAGCGAGAG 
GAGGAGCTGA GAGAACTTCG ACACGCCTCT CGACTTTCTA AGAAGGTCAC CATTGACTTT 
GCAGGAAGGA AGATCCTGGA AGAAGAAAAT TCACTAGCAG AGTATCATAG CAGACTAGAT 
GAGACAATAC AGGCCATTGC CAATGGAACC TTGAACCAGC CACTGACCAA ATTGGATAGA 
TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA AATCCCAACA TGTACCAGTC CCCTCCCCAG 
TGGGTTGACC ACACAGGTGC AGCCTCACAG AAGAAGGCTT TCCGTTCTTC AGGATTTGGA 
CTAGAGTTCA ACTCATTTCA GCACCAGTTG CGAATCCAGG ATCAAGAATT TCAGGAAGGC 
TTTGATGGTG GCTGGTGCCT CTCTGTACAT CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG 
ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC ACCCCCCACA GAGGACGACT TTGGATAGCA 
GCCACAGCTA AAAAACCCTC CCCTCAAGAA GTCTCAGAAC TCCAGGCTAC ATATCGTCTT 
CTTCGTGGGA AAGATGTGGA ATTTCCTAAT GACTATCCGT CAGGTTGTCT TCTGGGCTGT 
GTGGACCTAA TTGACTGCTT GTCCCAGAAG CAATTTAAGG AGCAGTTTCC AGACATCAGT 
CAAGAGTCTG ATTCTCCATT TGTTTTCATC TGCAAAAATC CTCAGGAAAT GGTTGTGAAG 
TTTCCTATTA AAGGAAATCC AAAAATCTGG AAATTGGATT CCAAGATCCA TCAAGGAGCA 
AAGAAGGGGT TAATGAAGCA GAATAAAGCT GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308853.1
CDS	829..1884
Translation	MSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV

Target ORF information:

RefSeq Version	NM_001321924.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321924.1

ORF Insert Sequence:

ATGTCAGGAG TGGAGAATTC TGGAAAGGTG GACATCTCTA CCAAGGACCT TCTTCCTCAT 
CAAGAATTGC GAATTAAGTC TGGTCTGGAG AAGGCTATCA AGCATAAAGA CAAACTGTTA 
GAGTTTGACA GAACTAGTAT TCGAAGGACC CAAGTCATTG ATGATGAGTC AGATTACTTT 
GCCAGTGATT CTAACCAATG GTTGTCCAAA CTTGAGCGGG AAACCTTGCA GAAGCGAGAG 
GAGGAGCTGA GAGAACTTCG ACACGCCTCT CGACTTTCTA AGAAGGTCAC CATTGACTTT 
GCAGGAAGGA AGATCCTGGA AGAAGAAAAT TCACTAGCAG AGTATCATAG CAGACTAGAT 
GAGACAATAC AGGCCATTGC CAATGGAACC TTGAACCAGC CACTGACCAA ATTGGATAGA 
TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA AATCCCAACA TGTACCAGTC CCCTCCCCAG 
TGGGTTGACC ACACAGGTGC AGCCTCACAG AAGAAGGCTT TCCGTTCTTC AGGATTTGGA 
CTAGAGTTCA ACTCATTTCA GCACCAGTTG CGAATCCAGG ATCAAGAATT TCAGGAAGGC 
TTTGATGGTG GCTGGTGCCT CTCTGTACAT CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG 
ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC ACCCCCCACA GAGGACGACT TTGGATAGCA 
GCCACAGCTA AAAAACCCTC CCCTCAAGAA GTCTCAGAAC TCCAGGCTAC ATATCGTCTT 
CTTCGTGGGA AAGATGTGGA ATTTCCTAAT GACTATCCGT CAGGTTGTCT TCTGGGCTGT 
GTGGACCTAA TTGACTGCTT GTCCCAGAAG CAATTTAAGG AGCAGTTTCC AGACATCAGT 
CAAGAGTCTG ATTCTCCATT TGTTTTCATC TGCAAAAATC CTCAGGAAAT GGTTGTGAAG 
TTTCCTATTA AAGGAAATCC AAAAATCTGG AAATTGGATT CCAAGATCCA TCAAGGAGCA 
AAGAAGGGGT TAATGAAGCA GAATAAAGCT GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIP4 ( NM_001321924.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308853.1 Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu48670
Clone ID Related Accession (Same CDS sequence)	NM_001321924.1 , NM_001321924.2
Accession Version	NM_001321924.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	activating signal cointegrator 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA712387.1, AK314319.1 and BC012448.1. On May 31, 2019 this sequence version replaced NM_001321924.1. Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal exon, which results in translation initiation at an in-frame downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.54553.1, SRR1660805.16601.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGAG TGGAGAATTC TGGAAAGGTG GACATCTCTA CCAAGGACCT TCTTCCTCAT 
CAAGAATTGC GAATTAAGTC TGGTCTGGAG AAGGCTATCA AGCATAAAGA CAAACTGTTA 
GAGTTTGACA GAACTAGTAT TCGAAGGACC CAAGTCATTG ATGATGAGTC AGATTACTTT 
GCCAGTGATT CTAACCAATG GTTGTCCAAA CTTGAGCGGG AAACCTTGCA GAAGCGAGAG 
GAGGAGCTGA GAGAACTTCG ACACGCCTCT CGACTTTCTA AGAAGGTCAC CATTGACTTT 
GCAGGAAGGA AGATCCTGGA AGAAGAAAAT TCACTAGCAG AGTATCATAG CAGACTAGAT 
GAGACAATAC AGGCCATTGC CAATGGAACC TTGAACCAGC CACTGACCAA ATTGGATAGA 
TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA AATCCCAACA TGTACCAGTC CCCTCCCCAG 
TGGGTTGACC ACACAGGTGC AGCCTCACAG AAGAAGGCTT TCCGTTCTTC AGGATTTGGA 
CTAGAGTTCA ACTCATTTCA GCACCAGTTG CGAATCCAGG ATCAAGAATT TCAGGAAGGC 
TTTGATGGTG GCTGGTGCCT CTCTGTACAT CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG 
ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC ACCCCCCACA GAGGACGACT TTGGATAGCA 
GCCACAGCTA AAAAACCCTC CCCTCAAGAA GTCTCAGAAC TCCAGGCTAC ATATCGTCTT 
CTTCGTGGGA AAGATGTGGA ATTTCCTAAT GACTATCCGT CAGGTTGTCT TCTGGGCTGT 
GTGGACCTAA TTGACTGCTT GTCCCAGAAG CAATTTAAGG AGCAGTTTCC AGACATCAGT 
CAAGAGTCTG ATTCTCCATT TGTTTTCATC TGCAAAAATC CTCAGGAAAT GGTTGTGAAG 
TTTCCTATTA AAGGAAATCC AAAAATCTGG AAATTGGATT CCAAGATCCA TCAAGGAGCA 
AAGAAGGGGT TAATGAAGCA GAATAAAGCT GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308853.1
CDS	803..1858
Translation	MSGVENSGKVDISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV

Target ORF information:

RefSeq Version	NM_001321924.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321924.2

ORF Insert Sequence:

ATGTCAGGAG TGGAGAATTC TGGAAAGGTG GACATCTCTA CCAAGGACCT TCTTCCTCAT 
CAAGAATTGC GAATTAAGTC TGGTCTGGAG AAGGCTATCA AGCATAAAGA CAAACTGTTA 
GAGTTTGACA GAACTAGTAT TCGAAGGACC CAAGTCATTG ATGATGAGTC AGATTACTTT 
GCCAGTGATT CTAACCAATG GTTGTCCAAA CTTGAGCGGG AAACCTTGCA GAAGCGAGAG 
GAGGAGCTGA GAGAACTTCG ACACGCCTCT CGACTTTCTA AGAAGGTCAC CATTGACTTT 
GCAGGAAGGA AGATCCTGGA AGAAGAAAAT TCACTAGCAG AGTATCATAG CAGACTAGAT 
GAGACAATAC AGGCCATTGC CAATGGAACC TTGAACCAGC CACTGACCAA ATTGGATAGA 
TCTTCTGAAG AGCCTTTGGG AGTTCTGGTA AATCCCAACA TGTACCAGTC CCCTCCCCAG 
TGGGTTGACC ACACAGGTGC AGCCTCACAG AAGAAGGCTT TCCGTTCTTC AGGATTTGGA 
CTAGAGTTCA ACTCATTTCA GCACCAGTTG CGAATCCAGG ATCAAGAATT TCAGGAAGGC 
TTTGATGGTG GCTGGTGCCT CTCTGTACAT CAGCCCTGGG CTTCTCTGCT TGTCAGAGGG 
ATTAAAAGGG TGGAGGGCAG ATCCTGGTAC ACCCCCCACA GAGGACGACT TTGGATAGCA 
GCCACAGCTA AAAAACCCTC CCCTCAAGAA GTCTCAGAAC TCCAGGCTAC ATATCGTCTT 
CTTCGTGGGA AAGATGTGGA ATTTCCTAAT GACTATCCGT CAGGTTGTCT TCTGGGCTGT 
GTGGACCTAA TTGACTGCTT GTCCCAGAAG CAATTTAAGG AGCAGTTTCC AGACATCAGT 
CAAGAGTCTG ATTCTCCATT TGTTTTCATC TGCAAAAATC CTCAGGAAAT GGTTGTGAAG 
TTTCCTATTA AAGGAAATCC AAAAATCTGG AAATTGGATT CCAAGATCCA TCAAGGAGCA 
AAGAAGGGGT TAATGAAGCA GAATAAAGCT GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.
The Journal of investigative dermatology138(1)159-170(2018 Jan)
Hao J,Xu H,Luo M,Yu W,Chen M,Liao Y,Zhang C,Zhao X,Jiang W,Hou S,Feng X,Zou K,Chen Y,Huang W,Guo W,Kang L,Deng W

The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease.
Human molecular genetics25(8)1559-73(2016 Apr)
Davignon L,Chauveau C,Julien C,Dill C,Duband-Goulet I,Cabet E,Buendia B,Lilienbaum A,Rendu J,Minot MC,Guichet A,Allamand V,Vadrot N,Faur? J,Odent S,Lazaro L,Leroy JP,Marcorelles P,Dubourg O,Ferreiro A

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures.
American journal of human genetics98(3)473-489(2016 Mar)
Knierim E,Hirata H,Wolf NI,Morales-Gonzalez S,Schottmann G,Tanaka Y,Rudnik-Sch?neborn S,Orgeur M,Zerres K,Vogt S,van Riesen A,Gill E,Seifert F,Zwirner A,Kirschner J,Goebel HH,H?bner C,Stricker S,Meierhofer D,Stenzel W,Schuelke M

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Molecular cell56(2)261-74(2014 Oct)
Yoo HM,Kang SH,Kim JY,Lee JE,Seong MW,Lee SW,Ka SH,Sou YS,Komatsu M,Tanaka K,Lee ST,Noh DY,Baek SH,Jeon YJ,Chung CH

Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.
Translational psychiatry4e358(2014 Feb)
Ruiz A,Heilmann S,Becker T,Hern?ndez I,Wagner H,Thelen M,Maule?n A,Rosende-Roca M,Bellenguez C,Bis JC,Harold D,Gerrish A,Sims R,Sotolongo-Grau O,Espinosa A,Alegret M,Arrieta JL,Lacour A,Leber M,Becker J,Lafuente A,Ruiz S,Vargas L,Rodr?guez O,Ortega G,Dominguez MA,,Mayeux R,Haines JL,Pericak-Vance MA,Farrer LA,Schellenberg GD,Chouraki V,Launer LJ,van Duijn C,Seshadri S,Ant?nez C,Breteler MM,Serrano-R?os M,Jessen F,T?rraga L,N?then MM,Maier W,Boada M,Ram?rez A

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TRIP4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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