GCNT3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GCNT3
Entrez Gene ID	9245
Full Name	glucosaminyl (N-acetyl) transferase 3, mucin type
Synonyms	C2/4GnT,C24GNT,C2GNT2,C2GNTM,GNTM
General protein information	Preferred Names glucosaminyl (N-acetyl) transferase 3, mucin type Names beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 C2GnT-mucin type beta1,6-N-acetylglucosaminyltransferase-M beta1,6GlcNAc-transferase core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase hC2GnT-M mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.2
Summary	This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009].
Disorder MIM:	606836

mRNA and Protein(s)

mRNA	Protein	Name
NM_004751.3	NP_004742.1	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
NM_004751.2	NP_004742.1	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	GCNT3	NP_004742.1
Bos taurus (cattle)	GCNT3	NP_991378.1
Danio rerio (zebrafish)	gcnt3	XP_002666963.1
Rattus norvegicus (Norway rat)	Gcnt3	NP_775434.1
Caenorhabditis elegans (roundworm)	gly-19	NP_492015.1
Caenorhabditis elegans (roundworm)	gly-18	NP_492014.4
Xenopus tropicalis (tropical clawed frog)	LOC100486342	XP_002937937.1
Canis lupus familiaris (dog)	GCNT3	XP_005638526.1
Mus musculus (house mouse)	Gcnt3	NP_082363.2
Gallus gallus (chicken)	GCNT3	XP_425064.2
Caenorhabditis elegans (roundworm)	gly-1	NP_496345.1
Pan troglodytes (chimpanzee)	GCNT3	XP_510451.2
	GCNT3	XP_001099658.1
Caenorhabditis elegans (roundworm)	gly-16	NP_493135.2
Caenorhabditis elegans (roundworm)	gly-17	NP_493134.2
Caenorhabditis elegans (roundworm)	gly-15	NP_493164.2

Gene Ontology
Bibliography

Related articles in PubMed

?-1,3-galactosyl-O-glycosyl-glycoprotein ?-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.
Sumardika IW, Youyi C, Kondo E, Inoue Y, Ruma IMW, Murata H, Kinoshita R, Yamamoto KI, Tomida S, Shien K, Satoh H, Yamauchi A, Futami J, Putranto EW, Hibino T, Toyooka S, Nishibori M, Sakaguchi M
Oncology research(2017 Sep)

Molecular Pathways: Mucins and Drug Delivery in Cancer.
Rao CV, Janakiram NB, Mohammed A
Clinical cancer research : an official journal of the American Association for Cancer Research23(6)1373-1378(2017 Mar)

Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells.
Ye J, Song L, Liu Y, Pan Q, Zhong X, Li S, Shang Y, Tian Y, He Y, Chen L, Chen W, Peng Z, Wang R
Digestive diseases and sciences60(7)1977-90(2015 Jul)

Keratin 1 plays a critical role in golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail.
Petrosyan A, Ali MF, Cheng PW
The Journal of biological chemistry290(10)6256-69(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study provides the concepts toward the design of carbohydrate-dependent inhibition of EPEC and EHEC O157:H7 adhesion to human intestinal epithelial cells.
Title: Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells.

In HeLa cells transiently expressing C2GnT-M-GFP, knockdown of KRT1 does not affect Golgi morphology but leaves C2GnT-M outside of the Golgi, resulting in the formation of sialyl-T antigen.
Title: Keratin 1 plays a critical role in golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail.

low GCNT3 expression is a promising prognostic biomarker for colon cancer that could be used to identify early-stage colon cancer patients at high risk of relapse.
Title: Clinical relevance of the differential expression of the glycosyltransferase gene GCNT3 in colon cancer.

Golgi fragmentation is accompanied by the increased association of NMIIA with C2GnT-M and its degradation by proteasomes.
Title: A non-enzymatic function of Golgi glycosyltransferases: mediation of Golgi fragmentation by interaction with non-muscle myosin IIA.

Data show that the Golgi docking of vesicular complexes (VCs) use different golgins for docking: C2GnT-M-carrying VC (C2GnT-M-VC) utilizes Giantin, whereas C1GalT1-VC employs GM130-GRASP65 complex.
Title: Glycosyltransferase-specific Golgi-targeting mechanisms.

The following GCNT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GCNT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08589	NM_004751.3 Latest version!	Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu08589	NM_004751.2	Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GCNT3 ( NM_004751.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004742.1 Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.

Price & Availability↑

CloneID	OHu08589
Clone ID Related Accession (Same CDS sequence)	NM_004751.3 , NM_004751.2
Accession Version	NM_004751.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP243086.1, BC017032.1 and AC092755.4. On Nov 23, 2018 this sequence version replaced NM_004751.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP243086.1, BC017032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000396065.3/ ENSP00000379377.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTTCAAT GGAAGAGACT CTGCCAGCTG CATTACTTGT GGGCTCTGGG CTGCTATATG 
CTGCTGGCCA CTGTGGCTCT GAAACTTTCT TTCAGGTTGA AGTGTGACTC TGACCACTTG 
GGTCTGGAGT CCAGGGAATC TCAAAGCCAG TACTGTAGGA ATATCTTGTA TAATTTCCTG 
AAACTTCCAG CAAAGAGGTC TATCAACTGT TCAGGGGTCA CCCGAGGGGA CCAAGAGGCA 
GTGCTTCAGG CTATTCTGAA TAACCTGGAG GTCAAGAAGA AGCGAGAGCC TTTCACAGAC 
ACCCACTACC TCTCCCTCAC CAGAGACTGT GAGCACTTCA AGGCTGAAAG GAAGTTCATA 
CAGTTCCCAC TGAGCAAAGA AGAGGTGGAG TTCCCTATTG CATACTCTAT GGTGATTCAT 
GAGAAGATTG AAAACTTTGA AAGGCTACTG CGAGCTGTGT ATGCCCCTCA GAACATATAC 
TGTGTCCATG TGGATGAGAA GTCCCCAGAA ACTTTCAAAG AGGCGGTCAA AGCAATTATT 
TCTTGCTTCC CAAATGTCTT CATAGCCAGT AAGCTGGTTC GGGTGGTTTA TGCCTCCTGG 
TCCAGGGTGC AAGCTGACCT CAACTGCATG GAAGACTTGC TCCAGAGCTC AGTGCCGTGG 
AAATACTTCC TGAATACATG TGGGACGGAC TTTCCTATAA AGAGCAATGC AGAGATGGTC 
CAGGCTCTCA AGATGTTGAA TGGGAGGAAT AGCATGGAGT CAGAGGTACC TCCTAAGCAC 
AAAGAAACCC GCTGGAAATA TCACTTTGAG GTAGTGAGAG ACACATTACA CCTAACCAAC 
AAGAAGAAGG ATCCTCCCCC TTATAATTTA ACTATGTTTA CAGGGAATGC GTACATTGTG 
GCTTCCCGAG ATTTCGTCCA ACATGTTTTG AAGAACCCTA AATCCCAACA ACTGATTGAA 
TGGGTAAAAG ACACTTATAG CCCAGATGAA CACCTCTGGG CCACCCTTCA GCGTGCACGG 
TGGATGCCTG GCTCTGTTCC CAACCACCCC AAGTACGACA TCTCAGACAT GACTTCTATT 
GCCAGGCTGG TCAAGTGGCA GGGTCATGAG GGAGACATCG ATAAGGGTGC TCCTTATGCT 
CCCTGCTCTG GAATCCACCA GCGGGCTATC TGCGTTTATG GGGCTGGGGA CTTGAATTGG 
ATGCTTCAAA ACCATCACCT GTTGGCCAAC AAGTTTGACC CAAAGGTAGA TGATAATGCT 
CTTCAGTGCT TAGAAGAATA CCTACGTTAT AAGGCCATCT ATGGGACTGA ACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004742.1
CDS	450..1766
Translation	MVQWKRLCQLHYLWALGCYMLLATVALKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFIASKLVRVVYASWSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSMESEVPPKHKETRWKYHFEVVRDTLHLTNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLKNPKSQQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEGDIDKGAPYAPCSGIHQRAICVYGAGDLNWMLQNHHLLANKFDPKVDDNALQCLEEYLRYKAIYGTEL

Target ORF information:

RefSeq Version	NM_004751.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004751.3

ORF Insert Sequence:

ATGGTTCAAT GGAAGAGACT CTGCCAGCTG CATTACTTGT GGGCTCTGGG CTGCTATATG 
CTGCTGGCCA CTGTGGCTCT GAAACTTTCT TTCAGGTTGA AGTGTGACTC TGACCACTTG 
GGTCTGGAGT CCAGGGAATC TCAAAGCCAG TACTGTAGGA ATATCTTGTA TAATTTCCTG 
AAACTTCCAG CAAAGAGGTC TATCAACTGT TCAGGGGTCA CCCGAGGGGA CCAAGAGGCA 
GTGCTTCAGG CTATTCTGAA TAACCTGGAG GTCAAGAAGA AGCGAGAGCC TTTCACAGAC 
ACCCACTACC TCTCCCTCAC CAGAGACTGT GAGCACTTCA AGGCTGAAAG GAAGTTCATA 
CAGTTCCCAC TGAGCAAAGA AGAGGTGGAG TTCCCTATTG CATACTCTAT GGTGATTCAT 
GAGAAGATTG AAAACTTTGA AAGGCTACTG CGAGCTGTGT ATGCCCCTCA GAACATATAC 
TGTGTCCATG TGGATGAGAA GTCCCCAGAA ACTTTCAAAG AGGCGGTCAA AGCAATTATT 
TCTTGCTTCC CAAATGTCTT CATAGCCAGT AAGCTGGTTC GGGTGGTTTA TGCCTCCTGG 
TCCAGGGTGC AAGCTGACCT CAACTGCATG GAAGACTTGC TCCAGAGCTC AGTGCCGTGG 
AAATACTTCC TGAATACATG TGGGACGGAC TTTCCTATAA AGAGCAATGC AGAGATGGTC 
CAGGCTCTCA AGATGTTGAA TGGGAGGAAT AGCATGGAGT CAGAGGTACC TCCTAAGCAC 
AAAGAAACCC GCTGGAAATA TCACTTTGAG GTAGTGAGAG ACACATTACA CCTAACCAAC 
AAGAAGAAGG ATCCTCCCCC TTATAATTTA ACTATGTTTA CAGGGAATGC GTACATTGTG 
GCTTCCCGAG ATTTCGTCCA ACATGTTTTG AAGAACCCTA AATCCCAACA ACTGATTGAA 
TGGGTAAAAG ACACTTATAG CCCAGATGAA CACCTCTGGG CCACCCTTCA GCGTGCACGG 
TGGATGCCTG GCTCTGTTCC CAACCACCCC AAGTACGACA TCTCAGACAT GACTTCTATT 
GCCAGGCTGG TCAAGTGGCA GGGTCATGAG GGAGACATCG ATAAGGGTGC TCCTTATGCT 
CCCTGCTCTG GAATCCACCA GCGGGCTATC TGCGTTTATG GGGCTGGGGA CTTGAATTGG 
ATGCTTCAAA ACCATCACCT GTTGGCCAAC AAGTTTGACC CAAAGGTAGA TGATAATGCT 
CTTCAGTGCT TAGAAGAATA CCTACGTTAT AAGGCCATCT ATGGGACTGA ACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GCNT3 ( NM_004751.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004742.1 Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.

Price & Availability↑

CloneID	OHu08589
Clone ID Related Accession (Same CDS sequence)	NM_004751.3 , NM_004751.2
Accession Version	NM_004751.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP243086.1, BC017032.1 and AC092755.4. On Apr 7, 2009 this sequence version replaced NM_004751.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017032.1, BU501371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTTCAAT GGAAGAGACT CTGCCAGCTG CATTACTTGT GGGCTCTGGG CTGCTATATG 
CTGCTGGCCA CTGTGGCTCT GAAACTTTCT TTCAGGTTGA AGTGTGACTC TGACCACTTG 
GGTCTGGAGT CCAGGGAATC TCAAAGCCAG TACTGTAGGA ATATCTTGTA TAATTTCCTG 
AAACTTCCAG CAAAGAGGTC TATCAACTGT TCAGGGGTCA CCCGAGGGGA CCAAGAGGCA 
GTGCTTCAGG CTATTCTGAA TAACCTGGAG GTCAAGAAGA AGCGAGAGCC TTTCACAGAC 
ACCCACTACC TCTCCCTCAC CAGAGACTGT GAGCACTTCA AGGCTGAAAG GAAGTTCATA 
CAGTTCCCAC TGAGCAAAGA AGAGGTGGAG TTCCCTATTG CATACTCTAT GGTGATTCAT 
GAGAAGATTG AAAACTTTGA AAGGCTACTG CGAGCTGTGT ATGCCCCTCA GAACATATAC 
TGTGTCCATG TGGATGAGAA GTCCCCAGAA ACTTTCAAAG AGGCGGTCAA AGCAATTATT 
TCTTGCTTCC CAAATGTCTT CATAGCCAGT AAGCTGGTTC GGGTGGTTTA TGCCTCCTGG 
TCCAGGGTGC AAGCTGACCT CAACTGCATG GAAGACTTGC TCCAGAGCTC AGTGCCGTGG 
AAATACTTCC TGAATACATG TGGGACGGAC TTTCCTATAA AGAGCAATGC AGAGATGGTC 
CAGGCTCTCA AGATGTTGAA TGGGAGGAAT AGCATGGAGT CAGAGGTACC TCCTAAGCAC 
AAAGAAACCC GCTGGAAATA TCACTTTGAG GTAGTGAGAG ACACATTACA CCTAACCAAC 
AAGAAGAAGG ATCCTCCCCC TTATAATTTA ACTATGTTTA CAGGGAATGC GTACATTGTG 
GCTTCCCGAG ATTTCGTCCA ACATGTTTTG AAGAACCCTA AATCCCAACA ACTGATTGAA 
TGGGTAAAAG ACACTTATAG CCCAGATGAA CACCTCTGGG CCACCCTTCA GCGTGCACGG 
TGGATGCCTG GCTCTGTTCC CAACCACCCC AAGTACGACA TCTCAGACAT GACTTCTATT 
GCCAGGCTGG TCAAGTGGCA GGGTCATGAG GGAGACATCG ATAAGGGTGC TCCTTATGCT 
CCCTGCTCTG GAATCCACCA GCGGGCTATC TGCGTTTATG GGGCTGGGGA CTTGAATTGG 
ATGCTTCAAA ACCATCACCT GTTGGCCAAC AAGTTTGACC CAAAGGTAGA TGATAATGCT 
CTTCAGTGCT TAGAAGAATA CCTACGTTAT AAGGCCATCT ATGGGACTGA ACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004742.1
CDS	450..1766
Translation	MVQWKRLCQLHYLWALGCYMLLATVALKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFIASKLVRVVYASWSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSMESEVPPKHKETRWKYHFEVVRDTLHLTNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLKNPKSQQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEGDIDKGAPYAPCSGIHQRAICVYGAGDLNWMLQNHHLLANKFDPKVDDNALQCLEEYLRYKAIYGTEL

Target ORF information:

RefSeq Version	NM_004751.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glucosaminyl (N-acetyl) transferase 3, mucin type (GCNT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004751.2

ORF Insert Sequence:

ATGGTTCAAT GGAAGAGACT CTGCCAGCTG CATTACTTGT GGGCTCTGGG CTGCTATATG 
CTGCTGGCCA CTGTGGCTCT GAAACTTTCT TTCAGGTTGA AGTGTGACTC TGACCACTTG 
GGTCTGGAGT CCAGGGAATC TCAAAGCCAG TACTGTAGGA ATATCTTGTA TAATTTCCTG 
AAACTTCCAG CAAAGAGGTC TATCAACTGT TCAGGGGTCA CCCGAGGGGA CCAAGAGGCA 
GTGCTTCAGG CTATTCTGAA TAACCTGGAG GTCAAGAAGA AGCGAGAGCC TTTCACAGAC 
ACCCACTACC TCTCCCTCAC CAGAGACTGT GAGCACTTCA AGGCTGAAAG GAAGTTCATA 
CAGTTCCCAC TGAGCAAAGA AGAGGTGGAG TTCCCTATTG CATACTCTAT GGTGATTCAT 
GAGAAGATTG AAAACTTTGA AAGGCTACTG CGAGCTGTGT ATGCCCCTCA GAACATATAC 
TGTGTCCATG TGGATGAGAA GTCCCCAGAA ACTTTCAAAG AGGCGGTCAA AGCAATTATT 
TCTTGCTTCC CAAATGTCTT CATAGCCAGT AAGCTGGTTC GGGTGGTTTA TGCCTCCTGG 
TCCAGGGTGC AAGCTGACCT CAACTGCATG GAAGACTTGC TCCAGAGCTC AGTGCCGTGG 
AAATACTTCC TGAATACATG TGGGACGGAC TTTCCTATAA AGAGCAATGC AGAGATGGTC 
CAGGCTCTCA AGATGTTGAA TGGGAGGAAT AGCATGGAGT CAGAGGTACC TCCTAAGCAC 
AAAGAAACCC GCTGGAAATA TCACTTTGAG GTAGTGAGAG ACACATTACA CCTAACCAAC 
AAGAAGAAGG ATCCTCCCCC TTATAATTTA ACTATGTTTA CAGGGAATGC GTACATTGTG 
GCTTCCCGAG ATTTCGTCCA ACATGTTTTG AAGAACCCTA AATCCCAACA ACTGATTGAA 
TGGGTAAAAG ACACTTATAG CCCAGATGAA CACCTCTGGG CCACCCTTCA GCGTGCACGG 
TGGATGCCTG GCTCTGTTCC CAACCACCCC AAGTACGACA TCTCAGACAT GACTTCTATT 
GCCAGGCTGG TCAAGTGGCA GGGTCATGAG GGAGACATCG ATAAGGGTGC TCCTTATGCT 
CCCTGCTCTG GAATCCACCA GCGGGCTATC TGCGTTTATG GGGCTGGGGA CTTGAATTGG 
ATGCTTCAAA ACCATCACCT GTTGGCCAAC AAGTTTGACC CAAAGGTAGA TGATAATGCT 
CTTCAGTGCT TAGAAGAATA CCTACGTTAT AAGGCCATCT ATGGGACTGA ACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

?-1,3-galactosyl-O-glycosyl-glycoprotein ?-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.
Oncology research(2017 Sep)
Sumardika IW,Youyi C,Kondo E,Inoue Y,Ruma IMW,Murata H,Kinoshita R,Yamamoto KI,Tomida S,Shien K,Satoh H,Yamauchi A,Futami J,Putranto EW,Hibino T,Toyooka S,Nishibori M,Sakaguchi M

Molecular Pathways: Mucins and Drug Delivery in Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research23(6)1373-1378(2017 Mar)
Rao CV,Janakiram NB,Mohammed A

Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells.
Digestive diseases and sciences60(7)1977-90(2015 Jul)
Ye J,Song L,Liu Y,Pan Q,Zhong X,Li S,Shang Y,Tian Y,He Y,Chen L,Chen W,Peng Z,Wang R

Keratin 1 plays a critical role in golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail.
The Journal of biological chemistry290(10)6256-69(2015 Mar)
Petrosyan A,Ali MF,Cheng PW

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GCNT3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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