CCNQ cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCNQ
Entrez Gene ID	92002
Full Name	cyclin Q
Synonyms	FAM58A,STAR
General protein information	Preferred Names cyclin Q Names cyclin-Q cyclin-related protein FAM58A CDK10-activating cyclin cyclin M family with sequence similarity 58 member A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
Disorder MIM:	300708
Disorder Html:	STAR syndrome, 300707 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_152274.5	NP_689487.2	cyclin-Q isoform 1
XM_005277920.4	XP_005277977.1	cyclin-Q isoform X1
XM_011531215.2	XP_011529517.1	cyclin-Q isoform X3
XM_011531214.2	XP_011529516.1	cyclin-Q isoform X3
NM_152274.4	NP_689487.2	cyclin-Q isoform 1
NM_001130997.3	NP_001124469.1	cyclin-Q isoform 2
NM_001130997.2	NP_001124469.1	cyclin-Q isoform 2
XM_005277921.4	XP_005277978.1	cyclin-Q isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	FAM58A	NP_689487.2
Mus musculus (house mouse)	Fam58b	NP_932106.1
Pan troglodytes (chimpanzee)	FAM58A	XP_001137614.2
	FAM58A	XP_001083983.1
Canis lupus familiaris (dog)	FAM58A	XP_549359.3
Bos taurus (cattle)	FAM58A	XP_002699785.1
Rattus norvegicus (Norway rat)	Fam58b	NP_001020583.1
Drosophila melanogaster (fruit fly)	koko	NP_732339.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012763	XP_307016.3
Xenopus tropicalis (tropical clawed frog)	fam58a	NP_001016916.1
Danio rerio (zebrafish)	fam58a	NP_001018459.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005056	XP_313929.4

Gene Ontology
Bibliography

Related articles in PubMed

Multigenerational pedigree with STAR syndrome: A novel FAM58A variant and expansion of the phenotype.
Boczek NJ, Kruisselbrink T, Cousin MA, Blackburn PR, Klee EW, Gavrilova RH, Lanpher BC
American journal of medical genetics. Part A173(5)1328-1333(2017 May)

Ocular manifestations of X-linked dominant FAM58A mutation in toe syndactyly, telecanthus, anogenital, and renal malformations ('STAR') syndrome.
Orge FH, Dar SA, Blackburn CN, Grimes-Hodges SJ, Mitchell AL
Ophthalmic genetics37(3)323-7(2016 09)

STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.
Guen VJ, Gamble C, Perez DE, Bourassa S, Zappel H, G?rtner J, Lees JA, Colas P
Cell cycle (Georgetown, Tex.)15(5)678-88(2016)

CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.
Guen VJ, Gamble C, Flajolet M, Unger S, Thollet A, Ferandin Y, Superti-Furga A, Cohen PA, Meijer L, Colas P
Proceedings of the National Academy of Sciences of the United States of America110(48)19525-30(2013 Nov)

A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
Li H, Gan W, Lu L, Dong X, Han X, Hu C, Yang Z, Sun L, Bao W, Li P, He M, Sun L, Wang Y, Zhu J, Ning Q, Tang Y, Zhang R, Wen J, Wang D, Zhu X, Guo K, Zuo X, Guo X, Yang H, Zhou X, , , Zhang X, Qi L, Loos RJ, Hu FB, Wu T, Liu Y, Liu L, Yang Z, Hu R, Jia W, Ji L, Li Y, Lin X
Diabetes62(1)291-8(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this is the first occurrence of a nonsense variant in FAM58A described in individuals with STAR syndrome and the phenotype in this pedigree suggests that tethered cord and hearing loss are features of STAR syndrome.
Title: Multigenerational pedigree with STAR syndrome: A novel FAM58A variant and expansion of the phenotype.

These ophthalmic findings are the first reported to our knowledge in association with STAR syndrome. The literature frequently demonstrates that patients with developmental anomalies often have ocular manifestations, warranting a full ophthalmic examination when the diagnosis of STAR syndrome has been made or is being considered.
Title: Ocular manifestations of X-linked dominant FAM58A mutation in toe syndactyly, telecanthus, anogenital, and renal malformations ('STAR') syndrome.

Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations.
Title: Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations.

The following CCNQ gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCNQ cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21176	NM_152274.5 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu74416	XM_011531214.2 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu74416	XM_011531215.2 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu14312	NM_001130997.3 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
OHu54465	XM_005277920.4 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu54466	XM_005277921.4 Latest version!	Homo sapiens cyclin Q (CCNQ), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu21176	NM_152274.4	Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14312	NM_001130997.2	Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCNQ ( NM_152274.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_689487.2 Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21176
Clone ID Related Accession (Same CDS sequence)	NM_152274.5 , NM_152274.4
Accession Version	NM_152274.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	cyclin-Q isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG766429.1 and BC001909.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_152274.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC032121.2, ERR279840.6270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267773 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000576892.8/ ENSP00000461135.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG 
TTTAATGACG ACCTTACCAA GCCAATCATT GATAATATTG TGTCTGATCT CATTCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689487.2
CDS	67..813
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP

Target ORF information:

RefSeq Version	NM_152274.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152274.5

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG 
TTTAATGACG ACCTTACCAA GCCAATCATT GATAATATTG TGTCTGATCT CATTCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( NM_152274.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_689487.2 Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21176
Clone ID Related Accession (Same CDS sequence)	NM_152274.5 , NM_152274.4
Accession Version	NM_152274.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	cyclin-Q isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG766429.1 and BC001909.1. This sequence is a reference standard in the RefSeqGene project. On Jun 19, 2013 this sequence version replaced NM_152274.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC001909.1, ERR279840.6270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267773 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG 
TTTAATGACG ACCTTACCAA GCCAATCATT GATAATATTG TGTCTGATCT CATTCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689487.2
CDS	105..851
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP

Target ORF information:

RefSeq Version	NM_152274.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152274.4

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG 
TTTAATGACG ACCTTACCAA GCCAATCATT GATAATATTG TGTCTGATCT CATTCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( XM_011531215.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529517.1 Homo sapiens cyclin Q (CCNQ), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu74416
Clone ID Related Accession (Same CDS sequence)	XM_011531215.2 , XM_011531214.2
Accession Version	XM_011531215.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-Q isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531215.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGTCCA TTCCCATTGC CACTGCTTGC ACCATTTACC ATAAGTTCTT TTGCGAGACC 
AACCTGGACG CCTATGACCC TTACCTGATT GCCATGTCTT CAATTTACTT GGCCGGCAAA 
GTGGAAGAGC AGCACCTGCG GACTCGTGAC ATCATCAATG TGTCCAACAG GTACTTTAAC 
CCAAGCGGTG AGCCCCTGGA ATTGGACTCC CGCTTCTGGG AACTCCGGGA CAGCATCGTG 
CAGTGTGAGC TTCTCATGCT GAGAGTTCTG CGCTTCCAGG TCTCCTTCCA GCATCCACAC 
AAGTACCTGC TCCACTACCT GGTTTCCCTC CAGAACTGGC TGAACCGCCA CAGCTGGCAG 
CGGACCCCTG TTGCCGTCAC CGCCTGGGCC CTGCTGCGGG ACAGCTACCA TGGGGCGCTG 
TGCCTCCGCT TCCAGGCCCA GCACATCGCC GTGGCGGTGC TCTACCTGGC CCTGCAGGTC 
TACGGAGTTG AGGTGCCCGC CGAGGTCGAG GCTGAGAAGC CGTGGTGGCA GGTGTTTAAT 
GACGACCTTA CCAAGCCAAT CATTGATAAT ATTGTGTCTG ATCTCATTCA GATTTATACC 
ATGGACACAG AGATCCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529517.1
CDS	621..1241
Translation	MRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP

Target ORF information:

RefSeq Version	XM_011531215.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531215.2

ORF Insert Sequence:

ATGCGGTCCA TTCCCATTGC CACTGCTTGC ACCATTTACC ATAAGTTCTT TTGCGAGACC 
AACCTGGACG CCTATGACCC TTACCTGATT GCCATGTCTT CAATTTACTT GGCCGGCAAA 
GTGGAAGAGC AGCACCTGCG GACTCGTGAC ATCATCAATG TGTCCAACAG GTACTTTAAC 
CCAAGCGGTG AGCCCCTGGA ATTGGACTCC CGCTTCTGGG AACTCCGGGA CAGCATCGTG 
CAGTGTGAGC TTCTCATGCT GAGAGTTCTG CGCTTCCAGG TCTCCTTCCA GCATCCACAC 
AAGTACCTGC TCCACTACCT GGTTTCCCTC CAGAACTGGC TGAACCGCCA CAGCTGGCAG 
CGGACCCCTG TTGCCGTCAC CGCCTGGGCC CTGCTGCGGG ACAGCTACCA TGGGGCGCTG 
TGCCTCCGCT TCCAGGCCCA GCACATCGCC GTGGCGGTGC TCTACCTGGC CCTGCAGGTC 
TACGGAGTTG AGGTGCCCGC CGAGGTCGAG GCTGAGAAGC CGTGGTGGCA GGTGTTTAAT 
GACGACCTTA CCAAGCCAAT CATTGATAAT ATTGTGTCTG ATCTCATTCA GATTTATACC 
ATGGACACAG AGATCCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( XM_011531214.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529516.1 Homo sapiens cyclin Q (CCNQ), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu74416
Clone ID Related Accession (Same CDS sequence)	XM_011531215.2 , XM_011531214.2
Accession Version	XM_011531214.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-Q isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531214.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGTCCA TTCCCATTGC CACTGCTTGC ACCATTTACC ATAAGTTCTT TTGCGAGACC 
AACCTGGACG CCTATGACCC TTACCTGATT GCCATGTCTT CAATTTACTT GGCCGGCAAA 
GTGGAAGAGC AGCACCTGCG GACTCGTGAC ATCATCAATG TGTCCAACAG GTACTTTAAC 
CCAAGCGGTG AGCCCCTGGA ATTGGACTCC CGCTTCTGGG AACTCCGGGA CAGCATCGTG 
CAGTGTGAGC TTCTCATGCT GAGAGTTCTG CGCTTCCAGG TCTCCTTCCA GCATCCACAC 
AAGTACCTGC TCCACTACCT GGTTTCCCTC CAGAACTGGC TGAACCGCCA CAGCTGGCAG 
CGGACCCCTG TTGCCGTCAC CGCCTGGGCC CTGCTGCGGG ACAGCTACCA TGGGGCGCTG 
TGCCTCCGCT TCCAGGCCCA GCACATCGCC GTGGCGGTGC TCTACCTGGC CCTGCAGGTC 
TACGGAGTTG AGGTGCCCGC CGAGGTCGAG GCTGAGAAGC CGTGGTGGCA GGTGTTTAAT 
GACGACCTTA CCAAGCCAAT CATTGATAAT ATTGTGTCTG ATCTCATTCA GATTTATACC 
ATGGACACAG AGATCCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529516.1
CDS	755..1375
Translation	MRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP

Target ORF information:

RefSeq Version	XM_011531214.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531214.2

ORF Insert Sequence:

ATGCGGTCCA TTCCCATTGC CACTGCTTGC ACCATTTACC ATAAGTTCTT TTGCGAGACC 
AACCTGGACG CCTATGACCC TTACCTGATT GCCATGTCTT CAATTTACTT GGCCGGCAAA 
GTGGAAGAGC AGCACCTGCG GACTCGTGAC ATCATCAATG TGTCCAACAG GTACTTTAAC 
CCAAGCGGTG AGCCCCTGGA ATTGGACTCC CGCTTCTGGG AACTCCGGGA CAGCATCGTG 
CAGTGTGAGC TTCTCATGCT GAGAGTTCTG CGCTTCCAGG TCTCCTTCCA GCATCCACAC 
AAGTACCTGC TCCACTACCT GGTTTCCCTC CAGAACTGGC TGAACCGCCA CAGCTGGCAG 
CGGACCCCTG TTGCCGTCAC CGCCTGGGCC CTGCTGCGGG ACAGCTACCA TGGGGCGCTG 
TGCCTCCGCT TCCAGGCCCA GCACATCGCC GTGGCGGTGC TCTACCTGGC CCTGCAGGTC 
TACGGAGTTG AGGTGCCCGC CGAGGTCGAG GCTGAGAAGC CGTGGTGGCA GGTGTTTAAT 
GACGACCTTA CCAAGCCAAT CATTGATAAT ATTGTGTCTG ATCTCATTCA GATTTATACC 
ATGGACACAG AGATCCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( NM_001130997.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124469.1 Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.

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CloneID	OHu14312
Clone ID Related Accession (Same CDS sequence)	NM_001130997.3 , NM_001130997.2
Accession Version	NM_001130997.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-20
Organism	Homo sapiens(human)
Product	cyclin-Q isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG766429.1 and BC001909.1. On May 31, 2019 this sequence version replaced NM_001130997.2. Transcript Variant: This variant (2) differs in the 3' coding region, compared to variant 1, resulting in an isoform (2) with a region missing from the C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.142882.1, SRR1163657.442324.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124469.1
CDS	67..753
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQIYTMDTEIP

Target ORF information:

RefSeq Version	NM_001130997.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130997.3

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( NM_001130997.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124469.1 Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14312
Clone ID Related Accession (Same CDS sequence)	NM_001130997.3 , NM_001130997.2
Accession Version	NM_001130997.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-05
Organism	Homo sapiens(human)
Product	cyclin-Q isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG766429.1 and BC001909.1. On Jun 19, 2013 this sequence version replaced NM_001130997.1. Transcript Variant: This variant (2) differs in the 3' coding region, compared to variant 1, resulting in an isoform (2) with a region missing from the C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.142882.1, SRR1163657.236011.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124469.1
CDS	105..791
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQIYTMDTEIP

Target ORF information:

RefSeq Version	NM_001130997.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130997.2

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGT ACCTGCTCCA CTACCTGGTT TCCCTCCAGA ACTGGCTGAA CCGCCACAGC 
TGGCAGCGGA CCCCTGTTGC CGTCACCGCC TGGGCCCTGC TGCGGGACAG CTACCATGGG 
GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG 
CAGGTCTACG GAGTTGAGGT GCCCGCCGAG GTCGAGGCTG AGAAGCCGTG GTGGCAGATT 
TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( XM_005277920.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005277977.1 Homo sapiens cyclin Q (CCNQ), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu54465
Clone ID Related Accession (Same CDS sequence)	XM_005277920.4
Accession Version	XM_005277920.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-Q isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005277920.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGA ACTGGCTGAA CCGCCACAGC TGGCAGCGGA CCCCTGTTGC CGTCACCGCC 
TGGGCCCTGC TGCGGGACAG CTACCATGGG GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC 
ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG CAGGTCTACG GAGTTGAGGT GCCCGCCGAG 
GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG TTTAATGACG ACCTTACCAA GCCAATCATT 
GATAATATTG TGTCTGATCT CATTCAGATT TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005277977.1
CDS	93..809
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP

Target ORF information:

RefSeq Version	XM_005277920.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005277920.4

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGA ACTGGCTGAA CCGCCACAGC TGGCAGCGGA CCCCTGTTGC CGTCACCGCC 
TGGGCCCTGC TGCGGGACAG CTACCATGGG GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC 
ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG CAGGTCTACG GAGTTGAGGT GCCCGCCGAG 
GTCGAGGCTG AGAAGCCGTG GTGGCAGGTG TTTAATGACG ACCTTACCAA GCCAATCATT 
GATAATATTG TGTCTGATCT CATTCAGATT TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNQ ( XM_005277921.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005277978.1 Homo sapiens cyclin Q (CCNQ), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu54466
Clone ID Related Accession (Same CDS sequence)	XM_005277921.4
Accession Version	XM_005277921.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-Q isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005277921.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGA ACTGGCTGAA CCGCCACAGC TGGCAGCGGA CCCCTGTTGC CGTCACCGCC 
TGGGCCCTGC TGCGGGACAG CTACCATGGG GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC 
ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG CAGGTCTACG GAGTTGAGGT GCCCGCCGAG 
GTCGAGGCTG AGAAGCCGTG GTGGCAGATT TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005277978.1
CDS	93..749
Translation	MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQIYTMDTEIP

Target ORF information:

RefSeq Version	XM_005277921.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin Q (CCNQ), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005277921.4

ORF Insert Sequence:

ATGGAAGCCC CGGAGGGCGG CGGAGGGGGG CCTGCAGCGC GGGGCCCGGA GGGGCAGCCG 
GCGCCCGAAG CCAGGGTGCA CTTCCGAGTG GCGAGGTTCA TCATGGAGGC AGGTGTCAAG 
CTAGGGATGC GGTCCATTCC CATTGCCACT GCTTGCACCA TTTACCATAA GTTCTTTTGC 
GAGACCAACC TGGACGCCTA TGACCCTTAC CTGATTGCCA TGTCTTCAAT TTACTTGGCC 
GGCAAAGTGG AAGAGCAGCA CCTGCGGACT CGTGACATCA TCAATGTGTC CAACAGGTAC 
TTTAACCCAA GCGGTGAGCC CCTGGAATTG GACTCCCGCT TCTGGGAACT CCGGGACAGC 
ATCGTGCAGT GTGAGCTTCT CATGCTGAGA GTTCTGCGCT TCCAGGTCTC CTTCCAGCAT 
CCACACAAGA ACTGGCTGAA CCGCCACAGC TGGCAGCGGA CCCCTGTTGC CGTCACCGCC 
TGGGCCCTGC TGCGGGACAG CTACCATGGG GCGCTGTGCC TCCGCTTCCA GGCCCAGCAC 
ATCGCCGTGG CGGTGCTCTA CCTGGCCCTG CAGGTCTACG GAGTTGAGGT GCCCGCCGAG 
GTCGAGGCTG AGAAGCCGTG GTGGCAGATT TATACCATGG ACACAGAGAT CCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multigenerational pedigree with STAR syndrome: A novel FAM58A variant and expansion of the phenotype.
American journal of medical genetics. Part A173(5)1328-1333(2017 May)
Boczek NJ,Kruisselbrink T,Cousin MA,Blackburn PR,Klee EW,Gavrilova RH,Lanpher BC

Ocular manifestations of X-linked dominant FAM58A mutation in toe syndactyly, telecanthus, anogenital, and renal malformations ('STAR') syndrome.
Ophthalmic genetics37(3)323-7(2016 09)
Orge FH,Dar SA,Blackburn CN,Grimes-Hodges SJ,Mitchell AL

STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.
Cell cycle (Georgetown, Tex.)15(5)678-88(2016)
Guen VJ,Gamble C,Perez DE,Bourassa S,Zappel H,G?rtner J,Lees JA,Colas P

CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.
Proceedings of the National Academy of Sciences of the United States of America110(48)19525-30(2013 Nov)
Guen VJ,Gamble C,Flajolet M,Unger S,Thollet A,Ferandin Y,Superti-Furga A,Cohen PA,Meijer L,Colas P

A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
Diabetes62(1)291-8(2013 Jan)
Li H,Gan W,Lu L,Dong X,Han X,Hu C,Yang Z,Sun L,Bao W,Li P,He M,Sun L,Wang Y,Zhu J,Ning Q,Tang Y,Zhang R,Wen J,Wang D,Zhu X,Guo K,Zuo X,Guo X,Yang H,Zhou X,,,Zhang X,Qi L,Loos RJ,Hu FB,Wu T,Liu Y,Liu L,Yang Z,Hu R,Jia W,Ji L,Li Y,Lin X

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CCNQ cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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