PAGE5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAGE5
Entrez Gene ID	90737
Full Name	PAGE family member 5
Synonyms	CT16,CT16.1,CT16.2,GAGEE1,PAGE-5
General protein information	Preferred Names PAGE family member 5 Names P antigen family member 5 P antigen family, member 5 (prostate associated) cancer/testis antigen 16.1 cancer/testis antigen family 16, member 1 cancer/testis antigen family 16, member 2 g antigen family E member 1 prostate-associated gene 5 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.21
Summary	This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015].
Disorder MIM:	301009

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013435.2	NP_001013453.1	P antigen family member 5 isoform 2
NM_130467.4	NP_569734.2	P antigen family member 5 isoform 1
NM_001013435.3	NP_001013453.1	P antigen family member 5 isoform 2
NM_130467.5	NP_569734.2	P antigen family member 5 isoform 1

Pathways from BioSystems

Homologies

	PAGE2B	XP_001092373.2
Homo sapiens (human)	PAGE5	NP_569734.2
	LOC695833	XP_001087410.1
Pan troglodytes (chimpanzee)	PAGE5	XP_521084.3

Gene Ontology
Bibliography

Related articles in PubMed

Melanoma-associated cancer-testis antigen 16 (CT16) regulates the expression of apoptotic and antiapoptotic genes and promotes cell survival.
Nylund C, Rappu P, Pakula E, Heino A, Laato L, Elo LL, Vihinen P, Pyrh?nen S, Owen GR, Larjava H, Kallajoki M, Heino J
PloS one7(9)e45382(2012)

Detection of melanoma-derived cancer-testis antigen CT16 in patient sera by a novel immunoassay.
Rappu P, Nylund C, Ristiniemi N, Kulpakko J, Vihinen P, Hernberg M, Mirtti T, Alanen K, Kallajoki M, Vuoristo MS, Pyrh?nen S, Heino J
International journal of cancer128(10)2382-92(2011 May)

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, Songyang Z
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)

Characterization of intrinsically disordered prostate associated gene (PAGE5) at single residue resolution by NMR spectroscopy.
Hellman M, Tossavainen H, Rappu P, Heino J, Permi P
PloS one6(11)e26633(2011)

cDNA microarray analysis of altered gene expression in Ara-C-treated leukemia cells.
Takagaki K, Katsuma S, Horio T, Kaminishi Y, Hada Y, Tanaka T, Ohgi T, Yano J
Biochemical and biophysical research communications309(2)351-8(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate that CT16 promotes the survival of melanoma cells and is therefore a potential target for future drug development.
Title: Melanoma-associated cancer-testis antigen 16 (CT16) regulates the expression of apoptotic and antiapoptotic genes and promotes cell survival.

The following PAGE5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAGE5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29627	NM_001013435.3 Latest version!	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu29687	NM_130467.5 Latest version!	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29627	NM_001013435.2	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu29687	NM_130467.4	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAGE5 ( NM_001013435.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013453.1 Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29627
Clone ID Related Accession (Same CDS sequence)	NM_001013435.2 , NM_001013435.3
Accession Version	NM_001013435.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-20
Organism	Homo sapiens(human)
Product	P antigen family member 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP429046.1 and BQ437151.1. On Jan 13, 2015 this sequence version replaced NM_001013435.1. Transcript Variant: This variant (2) uses an alternate splice site in the 5' region and initiates translation from a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BQ437151.1, BE896256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013453.1
CDS	115..447
Translation	MSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEEPPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPTKVLEAGEGQL

Target ORF information:

RefSeq Version	NM_001013435.2
Organism	Homo sapiens(human)
Definition	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013435.2

ORF Insert Sequence:

ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAGE5 ( NM_001013435.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013453.1 Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29627
Clone ID Related Accession (Same CDS sequence)	NM_001013435.2 , NM_001013435.3
Accession Version	NM_001013435.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	P antigen family member 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158819.14, BP429046.1 and BQ437151.1. On Jul 12, 2018 this sequence version replaced NM_001013435.2. ##Evidence-Data-START## Transcript exon combination :: BG476118.1, BE896256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013453.1
CDS	116..448
Translation	MSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEEPPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPTKVLEAGEGQL

Target ORF information:

RefSeq Version	NM_001013435.3
Organism	Homo sapiens(human)
Definition	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013435.3

ORF Insert Sequence:

ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAGE5 ( NM_130467.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_569734.2 Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29687
Clone ID Related Accession (Same CDS sequence)	NM_130467.4 , NM_130467.5
Accession Version	NM_130467.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-20
Organism	Homo sapiens(human)
Product	P antigen family member 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP429046.1, BC009230.2, AL158819.14 and BQ437151.1. On Jan 13, 2015 this sequence version replaced NM_130467.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BG477487.1, BC009230.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCGC CATGGGCCGG TAATCGTGGC TGGGCTGGAA CGAGGGAGGA AGTGAGAGAT 
ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569734.2
CDS	254..646
Translation	MQAPWAGNRGWAGTREEVRDMSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEEPPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPTKVLEAGEGQL

Target ORF information:

RefSeq Version	NM_130467.4
Organism	Homo sapiens(human)
Definition	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130467.4

ORF Insert Sequence:

ATGCAGGCGC CATGGGCCGG TAATCGTGGC TGGGCTGGAA CGAGGGAGGA AGTGAGAGAT 
ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAGE5 ( NM_130467.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_569734.2 Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29687
Clone ID Related Accession (Same CDS sequence)	NM_130467.4 , NM_130467.5
Accession Version	NM_130467.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	P antigen family member 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158819.14, BP429046.1, BC009230.2 and BQ437151.1. On Jul 12, 2018 this sequence version replaced NM_130467.4. ##Evidence-Data-START## Transcript exon combination :: BG477487.1, BC009230.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCGC CATGGGCCGG TAATCGTGGC TGGGCTGGAA CGAGGGAGGA AGTGAGAGAT 
ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569734.2
CDS	255..647
Translation	MQAPWAGNRGWAGTREEVRDMSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEEPPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPTKVLEAGEGQL

Target ORF information:

RefSeq Version	NM_130467.5
Organism	Homo sapiens(human)
Definition	Homo sapiens PAGE family member 5 (PAGE5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130467.5

ORF Insert Sequence:

ATGCAGGCGC CATGGGCCGG TAATCGTGGC TGGGCTGGAA CGAGGGAGGA AGTGAGAGAT 
ATGAGTGAGC ATGTAACAAG ATCCCAATCC TCAGAAAGAG GAAATGACCA AGAGTCTTCC 
CAGCCAGTTG GACCTGTGAT TGTCCAGCAG CCCACTGAGG AAAAACGTCA AGAAGAGGAA 
CCACCAACTG ATAATCAGGG TATTGCACCT AGTGGGGAGA TCAAAAATGA AGGAGCACCT 
GCTGTTCAAG GGACTGATGT GGAAGCTTTT CAACAGGAAC TGGCTCTGCT TAAGATAGAG 
GATGCACCTG GAGATGGTCC TGATGTCAGG GAGGGGACTC TGCCCACTTT TGATCCCACT 
AAAGTGCTGG AAGCAGGTGA AGGGCAACTA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Melanoma-associated cancer-testis antigen 16 (CT16) regulates the expression of apoptotic and antiapoptotic genes and promotes cell survival.
PloS one7(9)e45382(2012)
Nylund C,Rappu P,Pakula E,Heino A,Laato L,Elo LL,Vihinen P,Pyrh?nen S,Owen GR,Larjava H,Kallajoki M,Heino J

Detection of melanoma-derived cancer-testis antigen CT16 in patient sera by a novel immunoassay.
International journal of cancer128(10)2382-92(2011 May)
Rappu P,Nylund C,Ristiniemi N,Kulpakko J,Vihinen P,Hernberg M,Mirtti T,Alanen K,Kallajoki M,Vuoristo MS,Pyrh?nen S,Heino J

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)
Lee OH,Kim H,He Q,Baek HJ,Yang D,Chen LY,Liang J,Chae HK,Safari A,Liu D,Songyang Z

Characterization of intrinsically disordered prostate associated gene (PAGE5) at single residue resolution by NMR spectroscopy.
PloS one6(11)e26633(2011)
Hellman M,Tossavainen H,Rappu P,Heino J,Permi P

cDNA microarray analysis of altered gene expression in Ara-C-treated leukemia cells.
Biochemical and biophysical research communications309(2)351-8(2003 Sep)
Takagaki K,Katsuma S,Horio T,Kaminishi Y,Hada Y,Tanaka T,Ohgi T,Yano J

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PAGE5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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