Gene Symbol | CACNA1G |
Entrez Gene ID | 8913 |
Full Name | calcium voltage-gated channel subunit alpha1 G |
Synonyms | Ca(V)T.1,Cav3.1,NBR13,SCA42 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]. |
Disorder MIM: | |
Disorder Html: | Spinocerebellar ataxia 42, 616795 (3) |