UNC5C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UNC5C
Entrez Gene ID	8633
Full Name	unc-5 netrin receptor C
Synonyms	UNC5H3
General protein information	Preferred Names unc-5 netrin receptor C Names netrin receptor UNC5C protein unc-5 homolog 3 protein unc-5 homolog C unc-5 homolog 3 unc-5 homolog C unc5 (C.elegans homolog) c
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q22.3
Summary	This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008].
Disorder MIM:	603610

mRNA and Protein(s)

mRNA	Protein	Name
XM_005263321.3	XP_005263378.1	netrin receptor UNC5C isoform X1
NM_003728.4	NP_003719.3	netrin receptor UNC5C
XM_017008789.1	XP_016864278.1	netrin receptor UNC5C isoform X2
NM_003728.3	NP_003719.3	netrin receptor UNC5C precursor
XM_017008790.1	XP_016864279.1	netrin receptor UNC5C isoform X2

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	unc5c	XP_004911160.1
Pan troglodytes (chimpanzee)	UNC5C	XP_526636.2
	UNC5C	XP_002804202.1
Gallus gallus (chicken)	UNC5C	NP_989782.1
Danio rerio (zebrafish)	unc5c	NP_001093454.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009061	XP_319812.4
Homo sapiens (human)	UNC5C	NP_003719.3
Canis lupus familiaris (dog)	UNC5C	XP_005639270.1
Bos taurus (cattle)	UNC5C	XP_005207793.1
Rattus norvegicus (Norway rat)	Unc5c	NP_955439.1
Drosophila melanogaster (fruit fly)	unc-5	NP_611033.2
Mus musculus (house mouse)	Unc5c	NP_033498.1

Gene Ontology
Bibliography

Related articles in PubMed

Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion.
Shao Q, Yang T, Huang H, Alarmanazi F, Liu G
The Journal of neuroscience : the official journal of the Society for Neuroscience37(23)5620-5633(2017 Jun)

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL
PLoS medicine14(4)e1002287(2017 Apr)

Methylation of the UNC5C gene and its protein expression in colorectal cancer.
Wu J, Wang G, He B, Chen X, An Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(4)1010428317697564(2017 Apr)

An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid ? Precursor Protein Signaling.
Hashimoto Y, Toyama Y, Kusakari S, Nawa M, Matsuoka M
The Journal of biological chemistry291(23)12282-93(2016 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we identified ENC1 and UNC5C as genes with convergent genetic, epigenetic, and transcriptomic evidence supporting a potential role in the dissociation of cognition and neuropathology in an aging population.
Title: Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.

the results suggest that UNC5C methylation may be an earlier event in the development of colorectal cancer, which was negatively correlated with protein expression.
Title: Methylation of the UNC5C gene and its protein expression in colorectal cancer.

Data show that overexpression of wild-type netrin receptor UNC5C (UNC5C) causes low-grade death, which is intensified by an Alzheimer Disease-linked mutation T835M, and mediated by amyloid beta precursor protein (APP).
Title: An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid ? Precursor Protein Signaling.

7 of these 8 variants do not cause increased colorectal cancer risk, including UNC5C c.1882_1883delinsAA (p.A628K).
Title: Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis.

identify the V-2 domain of netrin-1 to be important for its interaction with the Ig1/Ig2 domains of UNC5H2
Title: Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.

The following UNC5C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UNC5C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32255	NM_003728.3 Latest version!	Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu39196	XM_005263321.3 Latest version!	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu107506	NM_003728.4 Latest version!	Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu95521	XM_017008789.1 Latest version!	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu95521	XM_017008790.1 Latest version!	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UNC5C ( NM_003728.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003719.3 Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.

Price & Availability↑

CloneID	OHu32255
Clone ID Related Accession (Same CDS sequence)	NM_003728.3
Accession Version	NM_003728.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	netrin receptor UNC5C precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106881.9, AK290500.1, AF055634.1 and AC105395.1. On Jul 31, 2010 this sequence version replaced NM_003728.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.228788.1, SRR1660803.132071.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCTGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGACT GCTCCTGATT CAGATGATGT TGCTCTCTAT 
GTTGGGATTG TGATAGCAGT GATCGTTTGC CTGGCGATCT CTGTAGTTGT GGCCTTGTTT 
GTGTATCGGA AGAATCATCG TGACTTTGAG TCAGATATTA TTGACTCTTC GGCACTCAAT 
GGGGGCTTTC AGCCTGTGAA CATCAAGGCA GCAAGACAAG ATCTGCTGGC TGTACCCCCA 
GACCTCACGT CAGCTGCAGC CATGTACAGA GGACCTGTCT ATGCCCTGCA TGACGTCTCA 
GACAAAATCC CAATGACCAA CTCTCCAATT CTGGATCCAC TGCCCAACCT GAAAATCAAA 
GTGTACAACA CCTCAGGTGC TGTCACCCCC CAAGATGACC TCTCTGAGTT TACGTCCAAG 
CTGTCCCCTC AGATGACCCA GTCGTTGTTG GAGAATGAAG CCCTCAGCCT GAAGAACCAG 
AGTCTAGCAA GGCAGACTGA TCCATCCTGT ACCGCATTTG GCAGCTTCAA CTCGCTGGGA 
GGTCACCTTA TTGTTCCCAA TTCAGGAGTC AGCTTGCTGA TTCCCGCTGG GGCCATTCCC 
CAAGGGAGAG TCTACGAAAT GTATGTGACT GTACACAGGA AAGAAACTAT GAGGCCACCC 
ATGGATGACT CTCAGACACT TTTGACCCCT GTGGTGAGCT GTGGGCCCCC AGGAGCTCTG 
CTCACCCGCC CAGTCGTCCT CACTATGCAT CACTGCGCAG ACCCCAATAC CGAGGACTGG 
AAAATACTGC TCAAGAACCA GGCAGCACAG GGACAGTGGG AGGATGTGGT GGTGGTCGGG 
GAGGAAAACT TCACCACCCC CTGCTACATT CAGCTGGATG CAGAGGCCTG CCACATCCTC 
ACAGAGAACC TCAGCACCTA CGCCCTGGTA GGACATTCCA CCACCAAAGC GGCTGCGAAG 
CGCCTCAAGC TGGCCATCTT TGGGCCCCTG TGCTGCTCCT CGCTGGAGTA CAGCATCCGA 
GTCTACTGTC TGGATGACAC CCAGGATGCC CTGAAGGAAA TTTTACATCT TGAGAGACAG 
ATGGGAGGAC AGCTCCTAGA AGAACCTAAG GCTCTTCATT TTAAAGGCAG CACCCACAAC 
CTGCGCCTGT CAATTCACGA TATCGCCCAT TCCCTCTGGA AGAGCAAATT GCTGGCTAAA 
TATCAGGAAA TTCCATTTTA CCATGTTTGG AGTGGATCTC AAAGAAACCT GCACTGCACC 
TTCACTCTGG AAAGATTTAG CCTGAACACA GTGGAGCTGG TTTGCAAACT CTGTGTGCGG 
CAGGTGGAAG GAGAAGGGCA GATCTTCCAG CTCAACTGCA CCGTGTCAGA GGAACCTACT 
GGCATCGATT TGCCGCTGCT GGATCCTGCG AACACCATCA CCACGGTCAC GGGGCCCAGT 
GCTTTCAGCA TCCCTCTCCC TATCCGGCAG AAGCTCTGTA GCAGCCTGGA TGCCCCCCAG 
ACGAGAGGCC ATGACTGGAG GATGCTGGCC CATAAGCTGA ACCTGGACAG GTACTTGAAT 
TACTTTGCCA CCAAATCCAG CCCAACTGGC GTAATCCTGG ATCTTTGGGA AGCACAGAAC 
TTCCCAGATG GAAACCTGAG CATGCTGGCA GCTGTCTTGG AAGAAATGGG AAGACATGAA 
ACGGTGGTGT CCTTAGCAGC AGAAGGGCAG TATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003719.3
CDS	354..3149
Translation	MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

Target ORF information:

RefSeq Version	NM_003728.3
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003728.3

ORF Insert Sequence:

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCTGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGACT GCTCCTGATT CAGATGATGT TGCTCTCTAT 
GTTGGGATTG TGATAGCAGT GATCGTTTGC CTGGCGATCT CTGTAGTTGT GGCCTTGTTT 
GTGTATCGGA AGAATCATCG TGACTTTGAG TCAGATATTA TTGACTCTTC GGCACTCAAT 
GGGGGCTTTC AGCCTGTGAA CATCAAGGCA GCAAGACAAG ATCTGCTGGC TGTACCCCCA 
GACCTCACGT CAGCTGCAGC CATGTACAGA GGACCTGTCT ATGCCCTGCA TGACGTCTCA 
GACAAAATCC CAATGACCAA CTCTCCAATT CTGGATCCAC TGCCCAACCT GAAAATCAAA 
GTGTACAACA CCTCAGGTGC TGTCACCCCC CAAGATGACC TCTCTGAGTT TACGTCCAAG 
CTGTCCCCTC AGATGACCCA GTCGTTGTTG GAGAATGAAG CCCTCAGCCT GAAGAACCAG 
AGTCTAGCAA GGCAGACTGA TCCATCCTGT ACCGCATTTG GCAGCTTCAA CTCGCTGGGA 
GGTCACCTTA TTGTTCCCAA TTCAGGAGTC AGCTTGCTGA TTCCCGCTGG GGCCATTCCC 
CAAGGGAGAG TCTACGAAAT GTATGTGACT GTACACAGGA AAGAAACTAT GAGGCCACCC 
ATGGATGACT CTCAGACACT TTTGACCCCT GTGGTGAGCT GTGGGCCCCC AGGAGCTCTG 
CTCACCCGCC CAGTCGTCCT CACTATGCAT CACTGCGCAG ACCCCAATAC CGAGGACTGG 
AAAATACTGC TCAAGAACCA GGCAGCACAG GGACAGTGGG AGGATGTGGT GGTGGTCGGG 
GAGGAAAACT TCACCACCCC CTGCTACATT CAGCTGGATG CAGAGGCCTG CCACATCCTC 
ACAGAGAACC TCAGCACCTA CGCCCTGGTA GGACATTCCA CCACCAAAGC GGCTGCGAAG 
CGCCTCAAGC TGGCCATCTT TGGGCCCCTG TGCTGCTCCT CGCTGGAGTA CAGCATCCGA 
GTCTACTGTC TGGATGACAC CCAGGATGCC CTGAAGGAAA TTTTACATCT TGAGAGACAG 
ATGGGAGGAC AGCTCCTAGA AGAACCTAAG GCTCTTCATT TTAAAGGCAG CACCCACAAC 
CTGCGCCTGT CAATTCACGA TATCGCCCAT TCCCTCTGGA AGAGCAAATT GCTGGCTAAA 
TATCAGGAAA TTCCATTTTA CCATGTTTGG AGTGGATCTC AAAGAAACCT GCACTGCACC 
TTCACTCTGG AAAGATTTAG CCTGAACACA GTGGAGCTGG TTTGCAAACT CTGTGTGCGG 
CAGGTGGAAG GAGAAGGGCA GATCTTCCAG CTCAACTGCA CCGTGTCAGA GGAACCTACT 
GGCATCGATT TGCCGCTGCT GGATCCTGCG AACACCATCA CCACGGTCAC GGGGCCCAGT 
GCTTTCAGCA TCCCTCTCCC TATCCGGCAG AAGCTCTGTA GCAGCCTGGA TGCCCCCCAG 
ACGAGAGGCC ATGACTGGAG GATGCTGGCC CATAAGCTGA ACCTGGACAG GTACTTGAAT 
TACTTTGCCA CCAAATCCAG CCCAACTGGC GTAATCCTGG ATCTTTGGGA AGCACAGAAC 
TTCCCAGATG GAAACCTGAG CATGCTGGCA GCTGTCTTGG AAGAAATGGG AAGACATGAA 
ACGGTGGTGT CCTTAGCAGC AGAAGGGCAG TATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC5C ( XM_005263321.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005263378.1 Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu39196
Clone ID Related Accession (Same CDS sequence)	XM_005263321.3
Accession Version	XM_005263321.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	netrin receptor UNC5C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005263321.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCCGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGAGT TTCATTTATC CCATTTCAAC TGAACAGAGA 
ACCCAGAATG AATATGGATT TTCTTCTGCT CCTGATTCAG ATGATGTTGC TCTCTATGTT 
GGGATTGTGA TAGCAGTGAT CGTTTGCCTG GCGATCTCTG TAGTTGTGGC CTTGTTTGTG 
TATCGGAAGA ATCATCGTGA CTTTGAGTCA GATATTATTG ACTCTTCGGC ACTCAATGGG 
GGCTTTCAGC CTGTGAACAT CAAGGCAGCA AGACAAGATC TGCTGGCTGT ACCCCCAGAC 
CTCACGTCAG CTGCAGCCAT GTACAGAGGA CCTGTCTATG CCCTGCATGA CGTCTCAGAC 
AAAATCCCAA TGACCAACTC TCCAATTCTG GATCCACTGC CCAACCTGAA AATCAAAGTG 
TACAACACCT CAGGTGCTGT CACCCCCCAA GATGACCTCT CTGAGTTTAC GTCCAAGCTG 
TCCCCTCAGA TGACCCAGTC GTTGTTGGAG AATGAAGCCC TCAGCCTGAA GAACCAGAGT 
CTAGCAAGGC AGACTGATCC ATCCTGTACC GCATTTGGCA GCTTCAACTC GCTGGGAGGT 
CACCTTATTG TTCCCAATTC AGGAGTCAGC TTGCTGATTC CCGCTGGGGC CATTCCCCAA 
GGGAGAGTCT ACGAAATGTA TGTGACTGTA CACAGGAAAG AAACTATGAG GCCACCCATG 
GATGACTCTC AGACACTTTT GACCCCTGTG GTGAGCTGTG GGCCCCCAGG AGCTCTGCTC 
ACCCGCCCAG TCGTCCTCAC TATGCATCAC TGCGCAGACC CCAATACCGA GGACTGGAAA 
ATACTGCTCA AGAACCAGGC AGCACAGGGA CAGTGGGAGG ATGTGGTGGT GGTCGGGGAG 
GAAAACTTCA CCACCCCCTG CTACATTCAG CTGGATGCAG AGGCCTGCCA CATCCTCACA 
GAGAACCTCA GCACCTACGC CCTGGTAGGA CATTCCACCA CCAAAGCGGC TGCGAAGCGC 
CTCAAGCTGG CCATCTTTGG GCCCCTGTGC TGCTCCTCGC TGGAGTACAG CATCCGAGTC 
TACTGTCTGG ATGACACCCA GGATGCCCTG AAGGAAATTT TACATCTTGA GAGACAGATG 
GGAGGACAGC TCCTAGAAGA ACCTAAGGCT CTTCATTTTA AAGGCAGCAC CCACAACCTG 
CGCCTGTCAA TTCACGATAT CGCCCATTCC CTCTGGAAGA GCAAATTGCT GGCTAAATAT 
CAGGAAATTC CATTTTACCA TGTTTGGAGT GGATCTCAAA GAAACCTGCA CTGCACCTTC 
ACTCTGGAAA GATTTAGCCT GAACACAGTG GAGCTGGTTT GCAAACTCTG TGTGCGGCAG 
GTGGAAGGAG AAGGGCAGAT CTTCCAGCTC AACTGCACCG TGTCAGAGGA ACCTACTGGC 
ATCGATTTGC CGCTGCTGGA TCCTGCGAAC ACCATCACCA CGGTCACGGG GCCCAGTGCT 
TTCAGCATCC CTCTCCCTAT CCGGCAGAAG CTCTGTAGCA GCCTGGATGC CCCCCAGACG 
AGAGGCCATG ACTGGAGGAT GCTGGCCCAT AAGCTGAACC TGGACAGGTA CTTGAATTAC 
TTTGCCACCA AATCCAGCCC AACTGGCGTA ATCCTGGATC TTTGGGAAGC ACAGAACTTC 
CCAGATGGAA ACCTGAGCAT GCTGGCAGCT GTCTTGGAAG AAATGGGAAG ACATGAAACG 
GTGGTGTCCT TAGCAGCAGA AGGGCAGTAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005263378.1
CDS	354..3206
Translation	MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQSFIYPISTEQRTQNEYGFSSAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

Target ORF information:

RefSeq Version	XM_005263321.3
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005263321.3

ORF Insert Sequence:

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCCGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGAGT TTCATTTATC CCATTTCAAC TGAACAGAGA 
ACCCAGAATG AATATGGATT TTCTTCTGCT CCTGATTCAG ATGATGTTGC TCTCTATGTT 
GGGATTGTGA TAGCAGTGAT CGTTTGCCTG GCGATCTCTG TAGTTGTGGC CTTGTTTGTG 
TATCGGAAGA ATCATCGTGA CTTTGAGTCA GATATTATTG ACTCTTCGGC ACTCAATGGG 
GGCTTTCAGC CTGTGAACAT CAAGGCAGCA AGACAAGATC TGCTGGCTGT ACCCCCAGAC 
CTCACGTCAG CTGCAGCCAT GTACAGAGGA CCTGTCTATG CCCTGCATGA CGTCTCAGAC 
AAAATCCCAA TGACCAACTC TCCAATTCTG GATCCACTGC CCAACCTGAA AATCAAAGTG 
TACAACACCT CAGGTGCTGT CACCCCCCAA GATGACCTCT CTGAGTTTAC GTCCAAGCTG 
TCCCCTCAGA TGACCCAGTC GTTGTTGGAG AATGAAGCCC TCAGCCTGAA GAACCAGAGT 
CTAGCAAGGC AGACTGATCC ATCCTGTACC GCATTTGGCA GCTTCAACTC GCTGGGAGGT 
CACCTTATTG TTCCCAATTC AGGAGTCAGC TTGCTGATTC CCGCTGGGGC CATTCCCCAA 
GGGAGAGTCT ACGAAATGTA TGTGACTGTA CACAGGAAAG AAACTATGAG GCCACCCATG 
GATGACTCTC AGACACTTTT GACCCCTGTG GTGAGCTGTG GGCCCCCAGG AGCTCTGCTC 
ACCCGCCCAG TCGTCCTCAC TATGCATCAC TGCGCAGACC CCAATACCGA GGACTGGAAA 
ATACTGCTCA AGAACCAGGC AGCACAGGGA CAGTGGGAGG ATGTGGTGGT GGTCGGGGAG 
GAAAACTTCA CCACCCCCTG CTACATTCAG CTGGATGCAG AGGCCTGCCA CATCCTCACA 
GAGAACCTCA GCACCTACGC CCTGGTAGGA CATTCCACCA CCAAAGCGGC TGCGAAGCGC 
CTCAAGCTGG CCATCTTTGG GCCCCTGTGC TGCTCCTCGC TGGAGTACAG CATCCGAGTC 
TACTGTCTGG ATGACACCCA GGATGCCCTG AAGGAAATTT TACATCTTGA GAGACAGATG 
GGAGGACAGC TCCTAGAAGA ACCTAAGGCT CTTCATTTTA AAGGCAGCAC CCACAACCTG 
CGCCTGTCAA TTCACGATAT CGCCCATTCC CTCTGGAAGA GCAAATTGCT GGCTAAATAT 
CAGGAAATTC CATTTTACCA TGTTTGGAGT GGATCTCAAA GAAACCTGCA CTGCACCTTC 
ACTCTGGAAA GATTTAGCCT GAACACAGTG GAGCTGGTTT GCAAACTCTG TGTGCGGCAG 
GTGGAAGGAG AAGGGCAGAT CTTCCAGCTC AACTGCACCG TGTCAGAGGA ACCTACTGGC 
ATCGATTTGC CGCTGCTGGA TCCTGCGAAC ACCATCACCA CGGTCACGGG GCCCAGTGCT 
TTCAGCATCC CTCTCCCTAT CCGGCAGAAG CTCTGTAGCA GCCTGGATGC CCCCCAGACG 
AGAGGCCATG ACTGGAGGAT GCTGGCCCAT AAGCTGAACC TGGACAGGTA CTTGAATTAC 
TTTGCCACCA AATCCAGCCC AACTGGCGTA ATCCTGGATC TTTGGGAAGC ACAGAACTTC 
CCAGATGGAA ACCTGAGCAT GCTGGCAGCT GTCTTGGAAG AAATGGGAAG ACATGAAACG 
GTGGTGTCCT TAGCAGCAGA AGGGCAGTAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC5C ( NM_003728.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003719.3 Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.

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CloneID	OHu107506
Clone ID Related Accession (Same CDS sequence)	NM_003728.4
Accession Version	NM_003728.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-07
Organism	Homo sapiens(human)
Product	netrin receptor UNC5C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106881.9, AC098584.2 and AC105395.1. On Nov 23, 2018 this sequence version replaced NM_003728.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.228788.1, SRR1660803.132071.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000453304.6/ ENSP00000406022.1 RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCCGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGACT GCTCCTGATT CAGATGATGT TGCTCTCTAT 
GTTGGGATTG TGATAGCAGT GATCGTTTGC CTGGCGATCT CTGTAGTTGT GGCCTTGTTT 
GTGTATCGGA AGAATCATCG TGACTTTGAG TCAGATATTA TTGACTCTTC GGCACTCAAT 
GGGGGCTTTC AGCCTGTGAA CATCAAGGCA GCAAGACAAG ATCTGCTGGC TGTACCCCCA 
GACCTCACGT CAGCTGCAGC CATGTACAGA GGACCTGTCT ATGCCCTGCA TGACGTCTCA 
GACAAAATCC CAATGACCAA CTCTCCAATT CTGGATCCAC TGCCCAACCT GAAAATCAAA 
GTGTACAACA CCTCAGGTGC TGTCACCCCC CAAGATGACC TCTCTGAGTT TACGTCCAAG 
CTGTCCCCTC AGATGACCCA GTCGTTGTTG GAGAATGAAG CCCTCAGCCT GAAGAACCAG 
AGTCTAGCAA GGCAGACTGA TCCATCCTGT ACCGCATTTG GCAGCTTCAA CTCGCTGGGA 
GGTCACCTTA TTGTTCCCAA TTCAGGAGTC AGCTTGCTGA TTCCCGCTGG GGCCATTCCC 
CAAGGGAGAG TCTACGAAAT GTATGTGACT GTACACAGGA AAGAAACTAT GAGGCCACCC 
ATGGATGACT CTCAGACACT TTTGACCCCT GTGGTGAGCT GTGGGCCCCC AGGAGCTCTG 
CTCACCCGCC CAGTCGTCCT CACTATGCAT CACTGCGCAG ACCCCAATAC CGAGGACTGG 
AAAATACTGC TCAAGAACCA GGCAGCACAG GGACAGTGGG AGGATGTGGT GGTGGTCGGG 
GAGGAAAACT TCACCACCCC CTGCTACATT CAGCTGGATG CAGAGGCCTG CCACATCCTC 
ACAGAGAACC TCAGCACCTA CGCCCTGGTA GGACATTCCA CCACCAAAGC GGCTGCGAAG 
CGCCTCAAGC TGGCCATCTT TGGGCCCCTG TGCTGCTCCT CGCTGGAGTA CAGCATCCGA 
GTCTACTGTC TGGATGACAC CCAGGATGCC CTGAAGGAAA TTTTACATCT TGAGAGACAG 
ATGGGAGGAC AGCTCCTAGA AGAACCTAAG GCTCTTCATT TTAAAGGCAG CACCCACAAC 
CTGCGCCTGT CAATTCACGA TATCGCCCAT TCCCTCTGGA AGAGCAAATT GCTGGCTAAA 
TATCAGGAAA TTCCATTTTA CCATGTTTGG AGTGGATCTC AAAGAAACCT GCACTGCACC 
TTCACTCTGG AAAGATTTAG CCTGAACACA GTGGAGCTGG TTTGCAAACT CTGTGTGCGG 
CAGGTGGAAG GAGAAGGGCA GATCTTCCAG CTCAACTGCA CCGTGTCAGA GGAACCTACT 
GGCATCGATT TGCCGCTGCT GGATCCTGCG AACACCATCA CCACGGTCAC GGGGCCCAGT 
GCTTTCAGCA TCCCTCTCCC TATCCGGCAG AAGCTCTGTA GCAGCCTGGA TGCCCCCCAG 
ACGAGAGGCC ATGACTGGAG GATGCTGGCC CATAAGCTGA ACCTGGACAG GTACTTGAAT 
TACTTTGCCA CCAAATCCAG CCCAACTGGC GTAATCCTGG ATCTTTGGGA AGCACAGAAC 
TTCCCAGATG GAAACCTGAG CATGCTGGCA GCTGTCTTGG AAGAAATGGG AAGACATGAA 
ACGGTGGTGT CCTTAGCAGC AGAAGGGCAG TATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003719.3
CDS	117..2912
Translation	MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

Target ORF information:

RefSeq Version	NM_003728.4
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-5 netrin receptor C (UNC5C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003728.4

ORF Insert Sequence:

ATGAGGAAAG GTCTGCGGGC GACAGCGGCC CGCTGCGGAC TGGGACTGGG ATACTTGCTG 
CAAATGCTCG TGCTACCTGC CCTGGCCCTG CTCAGCGCCA GCGGCACTGG CTCCGCCGCC 
CAAGATGATG ACTTTTTTCA TGAACTCCCA GAAACTTTTC CTTCTGATCC ACCTGAGCCT 
CTGCCACATT TCCTTATTGA GCCTGAAGAA GCTTATATTG TGAAGAATAA GCCCGTGAAC 
CTGTACTGTA AAGCAAGCCC TGCCACCCAG ATCTATTTCA AGTGTAATAG TGAATGGGTT 
CATCAGAAGG ACCACATAGT AGATGAAAGA GTAGATGAAA CTTCCGGTCT CATTGTCCGG 
GAAGTGAGCA TTGAGATTTC GCGCCAGCAA GTGGAAGAAC TCTTTGGACC TGAAGATTAC 
TGGTGCCAGT GTGTGGCCTG GAGCTCCGCG GGTACCACAA AGAGCCGGAA GGCGTATGTG 
CGCATTGCAT ATCTACGGAA GACATTTGAG CAGGAACCCC TAGGAAAGGA AGTGTCTTTG 
GAACAGGAAG TCTTACTCCA GTGTCGACCA CCTGAAGGGA TCCCAGTGGC TGAGGTGGAA 
TGGTTGAAAA ATGAAGACAT AATTGATCCC GTTGAAGATC GGAATTTTTA TATTACTATT 
GATCACAACC TCATCATAAA GCAGGCCCGA CTCTCTGATA CTGCAAATTA CACCTGTGTT 
GCCAAAAACA TTGTTGCCAA GAGGAAAAGT ACAACTGCCA CTGTCATAGT CTATGTCAAC 
GGTGGCTGGT CCACCTGGAC GGAGTGGTCT GTGTGTAACA GCCGCTGTGG ACGAGGGTAT 
CAGAAACGTA CAAGGACTTG TACCAACCCG GCACCACTCA ATGGGGGTGC CTTCTGTGAA 
GGGCAGAGTG TGCAGAAAAT AGCCTGTACT ACGTTATGCC CAGTGGATGG CAGGTGGACG 
CCATGGAGCA AGTGGTCTAC TTGTGGAACT GAGTGCACCC ACTGGCGCAG GAGGGAGTGC 
ACGGCGCCAG CCCCCAAGAA TGGAGGCAAG GACTGCGACG GCCTCGTCTT GCAATCCAAG 
AACTGCACTG ATGGGCTTTG CATGCAGACT GCTCCTGATT CAGATGATGT TGCTCTCTAT 
GTTGGGATTG TGATAGCAGT GATCGTTTGC CTGGCGATCT CTGTAGTTGT GGCCTTGTTT 
GTGTATCGGA AGAATCATCG TGACTTTGAG TCAGATATTA TTGACTCTTC GGCACTCAAT 
GGGGGCTTTC AGCCTGTGAA CATCAAGGCA GCAAGACAAG ATCTGCTGGC TGTACCCCCA 
GACCTCACGT CAGCTGCAGC CATGTACAGA GGACCTGTCT ATGCCCTGCA TGACGTCTCA 
GACAAAATCC CAATGACCAA CTCTCCAATT CTGGATCCAC TGCCCAACCT GAAAATCAAA 
GTGTACAACA CCTCAGGTGC TGTCACCCCC CAAGATGACC TCTCTGAGTT TACGTCCAAG 
CTGTCCCCTC AGATGACCCA GTCGTTGTTG GAGAATGAAG CCCTCAGCCT GAAGAACCAG 
AGTCTAGCAA GGCAGACTGA TCCATCCTGT ACCGCATTTG GCAGCTTCAA CTCGCTGGGA 
GGTCACCTTA TTGTTCCCAA TTCAGGAGTC AGCTTGCTGA TTCCCGCTGG GGCCATTCCC 
CAAGGGAGAG TCTACGAAAT GTATGTGACT GTACACAGGA AAGAAACTAT GAGGCCACCC 
ATGGATGACT CTCAGACACT TTTGACCCCT GTGGTGAGCT GTGGGCCCCC AGGAGCTCTG 
CTCACCCGCC CAGTCGTCCT CACTATGCAT CACTGCGCAG ACCCCAATAC CGAGGACTGG 
AAAATACTGC TCAAGAACCA GGCAGCACAG GGACAGTGGG AGGATGTGGT GGTGGTCGGG 
GAGGAAAACT TCACCACCCC CTGCTACATT CAGCTGGATG CAGAGGCCTG CCACATCCTC 
ACAGAGAACC TCAGCACCTA CGCCCTGGTA GGACATTCCA CCACCAAAGC GGCTGCGAAG 
CGCCTCAAGC TGGCCATCTT TGGGCCCCTG TGCTGCTCCT CGCTGGAGTA CAGCATCCGA 
GTCTACTGTC TGGATGACAC CCAGGATGCC CTGAAGGAAA TTTTACATCT TGAGAGACAG 
ATGGGAGGAC AGCTCCTAGA AGAACCTAAG GCTCTTCATT TTAAAGGCAG CACCCACAAC 
CTGCGCCTGT CAATTCACGA TATCGCCCAT TCCCTCTGGA AGAGCAAATT GCTGGCTAAA 
TATCAGGAAA TTCCATTTTA CCATGTTTGG AGTGGATCTC AAAGAAACCT GCACTGCACC 
TTCACTCTGG AAAGATTTAG CCTGAACACA GTGGAGCTGG TTTGCAAACT CTGTGTGCGG 
CAGGTGGAAG GAGAAGGGCA GATCTTCCAG CTCAACTGCA CCGTGTCAGA GGAACCTACT 
GGCATCGATT TGCCGCTGCT GGATCCTGCG AACACCATCA CCACGGTCAC GGGGCCCAGT 
GCTTTCAGCA TCCCTCTCCC TATCCGGCAG AAGCTCTGTA GCAGCCTGGA TGCCCCCCAG 
ACGAGAGGCC ATGACTGGAG GATGCTGGCC CATAAGCTGA ACCTGGACAG GTACTTGAAT 
TACTTTGCCA CCAAATCCAG CCCAACTGGC GTAATCCTGG ATCTTTGGGA AGCACAGAAC 
TTCCCAGATG GAAACCTGAG CATGCTGGCA GCTGTCTTGG AAGAAATGGG AAGACATGAA 
ACGGTGGTGT CCTTAGCAGC AGAAGGGCAG TATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC5C ( XM_017008789.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864278.1 Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X2, mRNA.

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CloneID	OHu95521
Clone ID Related Accession (Same CDS sequence)	XM_017008789.1 , XM_017008790.1
Accession Version	XM_017008789.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1695bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	netrin receptor UNC5C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGACTG CTCCTGATTC AGATGATGTT GCTCTCTATG TTGGGATTGT GATAGCAGTG 
ATCGTTTGCC TGGCGATCTC TGTAGTTGTG GCCTTGTTTG TGTATCGGAA GAATCATCGT 
GACTTTGAGT CAGATATTAT TGACTCTTCG GCACTCAATG GGGGCTTTCA GCCTGTGAAC 
ATCAAGGCAG CAAGACAAGA TCTGCTGGCT GTACCCCCAG ACCTCACGTC AGCTGCAGCC 
ATGTACAGAG GACCTGTCTA TGCCCTGCAT GACGTCTCAG ACAAAATCCC AATGACCAAC 
TCTCCAATTC TGGATCCACT GCCCAACCTG AAAATCAAAG TGTACAACAC CTCAGGTGCT 
GTCACCCCCC AAGATGACCT CTCTGAGTTT ACGTCCAAGC TGTCCCCTCA GATGACCCAG 
TCGTTGTTGG AGAATGAAGC CCTCAGCCTG AAGAACCAGA GTCTAGCAAG GCAGACTGAT 
CCATCCTGTA CCGCATTTGG CAGCTTCAAC TCGCTGGGAG GTCACCTTAT TGTTCCCAAT 
TCAGGAGTCA GCTTGCTGAT TCCCGCTGGG GCCATTCCCC AAGGGAGAGT CTACGAAATG 
TATGTGACTG TACACAGGAA AGAAACTATG AGGCCACCCA TGGATGACTC TCAGACACTT 
TTGACCCCTG TGGTGAGCTG TGGGCCCCCA GGAGCTCTGC TCACCCGCCC AGTCGTCCTC 
ACTATGCATC ACTGCGCAGA CCCCAATACC GAGGACTGGA AAATACTGCT CAAGAACCAG 
GCAGCACAGG GACAGTGGGA GGATGTGGTG GTGGTCGGGG AGGAAAACTT CACCACCCCC 
TGCTACATTC AGCTGGATGC AGAGGCCTGC CACATCCTCA CAGAGAACCT CAGCACCTAC 
GCCCTGGTAG GACATTCCAC CACCAAAGCG GCTGCGAAGC GCCTCAAGCT GGCCATCTTT 
GGGCCCCTGT GCTGCTCCTC GCTGGAGTAC AGCATCCGAG TCTACTGTCT GGATGACACC 
CAGGATGCCC TGAAGGAAAT TTTACATCTT GAGAGACAGA TGGGAGGACA GCTCCTAGAA 
GAACCTAAGG CTCTTCATTT TAAAGGCAGC ACCCACAACC TGCGCCTGTC AATTCACGAT 
ATCGCCCATT CCCTCTGGAA GAGCAAATTG CTGGCTAAAT ATCAGGAAAT TCCATTTTAC 
CATGTTTGGA GTGGATCTCA AAGAAACCTG CACTGCACCT TCACTCTGGA AAGATTTAGC 
CTGAACACAG TGGAGCTGGT TTGCAAACTC TGTGTGCGGC AGGTGGAAGG AGAAGGGCAG 
ATCTTCCAGC TCAACTGCAC CGTGTCAGAG GAACCTACTG GCATCGATTT GCCGCTGCTG 
GATCCTGCGA ACACCATCAC CACGGTCACG GGGCCCAGTG CTTTCAGCAT CCCTCTCCCT 
ATCCGGCAGA AGCTCTGTAG CAGCCTGGAT GCCCCCCAGA CGAGAGGCCA TGACTGGAGG 
ATGCTGGCCC ATAAGCTGAA CCTGGACAGG TACTTGAATT ACTTTGCCAC CAAATCCAGC 
CCAACTGGCG TAATCCTGGA TCTTTGGGAA GCACAGAACT TCCCAGATGG AAACCTGAGC 
ATGCTGGCAG CTGTCTTGGA AGAAATGGGA AGACATGAAA CGGTGGTGTC CTTAGCAGCA 
GAAGGGCAGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864278.1
CDS	7872..9566
Translation	MQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

Target ORF information:

RefSeq Version	XM_017008789.1
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008789.1

ORF Insert Sequence:

ATGCAGACTG CTCCTGATTC AGATGATGTT GCTCTCTATG TTGGGATTGT GATAGCAGTG 
ATCGTTTGCC TGGCGATCTC TGTAGTTGTG GCCTTGTTTG TGTATCGGAA GAATCATCGT 
GACTTTGAGT CAGATATTAT TGACTCTTCG GCACTCAATG GGGGCTTTCA GCCTGTGAAC 
ATCAAGGCAG CAAGACAAGA TCTGCTGGCT GTACCCCCAG ACCTCACGTC AGCTGCAGCC 
ATGTACAGAG GACCTGTCTA TGCCCTGCAT GACGTCTCAG ACAAAATCCC AATGACCAAC 
TCTCCAATTC TGGATCCACT GCCCAACCTG AAAATCAAAG TGTACAACAC CTCAGGTGCT 
GTCACCCCCC AAGATGACCT CTCTGAGTTT ACGTCCAAGC TGTCCCCTCA GATGACCCAG 
TCGTTGTTGG AGAATGAAGC CCTCAGCCTG AAGAACCAGA GTCTAGCAAG GCAGACTGAT 
CCATCCTGTA CCGCATTTGG CAGCTTCAAC TCGCTGGGAG GTCACCTTAT TGTTCCCAAT 
TCAGGAGTCA GCTTGCTGAT TCCCGCTGGG GCCATTCCCC AAGGGAGAGT CTACGAAATG 
TATGTGACTG TACACAGGAA AGAAACTATG AGGCCACCCA TGGATGACTC TCAGACACTT 
TTGACCCCTG TGGTGAGCTG TGGGCCCCCA GGAGCTCTGC TCACCCGCCC AGTCGTCCTC 
ACTATGCATC ACTGCGCAGA CCCCAATACC GAGGACTGGA AAATACTGCT CAAGAACCAG 
GCAGCACAGG GACAGTGGGA GGATGTGGTG GTGGTCGGGG AGGAAAACTT CACCACCCCC 
TGCTACATTC AGCTGGATGC AGAGGCCTGC CACATCCTCA CAGAGAACCT CAGCACCTAC 
GCCCTGGTAG GACATTCCAC CACCAAAGCG GCTGCGAAGC GCCTCAAGCT GGCCATCTTT 
GGGCCCCTGT GCTGCTCCTC GCTGGAGTAC AGCATCCGAG TCTACTGTCT GGATGACACC 
CAGGATGCCC TGAAGGAAAT TTTACATCTT GAGAGACAGA TGGGAGGACA GCTCCTAGAA 
GAACCTAAGG CTCTTCATTT TAAAGGCAGC ACCCACAACC TGCGCCTGTC AATTCACGAT 
ATCGCCCATT CCCTCTGGAA GAGCAAATTG CTGGCTAAAT ATCAGGAAAT TCCATTTTAC 
CATGTTTGGA GTGGATCTCA AAGAAACCTG CACTGCACCT TCACTCTGGA AAGATTTAGC 
CTGAACACAG TGGAGCTGGT TTGCAAACTC TGTGTGCGGC AGGTGGAAGG AGAAGGGCAG 
ATCTTCCAGC TCAACTGCAC CGTGTCAGAG GAACCTACTG GCATCGATTT GCCGCTGCTG 
GATCCTGCGA ACACCATCAC CACGGTCACG GGGCCCAGTG CTTTCAGCAT CCCTCTCCCT 
ATCCGGCAGA AGCTCTGTAG CAGCCTGGAT GCCCCCCAGA CGAGAGGCCA TGACTGGAGG 
ATGCTGGCCC ATAAGCTGAA CCTGGACAGG TACTTGAATT ACTTTGCCAC CAAATCCAGC 
CCAACTGGCG TAATCCTGGA TCTTTGGGAA GCACAGAACT TCCCAGATGG AAACCTGAGC 
ATGCTGGCAG CTGTCTTGGA AGAAATGGGA AGACATGAAA CGGTGGTGTC CTTAGCAGCA 
GAAGGGCAGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC5C ( XM_017008790.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864279.1 Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X3, mRNA.

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CloneID	OHu95521
Clone ID Related Accession (Same CDS sequence)	XM_017008789.1 , XM_017008790.1
Accession Version	XM_017008790.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1695bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	netrin receptor UNC5C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGACTG CTCCTGATTC AGATGATGTT GCTCTCTATG TTGGGATTGT GATAGCAGTG 
ATCGTTTGCC TGGCGATCTC TGTAGTTGTG GCCTTGTTTG TGTATCGGAA GAATCATCGT 
GACTTTGAGT CAGATATTAT TGACTCTTCG GCACTCAATG GGGGCTTTCA GCCTGTGAAC 
ATCAAGGCAG CAAGACAAGA TCTGCTGGCT GTACCCCCAG ACCTCACGTC AGCTGCAGCC 
ATGTACAGAG GACCTGTCTA TGCCCTGCAT GACGTCTCAG ACAAAATCCC AATGACCAAC 
TCTCCAATTC TGGATCCACT GCCCAACCTG AAAATCAAAG TGTACAACAC CTCAGGTGCT 
GTCACCCCCC AAGATGACCT CTCTGAGTTT ACGTCCAAGC TGTCCCCTCA GATGACCCAG 
TCGTTGTTGG AGAATGAAGC CCTCAGCCTG AAGAACCAGA GTCTAGCAAG GCAGACTGAT 
CCATCCTGTA CCGCATTTGG CAGCTTCAAC TCGCTGGGAG GTCACCTTAT TGTTCCCAAT 
TCAGGAGTCA GCTTGCTGAT TCCCGCTGGG GCCATTCCCC AAGGGAGAGT CTACGAAATG 
TATGTGACTG TACACAGGAA AGAAACTATG AGGCCACCCA TGGATGACTC TCAGACACTT 
TTGACCCCTG TGGTGAGCTG TGGGCCCCCA GGAGCTCTGC TCACCCGCCC AGTCGTCCTC 
ACTATGCATC ACTGCGCAGA CCCCAATACC GAGGACTGGA AAATACTGCT CAAGAACCAG 
GCAGCACAGG GACAGTGGGA GGATGTGGTG GTGGTCGGGG AGGAAAACTT CACCACCCCC 
TGCTACATTC AGCTGGATGC AGAGGCCTGC CACATCCTCA CAGAGAACCT CAGCACCTAC 
GCCCTGGTAG GACATTCCAC CACCAAAGCG GCTGCGAAGC GCCTCAAGCT GGCCATCTTT 
GGGCCCCTGT GCTGCTCCTC GCTGGAGTAC AGCATCCGAG TCTACTGTCT GGATGACACC 
CAGGATGCCC TGAAGGAAAT TTTACATCTT GAGAGACAGA TGGGAGGACA GCTCCTAGAA 
GAACCTAAGG CTCTTCATTT TAAAGGCAGC ACCCACAACC TGCGCCTGTC AATTCACGAT 
ATCGCCCATT CCCTCTGGAA GAGCAAATTG CTGGCTAAAT ATCAGGAAAT TCCATTTTAC 
CATGTTTGGA GTGGATCTCA AAGAAACCTG CACTGCACCT TCACTCTGGA AAGATTTAGC 
CTGAACACAG TGGAGCTGGT TTGCAAACTC TGTGTGCGGC AGGTGGAAGG AGAAGGGCAG 
ATCTTCCAGC TCAACTGCAC CGTGTCAGAG GAACCTACTG GCATCGATTT GCCGCTGCTG 
GATCCTGCGA ACACCATCAC CACGGTCACG GGGCCCAGTG CTTTCAGCAT CCCTCTCCCT 
ATCCGGCAGA AGCTCTGTAG CAGCCTGGAT GCCCCCCAGA CGAGAGGCCA TGACTGGAGG 
ATGCTGGCCC ATAAGCTGAA CCTGGACAGG TACTTGAATT ACTTTGCCAC CAAATCCAGC 
CCAACTGGCG TAATCCTGGA TCTTTGGGAA GCACAGAACT TCCCAGATGG AAACCTGAGC 
ATGCTGGCAG CTGTCTTGGA AGAAATGGGA AGACATGAAA CGGTGGTGTC CTTAGCAGCA 
GAAGGGCAGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864279.1
CDS	1100..2794
Translation	MQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

Target ORF information:

RefSeq Version	XM_017008790.1
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-5 netrin receptor C (UNC5C), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008790.1

ORF Insert Sequence:

ATGCAGACTG CTCCTGATTC AGATGATGTT GCTCTCTATG TTGGGATTGT GATAGCAGTG 
ATCGTTTGCC TGGCGATCTC TGTAGTTGTG GCCTTGTTTG TGTATCGGAA GAATCATCGT 
GACTTTGAGT CAGATATTAT TGACTCTTCG GCACTCAATG GGGGCTTTCA GCCTGTGAAC 
ATCAAGGCAG CAAGACAAGA TCTGCTGGCT GTACCCCCAG ACCTCACGTC AGCTGCAGCC 
ATGTACAGAG GACCTGTCTA TGCCCTGCAT GACGTCTCAG ACAAAATCCC AATGACCAAC 
TCTCCAATTC TGGATCCACT GCCCAACCTG AAAATCAAAG TGTACAACAC CTCAGGTGCT 
GTCACCCCCC AAGATGACCT CTCTGAGTTT ACGTCCAAGC TGTCCCCTCA GATGACCCAG 
TCGTTGTTGG AGAATGAAGC CCTCAGCCTG AAGAACCAGA GTCTAGCAAG GCAGACTGAT 
CCATCCTGTA CCGCATTTGG CAGCTTCAAC TCGCTGGGAG GTCACCTTAT TGTTCCCAAT 
TCAGGAGTCA GCTTGCTGAT TCCCGCTGGG GCCATTCCCC AAGGGAGAGT CTACGAAATG 
TATGTGACTG TACACAGGAA AGAAACTATG AGGCCACCCA TGGATGACTC TCAGACACTT 
TTGACCCCTG TGGTGAGCTG TGGGCCCCCA GGAGCTCTGC TCACCCGCCC AGTCGTCCTC 
ACTATGCATC ACTGCGCAGA CCCCAATACC GAGGACTGGA AAATACTGCT CAAGAACCAG 
GCAGCACAGG GACAGTGGGA GGATGTGGTG GTGGTCGGGG AGGAAAACTT CACCACCCCC 
TGCTACATTC AGCTGGATGC AGAGGCCTGC CACATCCTCA CAGAGAACCT CAGCACCTAC 
GCCCTGGTAG GACATTCCAC CACCAAAGCG GCTGCGAAGC GCCTCAAGCT GGCCATCTTT 
GGGCCCCTGT GCTGCTCCTC GCTGGAGTAC AGCATCCGAG TCTACTGTCT GGATGACACC 
CAGGATGCCC TGAAGGAAAT TTTACATCTT GAGAGACAGA TGGGAGGACA GCTCCTAGAA 
GAACCTAAGG CTCTTCATTT TAAAGGCAGC ACCCACAACC TGCGCCTGTC AATTCACGAT 
ATCGCCCATT CCCTCTGGAA GAGCAAATTG CTGGCTAAAT ATCAGGAAAT TCCATTTTAC 
CATGTTTGGA GTGGATCTCA AAGAAACCTG CACTGCACCT TCACTCTGGA AAGATTTAGC 
CTGAACACAG TGGAGCTGGT TTGCAAACTC TGTGTGCGGC AGGTGGAAGG AGAAGGGCAG 
ATCTTCCAGC TCAACTGCAC CGTGTCAGAG GAACCTACTG GCATCGATTT GCCGCTGCTG 
GATCCTGCGA ACACCATCAC CACGGTCACG GGGCCCAGTG CTTTCAGCAT CCCTCTCCCT 
ATCCGGCAGA AGCTCTGTAG CAGCCTGGAT GCCCCCCAGA CGAGAGGCCA TGACTGGAGG 
ATGCTGGCCC ATAAGCTGAA CCTGGACAGG TACTTGAATT ACTTTGCCAC CAAATCCAGC 
CCAACTGGCG TAATCCTGGA TCTTTGGGAA GCACAGAACT TCCCAGATGG AAACCTGAGC 
ATGCTGGCAG CTGTCTTGGA AGAAATGGGA AGACATGAAA CGGTGGTGTC CTTAGCAGCA 
GAAGGGCAGT ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(23)5620-5633(2017 Jun)
Shao Q,Yang T,Huang H,Alarmanazi F,Liu G

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
PLoS medicine14(4)e1002287(2017 Apr)
White CC,Yang HS,Yu L,Chibnik LB,Dawe RJ,Yang J,Klein HU,Felsky D,Ramos-Miguel A,Arfanakis K,Honer WG,Sperling RA,Schneider JA,Bennett DA,De Jager PL

Methylation of the UNC5C gene and its protein expression in colorectal cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(4)1010428317697564(2017 Apr)
Wu J,Wang G,He B,Chen X,An Y

An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid ? Precursor Protein Signaling.
The Journal of biological chemistry291(23)12282-93(2016 Jun)
Hashimoto Y,Toyama Y,Kusakari S,Nawa M,Matsuoka M

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UNC5C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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