SLITRK6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLITRK6
Entrez Gene ID	84189
Full Name	SLIT and NTRK like family member 6
Synonyms	DFNMYP
General protein information	Preferred Names SLIT and NTRK like family member 6 Names SLIT and NTRK-like protein 6 4832410J21Rik slit and trk like gene 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q31.1
Summary	This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014].
Disorder MIM:	609681
Disorder Html:	Deafness and myopia, 221200 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_032229.2	NP_115605.2	SLIT and NTRK-like protein 6 precursor
NM_032229.3	NP_115605.2	SLIT and NTRK-like protein 6 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLITRK6	NP_115605.2
Pan troglodytes (chimpanzee)	SLITRK6	XP_522691.2
	SLITRK6	XP_001093456.1
Canis lupus familiaris (dog)	SLITRK6	XP_005634068.1
Rattus norvegicus (Norway rat)	Slitrk6	NP_001099527.1
Gallus gallus (chicken)	SLITRK6	XP_003640598.1
Bos taurus (cattle)	SLITRK6	XP_005213943.1
Mus musculus (house mouse)	Slitrk6	NP_780708.1
Danio rerio (zebrafish)	slitrk6	XP_003197659.1
Xenopus tropicalis (tropical clawed frog)	slitrk6	XP_004911884.1

Gene Ontology
Bibliography

Related articles in PubMed

Human cytomegalovirus downregulates SLITRK6 expression through IE2.
Liao H, Sato H, Chiba R, Kawai T, Nakabayashi K, Hata K, Akutsu H, Fujiwara S, Nakamura H
Journal of neurovirology23(1)79-86(2017 Feb)

A homozygous SLITRK6 nonsense mutation is associated with progressive auditory neuropathy in humans.
Morlet T, Rabinowitz MR, Looney LR, Riegner T, Greenwood LA, Sherman EA, Achilly N, Zhu A, Yoo E, O'Reilly RC, Jinks RN, Puffenberger EG, Heaps A, Morton H, Strauss KA
The Laryngoscope124(3)E95-103(2014 Mar)

SLITRK6 mutations cause myopia and deafness in humans and mice.
Tekin M, Chioza BA, Matsumoto Y, Diaz-Horta O, Cross HE, Duman D, Kokotas H, Moore-Barton HL, Sakoori K, Ota M, Odaka YS, Foster J 2nd, Cengiz FB, Tokgoz-Yilmaz S, Tekeli O, Grigoriadou M, Petersen MB, Sreekantan-Nair A, Gurtz K, Xia XJ, Pandya A, Patton MA, Young JI, Aruga J, Crosby AH
The Journal of clinical investigation123(5)2094-102(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans.
Title: A homozygous SLITRK6 nonsense mutation is associated with progressive auditory neuropathy in humans.

SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness.
Title: SLITRK6 mutations cause myopia and deafness in humans and mice.

The following SLITRK6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLITRK6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20098	NM_032229.3 Latest version!	Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu20098	NM_032229.2	Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLITRK6 ( NM_032229.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_115605.2 Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.

Price & Availability↑

CloneID	OHu20098
Clone ID Related Accession (Same CDS sequence)	NM_032229.2 , NM_032229.3
Accession Version	NM_032229.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	SLIT and NTRK-like protein 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD687435.1, BX648640.1, AK026427.1 and BQ772084.1. This sequence is a reference standard in the RefSeqGene project. On Dec 19, 2003 this sequence version replaced NM_032229.1. ##Evidence-Data-START## Transcript exon combination :: DB232992.1, SRR1803611.110169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGT GGATTCATCT CTTTTATTCA TCTCTCCTTG CCTGTATATC TTTACACTCC 
CAAACTCCAG TGCTCTCATC CAGAGGCTCT TGTGATTCTC TTTGCAATTG TGAGGAAAAA 
GATGGCACAA TGCTAATAAA TTGTGAAGCA AAAGGTATCA AGATGGTATC TGAAATAAGT 
GTGCCACCAT CACGACCTTT CCAACTAAGC TTATTAAATA ACGGCTTGAC GATGCTTCAC 
ACAAATGACT TTTCTGGGCT TACCAATGCT ATTTCAATAC ACCTTGGATT TAACAATATT 
GCAGATATTG AGATAGGTGC ATTTAATGGC CTTGGCCTCC TGAAACAACT TCATATCAAT 
CACAATTCTT TAGAAATTCT TAAAGAGGAT ACTTTCCATG GACTGGAAAA CCTGGAATTC 
CTGCAAGCAG ATAACAATTT TATCACAGTG ATTGAACCAA GTGCCTTTAG CAAGCTCAAC 
AGACTCAAAG TGTTAATTTT AAATGACAAT GCTATTGAGA GTCTTCCTCC AAACATCTTC 
CGATTTGTTC CTTTAACCCA TCTAGATCTT CGTGGAAATC AATTACAAAC ATTGCCTTAT 
GTTGGTTTTC TCGAACACAT TGGCCGAATA TTGGATCTTC AGTTGGAGGA CAACAAATGG 
GCCTGCAATT GTGACTTATT GCAGTTAAAA ACTTGGTTGG AGAACATGCC TCCACAGTCT 
ATAATTGGTG ATGTTGTCTG CAACAGCCCT CCATTTTTTA AAGGAAGTAT ACTCAGTAGA 
CTAAAGAAGG AATCTATTTG CCCTACTCCA CCAGTGTATG AAGAACATGA GGATCCTTCA 
GGATCATTAC ATCTGGCAGC AACATCTTCA ATAAATGATA GTCGCATGTC AACTAAGACC 
ACGTCCATTC TAAAACTACC CACCAAAGCA CCAGGTTTGA TACCTTATAT TACAAAGCCA 
TCCACTCAAC TTCCAGGACC TTACTGCCCT ATTCCTTGTA ACTGCAAAGT CCTATCCCCA 
TCAGGACTTC TAATACATTG TCAGGAGCGC AACATTGAAA GCTTATCAGA TCTGAGACCT 
CCTCCGCAAA ATCCTAGAAA GCTCATTCTA GCGGGAAATA TTATTCACAG TTTAATGAAG 
TCTGATCTAG TGGAATATTT CACTTTGGAA ATGCTTCACT TGGGAAACAA TCGTATTGAA 
GTTCTTGAAG AAGGATCGTT TATGAACCTA ACGAGATTAC AAAAACTCTA TCTAAATGGT 
AACCACCTGA CCAAATTAAG TAAAGGCATG TTCCTTGGTC TCCATAATCT TGAATACTTA 
TATCTTGAAT ACAATGCCAT TAAGGAAATA CTGCCAGGAA CCTTTAATCC AATGCCTAAA 
CTTAAAGTCC TGTATTTAAA TAACAACCTC CTCCAAGTTT TACCACCACA TATTTTTTCA 
GGGGTTCCTC TAACTAAGGT AAATCTTAAA ACAAACCAGT TTACCCATCT ACCTGTAAGT 
AATATTTTGG ATGATCTTGA TTTGCTAACC CAGATTGACC TTGAGGATAA CCCCTGGGAC 
TGCTCCTGTG ACCTGGTTGG ACTGCAGCAA TGGATACAAA AGTTAAGCAA GAACACAGTG 
ACAGATGACA TCCTCTGCAC TTCCCCCGGG CATCTCGACA AAAAGGAATT GAAAGCCCTA 
AATAGTGAAA TTCTCTGTCC AGGTTTAGTA AATAACCCAT CCATGCCAAC ACAGACTAGT 
TACCTTATGG TCACCACTCC TGCAACAACA ACAAATACGG CTGATACTAT TTTACGATCT 
CTTACGGACG CTGTGCCACT GTCTGTTCTA ATATTGGGAC TTCTGATTAT GTTCATCACT 
ATTGTTTTCT GTGCTGCAGG GATAGTGGTT CTTGTTCTTC ACCGCAGGAG AAGATACAAA 
AAGAAACAAG TAGATGAGCA AATGAGAGAC AACAGTCCTG TGCATCTTCA GTACAGCATG 
TATGGCCATA AAACCACTCA TCACACTACT GAAAGACCCT CTGCCTCACT CTATGAACAG 
CACATGGTGA GCCCCATGGT TCATGTCTAT AGAAGTCCAT CCTTTGGTCC AAAGCATCTG 
GAAGAGGAAG AAGAGAGGAA TGAGAAAGAA GGAAGTGATG CAAAACATCT CCAAAGAAGT 
CTTTTGGAAC AGGAAAATCA TTCACCACTC ACAGGGTCAA ATATGAAATA CAAAACCACG 
AACCAATCAA CAGAATTTTT ATCCTTCCAA GATGCCAGCT CATTGTACAG AAACATTTTA 
GAAAAAGAAA GGGAACTTCA GCAACTGGGA ATCACAGAAT ACCTAAGGAA AAACATTGCT 
CAGCTCCAGC CTGATATGGA GGCACATTAT CCTGGAGCCC ACGAAGAGCT GAAGTTAATG 
GAAACATTAA TGTACTCACG TCCAAGGAAG GTATTAGTGG AACAGACAAA AAATGAGTAT 
TTTGAACTTA AAGCTAATTT ACATGCTGAA CCTGACTATT TAGAAGTCCT GGAGCAGCAA 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115605.2
CDS	460..2985
Translation	MKLWIHLFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRLKKESICPTPPVYEEHEDPSGSLHLAATSSINDSRMSTKTTSILKLPTKAPGLIPYITKPSTQLPGPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLMVTTPATTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRRYKKKQVDEQMRDNSPVHLQYSMYGHKTTHHTTERPSASLYEQHMVSPMVHVYRSPSFGPKHLEEEEERNEKEGSDAKHLQRSLLEQENHSPLTGSNMKYKTTNQSTEFLSFQDASSLYRNILEKERELQQLGITEYLRKNIAQLQPDMEAHYPGAHEELKLMETLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT

Target ORF information:

RefSeq Version	NM_032229.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032229.2

ORF Insert Sequence:

ATGAAGCTGT GGATTCATCT CTTTTATTCA TCTCTCCTTG CCTGTATATC TTTACACTCC 
CAAACTCCAG TGCTCTCATC CAGAGGCTCT TGTGATTCTC TTTGCAATTG TGAGGAAAAA 
GATGGCACAA TGCTAATAAA TTGTGAAGCA AAAGGTATCA AGATGGTATC TGAAATAAGT 
GTGCCACCAT CACGACCTTT CCAACTAAGC TTATTAAATA ACGGCTTGAC GATGCTTCAC 
ACAAATGACT TTTCTGGGCT TACCAATGCT ATTTCAATAC ACCTTGGATT TAACAATATT 
GCAGATATTG AGATAGGTGC ATTTAATGGC CTTGGCCTCC TGAAACAACT TCATATCAAT 
CACAATTCTT TAGAAATTCT TAAAGAGGAT ACTTTCCATG GACTGGAAAA CCTGGAATTC 
CTGCAAGCAG ATAACAATTT TATCACAGTG ATTGAACCAA GTGCCTTTAG CAAGCTCAAC 
AGACTCAAAG TGTTAATTTT AAATGACAAT GCTATTGAGA GTCTTCCTCC AAACATCTTC 
CGATTTGTTC CTTTAACCCA TCTAGATCTT CGTGGAAATC AATTACAAAC ATTGCCTTAT 
GTTGGTTTTC TCGAACACAT TGGCCGAATA TTGGATCTTC AGTTGGAGGA CAACAAATGG 
GCCTGCAATT GTGACTTATT GCAGTTAAAA ACTTGGTTGG AGAACATGCC TCCACAGTCT 
ATAATTGGTG ATGTTGTCTG CAACAGCCCT CCATTTTTTA AAGGAAGTAT ACTCAGTAGA 
CTAAAGAAGG AATCTATTTG CCCTACTCCA CCAGTGTATG AAGAACATGA GGATCCTTCA 
GGATCATTAC ATCTGGCAGC AACATCTTCA ATAAATGATA GTCGCATGTC AACTAAGACC 
ACGTCCATTC TAAAACTACC CACCAAAGCA CCAGGTTTGA TACCTTATAT TACAAAGCCA 
TCCACTCAAC TTCCAGGACC TTACTGCCCT ATTCCTTGTA ACTGCAAAGT CCTATCCCCA 
TCAGGACTTC TAATACATTG TCAGGAGCGC AACATTGAAA GCTTATCAGA TCTGAGACCT 
CCTCCGCAAA ATCCTAGAAA GCTCATTCTA GCGGGAAATA TTATTCACAG TTTAATGAAG 
TCTGATCTAG TGGAATATTT CACTTTGGAA ATGCTTCACT TGGGAAACAA TCGTATTGAA 
GTTCTTGAAG AAGGATCGTT TATGAACCTA ACGAGATTAC AAAAACTCTA TCTAAATGGT 
AACCACCTGA CCAAATTAAG TAAAGGCATG TTCCTTGGTC TCCATAATCT TGAATACTTA 
TATCTTGAAT ACAATGCCAT TAAGGAAATA CTGCCAGGAA CCTTTAATCC AATGCCTAAA 
CTTAAAGTCC TGTATTTAAA TAACAACCTC CTCCAAGTTT TACCACCACA TATTTTTTCA 
GGGGTTCCTC TAACTAAGGT AAATCTTAAA ACAAACCAGT TTACCCATCT ACCTGTAAGT 
AATATTTTGG ATGATCTTGA TTTGCTAACC CAGATTGACC TTGAGGATAA CCCCTGGGAC 
TGCTCCTGTG ACCTGGTTGG ACTGCAGCAA TGGATACAAA AGTTAAGCAA GAACACAGTG 
ACAGATGACA TCCTCTGCAC TTCCCCCGGG CATCTCGACA AAAAGGAATT GAAAGCCCTA 
AATAGTGAAA TTCTCTGTCC AGGTTTAGTA AATAACCCAT CCATGCCAAC ACAGACTAGT 
TACCTTATGG TCACCACTCC TGCAACAACA ACAAATACGG CTGATACTAT TTTACGATCT 
CTTACGGACG CTGTGCCACT GTCTGTTCTA ATATTGGGAC TTCTGATTAT GTTCATCACT 
ATTGTTTTCT GTGCTGCAGG GATAGTGGTT CTTGTTCTTC ACCGCAGGAG AAGATACAAA 
AAGAAACAAG TAGATGAGCA AATGAGAGAC AACAGTCCTG TGCATCTTCA GTACAGCATG 
TATGGCCATA AAACCACTCA TCACACTACT GAAAGACCCT CTGCCTCACT CTATGAACAG 
CACATGGTGA GCCCCATGGT TCATGTCTAT AGAAGTCCAT CCTTTGGTCC AAAGCATCTG 
GAAGAGGAAG AAGAGAGGAA TGAGAAAGAA GGAAGTGATG CAAAACATCT CCAAAGAAGT 
CTTTTGGAAC AGGAAAATCA TTCACCACTC ACAGGGTCAA ATATGAAATA CAAAACCACG 
AACCAATCAA CAGAATTTTT ATCCTTCCAA GATGCCAGCT CATTGTACAG AAACATTTTA 
GAAAAAGAAA GGGAACTTCA GCAACTGGGA ATCACAGAAT ACCTAAGGAA AAACATTGCT 
CAGCTCCAGC CTGATATGGA GGCACATTAT CCTGGAGCCC ACGAAGAGCT GAAGTTAATG 
GAAACATTAA TGTACTCACG TCCAAGGAAG GTATTAGTGG AACAGACAAA AAATGAGTAT 
TTTGAACTTA AAGCTAATTT ACATGCTGAA CCTGACTATT TAGAAGTCCT GGAGCAGCAA 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLITRK6 ( NM_032229.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115605.2 Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.

Price & Availability↑

CloneID	OHu20098
Clone ID Related Accession (Same CDS sequence)	NM_032229.2 , NM_032229.3
Accession Version	NM_032229.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	SLIT and NTRK-like protein 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL162373.16. This sequence is a reference standard in the RefSeqGene project. On Nov 25, 2018 this sequence version replaced NM_032229.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.110169.1, SRR1803615.217780.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000647374.2/ ENSP00000495507.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCTGT GGATTCATCT CTTTTATTCA TCTCTCCTTG CCTGTATATC TTTACACTCC 
CAAACTCCAG TGCTCTCATC CAGAGGCTCT TGTGATTCTC TTTGCAATTG TGAGGAAAAA 
GATGGCACAA TGCTAATAAA TTGTGAAGCA AAAGGTATCA AGATGGTATC TGAAATAAGT 
GTGCCACCAT CACGACCTTT CCAACTAAGC TTATTAAATA ACGGCTTGAC GATGCTTCAC 
ACAAATGACT TTTCTGGGCT TACCAATGCT ATTTCAATAC ACCTTGGATT TAACAATATT 
GCAGATATTG AGATAGGTGC ATTTAATGGC CTTGGCCTCC TGAAACAACT TCATATCAAT 
CACAATTCTT TAGAAATTCT TAAAGAGGAT ACTTTCCATG GACTGGAAAA CCTGGAATTC 
CTGCAAGCAG ATAACAATTT TATCACAGTG ATTGAACCAA GTGCCTTTAG CAAGCTCAAC 
AGACTCAAAG TGTTAATTTT AAATGACAAT GCTATTGAGA GTCTTCCTCC AAACATCTTC 
CGATTTGTTC CTTTAACCCA TCTAGATCTT CGTGGAAATC AATTACAAAC ATTGCCTTAT 
GTTGGTTTTC TCGAACACAT TGGCCGAATA TTGGATCTTC AGTTGGAGGA CAACAAATGG 
GCCTGCAATT GTGACTTATT GCAGTTAAAA ACTTGGTTGG AGAACATGCC TCCACAGTCT 
ATAATTGGTG ATGTTGTCTG CAACAGCCCT CCATTTTTTA AAGGAAGTAT ACTCAGTAGA 
CTAAAGAAGG AATCTATTTG CCCTACTCCA CCAGTGTATG AAGAACATGA GGATCCTTCA 
GGATCATTAC ATCTGGCAGC AACATCTTCA ATAAATGATA GTCGCATGTC AACTAAGACC 
ACGTCCATTC TAAAACTACC CACCAAAGCA CCAGGTTTGA TACCTTATAT TACAAAGCCA 
TCCACTCAAC TTCCAGGACC TTACTGCCCT ATTCCTTGTA ACTGCAAAGT CCTATCCCCA 
TCAGGACTTC TAATACATTG TCAGGAGCGC AACATTGAAA GCTTATCAGA TCTGAGACCT 
CCTCCGCAAA ATCCTAGAAA GCTCATTCTA GCGGGAAATA TTATTCACAG TTTAATGAAG 
TCTGATCTAG TGGAATATTT CACTTTGGAA ATGCTTCACT TGGGAAACAA TCGTATTGAA 
GTTCTTGAAG AAGGATCGTT TATGAACCTA ACGAGATTAC AAAAACTCTA TCTAAATGGT 
AACCACCTGA CCAAATTAAG TAAAGGCATG TTCCTTGGTC TCCATAATCT TGAATACTTA 
TATCTTGAAT ACAATGCCAT TAAGGAAATA CTGCCAGGAA CCTTTAATCC AATGCCTAAA 
CTTAAAGTCC TGTATTTAAA TAACAACCTC CTCCAAGTTT TACCACCACA TATTTTTTCA 
GGGGTTCCTC TAACTAAGGT AAATCTTAAA ACAAACCAGT TTACCCATCT ACCTGTAAGT 
AATATTTTGG ATGATCTTGA TTTGCTAACC CAGATTGACC TTGAGGATAA CCCCTGGGAC 
TGCTCCTGTG ACCTGGTTGG ACTGCAGCAA TGGATACAAA AGTTAAGCAA GAACACAGTG 
ACAGATGACA TCCTCTGCAC TTCCCCCGGG CATCTCGACA AAAAGGAATT GAAAGCCCTA 
AATAGTGAAA TTCTCTGTCC AGGTTTAGTA AATAACCCAT CCATGCCAAC ACAGACTAGT 
TACCTTATGG TCACCACTCC TGCAACAACA ACAAATACGG CTGATACTAT TTTACGATCT 
CTTACGGACG CTGTGCCACT GTCTGTTCTA ATATTGGGAC TTCTGATTAT GTTCATCACT 
ATTGTTTTCT GTGCTGCAGG GATAGTGGTT CTTGTTCTTC ACCGCAGGAG AAGATACAAA 
AAGAAACAAG TAGATGAGCA AATGAGAGAC AACAGTCCTG TGCATCTTCA GTACAGCATG 
TATGGCCATA AAACCACTCA TCACACTACT GAAAGACCCT CTGCCTCACT CTATGAACAG 
CACATGGTGA GCCCCATGGT TCATGTCTAT AGAAGTCCAT CCTTTGGTCC AAAGCATCTG 
GAAGAGGAAG AAGAGAGGAA TGAGAAAGAA GGAAGTGATG CAAAACATCT CCAAAGAAGT 
CTTTTGGAAC AGGAAAATCA TTCACCACTC ACAGGGTCAA ATATGAAATA CAAAACCACG 
AACCAATCAA CAGAATTTTT ATCCTTCCAA GATGCCAGCT CATTGTACAG AAACATTTTA 
GAAAAAGAAA GGGAACTTCA GCAACTGGGA ATCACAGAAT ACCTAAGGAA AAACATTGCT 
CAGCTCCAGC CTGATATGGA GGCACATTAT CCTGGAGCCC ACGAAGAGCT GAAGTTAATG 
GAAACATTAA TGTACTCACG TCCAAGGAAG GTATTAGTGG AACAGACAAA AAATGAGTAT 
TTTGAACTTA AAGCTAATTT ACATGCTGAA CCTGACTATT TAGAAGTCCT GGAGCAGCAA 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115605.2
CDS	531..3056
Translation	MKLWIHLFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRLKKESICPTPPVYEEHEDPSGSLHLAATSSINDSRMSTKTTSILKLPTKAPGLIPYITKPSTQLPGPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLMVTTPATTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRRYKKKQVDEQMRDNSPVHLQYSMYGHKTTHHTTERPSASLYEQHMVSPMVHVYRSPSFGPKHLEEEEERNEKEGSDAKHLQRSLLEQENHSPLTGSNMKYKTTNQSTEFLSFQDASSLYRNILEKERELQQLGITEYLRKNIAQLQPDMEAHYPGAHEELKLMETLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT

Target ORF information:

RefSeq Version	NM_032229.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SLIT and NTRK like family member 6 (SLITRK6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032229.3

ORF Insert Sequence:

ATGAAGCTGT GGATTCATCT CTTTTATTCA TCTCTCCTTG CCTGTATATC TTTACACTCC 
CAAACTCCAG TGCTCTCATC CAGAGGCTCT TGTGATTCTC TTTGCAATTG TGAGGAAAAA 
GATGGCACAA TGCTAATAAA TTGTGAAGCA AAAGGTATCA AGATGGTATC TGAAATAAGT 
GTGCCACCAT CACGACCTTT CCAACTAAGC TTATTAAATA ACGGCTTGAC GATGCTTCAC 
ACAAATGACT TTTCTGGGCT TACCAATGCT ATTTCAATAC ACCTTGGATT TAACAATATT 
GCAGATATTG AGATAGGTGC ATTTAATGGC CTTGGCCTCC TGAAACAACT TCATATCAAT 
CACAATTCTT TAGAAATTCT TAAAGAGGAT ACTTTCCATG GACTGGAAAA CCTGGAATTC 
CTGCAAGCAG ATAACAATTT TATCACAGTG ATTGAACCAA GTGCCTTTAG CAAGCTCAAC 
AGACTCAAAG TGTTAATTTT AAATGACAAT GCTATTGAGA GTCTTCCTCC AAACATCTTC 
CGATTTGTTC CTTTAACCCA TCTAGATCTT CGTGGAAATC AATTACAAAC ATTGCCTTAT 
GTTGGTTTTC TCGAACACAT TGGCCGAATA TTGGATCTTC AGTTGGAGGA CAACAAATGG 
GCCTGCAATT GTGACTTATT GCAGTTAAAA ACTTGGTTGG AGAACATGCC TCCACAGTCT 
ATAATTGGTG ATGTTGTCTG CAACAGCCCT CCATTTTTTA AAGGAAGTAT ACTCAGTAGA 
CTAAAGAAGG AATCTATTTG CCCTACTCCA CCAGTGTATG AAGAACATGA GGATCCTTCA 
GGATCATTAC ATCTGGCAGC AACATCTTCA ATAAATGATA GTCGCATGTC AACTAAGACC 
ACGTCCATTC TAAAACTACC CACCAAAGCA CCAGGTTTGA TACCTTATAT TACAAAGCCA 
TCCACTCAAC TTCCAGGACC TTACTGCCCT ATTCCTTGTA ACTGCAAAGT CCTATCCCCA 
TCAGGACTTC TAATACATTG TCAGGAGCGC AACATTGAAA GCTTATCAGA TCTGAGACCT 
CCTCCGCAAA ATCCTAGAAA GCTCATTCTA GCGGGAAATA TTATTCACAG TTTAATGAAG 
TCTGATCTAG TGGAATATTT CACTTTGGAA ATGCTTCACT TGGGAAACAA TCGTATTGAA 
GTTCTTGAAG AAGGATCGTT TATGAACCTA ACGAGATTAC AAAAACTCTA TCTAAATGGT 
AACCACCTGA CCAAATTAAG TAAAGGCATG TTCCTTGGTC TCCATAATCT TGAATACTTA 
TATCTTGAAT ACAATGCCAT TAAGGAAATA CTGCCAGGAA CCTTTAATCC AATGCCTAAA 
CTTAAAGTCC TGTATTTAAA TAACAACCTC CTCCAAGTTT TACCACCACA TATTTTTTCA 
GGGGTTCCTC TAACTAAGGT AAATCTTAAA ACAAACCAGT TTACCCATCT ACCTGTAAGT 
AATATTTTGG ATGATCTTGA TTTGCTAACC CAGATTGACC TTGAGGATAA CCCCTGGGAC 
TGCTCCTGTG ACCTGGTTGG ACTGCAGCAA TGGATACAAA AGTTAAGCAA GAACACAGTG 
ACAGATGACA TCCTCTGCAC TTCCCCCGGG CATCTCGACA AAAAGGAATT GAAAGCCCTA 
AATAGTGAAA TTCTCTGTCC AGGTTTAGTA AATAACCCAT CCATGCCAAC ACAGACTAGT 
TACCTTATGG TCACCACTCC TGCAACAACA ACAAATACGG CTGATACTAT TTTACGATCT 
CTTACGGACG CTGTGCCACT GTCTGTTCTA ATATTGGGAC TTCTGATTAT GTTCATCACT 
ATTGTTTTCT GTGCTGCAGG GATAGTGGTT CTTGTTCTTC ACCGCAGGAG AAGATACAAA 
AAGAAACAAG TAGATGAGCA AATGAGAGAC AACAGTCCTG TGCATCTTCA GTACAGCATG 
TATGGCCATA AAACCACTCA TCACACTACT GAAAGACCCT CTGCCTCACT CTATGAACAG 
CACATGGTGA GCCCCATGGT TCATGTCTAT AGAAGTCCAT CCTTTGGTCC AAAGCATCTG 
GAAGAGGAAG AAGAGAGGAA TGAGAAAGAA GGAAGTGATG CAAAACATCT CCAAAGAAGT 
CTTTTGGAAC AGGAAAATCA TTCACCACTC ACAGGGTCAA ATATGAAATA CAAAACCACG 
AACCAATCAA CAGAATTTTT ATCCTTCCAA GATGCCAGCT CATTGTACAG AAACATTTTA 
GAAAAAGAAA GGGAACTTCA GCAACTGGGA ATCACAGAAT ACCTAAGGAA AAACATTGCT 
CAGCTCCAGC CTGATATGGA GGCACATTAT CCTGGAGCCC ACGAAGAGCT GAAGTTAATG 
GAAACATTAA TGTACTCACG TCCAAGGAAG GTATTAGTGG AACAGACAAA AAATGAGTAT 
TTTGAACTTA AAGCTAATTT ACATGCTGAA CCTGACTATT TAGAAGTCCT GGAGCAGCAA 
ACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human cytomegalovirus downregulates SLITRK6 expression through IE2.
Journal of neurovirology23(1)79-86(2017 Feb)
Liao H,Sato H,Chiba R,Kawai T,Nakabayashi K,Hata K,Akutsu H,Fujiwara S,Nakamura H

A homozygous SLITRK6 nonsense mutation is associated with progressive auditory neuropathy in humans.
The Laryngoscope124(3)E95-103(2014 Mar)
Morlet T,Rabinowitz MR,Looney LR,Riegner T,Greenwood LA,Sherman EA,Achilly N,Zhu A,Yoo E,O'Reilly RC,Jinks RN,Puffenberger EG,Heaps A,Morton H,Strauss KA

SLITRK6 mutations cause myopia and deafness in humans and mice.
The Journal of clinical investigation123(5)2094-102(2013 May)
Tekin M,Chioza BA,Matsumoto Y,Diaz-Horta O,Cross HE,Duman D,Kokotas H,Moore-Barton HL,Sakoori K,Ota M,Odaka YS,Foster J 2nd,Cengiz FB,Tokgoz-Yilmaz S,Tekeli O,Grigoriadou M,Petersen MB,Sreekantan-Nair A,Gurtz K,Xia XJ,Pandya A,Patton MA,Young JI,Aruga J,Crosby AH

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SLITRK6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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