Gene Symbol | RNASEH2B |
Entrez Gene ID | 79621 |
Full Name | ribonuclease H2 subunit B |
Synonyms | AGS2,DLEU8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]. |
Disorder MIM: | |
Disorder Html: | Aicardi-Goutieres syndrome 2, 610181 (3) |