Gene Symbol | CARD14 |
Entrez Gene ID | 79092 |
Full Name | caspase recruitment domain family member 14 |
Synonyms | BIMP2,CARMA2,PRP,PSORS2,PSS1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]. |
Disorder MIM: | |
Disorder Html: | Psoriasis 2, 602723 (3); Pityriasis rubra pilaris, 173200 (3) |