TYMS cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TYMS
Entrez Gene ID	7298
Full Name	thymidylate synthetase
Synonyms	HST422,TMS,TS
General protein information	Preferred Names thymidylate synthetase Names thymidylate synthase TSase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18p11.32
Summary	Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017].
Disorder MIM:	188350

mRNA and Protein(s)

mRNA	Protein	Name
NM_001354867.1	NP_001341796.1	thymidylate synthase isoform 2
NM_001354868.2	NP_001341797.1	thymidylate synthase isoform 3
NM_001354868.1	NP_001341797.1	thymidylate synthase isoform 3
NM_001354867.2	NP_001341796.1	thymidylate synthase isoform 2
XM_024451242.1	XP_024307010.1	thymidylate synthase isoform X1
NM_001071.2	NP_001062.1	thymidylate synthase
NM_001071.4	NP_001062.1	thymidylate synthase isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TYMS	NP_001062.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010457	XP_311491.3
Arabidopsis thaliana (thale cress)	AT2G21550	NP_179750.1
Canis lupus familiaris (dog)	TYMS	NP_001239103.1
Saccharomyces cerevisiae (baker's yeast)	CDC21	NP_014717.2
Eremothecium gossypii	AGOS_ADR219C	NP_984315.1
Magnaporthe oryzae (rice blast fungus)	MGG_04458	XP_003713554.1
Arabidopsis thaliana (thale cress)	THY-2	NP_195183.2
Xenopus tropicalis (tropical clawed frog)	tyms	NP_001072852.1
Rattus norvegicus (Norway rat)	Tyms	NP_062052.1
Gallus gallus (chicken)	TYMS	XP_419147.3
Drosophila melanogaster (fruit fly)	Ts	NP_477367.1
Schizosaccharomyces pombe (fission yeast)	SPAC15E1.04	NP_594305.1
Mus musculus (house mouse)	Tyms	NP_067263.1
Caenorhabditis elegans (roundworm)	Y110A7A.4	NP_491532.3
Neurospora crassa	NCU10053	XP_957941.1
Pan troglodytes (chimpanzee)	TYMS	NP_001233511.1
	TYMS	XP_001089274.1
Bos taurus (cattle)	TYMS	NP_001032905.1
Danio rerio (zebrafish)	tyms	NP_571835.1
Kluyveromyces lactis	KLLA0A07843g	XP_451349.1
Arabidopsis thaliana (thale cress)	THY-1	NP_179230.1

Gene Ontology
Bibliography

Related articles in PubMed

Associative role of TYMS6bpdel polymorphism and resulting hyperhomocysteinemia in the pathogenesis of preterm delivery and associated complications: A study from Northeast India.
Tiwari D, Das CR, Bose PD, Bose S
Gene627129-136(2017 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The study provides crucial information regarding the importance of TYMS6bpdel/del genotype and associated hyperhomocysteinemia in susceptibility to preterm delivery, fetal death and low birth weight.
Title: Associative role of TYMS6bpdel polymorphism and resulting hyperhomocysteinemia in the pathogenesis of preterm delivery and associated complications: A study from Northeast India.

Combined expression analyses of hENT1, TS, and DPD may predict long-term outcomes in patients with borderline resectable pancreatic cancer after neoadjuvant chemoradiotherapy
Title: Combined Analyses of hENT1, TS, and DPD Predict Outcomes of Borderline-resectable Pancreatic Cancer.

High thymidylate synthetase expression is associated with chemoresistance in glioblastoma multiforme.
Title: MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression.

This study finds that measurement of tumor levels of thymidylate synthase is not helpful in assigning specific adjuvant treatment for colorectal cancer. It also highlights the importance of using prospective analyses within treatment clinical trials as the optimal method of determining biomarker utility.
Title: A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803.

The expressions of TYMS, TUBB3 and STMN1 were significantly associated with the clinicopathological characteristics of age, gender and family history of gastric cancer, but not with differentiation, growth patterns, metastasis and TNM staging in patients with gastric cancer.
Title: Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer.

The following TYMS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TYMS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20911	NM_001071.4 Latest version!	Homo sapiens thymidylate synthetase (TYMS), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu104573	XM_024451242.1 Latest version!	Homo sapiens thymidylate synthetase (TYMS), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu102833	NM_001354867.2 Latest version!	Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu102836	NM_001354868.2 Latest version!	Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu102836	NM_001354868.1	Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu102833	NM_001354867.1	Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu20911	NM_001071.2	Homo sapiens thymidylate synthetase (TYMS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TYMS ( NM_001071.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001062.1 Homo sapiens thymidylate synthetase (TYMS), mRNA.

Price & Availability↑

CloneID	OHu20911
Clone ID Related Accession (Same CDS sequence)	NM_001071.2 , NM_001071.4
Accession Version	NM_001071.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-08-20
Organism	Homo sapiens(human)
Product	thymidylate synthase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001178.4, X02308.1 and BC083512.1. This sequence is a reference standard in the RefSeqGene project. On Apr 30, 2008 this sequence version replaced NM_001071.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB062290.1, SRR1163658.5616.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATTATT CAGGACAGGG AGTTGACCAA 
CTGCAAAGAG TGATTGACAC CATCAAAACC AACCCTGACG ACAGAAGAAT CATCATGTGC 
GCTTGGAATC CAAGAGATCT TCCTCTGATG GCGCTGCCTC CATGCCATGC CCTCTGCCAG 
TTCTATGTGG TGAACAGTGA GCTGTCCTGC CAGCTGTACC AGAGATCGGG AGACATGGGC 
CTCGGTGTGC CTTTCAACAT CGCCAGCTAC GCCCTGCTCA CGTACATGAT TGCGCACATC 
ACGGGCCTGA AGCCAGGTGA CTTTATACAC ACTTTGGGAG ATGCACATAT TTACCTGAAT 
CACATCGAGC CACTGAAAAT TCAGCTTCAG CGAGAACCCA GACCTTTCCC AAAGCTCAGG 
ATTCTTCGAA AAGTTGAGAA AATTGATGAC TTCAAAGCTG AAGACTTTCA GATTGAAGGG 
TACAATCCGC ATCCAACTAT TAAAATGGAA ATGGCTGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001062.1
CDS	140..1081
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001071.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001071.2

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATTATT CAGGACAGGG AGTTGACCAA 
CTGCAAAGAG TGATTGACAC CATCAAAACC AACCCTGACG ACAGAAGAAT CATCATGTGC 
GCTTGGAATC CAAGAGATCT TCCTCTGATG GCGCTGCCTC CATGCCATGC CCTCTGCCAG 
TTCTATGTGG TGAACAGTGA GCTGTCCTGC CAGCTGTACC AGAGATCGGG AGACATGGGC 
CTCGGTGTGC CTTTCAACAT CGCCAGCTAC GCCCTGCTCA CGTACATGAT TGCGCACATC 
ACGGGCCTGA AGCCAGGTGA CTTTATACAC ACTTTGGGAG ATGCACATAT TTACCTGAAT 
CACATCGAGC CACTGAAAAT TCAGCTTCAG CGAGAACCCA GACCTTTCCC AAAGCTCAGG 
ATTCTTCGAA AAGTTGAGAA AATTGATGAC TTCAAAGCTG AAGACTTTCA GATTGAAGGG 
TACAATCCGC ATCCAACTAT TAAAATGGAA ATGGCTGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( NM_001071.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001062.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20911
Clone ID Related Accession (Same CDS sequence)	NM_001071.2 , NM_001071.4
Accession Version	NM_001071.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY016886.1, AK223372.1, BC018858.2, BC083512.1 and HY269620.1. On Nov 23, 2018 this sequence version replaced NM_001071.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.118090.1, SRR1163658.307472.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000323274.15/ ENSP00000315644.10 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATTATT CAGGACAGGG AGTTGACCAA 
CTGCAAAGAG TGATTGACAC CATCAAAACC AACCCTGACG ACAGAAGAAT CATCATGTGC 
GCTTGGAATC CAAGAGATCT TCCTCTGATG GCGCTGCCTC CATGCCATGC CCTCTGCCAG 
TTCTATGTGG TGAACAGTGA GCTGTCCTGC CAGCTGTACC AGAGATCGGG AGACATGGGC 
CTCGGTGTGC CTTTCAACAT CGCCAGCTAC GCCCTGCTCA CGTACATGAT TGCGCACATC 
ACGGGCCTGA AGCCAGGTGA CTTTATACAC ACTTTGGGAG ATGCACATAT TTACCTGAAT 
CACATCGAGC CACTGAAAAT TCAGCTTCAG CGAGAACCCA GACCTTTCCC AAAGCTCAGG 
ATTCTTCGAA AAGTTGAGAA AATTGATGAC TTCAAAGCTG AAGACTTTCA GATTGAAGGG 
TACAATCCGC ATCCAACTAT TAAAATGGAA ATGGCTGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001062.1
CDS	91..1032
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001071.4
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001071.4

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATTATT CAGGACAGGG AGTTGACCAA 
CTGCAAAGAG TGATTGACAC CATCAAAACC AACCCTGACG ACAGAAGAAT CATCATGTGC 
GCTTGGAATC CAAGAGATCT TCCTCTGATG GCGCTGCCTC CATGCCATGC CCTCTGCCAG 
TTCTATGTGG TGAACAGTGA GCTGTCCTGC CAGCTGTACC AGAGATCGGG AGACATGGGC 
CTCGGTGTGC CTTTCAACAT CGCCAGCTAC GCCCTGCTCA CGTACATGAT TGCGCACATC 
ACGGGCCTGA AGCCAGGTGA CTTTATACAC ACTTTGGGAG ATGCACATAT TTACCTGAAT 
CACATCGAGC CACTGAAAAT TCAGCTTCAG CGAGAACCCA GACCTTTCCC AAAGCTCAGG 
ATTCTTCGAA AAGTTGAGAA AATTGATGAC TTCAAAGCTG AAGACTTTCA GATTGAAGGG 
TACAATCCGC ATCCAACTAT TAAAATGGAA ATGGCTGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( XM_024451242.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307010.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104573
Clone ID Related Accession (Same CDS sequence)	XM_024451242.1
Accession Version	XM_024451242.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAAGTT TAATATTATG TGTACTTTAT CACAATGAAA AAAGCTGCTG CGTGGGCCAA 
GTTACTTGTG CAGATTATTC AGGACAGGGA GTTGACCAAC TGCAAAGAGT GATTGACACC 
ATCAAAACCA ACCCTGACGA CAGAAGAATC ATCATGTGCG CTTGGAATCC AAGAGATCTT 
CCTCTGATGG CGCTGCCTCC ATGCCATGCC CTCTGCCAGT TCTATGTGGT GAACAGTGAG 
CTGTCCTGCC AGCTGTACCA GAGATCGGGA GACATGGGCC TCGGTGTGCC TTTCAACATC 
GCCAGCTACG CCCTGCTCAC GTACATGATT GCGCACATCA CGGGCCTGAA GCCAGGTGAC 
TTTATACACA CTTTGGGAGA TGCACATATT TACCTGAATC ACATCGAGCC ACTGAAAATT 
CAGCTTCAGC GAGAACCCAG ACCTTTCCCA AAGCTCAGGA TTCTTCGAAA AGTTGAGAAA 
ATTGATGACT TCAAAGCTGA AGACTTTCAG ATTGAAGGGT ACAATCCGCA TCCAACTATT 
AAAATGGAAA TGGCTGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307010.1
CDS	114..674
Translation	MASLILCVLYHNEKSCCVGQVTCADYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	XM_024451242.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451242.1

ORF Insert Sequence:

ATGGCAAGTT TAATATTATG TGTACTTTAT CACAATGAAA AAAGCTGCTG CGTGGGCCAA 
GTTACTTGTG CAGATTATTC AGGACAGGGA GTTGACCAAC TGCAAAGAGT GATTGACACC 
ATCAAAACCA ACCCTGACGA CAGAAGAATC ATCATGTGCG CTTGGAATCC AAGAGATCTT 
CCTCTGATGG CGCTGCCTCC ATGCCATGCC CTCTGCCAGT TCTATGTGGT GAACAGTGAG 
CTGTCCTGCC AGCTGTACCA GAGATCGGGA GACATGGGCC TCGGTGTGCC TTTCAACATC 
GCCAGCTACG CCCTGCTCAC GTACATGATT GCGCACATCA CGGGCCTGAA GCCAGGTGAC 
TTTATACACA CTTTGGGAGA TGCACATATT TACCTGAATC ACATCGAGCC ACTGAAAATT 
CAGCTTCAGC GAGAACCCAG ACCTTTCCCA AAGCTCAGGA TTCTTCGAAA AGTTGAGAAA 
ATTGATGACT TCAAAGCTGA AGACTTTCAG ATTGAAGGGT ACAATCCGCA TCCAACTATT 
AAAATGGAAA TGGCTGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( NM_001354867.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341796.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu102833
Clone ID Related Accession (Same CDS sequence)	NM_001354867.1 , NM_001354867.2
Accession Version	NM_001354867.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY016886.1, AK223372.1, AB077208.1, BC083512.1 and HY269620.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB077208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATCTTC CTCTGATGGC GCTGCCTCCA 
TGCCATGCCC TCTGCCAGTT CTATGTGGTG AACAGTGAGC TGTCCTGCCA GCTGTACCAG 
AGATCGGGAG ACATGGGCCT CGGTGTGCCT TTCAACATCG CCAGCTACGC CCTGCTCACG 
TACATGATTG CGCACATCAC GGGCCTGAAG CCAGGTGACT TTATACACAC TTTGGGAGAT 
GCACATATTT ACCTGAATCA CATCGAGCCA CTGAAAATTC AGCTTCAGCG AGAACCCAGA 
CCTTTCCCAA AGCTCAGGAT TCTTCGAAAA GTTGAGAAAA TTGATGACTT CAAAGCTGAA 
GACTTTCAGA TTGAAGGGTA CAATCCGCAT CCAACTATTA AAATGGAAAT GGCTGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341796.1
CDS	160..999
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001354867.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354867.1

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATCTTC CTCTGATGGC GCTGCCTCCA 
TGCCATGCCC TCTGCCAGTT CTATGTGGTG AACAGTGAGC TGTCCTGCCA GCTGTACCAG 
AGATCGGGAG ACATGGGCCT CGGTGTGCCT TTCAACATCG CCAGCTACGC CCTGCTCACG 
TACATGATTG CGCACATCAC GGGCCTGAAG CCAGGTGACT TTATACACAC TTTGGGAGAT 
GCACATATTT ACCTGAATCA CATCGAGCCA CTGAAAATTC AGCTTCAGCG AGAACCCAGA 
CCTTTCCCAA AGCTCAGGAT TCTTCGAAAA GTTGAGAAAA TTGATGACTT CAAAGCTGAA 
GACTTTCAGA TTGAAGGGTA CAATCCGCAT CCAACTATTA AAATGGAAAT GGCTGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( NM_001354867.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341796.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.

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CloneID	OHu102833
Clone ID Related Accession (Same CDS sequence)	NM_001354867.1 , NM_001354867.2
Accession Version	NM_001354867.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY016886.1, AK223372.1, AB077208.1, BC083512.1 and HY269620.1. On Jun 1, 2019 this sequence version replaced NM_001354867.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB077208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATCTTC CTCTGATGGC GCTGCCTCCA 
TGCCATGCCC TCTGCCAGTT CTATGTGGTG AACAGTGAGC TGTCCTGCCA GCTGTACCAG 
AGATCGGGAG ACATGGGCCT CGGTGTGCCT TTCAACATCG CCAGCTACGC CCTGCTCACG 
TACATGATTG CGCACATCAC GGGCCTGAAG CCAGGTGACT TTATACACAC TTTGGGAGAT 
GCACATATTT ACCTGAATCA CATCGAGCCA CTGAAAATTC AGCTTCAGCG AGAACCCAGA 
CCTTTCCCAA AGCTCAGGAT TCTTCGAAAA GTTGAGAAAA TTGATGACTT CAAAGCTGAA 
GACTTTCAGA TTGAAGGGTA CAATCCGCAT CCAACTATTA AAATGGAAAT GGCTGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341796.1
CDS	91..930
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001354867.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354867.2

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATGAA TTCCCTCTGC TGACAACCAA ACGTGTGTTC 
TGGAAGGGTG TTTTGGAGGA GTTGCTGTGG TTTATCAAGG GATCCACAAA TGCTAAAGAG 
CTGTCTTCCA AGGGAGTGAA AATCTGGGAT GCCAATGGAT CCCGAGACTT TTTGGACAGC 
CTGGGATTCT CCACCAGAGA AGAAGGGGAC TTGGGCCCAG TTTATGGCTT CCAGTGGAGG 
CATTTTGGGG CAGAATACAG AGATATGGAA TCAGATCTTC CTCTGATGGC GCTGCCTCCA 
TGCCATGCCC TCTGCCAGTT CTATGTGGTG AACAGTGAGC TGTCCTGCCA GCTGTACCAG 
AGATCGGGAG ACATGGGCCT CGGTGTGCCT TTCAACATCG CCAGCTACGC CCTGCTCACG 
TACATGATTG CGCACATCAC GGGCCTGAAG CCAGGTGACT TTATACACAC TTTGGGAGAT 
GCACATATTT ACCTGAATCA CATCGAGCCA CTGAAAATTC AGCTTCAGCG AGAACCCAGA 
CCTTTCCCAA AGCTCAGGAT TCTTCGAAAA GTTGAGAAAA TTGATGACTT CAAAGCTGAA 
GACTTTCAGA TTGAAGGGTA CAATCCGCAT CCAACTATTA AAATGGAAAT GGCTGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( NM_001354868.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341797.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu102836
Clone ID Related Accession (Same CDS sequence)	NM_001354868.2 , NM_001354868.1
Accession Version	NM_001354868.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY016886.1, AK223372.1, AB077207.1, BC083512.1 and HY269620.1. On May 31, 2019 this sequence version replaced NM_001354868.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.480246.1, DRR138506.6703.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATTAT TCAGGACAGG GAGTTGACCA ACTGCAAAGA 
GTGATTGACA CCATCAAAAC CAACCCTGAC GACAGAAGAA TCATCATGTG CGCTTGGAAT 
CCAAGAGATC TTCCTCTGAT GGCGCTGCCT CCATGCCATG CCCTCTGCCA GTTCTATGTG 
GTGAACAGTG AGCTGTCCTG CCAGCTGTAC CAGAGATCGG GAGACATGGG CCTCGGTGTG 
CCTTTCAACA TCGCCAGCTA CGCCCTGCTC ACGTACATGA TTGCGCACAT CACGGGCCTG 
AAGCCAGGTG ACTTTATACA CACTTTGGGA GATGCACATA TTTACCTGAA TCACATCGAG 
CCACTGAAAA TTCAGCTTCA GCGAGAACCC AGACCTTTCC CAAAGCTCAG GATTCTTCGA 
AAAGTTGAGA AAATTGATGA CTTCAAAGCT GAAGACTTTC AGATTGAAGG GTACAATCCG 
CATCCAACTA TTAAAATGGA AATGGCTGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341797.1
CDS	91..783
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001354868.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354868.2

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATTAT TCAGGACAGG GAGTTGACCA ACTGCAAAGA 
GTGATTGACA CCATCAAAAC CAACCCTGAC GACAGAAGAA TCATCATGTG CGCTTGGAAT 
CCAAGAGATC TTCCTCTGAT GGCGCTGCCT CCATGCCATG CCCTCTGCCA GTTCTATGTG 
GTGAACAGTG AGCTGTCCTG CCAGCTGTAC CAGAGATCGG GAGACATGGG CCTCGGTGTG 
CCTTTCAACA TCGCCAGCTA CGCCCTGCTC ACGTACATGA TTGCGCACAT CACGGGCCTG 
AAGCCAGGTG ACTTTATACA CACTTTGGGA GATGCACATA TTTACCTGAA TCACATCGAG 
CCACTGAAAA TTCAGCTTCA GCGAGAACCC AGACCTTTCC CAAAGCTCAG GATTCTTCGA 
AAAGTTGAGA AAATTGATGA CTTCAAAGCT GAAGACTTTC AGATTGAAGG GTACAATCCG 
CATCCAACTA TTAAAATGGA AATGGCTGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYMS ( NM_001354868.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341797.1 Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu102836
Clone ID Related Accession (Same CDS sequence)	NM_001354868.2 , NM_001354868.1
Accession Version	NM_001354868.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	thymidylate synthase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY016886.1, AK223372.1, AB077207.1, BC083512.1 and HY269620.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.480246.1, AB077207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATTAT TCAGGACAGG GAGTTGACCA ACTGCAAAGA 
GTGATTGACA CCATCAAAAC CAACCCTGAC GACAGAAGAA TCATCATGTG CGCTTGGAAT 
CCAAGAGATC TTCCTCTGAT GGCGCTGCCT CCATGCCATG CCCTCTGCCA GTTCTATGTG 
GTGAACAGTG AGCTGTCCTG CCAGCTGTAC CAGAGATCGG GAGACATGGG CCTCGGTGTG 
CCTTTCAACA TCGCCAGCTA CGCCCTGCTC ACGTACATGA TTGCGCACAT CACGGGCCTG 
AAGCCAGGTG ACTTTATACA CACTTTGGGA GATGCACATA TTTACCTGAA TCACATCGAG 
CCACTGAAAA TTCAGCTTCA GCGAGAACCC AGACCTTTCC CAAAGCTCAG GATTCTTCGA 
AAAGTTGAGA AAATTGATGA CTTCAAAGCT GAAGACTTTC AGATTGAAGG GTACAATCCG 
CATCCAACTA TTAAAATGGA AATGGCTGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341797.1
CDS	160..852
Translation	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV

Target ORF information:

RefSeq Version	NM_001354868.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thymidylate synthetase (TYMS), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354868.1

ORF Insert Sequence:

ATGCCTGTGG CCGGCTCGGA GCTGCCGCGC CGGCCCTTGC CCCCCGCCGC ACAGGAGCGG 
GACGCCGAGC CGCGTCCGCC GCACGGGGAG CTGCAGTACC TGGGGCAGAT CCAACACATC 
CTCCGCTGCG GCGTCAGGAA GGACGACCGC ACGGGCACCG GCACCCTGTC GGTATTCGGC 
ATGCAGGCGC GCTACAGCCT GAGAGATTAT TCAGGACAGG GAGTTGACCA ACTGCAAAGA 
GTGATTGACA CCATCAAAAC CAACCCTGAC GACAGAAGAA TCATCATGTG CGCTTGGAAT 
CCAAGAGATC TTCCTCTGAT GGCGCTGCCT CCATGCCATG CCCTCTGCCA GTTCTATGTG 
GTGAACAGTG AGCTGTCCTG CCAGCTGTAC CAGAGATCGG GAGACATGGG CCTCGGTGTG 
CCTTTCAACA TCGCCAGCTA CGCCCTGCTC ACGTACATGA TTGCGCACAT CACGGGCCTG 
AAGCCAGGTG ACTTTATACA CACTTTGGGA GATGCACATA TTTACCTGAA TCACATCGAG 
CCACTGAAAA TTCAGCTTCA GCGAGAACCC AGACCTTTCC CAAAGCTCAG GATTCTTCGA 
AAAGTTGAGA AAATTGATGA CTTCAAAGCT GAAGACTTTC AGATTGAAGG GTACAATCCG 
CATCCAACTA TTAAAATGGA AATGGCTGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Associative role of TYMS6bpdel polymorphism and resulting hyperhomocysteinemia in the pathogenesis of preterm delivery and associated complications: A study from Northeast India.
Gene627129-136(2017 Sep)
Tiwari D,Das CR,Bose PD,Bose S

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TYMS cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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