CCL23 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL23
Entrez Gene ID	6368
Full Name	C-C motif chemokine ligand 23
Synonyms	CK-BETA-8,CKb8,Ckb-8,Ckb-8-1,MIP-3,MIP3,MPIF-1,SCYA23,hmrp-2a
General protein information	Preferred Names C-C motif chemokine ligand 23 Names C-C motif chemokine 23 C6 beta-chemokine chemokine (C-C motif) ligand 23 macrophage inflammatory protein 3 myeloid progenitor inhibitory factor 1 small inducible cytokine subfamily A (Cys-Cys), member 23
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q12
Summary	This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
Disorder MIM:	602494

mRNA and Protein(s)

mRNA	Protein	Name
NM_145898.4	NP_665905.2	C-C motif chemokine 23 isoform CKbeta8 precursor
NM_145898.3	NP_665905.2	C-C motif chemokine 23 isoform CKbeta8 precursor
NM_005064.5	NP_005055.3	C-C motif chemokine 23 isoform CKbeta8-1 precursor
NM_005064.6	NP_005055.3	C-C motif chemokine 23 isoform CKbeta8-1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCL23	NP_665905.1
Pan troglodytes (chimpanzee)	CCL23	XP_001173941.1
	CCL23	NP_001028118.1

Gene Ontology
Bibliography

Related articles in PubMed

Tissue proteases convert CCL23 into potent monocyte chemoattractants in patients with chronic rhinosinusitis.
Poposki JA, Keswani A, Kim JK, Klingler AI, Suh LA, Norton J, Carter RG, Peters AT, Hulse KE, Grammer LC, Tan BK, Conley DB, Jaen JC, Schall TJ, Kern RC, Kato A
The Journal of allergy and clinical immunology137(4)1274-1277.e9(2016 Apr)

Effect of diabetes and oxidative stress on plasma CCL23 levels in patients with severe chronic kidney disease.
Pawlak K, My?liwiec M, Pawlak D
Polskie Archiwum Medycyny Wewnetrznej124(9)459-66(2014)

Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16.
Starr AE, Dufour A, Maier J, Overall CM
The Journal of biological chemistry287(8)5848-60(2012 Feb)

Proteolytic activation of alternative CCR1 ligands in inflammation.
Berahovich RD, Miao Z, Wang Y, Premack B, Howard MC, Schall TJ
Journal of immunology (Baltimore, Md. : 1950)174(11)7341-51(2005 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CCL23 is posttranslationally modified by trypsin-like serine proteases and CCL23(47-117) might be a major active form of CCL23 in nasal polyps with chronic rhinosinusitis.
Title: Tissue proteases convert CCL23 into potent monocyte chemoattractants in patients with chronic rhinosinusitis.

The coexistence of diabetes and oxidative stress independently affected CCL23 levels, while the presence of Cardiovascular disease and inflammation had no impact on its concentrations.
Title: Effect of diabetes and oxidative stress on plasma CCL23 levels in patients with severe chronic kidney disease.

ADAMTS 8, CCL23, and TNFSF15 are implicated in anti-angiogenic activities
Title: Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.

Data show CCL23 stimulates chemotaxis of human THP-1 monocytes and enhances release of MMP-2, and suggest it plays a role in atherogenesis.
Title: Potential involvement of CCL23 in atherosclerotic lesion formation/progression by the enhancement of chemotaxis, adhesion molecule expression, and MMP-2 release from monocytes.

Fresh eosinophils contained trace amounts of CCL23 protein. CCL23 was significantly released into the supernatant when the eosinophils were stimulated with GM-CSF or IL-5 but not with IFN-gamma or immobilized sIgA.
Title: Human eosinophils produce and release a novel chemokine, CCL23, in vitro.

The following CCL23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25274	NM_145898.4 Latest version!	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27979	NM_005064.6 Latest version!	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu25274	NM_145898.3	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27979	NM_005064.5	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL23 ( NM_145898.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_665905.2 Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Price & Availability↑

CloneID	OHu25274
Clone ID Related Accession (Same CDS sequence)	NM_145898.4 , NM_145898.3
Accession Version	NM_145898.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	C-C motif chemokine 23 isoform CKbeta8 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC244100.3, U58913.1, BC093970.1 and U85767.1. On May 31, 2019 this sequence version replaced NM_145898.3. Transcript Variant: This variant (CKbeta8) uses an alternate, in-frame splice site in the coding region, compared to transcript variant CKbeta8-1. This difference results in a shorter protein (isoform CKbeta8) compared to isoform CKbeta8-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138516.80552.1, U85767.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACAGATT CCATGCTACT AGTGCTGACT GCTGCATCTC CTACACCCCA 
CGAAGCATCC CGTGTTCACT CCTGGAGAGT TACTTTGAAA CGAACAGCGA GTGCTCCAAG 
CCGGGTGTCA TCTTCCTCAC CAAGAAGGGG CGACGTTTCT GTGCCAACCC CAGTGATAAG 
CAAGTTCAGG TTTGCATGAG AATGCTGAAG CTGGACACAC GGATCAAGAC CAGGAAGAAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_665905.2
CDS	76..438
Translation	MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Target ORF information:

RefSeq Version	NM_145898.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145898.4

ORF Insert Sequence:

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACAGATT CCATGCTACT AGTGCTGACT GCTGCATCTC CTACACCCCA 
CGAAGCATCC CGTGTTCACT CCTGGAGAGT TACTTTGAAA CGAACAGCGA GTGCTCCAAG 
CCGGGTGTCA TCTTCCTCAC CAAGAAGGGG CGACGTTTCT GTGCCAACCC CAGTGATAAG 
CAAGTTCAGG TTTGCATGAG AATGCTGAAG CTGGACACAC GGATCAAGAC CAGGAAGAAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL23 ( NM_145898.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_665905.2 Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Price & Availability↑

CloneID	OHu25274
Clone ID Related Accession (Same CDS sequence)	NM_145898.4 , NM_145898.3
Accession Version	NM_145898.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	C-C motif chemokine 23 isoform CKbeta8 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U58913.1, BC093970.1 and U85767.1. On May 9, 2014 this sequence version replaced NM_145898.2. Transcript Variant: This variant (CKbeta8) uses an alternate, in-frame splice site in the coding region, compared to transcript variant CKbeta8-1. This difference results in a shorter protein (isoform CKbeta8) compared to isoform CKbeta8-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U85767.1, BC093970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACAGATT CCATGCTACT AGTGCTGACT GCTGCATCTC CTACACCCCA 
CGAAGCATCC CGTGTTCACT CCTGGAGAGT TACTTTGAAA CGAACAGCGA GTGCTCCAAG 
CCGGGTGTCA TCTTCCTCAC CAAGAAGGGG CGACGTTTCT GTGCCAACCC CAGTGATAAG 
CAAGTTCAGG TTTGCATGAG AATGCTGAAG CTGGACACAC GGATCAAGAC CAGGAAGAAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_665905.2
CDS	72..434
Translation	MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Target ORF information:

RefSeq Version	NM_145898.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145898.3

ORF Insert Sequence:

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACAGATT CCATGCTACT AGTGCTGACT GCTGCATCTC CTACACCCCA 
CGAAGCATCC CGTGTTCACT CCTGGAGAGT TACTTTGAAA CGAACAGCGA GTGCTCCAAG 
CCGGGTGTCA TCTTCCTCAC CAAGAAGGGG CGACGTTTCT GTGCCAACCC CAGTGATAAG 
CAAGTTCAGG TTTGCATGAG AATGCTGAAG CTGGACACAC GGATCAAGAC CAGGAAGAAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL23 ( NM_005064.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005055.3 Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Price & Availability↑

CloneID	OHu27979
Clone ID Related Accession (Same CDS sequence)	NM_005064.5 , NM_005064.6
Accession Version	NM_005064.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	C-C motif chemokine 23 isoform CKbeta8-1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U58913.1, BC143310.1 and U85767.1. This sequence is a reference standard in the RefSeqGene project. On May 9, 2014 this sequence version replaced NM_005064.4. Transcript Variant: This variant (CKbeta8-1) represents the longer transcript and encodes the longer isoform (CKbeta8-1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U58913.1, BC143310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACATGCT CTGGAGGAGA AAGATTGGTC CTCAGATGAC CCTTTCTCAT 
GCTGCAGGAT TCCATGCTAC TAGTGCTGAC TGCTGCATCT CCTACACCCC ACGAAGCATC 
CCGTGTTCAC TCCTGGAGAG TTACTTTGAA ACGAACAGCG AGTGCTCCAA GCCGGGTGTC 
ATCTTCCTCA CCAAGAAGGG GCGACGTTTC TGTGCCAACC CCAGTGATAA GCAAGTTCAG 
GTTTGCATGA GAATGCTGAA GCTGGACACA CGGATCAAGA CCAGGAAGAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005055.3
CDS	72..485
Translation	MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Target ORF information:

RefSeq Version	NM_005064.5
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005064.5

ORF Insert Sequence:

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACATGCT CTGGAGGAGA AAGATTGGTC CTCAGATGAC CCTTTCTCAT 
GCTGCAGGAT TCCATGCTAC TAGTGCTGAC TGCTGCATCT CCTACACCCC ACGAAGCATC 
CCGTGTTCAC TCCTGGAGAG TTACTTTGAA ACGAACAGCG AGTGCTCCAA GCCGGGTGTC 
ATCTTCCTCA CCAAGAAGGG GCGACGTTTC TGTGCCAACC CCAGTGATAA GCAAGTTCAG 
GTTTGCATGA GAATGCTGAA GCTGGACACA CGGATCAAGA CCAGGAAGAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL23 ( NM_005064.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_005055.3 Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Price & Availability↑

CloneID	OHu27979
Clone ID Related Accession (Same CDS sequence)	NM_005064.5 , NM_005064.6
Accession Version	NM_005064.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	C-C motif chemokine 23 isoform CKbeta8-1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC244100.3, U58913.1, BC143310.1 and U85767.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005064.5. Transcript Variant: This variant (CKbeta8-1) represents the longer transcript and encodes the longer isoform (CKbeta8-1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U58913.1, BC143310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000615050.2/ ENSP00000481357.1 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACATGCT CTGGAGGAGA AAGATTGGTC CTCAGATGAC CCTTTCTCAT 
GCTGCAGGAT TCCATGCTAC TAGTGCTGAC TGCTGCATCT CCTACACCCC ACGAAGCATC 
CCGTGTTCAC TCCTGGAGAG TTACTTTGAA ACGAACAGCG AGTGCTCCAA GCCGGGTGTC 
ATCTTCCTCA CCAAGAAGGG GCGACGTTTC TGTGCCAACC CCAGTGATAA GCAAGTTCAG 
GTTTGCATGA GAATGCTGAA GCTGGACACA CGGATCAAGA CCAGGAAGAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005055.3
CDS	76..489
Translation	MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Target ORF information:

RefSeq Version	NM_005064.6
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 23 (CCL23), transcript variant CKbeta8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005064.6

ORF Insert Sequence:

ATGAAGGTCT CCGTGGCTGC CCTCTCCTGC CTCATGCTTG TTACTGCCCT TGGATCCCAG 
GCCCGGGTCA CAAAAGATGC AGAGACAGAG TTCATGATGT CAAAGCTTCC ATTGGAAAAT 
CCAGTACTTC TGGACATGCT CTGGAGGAGA AAGATTGGTC CTCAGATGAC CCTTTCTCAT 
GCTGCAGGAT TCCATGCTAC TAGTGCTGAC TGCTGCATCT CCTACACCCC ACGAAGCATC 
CCGTGTTCAC TCCTGGAGAG TTACTTTGAA ACGAACAGCG AGTGCTCCAA GCCGGGTGTC 
ATCTTCCTCA CCAAGAAGGG GCGACGTTTC TGTGCCAACC CCAGTGATAA GCAAGTTCAG 
GTTTGCATGA GAATGCTGAA GCTGGACACA CGGATCAAGA CCAGGAAGAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tissue proteases convert CCL23 into potent monocyte chemoattractants in patients with chronic rhinosinusitis.
The Journal of allergy and clinical immunology137(4)1274-1277.e9(2016 Apr)
Poposki JA,Keswani A,Kim JK,Klingler AI,Suh LA,Norton J,Carter RG,Peters AT,Hulse KE,Grammer LC,Tan BK,Conley DB,Jaen JC,Schall TJ,Kern RC,Kato A

Effect of diabetes and oxidative stress on plasma CCL23 levels in patients with severe chronic kidney disease.
Polskie Archiwum Medycyny Wewnetrznej124(9)459-66(2014)
Pawlak K,My?liwiec M,Pawlak D

Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16.
The Journal of biological chemistry287(8)5848-60(2012 Feb)
Starr AE,Dufour A,Maier J,Overall CM

Proteolytic activation of alternative CCR1 ligands in inflammation.
Journal of immunology (Baltimore, Md. : 1950)174(11)7341-51(2005 Jun)
Berahovich RD,Miao Z,Wang Y,Premack B,Howard MC,Schall TJ

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CCL23 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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