CYP4F11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP4F11
Entrez Gene ID	57834
Full Name	cytochrome P450 family 4 subfamily F member 11
Synonyms	CYPIVF11
General protein information	Preferred Names cytochrome P450 family 4 subfamily F member 11 Names phylloquinone omega-hydroxylase CYP4F11 3-hydroxy fatty acids omega-hydroxylase CYP4F11 cytochrome P450 4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 cytochrome P450, subfamily IVF, polypeptide 11
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.12
Summary	This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	611517

mRNA and Protein(s)

mRNA	Protein	Name
NM_001128932.1	NP_001122404.1	cytochrome P450 4F11 precursor
NM_021187.3	NP_067010.3	cytochrome P450 4F11 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CYP4F11	XP_003339356.1
Homo sapiens (human)	CYP4F11	NP_001122404.1
Mus musculus (house mouse)	Cyp4f40	NP_001095058.1
Gallus gallus (chicken)	CYP4F22	XP_003644077.2
Rattus norvegicus (Norway rat)	Cyp4f40	NP_001102830.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis.
Yi M, Cho SA, Min J, Kim DH, Shin JG, Lee SJ
Archives of biochemistry and biophysics62043-51(2017 Apr)

Cytochrome P450-dependent catabolism of vitamin K: ?-hydroxylation catalyzed by human CYP4F2 and CYP4F11.
Edson KZ, Prasad B, Unadkat JD, Suhara Y, Okano T, Guengerich FP, Rettie AE
Biochemistry52(46)8276-85(2013 Nov)

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.
Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J 2nd, Liu G, Spira A, Bell DA
PloS one5(8)e11934(2010 Aug)

Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Wang Y, Bell JC, Keeney DS, Strobel HW
Drug metabolism and disposition: the biological fate of chemicals38(1)100-7(2010 Jan)

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.
Dhar M, Sepkovic DW, Hirani V, Magnusson RP, Lasker JM
Journal of lipid research49(3)612-24(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that the metabolism of CYP4F11 substrates may be reduced in individuals carrying the CYP4F11 D315N genetic variant and individuals carrying the common D446N CYP4F11 variant likely exhibit comparable 20-HETE synthesis as individuals expressing wild-type CYP4F11.
Title: Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis.

Microsomal menaquinone-4 omega-hydroxylation activities correlated with the CYP4F2 V433M genotype but not the CYP4F11 D446N genotype
Title: Cytochrome P450-dependent catabolism of vitamin K: ?-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The CYP4F11 gene is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including retinoid X receptor and JNK signaling pathways.
Title: Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.

The following CYP4F11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP4F11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu06894	NM_001128932.1 Latest version!	Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu06894	NM_021187.3 Latest version!	Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP4F11 ( NM_001128932.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122404.1 Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06894
Clone ID Related Accession (Same CDS sequence)	NM_001128932.1 , NM_021187.3
Accession Version	NM_001128932.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	cytochrome P450 4F11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC016853.1, AK309292.1, BM727421.1, AK125714.1 and AC005336.1. Transcript Variant: This variant (2) lacks an internal segment in the 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.12569.1, SRR1660805.16198.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGCAGC TGAGCCTGTC CTGGCTGGGC CTCGGGCCCG TGGCAGCATC CCCGTGGCTG 
CTTCTGCTGC TGGTTGGGGG CTCCTGGCTC CTGGCCCGCG TCCTGGCCTG GACCTACACC 
TTCTATGACA ACTGCCGCCG CCTCCAGTGT TTTCCTCAAC CCCCGAAACA GAACTGGTTT 
TGGGGACACC AGGGCCTGGT CACTCCCACG GAAGAGGGCA TGAAGACATT GACCCAGCTG 
GTGACCACAT ATCCCCAGGG CTTTAAGTTG TGGCTGGGTC CTACCTTCCC CCTCCTCATT 
TTATGCCACC CTGACATTAT CCGGCCTATC ACCAGTGCCT CAGCTGCTGT CGCACCCAAG 
GATATGATTT TCTATGGCTT CCTGAAGCCC TGGCTGGGGG ATGGGCTCCT GCTGAGTGGT 
GGTGACAAGT GGAGCCGCCA CCGTCGGATG TTGACGCCTG CCTTCCATTT CAACATCTTG 
AAGCCTTATA TGAAGATTTT CAACAAGAGT GTGAACATCA TGCACGACAA GTGGCAGCGC 
CTGGCCTCAG AGGGCAGCGC CAGACTGGAC ATGTTTGAAC ACATCAGCCT CATGACCTTG 
GACAGTCTGC AGAAATGTGT CTTCAGCTTT GAAAGCAATT GTCAGGAGAA GCCCAGTGAA 
TATATTGCCG CCATCTTGGA GCTCAGTGCC TTTGTAGAAA AGAGAAACCA GCAGATTCTC 
TTGCACACGG ACTTCCTGTA TTATCTCACT CCTGATGGGC AGCGCTTCCG CAGGGCCTGC 
CACCTGGTGC ACGACTTCAC AGATGCCGTC ATCCAGGAGC GGCGCTGCAC CCTCCCCACT 
CAGGGTATTG ATGATTTCCT CAAGAACAAG GCAAAGTCCA AGACTTTAGA CTTCATTGAT 
GTGCTTCTGC TGAGCAAGGA TGAAGATGGG AAGGAATTGT CTGATGAGGA CATAAGAGCA 
GAAGCTGACA CCTTCATGTT TGAGGGCCAT GACACTACAG CCAGTGGTCT CTCCTGGGTC 
CTATACCACC TTGCAAAGCA CCCAGAATAC CAGGAACAGT GCCGGCAAGA AGTGCAAGAG 
CTTCTGAAGG ACCGTGAACC TATAGAGATT GAATGGGACG ACCTGGCCCA GCTGCCCTTC 
CTGACCATGT GCATTAAGGA GAGCCTGCGG TTGCATCCCC CAGTCCCGGT CATCTCCCGA 
TGTTGCACGC AGGACTTTGT GCTCCCAGAC GGCCGCGTCA TCCCCAAAGG CATTGTCTGC 
CTCATCAATA TTATCGGGAT CCATTACAAC CCAACTGTGT GGCCAGACCC TGAGGTCTAC 
GACCCCTTCC GTTTCGACCA AGAGAACATC AAGGAGAGGT CACCTCTGGC TTTTATTCCC 
TTCTCGGCAG GGCCCAGAAA CTGCATCGGG CAGGCGTTCG CCATGGCTGA GATGAAGGTG 
GTCCTGGCGC TCACCCTGCT GCACTTCCGC ATCCTGCCGA CCCACACTGA ACCCCGCAGG 
AAACCCGAGC TGATATTGCG CGCAGAGGGT GGACTTTGGC TGCGGGTGGA GCCCCTGGGT 
GCGAACTCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122404.1
CDS	37..1611
Translation	MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ

Target ORF information:

RefSeq Version	NM_001128932.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128932.1

ORF Insert Sequence:

ATGCCGCAGC TGAGCCTGTC CTGGCTGGGC CTCGGGCCCG TGGCAGCATC CCCGTGGCTG 
CTTCTGCTGC TGGTTGGGGG CTCCTGGCTC CTGGCCCGCG TCCTGGCCTG GACCTACACC 
TTCTATGACA ACTGCCGCCG CCTCCAGTGT TTTCCTCAAC CCCCGAAACA GAACTGGTTT 
TGGGGACACC AGGGCCTGGT CACTCCCACG GAAGAGGGCA TGAAGACATT GACCCAGCTG 
GTGACCACAT ATCCCCAGGG CTTTAAGTTG TGGCTGGGTC CTACCTTCCC CCTCCTCATT 
TTATGCCACC CTGACATTAT CCGGCCTATC ACCAGTGCCT CAGCTGCTGT CGCACCCAAG 
GATATGATTT TCTATGGCTT CCTGAAGCCC TGGCTGGGGG ATGGGCTCCT GCTGAGTGGT 
GGTGACAAGT GGAGCCGCCA CCGTCGGATG TTGACGCCTG CCTTCCATTT CAACATCTTG 
AAGCCTTATA TGAAGATTTT CAACAAGAGT GTGAACATCA TGCACGACAA GTGGCAGCGC 
CTGGCCTCAG AGGGCAGCGC CAGACTGGAC ATGTTTGAAC ACATCAGCCT CATGACCTTG 
GACAGTCTGC AGAAATGTGT CTTCAGCTTT GAAAGCAATT GTCAGGAGAA GCCCAGTGAA 
TATATTGCCG CCATCTTGGA GCTCAGTGCC TTTGTAGAAA AGAGAAACCA GCAGATTCTC 
TTGCACACGG ACTTCCTGTA TTATCTCACT CCTGATGGGC AGCGCTTCCG CAGGGCCTGC 
CACCTGGTGC ACGACTTCAC AGATGCCGTC ATCCAGGAGC GGCGCTGCAC CCTCCCCACT 
CAGGGTATTG ATGATTTCCT CAAGAACAAG GCAAAGTCCA AGACTTTAGA CTTCATTGAT 
GTGCTTCTGC TGAGCAAGGA TGAAGATGGG AAGGAATTGT CTGATGAGGA CATAAGAGCA 
GAAGCTGACA CCTTCATGTT TGAGGGCCAT GACACTACAG CCAGTGGTCT CTCCTGGGTC 
CTATACCACC TTGCAAAGCA CCCAGAATAC CAGGAACAGT GCCGGCAAGA AGTGCAAGAG 
CTTCTGAAGG ACCGTGAACC TATAGAGATT GAATGGGACG ACCTGGCCCA GCTGCCCTTC 
CTGACCATGT GCATTAAGGA GAGCCTGCGG TTGCATCCCC CAGTCCCGGT CATCTCCCGA 
TGTTGCACGC AGGACTTTGT GCTCCCAGAC GGCCGCGTCA TCCCCAAAGG CATTGTCTGC 
CTCATCAATA TTATCGGGAT CCATTACAAC CCAACTGTGT GGCCAGACCC TGAGGTCTAC 
GACCCCTTCC GTTTCGACCA AGAGAACATC AAGGAGAGGT CACCTCTGGC TTTTATTCCC 
TTCTCGGCAG GGCCCAGAAA CTGCATCGGG CAGGCGTTCG CCATGGCTGA GATGAAGGTG 
GTCCTGGCGC TCACCCTGCT GCACTTCCGC ATCCTGCCGA CCCACACTGA ACCCCGCAGG 
AAACCCGAGC TGATATTGCG CGCAGAGGGT GGACTTTGGC TGCGGGTGGA GCCCCTGGGT 
GCGAACTCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP4F11 ( NM_021187.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067010.3 Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06894
Clone ID Related Accession (Same CDS sequence)	NM_001128932.1 , NM_021187.3
Accession Version	NM_021187.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	cytochrome P450 4F11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC016853.1, DC345817.1, AK309292.1, BM727421.1, AK125714.1 and AC005336.1. This sequence is a reference standard in the RefSeqGene project. On Jun 27, 2008 this sequence version replaced NM_021187.2. Transcript Variant: This variant (1) is the longer transcript. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.216944.1, SRR1660809.181146.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153733 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGCAGC TGAGCCTGTC CTGGCTGGGC CTCGGGCCCG TGGCAGCATC CCCGTGGCTG 
CTTCTGCTGC TGGTTGGGGG CTCCTGGCTC CTGGCCCGCG TCCTGGCCTG GACCTACACC 
TTCTATGACA ACTGCCGCCG CCTCCAGTGT TTTCCTCAAC CCCCGAAACA GAACTGGTTT 
TGGGGACACC AGGGCCTGGT CACTCCCACG GAAGAGGGCA TGAAGACATT GACCCAGCTG 
GTGACCACAT ATCCCCAGGG CTTTAAGTTG TGGCTGGGTC CTACCTTCCC CCTCCTCATT 
TTATGCCACC CTGACATTAT CCGGCCTATC ACCAGTGCCT CAGCTGCTGT CGCACCCAAG 
GATATGATTT TCTATGGCTT CCTGAAGCCC TGGCTGGGGG ATGGGCTCCT GCTGAGTGGT 
GGTGACAAGT GGAGCCGCCA CCGTCGGATG TTGACGCCTG CCTTCCATTT CAACATCTTG 
AAGCCTTATA TGAAGATTTT CAACAAGAGT GTGAACATCA TGCACGACAA GTGGCAGCGC 
CTGGCCTCAG AGGGCAGCGC CAGACTGGAC ATGTTTGAAC ACATCAGCCT CATGACCTTG 
GACAGTCTGC AGAAATGTGT CTTCAGCTTT GAAAGCAATT GTCAGGAGAA GCCCAGTGAA 
TATATTGCCG CCATCTTGGA GCTCAGTGCC TTTGTAGAAA AGAGAAACCA GCAGATTCTC 
TTGCACACGG ACTTCCTGTA TTATCTCACT CCTGATGGGC AGCGCTTCCG CAGGGCCTGC 
CACCTGGTGC ACGACTTCAC AGATGCCGTC ATCCAGGAGC GGCGCTGCAC CCTCCCCACT 
CAGGGTATTG ATGATTTCCT CAAGAACAAG GCAAAGTCCA AGACTTTAGA CTTCATTGAT 
GTGCTTCTGC TGAGCAAGGA TGAAGATGGG AAGGAATTGT CTGATGAGGA CATAAGAGCA 
GAAGCTGACA CCTTCATGTT TGAGGGCCAT GACACTACAG CCAGTGGTCT CTCCTGGGTC 
CTATACCACC TTGCAAAGCA CCCAGAATAC CAGGAACAGT GCCGGCAAGA AGTGCAAGAG 
CTTCTGAAGG ACCGTGAACC TATAGAGATT GAATGGGACG ACCTGGCCCA GCTGCCCTTC 
CTGACCATGT GCATTAAGGA GAGCCTGCGG TTGCATCCCC CAGTCCCGGT CATCTCCCGA 
TGTTGCACGC AGGACTTTGT GCTCCCAGAC GGCCGCGTCA TCCCCAAAGG CATTGTCTGC 
CTCATCAATA TTATCGGGAT CCATTACAAC CCAACTGTGT GGCCAGACCC TGAGGTCTAC 
GACCCCTTCC GTTTCGACCA AGAGAACATC AAGGAGAGGT CACCTCTGGC TTTTATTCCC 
TTCTCGGCAG GGCCCAGAAA CTGCATCGGG CAGGCGTTCG CCATGGCTGA GATGAAGGTG 
GTCCTGGCGC TCACCCTGCT GCACTTCCGC ATCCTGCCGA CCCACACTGA ACCCCGCAGG 
AAACCCGAGC TGATATTGCG CGCAGAGGGT GGACTTTGGC TGCGGGTGGA GCCCCTGGGT 
GCGAACTCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067010.3
CDS	459..2033
Translation	MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ

Target ORF information:

RefSeq Version	NM_021187.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 4 subfamily F member 11 (CYP4F11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021187.3

ORF Insert Sequence:

ATGCCGCAGC TGAGCCTGTC CTGGCTGGGC CTCGGGCCCG TGGCAGCATC CCCGTGGCTG 
CTTCTGCTGC TGGTTGGGGG CTCCTGGCTC CTGGCCCGCG TCCTGGCCTG GACCTACACC 
TTCTATGACA ACTGCCGCCG CCTCCAGTGT TTTCCTCAAC CCCCGAAACA GAACTGGTTT 
TGGGGACACC AGGGCCTGGT CACTCCCACG GAAGAGGGCA TGAAGACATT GACCCAGCTG 
GTGACCACAT ATCCCCAGGG CTTTAAGTTG TGGCTGGGTC CTACCTTCCC CCTCCTCATT 
TTATGCCACC CTGACATTAT CCGGCCTATC ACCAGTGCCT CAGCTGCTGT CGCACCCAAG 
GATATGATTT TCTATGGCTT CCTGAAGCCC TGGCTGGGGG ATGGGCTCCT GCTGAGTGGT 
GGTGACAAGT GGAGCCGCCA CCGTCGGATG TTGACGCCTG CCTTCCATTT CAACATCTTG 
AAGCCTTATA TGAAGATTTT CAACAAGAGT GTGAACATCA TGCACGACAA GTGGCAGCGC 
CTGGCCTCAG AGGGCAGCGC CAGACTGGAC ATGTTTGAAC ACATCAGCCT CATGACCTTG 
GACAGTCTGC AGAAATGTGT CTTCAGCTTT GAAAGCAATT GTCAGGAGAA GCCCAGTGAA 
TATATTGCCG CCATCTTGGA GCTCAGTGCC TTTGTAGAAA AGAGAAACCA GCAGATTCTC 
TTGCACACGG ACTTCCTGTA TTATCTCACT CCTGATGGGC AGCGCTTCCG CAGGGCCTGC 
CACCTGGTGC ACGACTTCAC AGATGCCGTC ATCCAGGAGC GGCGCTGCAC CCTCCCCACT 
CAGGGTATTG ATGATTTCCT CAAGAACAAG GCAAAGTCCA AGACTTTAGA CTTCATTGAT 
GTGCTTCTGC TGAGCAAGGA TGAAGATGGG AAGGAATTGT CTGATGAGGA CATAAGAGCA 
GAAGCTGACA CCTTCATGTT TGAGGGCCAT GACACTACAG CCAGTGGTCT CTCCTGGGTC 
CTATACCACC TTGCAAAGCA CCCAGAATAC CAGGAACAGT GCCGGCAAGA AGTGCAAGAG 
CTTCTGAAGG ACCGTGAACC TATAGAGATT GAATGGGACG ACCTGGCCCA GCTGCCCTTC 
CTGACCATGT GCATTAAGGA GAGCCTGCGG TTGCATCCCC CAGTCCCGGT CATCTCCCGA 
TGTTGCACGC AGGACTTTGT GCTCCCAGAC GGCCGCGTCA TCCCCAAAGG CATTGTCTGC 
CTCATCAATA TTATCGGGAT CCATTACAAC CCAACTGTGT GGCCAGACCC TGAGGTCTAC 
GACCCCTTCC GTTTCGACCA AGAGAACATC AAGGAGAGGT CACCTCTGGC TTTTATTCCC 
TTCTCGGCAG GGCCCAGAAA CTGCATCGGG CAGGCGTTCG CCATGGCTGA GATGAAGGTG 
GTCCTGGCGC TCACCCTGCT GCACTTCCGC ATCCTGCCGA CCCACACTGA ACCCCGCAGG 
AAACCCGAGC TGATATTGCG CGCAGAGGGT GGACTTTGGC TGCGGGTGGA GCCCCTGGGT 
GCGAACTCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis.
Archives of biochemistry and biophysics62043-51(2017 Apr)
Yi M,Cho SA,Min J,Kim DH,Shin JG,Lee SJ

Cytochrome P450-dependent catabolism of vitamin K: ?-hydroxylation catalyzed by human CYP4F2 and CYP4F11.
Biochemistry52(46)8276-85(2013 Nov)
Edson KZ,Prasad B,Unadkat JD,Suhara Y,Okano T,Guengerich FP,Rettie AE

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.
PloS one5(8)e11934(2010 Aug)
Wang X,Chorley BN,Pittman GS,Kleeberger SR,Brothers J 2nd,Liu G,Spira A,Bell DA

Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Drug metabolism and disposition: the biological fate of chemicals38(1)100-7(2010 Jan)
Wang Y,Bell JC,Keeney DS,Strobel HW

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.
Journal of lipid research49(3)612-24(2008 Mar)
Dhar M,Sepkovic DW,Hirani V,Magnusson RP,Lasker JM

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CYP4F11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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