PACS1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PACS1
Entrez Gene ID	55690
Full Name	phosphofurin acidic cluster sorting protein 1
Synonyms	MRD17,SHMS
General protein information	Preferred Names phosphofurin acidic cluster sorting protein 1 Names phosphofurin acidic cluster sorting protein 1 PACS-1 cytosolic sorting protein PACS-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.1-q13.2
Summary	This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008].
Disorder MIM:	607492
Disorder Html:	Schuurs-Hoeijmakers syndrome, 615009 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011545162.1	XP_011543464.1	phosphofurin acidic cluster sorting protein 1 isoform X1
NM_018026.3	NP_060496.2	phosphofurin acidic cluster sorting protein 1
NM_018026.4	NP_060496.2	phosphofurin acidic cluster sorting protein 1
XM_011545164.2	XP_011543466.1	phosphofurin acidic cluster sorting protein 1 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	PACS1	NP_060496.2
Canis lupus familiaris (dog)	PACS1	XP_540837.3
Bos taurus (cattle)	PACS1	NP_001137342.1
	PACS1	XP_001111390.2
Pan troglodytes (chimpanzee)	PACS1	XP_001170787.1
Xenopus tropicalis (tropical clawed frog)	LOC100490541	XP_002935407.2
Gallus gallus (chicken)	PACS1	XP_004940210.1
Danio rerio (zebrafish)	pacs1a	NP_001092218.1
Mus musculus (house mouse)	Pacs1	NP_694769.2
Rattus norvegicus (Norway rat)	Pacs1	NP_599233.1

Gene Ontology
Bibliography

Related articles in PubMed

Association of the missense variant p.Arg203Trp in PACS1 as a cause of intellectual disability and seizures.
Stern D, Cho MT, Chikarmane R, Willaert R, Retterer K, Kendall F, Deardorff M, Hopkins S, Bedoukian E, Slavotinek A, Schrier Vergano S, Spangler B, McDonald M, McConkie-Rosell A, Burton BK, Kim KH, Oundjian N, Kronn D, Chandy N, Baskin B, Guillen Sacoto MJ, Wentzensen IM, McLaughlin HM, McKnight D, Chung WK
Clinical genetics92(2)221-223(2017 Aug)

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.
Thomas G, Aslan JE, Thomas L, Shinde P, Shinde U, Simmen T
Journal of cell science130(11)1865-1876(2017 Jun)

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization.
Brasacchio D, Alsop AE, Noori T, Lufti M, Iyer S, Simpson KJ, Bird PI, Kluck RM, Johnstone RW, Trapani JA
Cell death and differentiation24(6)961-970(2017 Jun)

Association Study of Three Gene Polymorphisms Recently Identified by a Genome-Wide Association Study with Obesity-Related Phenotypes in Chinese Children.
Song QY, Song JY, Wang Y, Wang S, Yang YD, Meng XR, Ma J, Wang HJ, Wang Y
Obesity facts10(3)179-190(2017)

Clinical delineation of the PACS1-related syndrome--Report on 19 patients.
Schuurs-Hoeijmakers JH, Landsverk ML, Foulds N, Kukolich MK, Gavrilova RH, Greville-Heygate S, Hanson-Kahn A, Bernstein JA, Glass J, Chitayat D, Burrow TA, Husami A, Collins K, Wusik K, van der Aa N, Kooy F, Brown KT, Gadzicki D, Kini U, Alvarez S, Fern?ndez-Ja?n A, McGehee F, Selby K, Tarailo-Graovac M, Van Allen M, van Karnebeek CD, Stavropoulos DJ, Marshall CR, Merico D, Gregor A, Zweier C, Hopkin RJ, Chu YW, Chung BH, de Vries BB, Devriendt K, Hurles ME, Brunner HG,
American journal of medical genetics. Part A170(3)670-5(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study showed for the first time that the rs564343 in phosphofurin acidic cluster sorting protein 1(PACS1) was associated with risk of severe obesity in Chinese children
Title: Association Study of Three Gene Polymorphisms Recently Identified by a Genome-Wide Association Study with Obesity-Related Phenotypes in Chinese Children.

Clinical description of the PACS1-related syndrome has been reported in 19 unrelated patients.
Title: Clinical delineation of the PACS1-related syndrome--Report on 19 patients.

PACS1 plays an important role in protein sorting for amyloidogenic-burden control via both SORLA-dependent and SORLA-independent mechanisms.
Title: SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes.

Single nucleotide polymorphisms in PAKS1 gene is associated with obesity.
Title: Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.

Our findings suggest that PACS1 is necessary for the formation of craniofacial structures and that perturbation of its functions results in a specific syndromic ID phenotype.
Title: Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.

The following PACS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PACS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26704	NM_018026.4 Latest version!	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu69633	XM_011545162.1 Latest version!	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu69635	XM_011545164.2 Latest version!	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu26704	NM_018026.3	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PACS1 ( NM_018026.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060496.2 Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.

Price & Availability↑

CloneID	OHu26704
Clone ID Related Accession (Same CDS sequence)	NM_018026.3 , NM_018026.4
Accession Version	NM_018026.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	phosphofurin acidic cluster sorting protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096644.1, BC010096.1 and BQ772654.1. This sequence is a reference standard in the RefSeqGene project. On Oct 15, 2011 this sequence version replaced NM_018026.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052577.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAAC GCGGAGGGGC GGGCGGTGGT CCCGGAGGCG CCGGGGGCGG CAGCGGCCAG 
CGGGGATCCG GGGTCGCCCA GTCCCCTCAG CAGCCGCCGC CGCAGCAGCA GCAGCAGCAG 
CCGCCGCAGC AGCCGACGCC CCCCAAGCTG GCCCAGGCCA CCTCGTCGTC CTCGTCCACC 
TCGGCGGCGG CTGCCTCCTC CTCGTCCTCG TCTACCTCCA CCTCCATGGC CGTGGCGGTG 
GCCTCGGGCT CCGCGCCTCC CGGTGGCCCG GGGCCAGGCC GCACCCCCGC CCCGGTGCAG 
ATGAACCTGT ACGCCACCTG GGAGGTGGAC CGGAGCTCGT CCAGCTGCGT GCCTAGGCTA 
TTCAGCTTGA CCCTGAAGAA ACTCGTCATG CTAAAAGAAA TGGACAAAGA TCTTAACTCA 
GTGGTCATCG CTGTGAAGCT GCAGGGTTCA AAAAGAATTC TTCGCTCCAA CGAGATCGTC 
CTTCCAGCTA GTGGACTGGT GGAAACAGAG CTCCAATTAA CCTTCTCCCT TCAGTACCCT 
CATTTCCTTA AGCGAGATGC CAACAAGCTG CAGATCATGC TGCAAAGGAG AAAACGTTAC 
AAGAATCGGA CCATCTTGGG CTATAAGACC TTGGCCGTGG GACTCATCAA CATGGCAGAG 
GTGATGCAGC ATCCTAATGA AGGCGCACTG GTGCTTGGCC TACACAGCAA CGTGAAGGAT 
GTCTCTGTGC CTGTGGCAGA AATAAAGATC TACTCCCTGT CCAGCCAACC CATTGACCAT 
GAAGGAATCA AATCCAAGCT TTCTGATCGT TCTCCTGATA TTGACAATTA TTCTGAGGAA 
GAGGAAGAGA GTTTCTCATC AGAACAGGAA GGCAGTGATG ATCCATTGCA TGGGCAGGAC 
TTGTTCTACG AAGACGAAGA TCTCCGGAAA GTGAAGAAGA CCCGGAGGAA ACTAACCTCA 
ACCTCTGCCA TCACAAGGCA ACCTAACATC AAACAGAAGT TTGTGGCCCT CCTGAAGCGG 
TTTAAAGTTT CAGATGAGGT GGGCTTTGGG CTGGAGCATG TGTCCCGCGA GCAGATCCGG 
GAAGTGGAAG AGGACTTGGA TGAATTGTAT GACAGTCTGG AGATGTACAA CCCCAGCGAC 
AGTGGCCCTG AGATGGAGGA GACAGAAAGC ATCCTCAGCA CGCCAAAGCC CAAGCTCAAG 
CCTTTCTTTG AGGGGATGTC GCAGTCCAGC TCCCAGACGG AGATTGGCAG CCTCAACAGC 
AAAGGCAGCC TCGGAAAAGA CACCACCAGC CCTATGGAAT TGGCTGCTCT AGAAAAAATT 
AAATCTACTT GGATTAAAAA CCAAGATGAC AGCTTGACTG AAACAGACAC TCTGGAAATC 
ACTGACCAGG ACATGTTTGG AGATGCCAGC ACGAGTCTGG TTGTGCCGGA GAAAGTCAAA 
ACTCCCATGA AGTCCAGTAA AACGGATCTC CAGGGCTCTG CCTCCCCCAG CAAAGTGGAG 
GGGGTGCACA CACCCCGGCA GAAGAGGAGC ACGCCCCTGA AGGAGCGGCA GCTCTCCAAG 
CCCCTAAGTG AGAGGACCAA CAGTTCCGAC AGCGAGCGCT CCCCAGATCT GGGCCACAGC 
ACGCAGATTC CAAGAAAGGT GGTGTATGAC CAGCTCAATC AGATCCTGGT GTCAGATGCA 
GCCCTCCCAG AAAATGTCAT TCTGGTGAAC ACCACTGACT GGCAGGGCCA GTATGTGGCT 
GAGCTGCTCC AGGACCAGCG GAAGCCTGTG GTGTGCACCT GCTCCACCGT GGAGGTCCAG 
GCCGTGCTGT CCGCCCTGCT CACCCGGATC CAGCGCTACT GCAACTGCAA CTCTTCCATG 
CCGAGGCCAG TGAAGGTGGC TGCTGTGGGA GGCCAGAGCT ACCTGAGCTC CATCCTCAGG 
TTCTTTGTCA AGTCCCTGGC CAACAAGACC TCCGACTGGC TTGGCTACAT GCGCTTCCTC 
ATCATCCCCC TCGGTTCTCA CCCTGTGGCC AAATACTTGG GGTCAGTCGA CAGTAAATAC 
AGTAGTTCCT TCCTGGATTC TGGTTGGAGA GATCTGTTCA GTCGCTCGGA GCCACCAGTG 
TCAGAGCAAC TGGACGTGGC AGGGCGGGTG ATGCAGTACG TCAACGGGGC AGCCACGACA 
CACCAGCTTC CCGTGGCCGA AGCCATGCTG ACTTGCCGGC ATAAGTTCCC TGATGAAGAC 
TCCTATCAGA AGTTTATTCC CTTCATTGGC GTGGTGAAGG TGGGTCTGGT TGAAGACTCT 
CCCTCCACAG CAGGCGATGG GGACGATTCT CCTGTGGTCA GCCTTACTGT GCCCTCCACA 
TCACCACCCT CCAGCTCGGG CCTGAGCCGA GACGCCACGG CCACCCCTCC CTCCTCCCCA 
TCTATGAGCA GCGCCCTGGC CATCGTGGGG AGCCCTAATA GCCCATATGG GGACGTGATT 
GGCCTCCAGG TGGACTACTG GCTGGGCCAC CCCGGGGAGC GGAGGAGGGA AGGCGACAAG 
AGGGACGCCA GCTCGAAGAA CACCCTCAAG AGTGTCTTCC GCTCAGTGCA GGTGTCCCGC 
CTGCCCCATA GTGGGGAGGC CCAGCTTTCT GGCACCATGG CCATGACTGT GGTCACCAAA 
GAAAAGAACA AGAAAGTTCC CACCATCTTC CTGAGCAAGA AACCCCGAGA AAAGGAGGTG 
GATTCTAAGA GCCAGGTCAT TGAAGGCATC AGCCGCCTCA TCTGCTCAGC CAAGCAGCAG 
CAGACTATGC TGAGAGTGTC CATCGATGGG GTCGAGTGGA GTGACATCAA GTTCTTCCAG 
CTGGCAGCCC AGTGGCCCAC CCATGTCAAG CACTTTCCAG TGGGACTCTT CAGTGGCAGC 
AAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060496.2
CDS	135..3026
Translation	MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT

Target ORF information:

RefSeq Version	NM_018026.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018026.3

ORF Insert Sequence:

ATGGCGGAAC GCGGAGGGGC GGGCGGTGGT CCCGGAGGCG CCGGGGGCGG CAGCGGCCAG 
CGGGGATCCG GGGTCGCCCA GTCCCCTCAG CAGCCGCCGC CGCAGCAGCA GCAGCAGCAG 
CCGCCGCAGC AGCCGACGCC CCCCAAGCTG GCCCAGGCCA CCTCGTCGTC CTCGTCCACC 
TCGGCGGCGG CTGCCTCCTC CTCGTCCTCG TCTACCTCCA CCTCCATGGC CGTGGCGGTG 
GCCTCGGGCT CCGCGCCTCC CGGTGGCCCG GGGCCAGGCC GCACCCCCGC CCCGGTGCAG 
ATGAACCTGT ACGCCACCTG GGAGGTGGAC CGGAGCTCGT CCAGCTGCGT GCCTAGGCTA 
TTCAGCTTGA CCCTGAAGAA ACTCGTCATG CTAAAAGAAA TGGACAAAGA TCTTAACTCA 
GTGGTCATCG CTGTGAAGCT GCAGGGTTCA AAAAGAATTC TTCGCTCCAA CGAGATCGTC 
CTTCCAGCTA GTGGACTGGT GGAAACAGAG CTCCAATTAA CCTTCTCCCT TCAGTACCCT 
CATTTCCTTA AGCGAGATGC CAACAAGCTG CAGATCATGC TGCAAAGGAG AAAACGTTAC 
AAGAATCGGA CCATCTTGGG CTATAAGACC TTGGCCGTGG GACTCATCAA CATGGCAGAG 
GTGATGCAGC ATCCTAATGA AGGCGCACTG GTGCTTGGCC TACACAGCAA CGTGAAGGAT 
GTCTCTGTGC CTGTGGCAGA AATAAAGATC TACTCCCTGT CCAGCCAACC CATTGACCAT 
GAAGGAATCA AATCCAAGCT TTCTGATCGT TCTCCTGATA TTGACAATTA TTCTGAGGAA 
GAGGAAGAGA GTTTCTCATC AGAACAGGAA GGCAGTGATG ATCCATTGCA TGGGCAGGAC 
TTGTTCTACG AAGACGAAGA TCTCCGGAAA GTGAAGAAGA CCCGGAGGAA ACTAACCTCA 
ACCTCTGCCA TCACAAGGCA ACCTAACATC AAACAGAAGT TTGTGGCCCT CCTGAAGCGG 
TTTAAAGTTT CAGATGAGGT GGGCTTTGGG CTGGAGCATG TGTCCCGCGA GCAGATCCGG 
GAAGTGGAAG AGGACTTGGA TGAATTGTAT GACAGTCTGG AGATGTACAA CCCCAGCGAC 
AGTGGCCCTG AGATGGAGGA GACAGAAAGC ATCCTCAGCA CGCCAAAGCC CAAGCTCAAG 
CCTTTCTTTG AGGGGATGTC GCAGTCCAGC TCCCAGACGG AGATTGGCAG CCTCAACAGC 
AAAGGCAGCC TCGGAAAAGA CACCACCAGC CCTATGGAAT TGGCTGCTCT AGAAAAAATT 
AAATCTACTT GGATTAAAAA CCAAGATGAC AGCTTGACTG AAACAGACAC TCTGGAAATC 
ACTGACCAGG ACATGTTTGG AGATGCCAGC ACGAGTCTGG TTGTGCCGGA GAAAGTCAAA 
ACTCCCATGA AGTCCAGTAA AACGGATCTC CAGGGCTCTG CCTCCCCCAG CAAAGTGGAG 
GGGGTGCACA CACCCCGGCA GAAGAGGAGC ACGCCCCTGA AGGAGCGGCA GCTCTCCAAG 
CCCCTAAGTG AGAGGACCAA CAGTTCCGAC AGCGAGCGCT CCCCAGATCT GGGCCACAGC 
ACGCAGATTC CAAGAAAGGT GGTGTATGAC CAGCTCAATC AGATCCTGGT GTCAGATGCA 
GCCCTCCCAG AAAATGTCAT TCTGGTGAAC ACCACTGACT GGCAGGGCCA GTATGTGGCT 
GAGCTGCTCC AGGACCAGCG GAAGCCTGTG GTGTGCACCT GCTCCACCGT GGAGGTCCAG 
GCCGTGCTGT CCGCCCTGCT CACCCGGATC CAGCGCTACT GCAACTGCAA CTCTTCCATG 
CCGAGGCCAG TGAAGGTGGC TGCTGTGGGA GGCCAGAGCT ACCTGAGCTC CATCCTCAGG 
TTCTTTGTCA AGTCCCTGGC CAACAAGACC TCCGACTGGC TTGGCTACAT GCGCTTCCTC 
ATCATCCCCC TCGGTTCTCA CCCTGTGGCC AAATACTTGG GGTCAGTCGA CAGTAAATAC 
AGTAGTTCCT TCCTGGATTC TGGTTGGAGA GATCTGTTCA GTCGCTCGGA GCCACCAGTG 
TCAGAGCAAC TGGACGTGGC AGGGCGGGTG ATGCAGTACG TCAACGGGGC AGCCACGACA 
CACCAGCTTC CCGTGGCCGA AGCCATGCTG ACTTGCCGGC ATAAGTTCCC TGATGAAGAC 
TCCTATCAGA AGTTTATTCC CTTCATTGGC GTGGTGAAGG TGGGTCTGGT TGAAGACTCT 
CCCTCCACAG CAGGCGATGG GGACGATTCT CCTGTGGTCA GCCTTACTGT GCCCTCCACA 
TCACCACCCT CCAGCTCGGG CCTGAGCCGA GACGCCACGG CCACCCCTCC CTCCTCCCCA 
TCTATGAGCA GCGCCCTGGC CATCGTGGGG AGCCCTAATA GCCCATATGG GGACGTGATT 
GGCCTCCAGG TGGACTACTG GCTGGGCCAC CCCGGGGAGC GGAGGAGGGA AGGCGACAAG 
AGGGACGCCA GCTCGAAGAA CACCCTCAAG AGTGTCTTCC GCTCAGTGCA GGTGTCCCGC 
CTGCCCCATA GTGGGGAGGC CCAGCTTTCT GGCACCATGG CCATGACTGT GGTCACCAAA 
GAAAAGAACA AGAAAGTTCC CACCATCTTC CTGAGCAAGA AACCCCGAGA AAAGGAGGTG 
GATTCTAAGA GCCAGGTCAT TGAAGGCATC AGCCGCCTCA TCTGCTCAGC CAAGCAGCAG 
CAGACTATGC TGAGAGTGTC CATCGATGGG GTCGAGTGGA GTGACATCAA GTTCTTCCAG 
CTGGCAGCCC AGTGGCCCAC CCATGTCAAG CACTTTCCAG TGGGACTCTT CAGTGGCAGC 
AAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PACS1 ( NM_018026.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060496.2 Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.

Price & Availability↑

CloneID	OHu26704
Clone ID Related Accession (Same CDS sequence)	NM_018026.3 , NM_018026.4
Accession Version	NM_018026.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	phosphofurin acidic cluster sorting protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006287.2, AK096644.1, BC010096.1 and BQ772654.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018026.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052577.1, BC010096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000320580.9/ ENSP00000316454.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAAC GCGGAGGGGC GGGCGGTGGT CCCGGAGGCG CCGGGGGCGG CAGCGGCCAG 
CGGGGATCCG GGGTCGCCCA GTCCCCTCAG CAGCCGCCGC CGCAGCAGCA GCAGCAGCAG 
CCGCCGCAGC AGCCGACGCC CCCCAAGCTG GCCCAGGCCA CCTCGTCGTC CTCGTCCACC 
TCGGCGGCGG CTGCCTCCTC CTCGTCCTCG TCTACCTCCA CCTCCATGGC CGTGGCGGTG 
GCCTCGGGCT CCGCGCCTCC CGGTGGCCCG GGGCCAGGCC GCACCCCCGC CCCGGTGCAG 
ATGAACCTGT ACGCCACCTG GGAGGTGGAC CGGAGCTCGT CCAGCTGCGT GCCTAGGCTA 
TTCAGCTTGA CCCTGAAGAA ACTCGTCATG CTAAAAGAAA TGGACAAAGA TCTTAACTCA 
GTGGTCATCG CTGTGAAGCT GCAGGGTTCA AAAAGAATTC TTCGCTCCAA CGAGATCGTC 
CTTCCAGCTA GTGGACTGGT GGAAACAGAG CTCCAATTAA CCTTCTCCCT TCAGTACCCT 
CATTTCCTTA AGCGAGATGC CAACAAGCTG CAGATCATGC TGCAAAGGAG AAAACGTTAC 
AAGAATCGGA CCATCTTGGG CTATAAGACC TTGGCCGTGG GACTCATCAA CATGGCAGAG 
GTGATGCAGC ATCCTAATGA AGGCGCACTG GTGCTTGGCC TACACAGCAA CGTGAAGGAT 
GTCTCTGTGC CTGTGGCAGA AATAAAGATC TACTCCCTGT CCAGCCAACC CATTGACCAT 
GAAGGAATCA AATCCAAGCT TTCTGATCGT TCTCCTGATA TTGACAATTA TTCTGAGGAA 
GAGGAAGAGA GTTTCTCATC AGAACAGGAA GGCAGTGATG ATCCATTGCA TGGGCAGGAC 
TTGTTCTACG AAGACGAAGA TCTCCGGAAA GTGAAGAAGA CCCGGAGGAA ACTAACCTCA 
ACCTCTGCCA TCACAAGGCA ACCTAACATC AAACAGAAGT TTGTGGCCCT CCTGAAGCGG 
TTTAAAGTTT CAGATGAGGT GGGCTTTGGG CTGGAGCATG TGTCCCGCGA GCAGATCCGG 
GAAGTGGAAG AGGACTTGGA TGAATTGTAT GACAGTCTGG AGATGTACAA CCCCAGCGAC 
AGTGGCCCTG AGATGGAGGA GACAGAAAGC ATCCTCAGCA CGCCAAAGCC CAAGCTCAAG 
CCTTTCTTTG AGGGGATGTC GCAGTCCAGC TCCCAGACGG AGATTGGCAG CCTCAACAGC 
AAAGGCAGCC TCGGAAAAGA CACCACCAGC CCTATGGAAT TGGCTGCTCT AGAAAAAATT 
AAATCTACTT GGATTAAAAA CCAAGATGAC AGCTTGACTG AAACAGACAC TCTGGAAATC 
ACTGACCAGG ACATGTTTGG AGATGCCAGC ACGAGTCTGG TTGTGCCGGA GAAAGTCAAA 
ACTCCCATGA AGTCCAGTAA AACGGATCTC CAGGGCTCTG CCTCCCCCAG CAAAGTGGAG 
GGGGTGCACA CACCCCGGCA GAAGAGGAGC ACGCCCCTGA AGGAGCGGCA GCTCTCCAAG 
CCCCTAAGTG AGAGGACCAA CAGTTCCGAC AGCGAGCGCT CCCCAGATCT GGGCCACAGC 
ACGCAGATTC CAAGAAAGGT GGTGTATGAC CAGCTCAATC AGATCCTGGT GTCAGATGCA 
GCCCTCCCAG AAAATGTCAT TCTGGTGAAC ACCACTGACT GGCAGGGCCA GTATGTGGCT 
GAGCTGCTCC AGGACCAGCG GAAGCCTGTG GTGTGCACCT GCTCCACCGT GGAGGTCCAG 
GCCGTGCTGT CCGCCCTGCT CACCCGGATC CAGCGCTACT GCAACTGCAA CTCTTCCATG 
CCGAGGCCAG TGAAGGTGGC TGCTGTGGGA GGCCAGAGCT ACCTGAGCTC CATCCTCAGG 
TTCTTTGTCA AGTCCCTGGC CAACAAGACC TCCGACTGGC TTGGCTACAT GCGCTTCCTC 
ATCATCCCCC TCGGTTCTCA CCCTGTGGCC AAATACTTGG GGTCAGTCGA CAGTAAATAC 
AGTAGTTCCT TCCTGGATTC TGGTTGGAGA GATCTGTTCA GTCGCTCGGA GCCACCAGTG 
TCAGAGCAAC TGGACGTGGC AGGGCGGGTG ATGCAGTACG TCAACGGGGC AGCCACGACA 
CACCAGCTTC CCGTGGCCGA AGCCATGCTG ACTTGCCGGC ATAAGTTCCC TGATGAAGAC 
TCCTATCAGA AGTTTATTCC CTTCATTGGC GTGGTGAAGG TGGGTCTGGT TGAAGACTCT 
CCCTCCACAG CAGGCGATGG GGACGATTCT CCTGTGGTCA GCCTTACTGT GCCCTCCACA 
TCACCACCCT CCAGCTCGGG CCTGAGCCGA GACGCCACGG CCACCCCTCC CTCCTCCCCA 
TCTATGAGCA GCGCCCTGGC CATCGTGGGG AGCCCTAATA GCCCATATGG GGACGTGATT 
GGCCTCCAGG TGGACTACTG GCTGGGCCAC CCCGGGGAGC GGAGGAGGGA AGGCGACAAG 
AGGGACGCCA GCTCGAAGAA CACCCTCAAG AGTGTCTTCC GCTCAGTGCA GGTGTCCCGC 
CTGCCCCATA GTGGGGAGGC CCAGCTTTCT GGCACCATGG CCATGACTGT GGTCACCAAA 
GAAAAGAACA AGAAAGTTCC CACCATCTTC CTGAGCAAGA AACCCCGAGA AAAGGAGGTG 
GATTCTAAGA GCCAGGTCAT TGAAGGCATC AGCCGCCTCA TCTGCTCAGC CAAGCAGCAG 
CAGACTATGC TGAGAGTGTC CATCGATGGG GTCGAGTGGA GTGACATCAA GTTCTTCCAG 
CTGGCAGCCC AGTGGCCCAC CCATGTCAAG CACTTTCCAG TGGGACTCTT CAGTGGCAGC 
AAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060496.2
CDS	216..3107
Translation	MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT

Target ORF information:

RefSeq Version	NM_018026.4
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018026.4

ORF Insert Sequence:

ATGGCGGAAC GCGGAGGGGC GGGCGGTGGT CCCGGAGGCG CCGGGGGCGG CAGCGGCCAG 
CGGGGATCCG GGGTCGCCCA GTCCCCTCAG CAGCCGCCGC CGCAGCAGCA GCAGCAGCAG 
CCGCCGCAGC AGCCGACGCC CCCCAAGCTG GCCCAGGCCA CCTCGTCGTC CTCGTCCACC 
TCGGCGGCGG CTGCCTCCTC CTCGTCCTCG TCTACCTCCA CCTCCATGGC CGTGGCGGTG 
GCCTCGGGCT CCGCGCCTCC CGGTGGCCCG GGGCCAGGCC GCACCCCCGC CCCGGTGCAG 
ATGAACCTGT ACGCCACCTG GGAGGTGGAC CGGAGCTCGT CCAGCTGCGT GCCTAGGCTA 
TTCAGCTTGA CCCTGAAGAA ACTCGTCATG CTAAAAGAAA TGGACAAAGA TCTTAACTCA 
GTGGTCATCG CTGTGAAGCT GCAGGGTTCA AAAAGAATTC TTCGCTCCAA CGAGATCGTC 
CTTCCAGCTA GTGGACTGGT GGAAACAGAG CTCCAATTAA CCTTCTCCCT TCAGTACCCT 
CATTTCCTTA AGCGAGATGC CAACAAGCTG CAGATCATGC TGCAAAGGAG AAAACGTTAC 
AAGAATCGGA CCATCTTGGG CTATAAGACC TTGGCCGTGG GACTCATCAA CATGGCAGAG 
GTGATGCAGC ATCCTAATGA AGGCGCACTG GTGCTTGGCC TACACAGCAA CGTGAAGGAT 
GTCTCTGTGC CTGTGGCAGA AATAAAGATC TACTCCCTGT CCAGCCAACC CATTGACCAT 
GAAGGAATCA AATCCAAGCT TTCTGATCGT TCTCCTGATA TTGACAATTA TTCTGAGGAA 
GAGGAAGAGA GTTTCTCATC AGAACAGGAA GGCAGTGATG ATCCATTGCA TGGGCAGGAC 
TTGTTCTACG AAGACGAAGA TCTCCGGAAA GTGAAGAAGA CCCGGAGGAA ACTAACCTCA 
ACCTCTGCCA TCACAAGGCA ACCTAACATC AAACAGAAGT TTGTGGCCCT CCTGAAGCGG 
TTTAAAGTTT CAGATGAGGT GGGCTTTGGG CTGGAGCATG TGTCCCGCGA GCAGATCCGG 
GAAGTGGAAG AGGACTTGGA TGAATTGTAT GACAGTCTGG AGATGTACAA CCCCAGCGAC 
AGTGGCCCTG AGATGGAGGA GACAGAAAGC ATCCTCAGCA CGCCAAAGCC CAAGCTCAAG 
CCTTTCTTTG AGGGGATGTC GCAGTCCAGC TCCCAGACGG AGATTGGCAG CCTCAACAGC 
AAAGGCAGCC TCGGAAAAGA CACCACCAGC CCTATGGAAT TGGCTGCTCT AGAAAAAATT 
AAATCTACTT GGATTAAAAA CCAAGATGAC AGCTTGACTG AAACAGACAC TCTGGAAATC 
ACTGACCAGG ACATGTTTGG AGATGCCAGC ACGAGTCTGG TTGTGCCGGA GAAAGTCAAA 
ACTCCCATGA AGTCCAGTAA AACGGATCTC CAGGGCTCTG CCTCCCCCAG CAAAGTGGAG 
GGGGTGCACA CACCCCGGCA GAAGAGGAGC ACGCCCCTGA AGGAGCGGCA GCTCTCCAAG 
CCCCTAAGTG AGAGGACCAA CAGTTCCGAC AGCGAGCGCT CCCCAGATCT GGGCCACAGC 
ACGCAGATTC CAAGAAAGGT GGTGTATGAC CAGCTCAATC AGATCCTGGT GTCAGATGCA 
GCCCTCCCAG AAAATGTCAT TCTGGTGAAC ACCACTGACT GGCAGGGCCA GTATGTGGCT 
GAGCTGCTCC AGGACCAGCG GAAGCCTGTG GTGTGCACCT GCTCCACCGT GGAGGTCCAG 
GCCGTGCTGT CCGCCCTGCT CACCCGGATC CAGCGCTACT GCAACTGCAA CTCTTCCATG 
CCGAGGCCAG TGAAGGTGGC TGCTGTGGGA GGCCAGAGCT ACCTGAGCTC CATCCTCAGG 
TTCTTTGTCA AGTCCCTGGC CAACAAGACC TCCGACTGGC TTGGCTACAT GCGCTTCCTC 
ATCATCCCCC TCGGTTCTCA CCCTGTGGCC AAATACTTGG GGTCAGTCGA CAGTAAATAC 
AGTAGTTCCT TCCTGGATTC TGGTTGGAGA GATCTGTTCA GTCGCTCGGA GCCACCAGTG 
TCAGAGCAAC TGGACGTGGC AGGGCGGGTG ATGCAGTACG TCAACGGGGC AGCCACGACA 
CACCAGCTTC CCGTGGCCGA AGCCATGCTG ACTTGCCGGC ATAAGTTCCC TGATGAAGAC 
TCCTATCAGA AGTTTATTCC CTTCATTGGC GTGGTGAAGG TGGGTCTGGT TGAAGACTCT 
CCCTCCACAG CAGGCGATGG GGACGATTCT CCTGTGGTCA GCCTTACTGT GCCCTCCACA 
TCACCACCCT CCAGCTCGGG CCTGAGCCGA GACGCCACGG CCACCCCTCC CTCCTCCCCA 
TCTATGAGCA GCGCCCTGGC CATCGTGGGG AGCCCTAATA GCCCATATGG GGACGTGATT 
GGCCTCCAGG TGGACTACTG GCTGGGCCAC CCCGGGGAGC GGAGGAGGGA AGGCGACAAG 
AGGGACGCCA GCTCGAAGAA CACCCTCAAG AGTGTCTTCC GCTCAGTGCA GGTGTCCCGC 
CTGCCCCATA GTGGGGAGGC CCAGCTTTCT GGCACCATGG CCATGACTGT GGTCACCAAA 
GAAAAGAACA AGAAAGTTCC CACCATCTTC CTGAGCAAGA AACCCCGAGA AAAGGAGGTG 
GATTCTAAGA GCCAGGTCAT TGAAGGCATC AGCCGCCTCA TCTGCTCAGC CAAGCAGCAG 
CAGACTATGC TGAGAGTGTC CATCGATGGG GTCGAGTGGA GTGACATCAA GTTCTTCCAG 
CTGGCAGCCC AGTGGCCCAC CCATGTCAAG CACTTTCCAG TGGGACTCTT CAGTGGCAGC 
AAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PACS1 ( XM_011545162.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543464.1 Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69633
Clone ID Related Accession (Same CDS sequence)	XM_011545162.1
Accession Version	XM_011545162.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2571bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphofurin acidic cluster sorting protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTC CACGTGGCTG CTTGGCTTCC TCACGGCTAT TCAGCTTGAC CCTGAAGAAA 
CTCGTCATGC TAAAAGAAAT GGACAAAGAT CTTAACTCAG TGGTCATCGC TGTGAAGCTG 
CAGGGTTCAA AAAGAATTCT TCGCTCCAAC GAGATCGTCC TTCCAGCTAG TGGACTGGTG 
GAAACAGAGC TCCAATTAAC CTTCTCCCTT CAGTACCCTC ATTTCCTTAA GCGAGATGCC 
AACAAGCTGC AGATCATGCT GCAAAGGAGA AAACGTTACA AGAATCGGAC CATCTTGGGC 
TATAAGACCT TGGCCGTGGG ACTCATCAAC ATGGCAGAGG TGATGCAGCA TCCTAATGAA 
GGCGCACTGG TGCTTGGCCT ACACAGCAAC GTGAAGGATG TCTCTGTGCC TGTGGCAGAA 
ATAAAGATCT ACTCCCTGTC CAGCCAACCC ATTGACCATG AAGGAATCAA ATCCAAGCTT 
TCTGATCGTT CTCCTGATAT TGACAATTAT TCTGAGGAAG AGGAAGAGAG TTTCTCATCA 
GAACAGGAAG GCAGTGATGA TCCATTGCAT GGGCAGGACT TGTTCTACGA AGACGAAGAT 
CTCCGGAAAG TGAAGAAGAC CCGGAGGAAA CTAACCTCAA CCTCTGCCAT CACAAGGCAA 
CCTAACATCA AACAGAAGTT TGTGGCCCTC CTGAAGCGGT TTAAAGTTTC AGATGAGGTG 
GGCTTTGGGC TGGAGCATGT GTCCCGCGAG CAGATCCGGG AAGTGGAAGA GGACTTGGAT 
GAATTGTATG ACAGTCTGGA GATGTACAAC CCCAGCGACA GTGGCCCTGA GATGGAGGAG 
ACAGAAAGCA TCCTCAGCAC GCCAAAGCCC AAGCTCAAGC CTTTCTTTGA GGGGATGTCG 
CAGTCCAGCT CCCAGACGGA GATTGGCAGC CTCAACAGCA AAGGCAGCCT CGGAAAAGAC 
ACCACCAGCC CTATGGAATT GGCTGCTCTA GAAAAAATTA AATCTACTTG GATTAAAAAC 
CAAGATGACA GCTTGACTGA AACAGACACT CTGGAAATCA CTGACCAGGA CATGTTTGGA 
GATGCCAGCA CGAGTCTGGT TGTGCCGGAG AAAGTCAAAA CTCCCATGAA GTCCAGTAAA 
ACGGATCTCC AGGGCTCTGC CTCCCCCAGC AAAGTGGAGG GGGTGCACAC ACCCCGGCAG 
AAGAGGAGCA CGCCCCTGAA GGAGCGGCAG CTCTCCAAGC CCCTAAGTGA GAGGACCAAC 
AGTTCCGACA GCGAGCGCTC CCCAGATCTG GGCCACAGCA CGCAGATTCC AAGAAAGGTG 
GTGTATGACC AGCTCAATCA GATCCTGGTG TCAGATGCAG CCCTCCCAGA AAATGTCATT 
CTGGTGAACA CCACTGACTG GCAGGGCCAG TATGTGGCTG AGCTGCTCCA GGACCAGCGG 
AAGCCTGTGG TGTGCACCTG CTCCACCGTG GAGGTCCAGG CCGTGCTGTC CGCCCTGCTC 
ACCCGGATCC AGCGCTACTG CAACTGCAAC TCTTCCATGC CGAGGCCAGT GAAGGTGGCT 
GCTGTGGGAG GCCAGAGCTA CCTGAGCTCC ATCCTCAGGT TCTTTGTCAA GTCCCTGGCC 
AACAAGACCT CCGACTGGCT TGGCTACATG CGCTTCCTCA TCATCCCCCT CGGTTCTCAC 
CCTGTGGCCA AATACTTGGG GTCAGTCGAC AGTAAATACA GTAGTTCCTT CCTGGATTCT 
GGTTGGAGAG ATCTGTTCAG TCGCTCGGAG CCACCAGTGT CAGAGCAACT GGACGTGGCA 
GGGCGGGTGA TGCAGTACGT CAACGGGGCA GCCACGACAC ACCAGCTTCC CGTGGCCGAA 
GCCATGCTGA CTTGCCGGCA TAAGTTCCCT GATGAAGACT CCTATCAGAA GTTTATTCCC 
TTCATTGGCG TGGTGAAGGT GGGTCTGGTT GAAGACTCTC CCTCCACAGC AGGCGATGGG 
GACGATTCTC CTGTGGTCAG CCTTACTGTG CCCTCCACAT CACCACCCTC CAGCTCGGGC 
CTGAGCCGAG ACGCCACGGC CACCCCTCCC TCCTCCCCAT CTATGAGCAG CGCCCTGGCC 
ATCGTGGGGA GCCCTAATAG CCCATATGGG GACGTGATTG GCCTCCAGGT GGACTACTGG 
CTGGGCCACC CCGGGGAGCG GAGGAGGGAA GGCGACAAGA GGGACGCCAG CTCGAAGAAC 
ACCCTCAAGA GTGTCTTCCG CTCAGTGCAG GTGTCCCGCC TGCCCCATAG TGGGGAGGCC 
CAGCTTTCTG GCACCATGGC CATGACTGTG GTCACCAAAG AAAAGAACAA GAAAGTTCCC 
ACCATCTTCC TGAGCAAGAA ACCCCGAGAA AAGGAGGTGG ATTCTAAGAG CCAGGTCATT 
GAAGGCATCA GCCGCCTCAT CTGCTCAGCC AAGCAGCAGC AGACTATGCT GAGAGTGTCC 
ATCGATGGGG TCGAGTGGAG TGACATCAAG TTCTTCCAGC TGGCAGCCCA GTGGCCCACC 
CATGTCAAGC ACTTTCCAGT GGGACTCTTC AGTGGCAGCA AGGCCACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543464.1
CDS	16..2586
Translation	MAFPRGCLASSRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT

Target ORF information:

RefSeq Version	XM_011545162.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545162.1

ORF Insert Sequence:

ATGGCCTTTC CACGTGGCTG CTTGGCTTCC TCACGGCTAT TCAGCTTGAC CCTGAAGAAA 
CTCGTCATGC TAAAAGAAAT GGACAAAGAT CTTAACTCAG TGGTCATCGC TGTGAAGCTG 
CAGGGTTCAA AAAGAATTCT TCGCTCCAAC GAGATCGTCC TTCCAGCTAG TGGACTGGTG 
GAAACAGAGC TCCAATTAAC CTTCTCCCTT CAGTACCCTC ATTTCCTTAA GCGAGATGCC 
AACAAGCTGC AGATCATGCT GCAAAGGAGA AAACGTTACA AGAATCGGAC CATCTTGGGC 
TATAAGACCT TGGCCGTGGG ACTCATCAAC ATGGCAGAGG TGATGCAGCA TCCTAATGAA 
GGCGCACTGG TGCTTGGCCT ACACAGCAAC GTGAAGGATG TCTCTGTGCC TGTGGCAGAA 
ATAAAGATCT ACTCCCTGTC CAGCCAACCC ATTGACCATG AAGGAATCAA ATCCAAGCTT 
TCTGATCGTT CTCCTGATAT TGACAATTAT TCTGAGGAAG AGGAAGAGAG TTTCTCATCA 
GAACAGGAAG GCAGTGATGA TCCATTGCAT GGGCAGGACT TGTTCTACGA AGACGAAGAT 
CTCCGGAAAG TGAAGAAGAC CCGGAGGAAA CTAACCTCAA CCTCTGCCAT CACAAGGCAA 
CCTAACATCA AACAGAAGTT TGTGGCCCTC CTGAAGCGGT TTAAAGTTTC AGATGAGGTG 
GGCTTTGGGC TGGAGCATGT GTCCCGCGAG CAGATCCGGG AAGTGGAAGA GGACTTGGAT 
GAATTGTATG ACAGTCTGGA GATGTACAAC CCCAGCGACA GTGGCCCTGA GATGGAGGAG 
ACAGAAAGCA TCCTCAGCAC GCCAAAGCCC AAGCTCAAGC CTTTCTTTGA GGGGATGTCG 
CAGTCCAGCT CCCAGACGGA GATTGGCAGC CTCAACAGCA AAGGCAGCCT CGGAAAAGAC 
ACCACCAGCC CTATGGAATT GGCTGCTCTA GAAAAAATTA AATCTACTTG GATTAAAAAC 
CAAGATGACA GCTTGACTGA AACAGACACT CTGGAAATCA CTGACCAGGA CATGTTTGGA 
GATGCCAGCA CGAGTCTGGT TGTGCCGGAG AAAGTCAAAA CTCCCATGAA GTCCAGTAAA 
ACGGATCTCC AGGGCTCTGC CTCCCCCAGC AAAGTGGAGG GGGTGCACAC ACCCCGGCAG 
AAGAGGAGCA CGCCCCTGAA GGAGCGGCAG CTCTCCAAGC CCCTAAGTGA GAGGACCAAC 
AGTTCCGACA GCGAGCGCTC CCCAGATCTG GGCCACAGCA CGCAGATTCC AAGAAAGGTG 
GTGTATGACC AGCTCAATCA GATCCTGGTG TCAGATGCAG CCCTCCCAGA AAATGTCATT 
CTGGTGAACA CCACTGACTG GCAGGGCCAG TATGTGGCTG AGCTGCTCCA GGACCAGCGG 
AAGCCTGTGG TGTGCACCTG CTCCACCGTG GAGGTCCAGG CCGTGCTGTC CGCCCTGCTC 
ACCCGGATCC AGCGCTACTG CAACTGCAAC TCTTCCATGC CGAGGCCAGT GAAGGTGGCT 
GCTGTGGGAG GCCAGAGCTA CCTGAGCTCC ATCCTCAGGT TCTTTGTCAA GTCCCTGGCC 
AACAAGACCT CCGACTGGCT TGGCTACATG CGCTTCCTCA TCATCCCCCT CGGTTCTCAC 
CCTGTGGCCA AATACTTGGG GTCAGTCGAC AGTAAATACA GTAGTTCCTT CCTGGATTCT 
GGTTGGAGAG ATCTGTTCAG TCGCTCGGAG CCACCAGTGT CAGAGCAACT GGACGTGGCA 
GGGCGGGTGA TGCAGTACGT CAACGGGGCA GCCACGACAC ACCAGCTTCC CGTGGCCGAA 
GCCATGCTGA CTTGCCGGCA TAAGTTCCCT GATGAAGACT CCTATCAGAA GTTTATTCCC 
TTCATTGGCG TGGTGAAGGT GGGTCTGGTT GAAGACTCTC CCTCCACAGC AGGCGATGGG 
GACGATTCTC CTGTGGTCAG CCTTACTGTG CCCTCCACAT CACCACCCTC CAGCTCGGGC 
CTGAGCCGAG ACGCCACGGC CACCCCTCCC TCCTCCCCAT CTATGAGCAG CGCCCTGGCC 
ATCGTGGGGA GCCCTAATAG CCCATATGGG GACGTGATTG GCCTCCAGGT GGACTACTGG 
CTGGGCCACC CCGGGGAGCG GAGGAGGGAA GGCGACAAGA GGGACGCCAG CTCGAAGAAC 
ACCCTCAAGA GTGTCTTCCG CTCAGTGCAG GTGTCCCGCC TGCCCCATAG TGGGGAGGCC 
CAGCTTTCTG GCACCATGGC CATGACTGTG GTCACCAAAG AAAAGAACAA GAAAGTTCCC 
ACCATCTTCC TGAGCAAGAA ACCCCGAGAA AAGGAGGTGG ATTCTAAGAG CCAGGTCATT 
GAAGGCATCA GCCGCCTCAT CTGCTCAGCC AAGCAGCAGC AGACTATGCT GAGAGTGTCC 
ATCGATGGGG TCGAGTGGAG TGACATCAAG TTCTTCCAGC TGGCAGCCCA GTGGCCCACC 
CATGTCAAGC ACTTTCCAGT GGGACTCTTC AGTGGCAGCA AGGCCACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PACS1 ( XM_011545164.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543466.1 Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu69635
Clone ID Related Accession (Same CDS sequence)	XM_011545164.2
Accession Version	XM_011545164.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2553bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphofurin acidic cluster sorting protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545164.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACACA CATTTAGGCT ATTCAGCTTG ACCCTGAAGA AACTCGTCAT GCTAAAAGAA 
ATGGACAAAG ATCTTAACTC AGTGGTCATC GCTGTGAAGC TGCAGGGTTC AAAAAGAATT 
CTTCGCTCCA ACGAGATCGT CCTTCCAGCT AGTGGACTGG TGGAAACAGA GCTCCAATTA 
ACCTTCTCCC TTCAGTACCC TCATTTCCTT AAGCGAGATG CCAACAAGCT GCAGATCATG 
CTGCAAAGGA GAAAACGTTA CAAGAATCGG ACCATCTTGG GCTATAAGAC CTTGGCCGTG 
GGACTCATCA ACATGGCAGA GGTGATGCAG CATCCTAATG AAGGCGCACT GGTGCTTGGC 
CTACACAGCA ACGTGAAGGA TGTCTCTGTG CCTGTGGCAG AAATAAAGAT CTACTCCCTG 
TCCAGCCAAC CCATTGACCA TGAAGGAATC AAATCCAAGC TTTCTGATCG TTCTCCTGAT 
ATTGACAATT ATTCTGAGGA AGAGGAAGAG AGTTTCTCAT CAGAACAGGA AGGCAGTGAT 
GATCCATTGC ATGGGCAGGA CTTGTTCTAC GAAGACGAAG ATCTCCGGAA AGTGAAGAAG 
ACCCGGAGGA AACTAACCTC AACCTCTGCC ATCACAAGGC AACCTAACAT CAAACAGAAG 
TTTGTGGCCC TCCTGAAGCG GTTTAAAGTT TCAGATGAGG TGGGCTTTGG GCTGGAGCAT 
GTGTCCCGCG AGCAGATCCG GGAAGTGGAA GAGGACTTGG ATGAATTGTA TGACAGTCTG 
GAGATGTACA ACCCCAGCGA CAGTGGCCCT GAGATGGAGG AGACAGAAAG CATCCTCAGC 
ACGCCAAAGC CCAAGCTCAA GCCTTTCTTT GAGGGGATGT CGCAGTCCAG CTCCCAGACG 
GAGATTGGCA GCCTCAACAG CAAAGGCAGC CTCGGAAAAG ACACCACCAG CCCTATGGAA 
TTGGCTGCTC TAGAAAAAAT TAAATCTACT TGGATTAAAA ACCAAGATGA CAGCTTGACT 
GAAACAGACA CTCTGGAAAT CACTGACCAG GACATGTTTG GAGATGCCAG CACGAGTCTG 
GTTGTGCCGG AGAAAGTCAA AACTCCCATG AAGTCCAGTA AAACGGATCT CCAGGGCTCT 
GCCTCCCCCA GCAAAGTGGA GGGGGTGCAC ACACCCCGGC AGAAGAGGAG CACGCCCCTG 
AAGGAGCGGC AGCTCTCCAA GCCCCTAAGT GAGAGGACCA ACAGTTCCGA CAGCGAGCGC 
TCCCCAGATC TGGGCCACAG CACGCAGATT CCAAGAAAGG TGGTGTATGA CCAGCTCAAT 
CAGATCCTGG TGTCAGATGC AGCCCTCCCA GAAAATGTCA TTCTGGTGAA CACCACTGAC 
TGGCAGGGCC AGTATGTGGC TGAGCTGCTC CAGGACCAGC GGAAGCCTGT GGTGTGCACC 
TGCTCCACCG TGGAGGTCCA GGCCGTGCTG TCCGCCCTGC TCACCCGGAT CCAGCGCTAC 
TGCAACTGCA ACTCTTCCAT GCCGAGGCCA GTGAAGGTGG CTGCTGTGGG AGGCCAGAGC 
TACCTGAGCT CCATCCTCAG GTTCTTTGTC AAGTCCCTGG CCAACAAGAC CTCCGACTGG 
CTTGGCTACA TGCGCTTCCT CATCATCCCC CTCGGTTCTC ACCCTGTGGC CAAATACTTG 
GGGTCAGTCG ACAGTAAATA CAGTAGTTCC TTCCTGGATT CTGGTTGGAG AGATCTGTTC 
AGTCGCTCGG AGCCACCAGT GTCAGAGCAA CTGGACGTGG CAGGGCGGGT GATGCAGTAC 
GTCAACGGGG CAGCCACGAC ACACCAGCTT CCCGTGGCCG AAGCCATGCT GACTTGCCGG 
CATAAGTTCC CTGATGAAGA CTCCTATCAG AAGTTTATTC CCTTCATTGG CGTGGTGAAG 
GTGGGTCTGG TTGAAGACTC TCCCTCCACA GCAGGCGATG GGGACGATTC TCCTGTGGTC 
AGCCTTACTG TGCCCTCCAC ATCACCACCC TCCAGCTCGG GCCTGAGCCG AGACGCCACG 
GCCACCCCTC CCTCCTCCCC ATCTATGAGC AGCGCCCTGG CCATCGTGGG GAGCCCTAAT 
AGCCCATATG GGGACGTGAT TGGCCTCCAG GTGGACTACT GGCTGGGCCA CCCCGGGGAG 
CGGAGGAGGG AAGGCGACAA GAGGGACGCC AGCTCGAAGA ACACCCTCAA GAGTGTCTTC 
CGCTCAGTGC AGGTGTCCCG CCTGCCCCAT AGTGGGGAGG CCCAGCTTTC TGGCACCATG 
GCCATGACTG TGGTCACCAA AGAAAAGAAC AAGAAAGTTC CCACCATCTT CCTGAGCAAG 
AAACCCCGAG AAAAGGAGGT GGATTCTAAG AGCCAGGTCA TTGAAGGCAT CAGCCGCCTC 
ATCTGCTCAG CCAAGCAGCA GCAGACTATG CTGAGAGTGT CCATCGATGG GGTCGAGTGG 
AGTGACATCA AGTTCTTCCA GCTGGCAGCC CAGTGGCCCA CCCATGTCAA GCACTTTCCA 
GTGGGACTCT TCAGTGGCAG CAAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543466.1
CDS	1342..3894
Translation	MEHTFRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT

Target ORF information:

RefSeq Version	XM_011545164.2
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphofurin acidic cluster sorting protein 1 (PACS1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545164.2

ORF Insert Sequence:

ATGGAACACA CATTTAGGCT ATTCAGCTTG ACCCTGAAGA AACTCGTCAT GCTAAAAGAA 
ATGGACAAAG ATCTTAACTC AGTGGTCATC GCTGTGAAGC TGCAGGGTTC AAAAAGAATT 
CTTCGCTCCA ACGAGATCGT CCTTCCAGCT AGTGGACTGG TGGAAACAGA GCTCCAATTA 
ACCTTCTCCC TTCAGTACCC TCATTTCCTT AAGCGAGATG CCAACAAGCT GCAGATCATG 
CTGCAAAGGA GAAAACGTTA CAAGAATCGG ACCATCTTGG GCTATAAGAC CTTGGCCGTG 
GGACTCATCA ACATGGCAGA GGTGATGCAG CATCCTAATG AAGGCGCACT GGTGCTTGGC 
CTACACAGCA ACGTGAAGGA TGTCTCTGTG CCTGTGGCAG AAATAAAGAT CTACTCCCTG 
TCCAGCCAAC CCATTGACCA TGAAGGAATC AAATCCAAGC TTTCTGATCG TTCTCCTGAT 
ATTGACAATT ATTCTGAGGA AGAGGAAGAG AGTTTCTCAT CAGAACAGGA AGGCAGTGAT 
GATCCATTGC ATGGGCAGGA CTTGTTCTAC GAAGACGAAG ATCTCCGGAA AGTGAAGAAG 
ACCCGGAGGA AACTAACCTC AACCTCTGCC ATCACAAGGC AACCTAACAT CAAACAGAAG 
TTTGTGGCCC TCCTGAAGCG GTTTAAAGTT TCAGATGAGG TGGGCTTTGG GCTGGAGCAT 
GTGTCCCGCG AGCAGATCCG GGAAGTGGAA GAGGACTTGG ATGAATTGTA TGACAGTCTG 
GAGATGTACA ACCCCAGCGA CAGTGGCCCT GAGATGGAGG AGACAGAAAG CATCCTCAGC 
ACGCCAAAGC CCAAGCTCAA GCCTTTCTTT GAGGGGATGT CGCAGTCCAG CTCCCAGACG 
GAGATTGGCA GCCTCAACAG CAAAGGCAGC CTCGGAAAAG ACACCACCAG CCCTATGGAA 
TTGGCTGCTC TAGAAAAAAT TAAATCTACT TGGATTAAAA ACCAAGATGA CAGCTTGACT 
GAAACAGACA CTCTGGAAAT CACTGACCAG GACATGTTTG GAGATGCCAG CACGAGTCTG 
GTTGTGCCGG AGAAAGTCAA AACTCCCATG AAGTCCAGTA AAACGGATCT CCAGGGCTCT 
GCCTCCCCCA GCAAAGTGGA GGGGGTGCAC ACACCCCGGC AGAAGAGGAG CACGCCCCTG 
AAGGAGCGGC AGCTCTCCAA GCCCCTAAGT GAGAGGACCA ACAGTTCCGA CAGCGAGCGC 
TCCCCAGATC TGGGCCACAG CACGCAGATT CCAAGAAAGG TGGTGTATGA CCAGCTCAAT 
CAGATCCTGG TGTCAGATGC AGCCCTCCCA GAAAATGTCA TTCTGGTGAA CACCACTGAC 
TGGCAGGGCC AGTATGTGGC TGAGCTGCTC CAGGACCAGC GGAAGCCTGT GGTGTGCACC 
TGCTCCACCG TGGAGGTCCA GGCCGTGCTG TCCGCCCTGC TCACCCGGAT CCAGCGCTAC 
TGCAACTGCA ACTCTTCCAT GCCGAGGCCA GTGAAGGTGG CTGCTGTGGG AGGCCAGAGC 
TACCTGAGCT CCATCCTCAG GTTCTTTGTC AAGTCCCTGG CCAACAAGAC CTCCGACTGG 
CTTGGCTACA TGCGCTTCCT CATCATCCCC CTCGGTTCTC ACCCTGTGGC CAAATACTTG 
GGGTCAGTCG ACAGTAAATA CAGTAGTTCC TTCCTGGATT CTGGTTGGAG AGATCTGTTC 
AGTCGCTCGG AGCCACCAGT GTCAGAGCAA CTGGACGTGG CAGGGCGGGT GATGCAGTAC 
GTCAACGGGG CAGCCACGAC ACACCAGCTT CCCGTGGCCG AAGCCATGCT GACTTGCCGG 
CATAAGTTCC CTGATGAAGA CTCCTATCAG AAGTTTATTC CCTTCATTGG CGTGGTGAAG 
GTGGGTCTGG TTGAAGACTC TCCCTCCACA GCAGGCGATG GGGACGATTC TCCTGTGGTC 
AGCCTTACTG TGCCCTCCAC ATCACCACCC TCCAGCTCGG GCCTGAGCCG AGACGCCACG 
GCCACCCCTC CCTCCTCCCC ATCTATGAGC AGCGCCCTGG CCATCGTGGG GAGCCCTAAT 
AGCCCATATG GGGACGTGAT TGGCCTCCAG GTGGACTACT GGCTGGGCCA CCCCGGGGAG 
CGGAGGAGGG AAGGCGACAA GAGGGACGCC AGCTCGAAGA ACACCCTCAA GAGTGTCTTC 
CGCTCAGTGC AGGTGTCCCG CCTGCCCCAT AGTGGGGAGG CCCAGCTTTC TGGCACCATG 
GCCATGACTG TGGTCACCAA AGAAAAGAAC AAGAAAGTTC CCACCATCTT CCTGAGCAAG 
AAACCCCGAG AAAAGGAGGT GGATTCTAAG AGCCAGGTCA TTGAAGGCAT CAGCCGCCTC 
ATCTGCTCAG CCAAGCAGCA GCAGACTATG CTGAGAGTGT CCATCGATGG GGTCGAGTGG 
AGTGACATCA AGTTCTTCCA GCTGGCAGCC CAGTGGCCCA CCCATGTCAA GCACTTTCCA 
GTGGGACTCT TCAGTGGCAG CAAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of the missense variant p.Arg203Trp in PACS1 as a cause of intellectual disability and seizures.
Clinical genetics92(2)221-223(2017 Aug)
Stern D,Cho MT,Chikarmane R,Willaert R,Retterer K,Kendall F,Deardorff M,Hopkins S,Bedoukian E,Slavotinek A,Schrier Vergano S,Spangler B,McDonald M,McConkie-Rosell A,Burton BK,Kim KH,Oundjian N,Kronn D,Chandy N,Baskin B,Guillen Sacoto MJ,Wentzensen IM,McLaughlin HM,McKnight D,Chung WK

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.
Journal of cell science130(11)1865-1876(2017 Jun)
Thomas G,Aslan JE,Thomas L,Shinde P,Shinde U,Simmen T

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization.
Cell death and differentiation24(6)961-970(2017 Jun)
Brasacchio D,Alsop AE,Noori T,Lufti M,Iyer S,Simpson KJ,Bird PI,Kluck RM,Johnstone RW,Trapani JA

Association Study of Three Gene Polymorphisms Recently Identified by a Genome-Wide Association Study with Obesity-Related Phenotypes in Chinese Children.
Obesity facts10(3)179-190(2017)
Song QY,Song JY,Wang Y,Wang S,Yang YD,Meng XR,Ma J,Wang HJ,Wang Y

Clinical delineation of the PACS1-related syndrome--Report on 19 patients.
American journal of medical genetics. Part A170(3)670-5(2016 Mar)
Schuurs-Hoeijmakers JH,Landsverk ML,Foulds N,Kukolich MK,Gavrilova RH,Greville-Heygate S,Hanson-Kahn A,Bernstein JA,Glass J,Chitayat D,Burrow TA,Husami A,Collins K,Wusik K,van der Aa N,Kooy F,Brown KT,Gadzicki D,Kini U,Alvarez S,Fern?ndez-Ja?n A,McGehee F,Selby K,Tarailo-Graovac M,Van Allen M,van Karnebeek CD,Stavropoulos DJ,Marshall CR,Merico D,Gregor A,Zweier C,Hopkin RJ,Chu YW,Chung BH,de Vries BB,Devriendt K,Hurles ME,Brunner HG,

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PACS1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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