pacs1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	pacs1a
Entrez Gene ID	569034
Full Name	phosphofurin acidic cluster sorting protein 1a
Synonyms	im:7146683,pacs1,zgc:162891
General protein information	Preferred Names phosphofurin acidic cluster sorting protein 1a Names phosphofurin acidic cluster sorting protein 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098748.1	NP_001092218.1	phosphofurin acidic cluster sorting protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PACS1	NP_060496.2
Canis lupus familiaris (dog)	PACS1	XP_540837.3
Bos taurus (cattle)	PACS1	NP_001137342.1
	PACS1	XP_001111390.2
Pan troglodytes (chimpanzee)	PACS1	XP_001170787.1
Xenopus tropicalis (tropical clawed frog)	LOC100490541	XP_002935407.2
Gallus gallus (chicken)	PACS1	XP_004940210.1
Danio rerio (zebrafish)	pacs1a	NP_001092218.1
Mus musculus (house mouse)	Pacs1	NP_694769.2
Rattus norvegicus (Norway rat)	Pacs1	NP_599233.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.
Schuurs-Hoeijmakers JH, Oh EC, Vissers LE, Swinkels ME, Gilissen C, Willemsen MA, Holvoet M, Steehouwer M, Veltman JA, de Vries BB, van Bokhoven H, de Brouwer AP, Katsanis N, Devriendt K, Brunner HG
American journal of human genetics91(6)1122-7(2012 Dec)

The subcellular localization of TRPP2 modulates its function.
Fu X, Wang Y, Schetle N, Gao H, P?tz M, von Gersdorff G, Walz G, Kramer-Zucker AG
Journal of the American Society of Nephrology : JASN19(7)1342-51(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following pacs1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pacs1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33684	NM_001098748.1 Latest version!	Danio rerio phosphofurin acidic cluster sorting protein 1a (pacs1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

pacs1a ( NM_001098748.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001092218.1 Danio rerio phosphofurin acidic cluster sorting protein 1a (pacs1a), mRNA.

Price & Availability↑

CloneID	ODa33684
Clone ID Related Accession (Same CDS sequence)	NM_001098748.1
Accession Version	NM_001098748.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2730bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	phosphofurin acidic cluster sorting protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC142600.1. On Jun 20, 2007 this sequence version replaced XM_692396.2. ##Evidence-Data-START## Transcript exon combination :: BC142600.1, EF531598.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCGGAGC GCGGAGGACT TCAGCAGCAG CAGAGACCGG GAGTTCCGTC TCCCCACCTG 
CAGCCTCTCA GGACGGTCAC GATTTCTGCC AGTCGCCCGG TTCAGATGAA CCTGTTTGCG 
ACATGGGAGA TTGACAGCTC CTCTCCCAGC TGTGTGCCCA GACTTCTCAG TCTAACCCTT 
AAAAAACTAG TGATTCTGAA GGAGCTGGAC AGAGATCTCA CATCTGTTGT CATTGCAGTT 
AAACTCCAGG GTTCAAAACG CATTTTGCGG TCGAATGAAA TCATGCTGTC CTCTGCTGGC 
CTTACAGAGA CCGATCTTCA GCTGACATTC TCTCTTCAGT ATCCACACTT TTTGAAGAGA 
GATGCCAACA AGCTTCAAAT TATGCTCCAG AGACGCAAGA GATACAAGAA TCGCACTATT 
TTGGGATATA AGACCCTCGC ACTAGGAATG ATAAATATGG CTGAGGTGAT GCAGCACCCC 
ACTGAAGGAG CTCAGGTTTT GGGTTTGCAC ACGACAGTGA AGGACAAGCC AGTTATTGTT 
GCTGAGATCC GGGTCTATTC TCTTTCCAGT CAACCCATCG ACCCAGAGGG ACTGAAGACC 
AAGCTATCTG ATCGTTCACC AGACATTGAT AATTACTCGG AGGAGGAAGA GGAAAGCTAT 
TCGTCGGAGC AGGACGGCAG TGATGACCCT CTACAGGGGC AGTACCTTTA TGATGACGAG 
GATGAACTGA GGAAGAAGAA GCCTCGTCGT AAACTGCCCT CCACCGCCTC CATCACTAGA 
GCAAACCAAC CCAACATCAA GCAGAAGCTT ATGGCATTGG TGAAATGGTT CAAAGTTTCT 
GATGAGGTGG GCTTCGGTTT GGATCATGTG TCCCAAGAGC AGATCCGGGA TGTGGAAGAG 
GACCTGGATG AGCTCTATGA CAGTCTTGAG ATGTACAATC CCAGTGACAG CGGGCCAGAC 
CCAGAGGAGA CGGACAGCAT TATCAGCACC CCCAAACCCA AACTCCCGCC ATTTTTTGAA 
GGCATGTCTC AATCCAGCTC TCAGACGGAG TTTGGTAGCT TGAATAGCAG ATGCGGTCAC 
AGCAAAGACA AGCTGAGTCC TAGGGCTGAA CACACTGTGG TTGGTAAAAT TCAGCGTTCC 
CCCAGTGCAC ATCTGGAAGA TGCGTTCTCA GACGTGGACC CACTGGAATT CAATGAAGTG 
GAGGTAATTG CTGATGGGAC CCCTAGCATC ACTTTATCAG TGGCAGAGAG GCCCCGGACT 
CCACAGAGAA GTAACAGCAC CAATATGCCC TCTCCCAGGC TTGATGGCAG TCATACCCCC 
AAACAGAGAC GAGGGACTCC TATGAAGGAG AGACAGCTGT CCAAACCGCT CAGCGAACGC 
ACCAATAGTT CAGACAGCGA GAGATCACCC GAGCTCAGCC TCACCCCTCA GATGCCGAGG 
AAGATAGTGT ACGACCAGCT CAACCAGATT CTGCTGTCTG ACAGCACCCT TCCTGACAGC 
CTTATCTTGG TGAACGGCAG CGACTGGCAA GGACACTATG TGGCTGAGCT ACTACAGGCC 
CAGAAGCTGC CGGTGGTTTG CACCTGCTCC GGATCAGAAA TTCAAGCTGT TCTTTCAGCC 
CTGCTCACAC GCATACAGAA ATTCTGCAAC TGTAACTCCA TCATGCCCAA ACCGGTGAAG 
GTGGTGGCGG TTGGGGGTCA GAGCTACTTG GGAGCCGTTT TGAGATTCTT CGTTTCTCAG 
CTCGCCAACA AGATGTCTGA CTGGCTCAGC CACATAAAGT TCCTTGTGGT GCCTTTAGGC 
TCTCACCCTG TGGCCAAACA CCTGGGTTCT CTGGACAATC GCTACAGTTC TTCCTTTCTG 
GACAGCTCAT GGAGAGAATT TTTCAGCCGC ACAGAGCCAC CTCAGACTGA TTCTTTCTCT 
GCTGACATTG TGGATGTGGC AGGACGAATA ATACAGTACA TCAATGGATC TGTTGTTACC 
CATCAGCTCC CCATTGCAGA GGCCATGCTG ACCTGCAAAA ATAAGACGCA AGATGAAGAT 
TCCTGCCAAA ATTTTGTTCC ATTTGTGGGT GTGGTTAAGG TGGGATTGGT GGAACCCAAC 
CCAGGATCTT TAGGTGCAGA CTTCGAGGAG GGTCTGGCTT TGAGCTTGGC GGTTCCCTCA 
ACATCTCCAC CTGCTCATGG ATCTCCAACT GGGATGATGA AAGATTCTGC AACGCCGCCT 
CCGTCACCAT CACTAAGCGG AGGACTGGCT GCTTTAGGAA GCCCCAGCAT GCCACATGGT 
GTGGACGCCA TTGGGCTGCA GGTGGATTAC TGGGTGTCTT CAGGCATGGA GAAGCGCAAA 
GATGGAGACC CGAGAGACAG GAGTAATAAG ATCACATTGA GATGTGCATT CAGATCCTTG 
CAAGTTAGCA GATTATCGAG CTCCAGCTCC ACTGAGACTG GCTTTAACAC CATGTCCATG 
ACTGTGGTGA CCAAGGAGAA GAACAAGAAG GTTCCAACAA TATTCCTGGG GAAGAAGCCG 
AAAGAAAGAG ACACCGAGTC GAAGAGTCAG ATCATTGAAG GCATCACCAG ACTCATCTGC 
TCTGCCAAGA ATCAACAAAC CAGTTTAAAA GTGTCTGTAG ATGGGATGGA GTGGAATGAT 
GTGAAGTTCT TCCAGCTGGC GTCTCAGTGG CCTACTCATG TCAAGTACAT CCCCGTGGGG 
CTGTTCGGCT ACAACAAACC GCCCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092218.1
CDS	215..2944
Translation	MSERGGLQQQQRPGVPSPHLQPLRTVTISASRPVQMNLFATWEIDSSSPSCVPRLLSLTLKKLVILKELDRDLTSVVIAVKLQGSKRILRSNEIMLSSAGLTETDLQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLALGMINMAEVMQHPTEGAQVLGLHTTVKDKPVIVAEIRVYSLSSQPIDPEGLKTKLSDRSPDIDNYSEEEEESYSSEQDGSDDPLQGQYLYDDEDELRKKKPRRKLPSTASITRANQPNIKQKLMALVKWFKVSDEVGFGLDHVSQEQIRDVEEDLDELYDSLEMYNPSDSGPDPEETDSIISTPKPKLPPFFEGMSQSSSQTEFGSLNSRCGHSKDKLSPRAEHTVVGKIQRSPSAHLEDAFSDVDPLEFNEVEVIADGTPSITLSVAERPRTPQRSNSTNMPSPRLDGSHTPKQRRGTPMKERQLSKPLSERTNSSDSERSPELSLTPQMPRKIVYDQLNQILLSDSTLPDSLILVNGSDWQGHYVAELLQAQKLPVVCTCSGSEIQAVLSALLTRIQKFCNCNSIMPKPVKVVAVGGQSYLGAVLRFFVSQLANKMSDWLSHIKFLVVPLGSHPVAKHLGSLDNRYSSSFLDSSWREFFSRTEPPQTDSFSADIVDVAGRIIQYINGSVVTHQLPIAEAMLTCKNKTQDEDSCQNFVPFVGVVKVGLVEPNPGSLGADFEEGLALSLAVPSTSPPAHGSPTGMMKDSATPPPSPSLSGGLAALGSPSMPHGVDAIGLQVDYWVSSGMEKRKDGDPRDRSNKITLRCAFRSLQVSRLSSSSSTETGFNTMSMTVVTKEKNKKVPTIFLGKKPKERDTESKSQIIEGITRLICSAKNQQTSLKVSVDGMEWNDVKFFQLASQWPTHVKYIPVGLFGYNKPPS

Target ORF information:

RefSeq Version	NM_001098748.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio phosphofurin acidic cluster sorting protein 1a (pacs1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098748.1

ORF Insert Sequence:

ATGTCGGAGC GCGGAGGACT TCAGCAGCAG CAGAGACCGG GAGTTCCGTC TCCCCACCTG 
CAGCCTCTCA GGACGGTCAC GATTTCTGCC AGTCGCCCGG TTCAGATGAA CCTGTTTGCG 
ACATGGGAGA TTGACAGCTC CTCTCCCAGC TGTGTGCCCA GACTTCTCAG TCTAACCCTT 
AAAAAACTAG TGATTCTGAA GGAGCTGGAC AGAGATCTCA CATCTGTTGT CATTGCAGTT 
AAACTCCAGG GTTCAAAACG CATTTTGCGG TCGAATGAAA TCATGCTGTC CTCTGCTGGC 
CTTACAGAGA CCGATCTTCA GCTGACATTC TCTCTTCAGT ATCCACACTT TTTGAAGAGA 
GATGCCAACA AGCTTCAAAT TATGCTCCAG AGACGCAAGA GATACAAGAA TCGCACTATT 
TTGGGATATA AGACCCTCGC ACTAGGAATG ATAAATATGG CTGAGGTGAT GCAGCACCCC 
ACTGAAGGAG CTCAGGTTTT GGGTTTGCAC ACGACAGTGA AGGACAAGCC AGTTATTGTT 
GCTGAGATCC GGGTCTATTC TCTTTCCAGT CAACCCATCG ACCCAGAGGG ACTGAAGACC 
AAGCTATCTG ATCGTTCACC AGACATTGAT AATTACTCGG AGGAGGAAGA GGAAAGCTAT 
TCGTCGGAGC AGGACGGCAG TGATGACCCT CTACAGGGGC AGTACCTTTA TGATGACGAG 
GATGAACTGA GGAAGAAGAA GCCTCGTCGT AAACTGCCCT CCACCGCCTC CATCACTAGA 
GCAAACCAAC CCAACATCAA GCAGAAGCTT ATGGCATTGG TGAAATGGTT CAAAGTTTCT 
GATGAGGTGG GCTTCGGTTT GGATCATGTG TCCCAAGAGC AGATCCGGGA TGTGGAAGAG 
GACCTGGATG AGCTCTATGA CAGTCTTGAG ATGTACAATC CCAGTGACAG CGGGCCAGAC 
CCAGAGGAGA CGGACAGCAT TATCAGCACC CCCAAACCCA AACTCCCGCC ATTTTTTGAA 
GGCATGTCTC AATCCAGCTC TCAGACGGAG TTTGGTAGCT TGAATAGCAG ATGCGGTCAC 
AGCAAAGACA AGCTGAGTCC TAGGGCTGAA CACACTGTGG TTGGTAAAAT TCAGCGTTCC 
CCCAGTGCAC ATCTGGAAGA TGCGTTCTCA GACGTGGACC CACTGGAATT CAATGAAGTG 
GAGGTAATTG CTGATGGGAC CCCTAGCATC ACTTTATCAG TGGCAGAGAG GCCCCGGACT 
CCACAGAGAA GTAACAGCAC CAATATGCCC TCTCCCAGGC TTGATGGCAG TCATACCCCC 
AAACAGAGAC GAGGGACTCC TATGAAGGAG AGACAGCTGT CCAAACCGCT CAGCGAACGC 
ACCAATAGTT CAGACAGCGA GAGATCACCC GAGCTCAGCC TCACCCCTCA GATGCCGAGG 
AAGATAGTGT ACGACCAGCT CAACCAGATT CTGCTGTCTG ACAGCACCCT TCCTGACAGC 
CTTATCTTGG TGAACGGCAG CGACTGGCAA GGACACTATG TGGCTGAGCT ACTACAGGCC 
CAGAAGCTGC CGGTGGTTTG CACCTGCTCC GGATCAGAAA TTCAAGCTGT TCTTTCAGCC 
CTGCTCACAC GCATACAGAA ATTCTGCAAC TGTAACTCCA TCATGCCCAA ACCGGTGAAG 
GTGGTGGCGG TTGGGGGTCA GAGCTACTTG GGAGCCGTTT TGAGATTCTT CGTTTCTCAG 
CTCGCCAACA AGATGTCTGA CTGGCTCAGC CACATAAAGT TCCTTGTGGT GCCTTTAGGC 
TCTCACCCTG TGGCCAAACA CCTGGGTTCT CTGGACAATC GCTACAGTTC TTCCTTTCTG 
GACAGCTCAT GGAGAGAATT TTTCAGCCGC ACAGAGCCAC CTCAGACTGA TTCTTTCTCT 
GCTGACATTG TGGATGTGGC AGGACGAATA ATACAGTACA TCAATGGATC TGTTGTTACC 
CATCAGCTCC CCATTGCAGA GGCCATGCTG ACCTGCAAAA ATAAGACGCA AGATGAAGAT 
TCCTGCCAAA ATTTTGTTCC ATTTGTGGGT GTGGTTAAGG TGGGATTGGT GGAACCCAAC 
CCAGGATCTT TAGGTGCAGA CTTCGAGGAG GGTCTGGCTT TGAGCTTGGC GGTTCCCTCA 
ACATCTCCAC CTGCTCATGG ATCTCCAACT GGGATGATGA AAGATTCTGC AACGCCGCCT 
CCGTCACCAT CACTAAGCGG AGGACTGGCT GCTTTAGGAA GCCCCAGCAT GCCACATGGT 
GTGGACGCCA TTGGGCTGCA GGTGGATTAC TGGGTGTCTT CAGGCATGGA GAAGCGCAAA 
GATGGAGACC CGAGAGACAG GAGTAATAAG ATCACATTGA GATGTGCATT CAGATCCTTG 
CAAGTTAGCA GATTATCGAG CTCCAGCTCC ACTGAGACTG GCTTTAACAC CATGTCCATG 
ACTGTGGTGA CCAAGGAGAA GAACAAGAAG GTTCCAACAA TATTCCTGGG GAAGAAGCCG 
AAAGAAAGAG ACACCGAGTC GAAGAGTCAG ATCATTGAAG GCATCACCAG ACTCATCTGC 
TCTGCCAAGA ATCAACAAAC CAGTTTAAAA GTGTCTGTAG ATGGGATGGA GTGGAATGAT 
GTGAAGTTCT TCCAGCTGGC GTCTCAGTGG CCTACTCATG TCAAGTACAT CCCCGTGGGG 
CTGTTCGGCT ACAACAAACC GCCCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.
American journal of human genetics91(6)1122-7(2012 Dec)
Schuurs-Hoeijmakers JH,Oh EC,Vissers LE,Swinkels ME,Gilissen C,Willemsen MA,Holvoet M,Steehouwer M,Veltman JA,de Vries BB,van Bokhoven H,de Brouwer AP,Katsanis N,Devriendt K,Brunner HG

The subcellular localization of TRPP2 modulates its function.
Journal of the American Society of Nephrology : JASN19(7)1342-51(2008 Jul)
Fu X,Wang Y,Schetle N,Gao H,P?tz M,von Gersdorff G,Walz G,Kramer-Zucker AG

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pacs1a cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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