TMEM127 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM127
Entrez Gene ID	55654
Full Name	transmembrane protein 127
General protein information	Preferred Names transmembrane protein 127 Names transmembrane protein 127
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q11.2
Summary	This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2010].
Disorder MIM:	613403
Disorder Html:	{Pheochromocytoma, susceptibility to}, 171300 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017004451.1	XP_016859940.1	transmembrane protein 127 isoform X2
XM_017004452.1	XP_016859941.1	transmembrane protein 127 isoform X2
NM_001193304.3	NP_001180233.1	transmembrane protein 127
NM_017849.4	NP_060319.1	transmembrane protein 127
NM_001193304.2	NP_001180233.1	transmembrane protein 127
NM_017849.3	NP_060319.1	transmembrane protein 127
XM_017004450.1	XP_016859939.1	transmembrane protein 127 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Tmem127	NP_001094448.1
Homo sapiens (human)	TMEM127	NP_001180233.1
Mus musculus (house mouse)	Tmem127	NP_780354.1
Gallus gallus (chicken)	TMEM127	XP_003643478.2
	TMEM127	XP_001097406.1
Bos taurus (cattle)	TMEM127	NP_001192692.1
Danio rerio (zebrafish)	tmem127	NP_001018360.1
Pan troglodytes (chimpanzee)	TMEM127	XP_001148102.1
Canis lupus familiaris (dog)	TMEM127	XP_005630446.1
Xenopus tropicalis (tropical clawed frog)	tmem127	NP_001016932.1

Gene Ontology
Bibliography

Related articles in PubMed

Homozygous TMEM127-mutations in two patients with bilateral pheochromocytomas.
Eijkelenkamp K, Olderode-Berends MJW, van der Luijt RB, Robledo M, van Dooren M, Feelders RA, de Vries J, Kerstens MN, Links TP, van der Horst-Schrivers ANA
Clinical genetics(2017 Dec)

Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention.
Bausch B, Schiavi F, Ni Y, Welander J, Patocs A, Ngeow J, Wellner U, Malinoc A, Taschin E, Barbon G, Lanza V, S?derkvist P, Stenman A, Larsson C, Svahn F, Chen JL, Marquard J, Fraenkel M, Walter MA, Peczkowska M, Prejbisz A, Jarzab B, Hasse-Lazar K, Petersenn S, Moeller LC, Meyer A, Reisch N, Trupka A, Brase C, Galiano M, Preuss SF, Kwok P, Lendvai N, Berisha G, Makay ?, Boedeker CC, Weryha G, Racz K, Januszewicz A, Walz MK, Gimm O, Opocher G, Eng C, Neumann HPH,
JAMA oncology3(9)1204-1212(2017 Sep)

Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome.
Pat?cs A, Lendvai NK, Butz H, Liko I, Sapi Z, Szucs N, Toth G, Grolmusz VK, Igaz P, Toth M, R?cz K
Pathology oncology research : POR22(4)673-9(2016 Oct)

[Hereditary pheochromocytoma-associated syndromes. Part 1].
Yukina MY, Troshina EA, Beltsevich DG
Terapevticheskii arkhiv87(9)102-105(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The SDHA, TMEM127, MAX, and SDHAF2 genes contribute to hereditary pheochromocytoma and paraganglioma.
Title: Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention.

Of which 4 SDHB and 2 TMEM127 mutations were novel.
Title: Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome.

We report the first case of an individual with both a pheochromocytoma and a multilocular clear cell renal cell carcinoma driven by a novel germline mutation in the TMEM127 gene, with a sibling and 2 sons with the same mutation.
Title: Familial pheochromocytoma and renal cell carcinoma syndrome: TMEM127 as a novel candidate gene for the association.

Tumor multicentricity, nodular adrenomedullary hyperplasia, and the occurrence of symptoms more than a decade earlier than the age at diagnosis are novel findings in TMEM127-related pheochromocytoma.
Title: Penetrance and clinical features of pheochromocytoma in a six-generation family carrying a germline TMEM127 mutation.

Hereditary pheochromocytoma / paraganglioma associated with TMEM127 gene mutations has more aggressive course,bilateral adrenal involvement, higher recurrence rate, younger age at disease manifestations.
Title: [Hereditary pheochromocytoma-associated syndromes. Part 1].

The following TMEM127 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM127 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10702	NM_001193304.3 Latest version!	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10702	NM_017849.4 Latest version!	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu89645	XM_017004450.1 Latest version!	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu89646	XM_017004452.1 Latest version!	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu89646	XM_017004451.1 Latest version!	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu10702	NM_001193304.2	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10702	NM_017849.3	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM127 ( NM_001193304.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180233.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10702
Clone ID Related Accession (Same CDS sequence)	NM_001193304.3 , NM_017849.4 , NM_001193304.2 , NM_017849.3
Accession Version	NM_001193304.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Homo sapiens(human)
Product	transmembrane protein 127
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA212468.1, BC028575.1 and AC012307.8. On Jun 2, 2019 this sequence version replaced NM_001193304.2. Transcript Variant: This variant (2) has an alternate splice site, resulting in a shorter 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.155858.1, SRR1803612.143082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180233.1
CDS	238..954
Translation	MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	NM_001193304.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193304.3

ORF Insert Sequence:

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( NM_017849.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060319.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10702
Clone ID Related Accession (Same CDS sequence)	NM_001193304.3 , NM_017849.4 , NM_001193304.2 , NM_017849.3
Accession Version	NM_017849.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	transmembrane protein 127
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA212468.1, BC039892.1 and AC012307.8. On Nov 21, 2019 this sequence version replaced NM_017849.3. Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK000514.1, BC039892.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060319.1
CDS	261..977
Translation	MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	NM_017849.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017849.4

ORF Insert Sequence:

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( NM_001193304.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180233.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10702
Clone ID Related Accession (Same CDS sequence)	NM_001193304.3 , NM_017849.4 , NM_001193304.2 , NM_017849.3
Accession Version	NM_001193304.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	transmembrane protein 127
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA212468.1, BC028575.1 and AC012307.8. On Sep 2, 2010 this sequence version replaced NM_001193304.1. Transcript Variant: This variant (2) has an alternate splice site, resulting in a shorter 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.155858.1, SRR1803612.143082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180233.1
CDS	254..970
Translation	MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	NM_001193304.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193304.2

ORF Insert Sequence:

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( NM_017849.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060319.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10702
Clone ID Related Accession (Same CDS sequence)	NM_001193304.3 , NM_017849.4 , NM_001193304.2 , NM_017849.3
Accession Version	NM_017849.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	transmembrane protein 127
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA212468.1, BC039892.1 and AC012307.8. This sequence is a reference standard in the RefSeqGene project. On Sep 2, 2010 this sequence version replaced NM_017849.2. Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.103032.1, AK000514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152474, SAMN01820689 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060319.1
CDS	277..993
Translation	MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	NM_017849.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017849.3

ORF Insert Sequence:

ATGTACGCCC CCGGAGGCGC AGGGCTGCCC GGCGGGCGCC GGCGGAGGAG CCCGGGAGGC 
AGCGCTCTGC CCAAGCAGCC GGAGCGTAGC CTGGCCTCGG CCCTGCCTGG CGCCCTGTCT 
ATCACGGCGC TGTGCACTGC CCTCGCCGAG CCCGCCTGGT TGCACATCCA CGGAGGCACC 
TGTTCGCGCC AGGAGCTGGG GGTCTCCGAC GTGTTGGGCT ATGTGCACCC GGACCTGCTG 
AAAGATTTCT GCATGAATCC CCAGACAGTG CTGCTCCTGC GGGTCATCGC CGCCTTCTGT 
TTCCTGGGCA TCCTGTGTAG TCTCTCCGCT TTCCTTCTGG ATGTCTTTGG GCCGAAGCAT 
CCTGCTCTGA AGATCACTCG TCGCTATGCC TTCGCCCATA TCCTAACGGT TCTGCAGTGT 
GCCACCGTCA TTGGCTTTTC TTATTGGGCT TCTGAACTCA TCTTGGCCCA GCAGCAGCAG 
CATAAGAAGT ACCATGGATC CCAGGTCTAT GTCACCTTCG CCGTTAGCTT CTACCTGGTG 
GCAGGAGCTG GTGGAGCCTC AATCCTGGCC ACGGCAGCCA ACCTCCTGCG CCACTACCCC 
ACAGAGGAAG AGGAGCAGGC GCTGGAGCTG CTCTCAGAGA TGGAAGAGAA CGAGCCCTAC 
CCGGCGGAAT ATGAGGTCAT CAACCAGTTC CAGCCACCCC CTGCTTACAC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( XM_017004450.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859939.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X1, mRNA.

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CloneID	OHu89645
Clone ID Related Accession (Same CDS sequence)	XM_017004450.1
Accession Version	XM_017004450.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 127 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACTCTT TCCCTCCTGC CACATCCTGC CCCCTTCACA TTCACGAGTC ATTACCAGCC 
AGGGAAGGTC ATCCAAGTTT CCTCCAGCAT GGGCGATATC TTTGGGACCG AGACTTTCCT 
TGGAGAGCTG CTGAGAGCGG ACAGTCCCAA AAACAAGTGT CAAAGGGCCC AAGGGAAAGG 
GGACTGTGCC CTGGAGGCTC ACTTCACAGG GATCAGTGTT TGCTCCACAG CTGTAGCTCT 
GGGCTGACGC CCCCCAGACC CCTTCCTTCT CGGAGTGACC CGCCCCCAGG CCACCTGCTC 
CGGGGAGTTC TGTGCACTTT ACTCTTTGGA CTTCTCCTCA CGTGTGCCCT GGTTTTATGG 
GGAGAGGGAA TCGCTGTTGG GAAGGCAGAG CAGTTGCAAC CCTCTCTGCC CTTGCTTCAT 
GTGGCTGGAG CCCAGGCAAG GAGAGCAGGA GCCAGCGTGA GACTGAGGCC CCCTGGTGCC 
TATCAAGGAC CAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859939.1
CDS	776..1273
Translation	MYSFPPATSCPLHIHESLPAREGHPSFLQHGRYLWDRDFPWRAAESGQSQKQVSKGPRERGLCPGGSLHRDQCLLHSCSSGLTPPRPLPSRSDPPPGHLLRGVLCTLLFGLLLTCALVLWGEGIAVGKAEQLQPSLPLLHVAGAQARRAGASVRLRPPGAYQGPE

Target ORF information:

RefSeq Version	XM_017004450.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004450.1

ORF Insert Sequence:

ATGTACTCTT TCCCTCCTGC CACATCCTGC CCCCTTCACA TTCACGAGTC ATTACCAGCC 
AGGGAAGGTC ATCCAAGTTT CCTCCAGCAT GGGCGATATC TTTGGGACCG AGACTTTCCT 
TGGAGAGCTG CTGAGAGCGG ACAGTCCCAA AAACAAGTGT CAAAGGGCCC AAGGGAAAGG 
GGACTGTGCC CTGGAGGCTC ACTTCACAGG GATCAGTGTT TGCTCCACAG CTGTAGCTCT 
GGGCTGACGC CCCCCAGACC CCTTCCTTCT CGGAGTGACC CGCCCCCAGG CCACCTGCTC 
CGGGGAGTTC TGTGCACTTT ACTCTTTGGA CTTCTCCTCA CGTGTGCCCT GGTTTTATGG 
GGAGAGGGAA TCGCTGTTGG GAAGGCAGAG CAGTTGCAAC CCTCTCTGCC CTTGCTTCAT 
GTGGCTGGAG CCCAGGCAAG GAGAGCAGGA GCCAGCGTGA GACTGAGGCC CCCTGGTGCC 
TATCAAGGAC CAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( XM_017004451.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859940.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu89646
Clone ID Related Accession (Same CDS sequence)	XM_017004451.1 , XM_017004452.1
Accession Version	XM_017004451.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane protein 127 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATCCCC AGACAGTGCT GCTCCTGCGG GTCATCGCCG CCTTCTGTTT CCTGGGCATC 
CTGTGTAGTC TCTCCGCTTT CCTTCTGGAT GTCTTTGGGC CGAAGCATCC TGCTCTGAAG 
ATCACTCGTC GCTATGCCTT CGCCCATATC CTAACGGTTC TGCAGTGTGC CACCGTCATT 
GGCTTTTCTT ATTGGGCTTC TGAACTCATC TTGGCCCAGC AGCAGCAGCA TAAGAAGTAC 
CATGGATCCC AGGTCTATGT CACCTTCGCC GTTAGCTTCT ACCTGGTGGC AGGAGCTGGT 
GGAGCCTCAA TCCTGGCCAC GGCAGCCAAC CTCCTGCGCC ACTACCCCAC AGAGGAAGAG 
GAGCAGGCGC TGGAGCTGCT CTCAGAGATG GAAGAGAACG AGCCCTACCC GGCGGAATAT 
GAGGTCATCA ACCAGTTCCA GCCACCCCCT GCTTACACAC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859940.1
CDS	155..619
Translation	MNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	XM_017004451.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004451.1

ORF Insert Sequence:

ATGAATCCCC AGACAGTGCT GCTCCTGCGG GTCATCGCCG CCTTCTGTTT CCTGGGCATC 
CTGTGTAGTC TCTCCGCTTT CCTTCTGGAT GTCTTTGGGC CGAAGCATCC TGCTCTGAAG 
ATCACTCGTC GCTATGCCTT CGCCCATATC CTAACGGTTC TGCAGTGTGC CACCGTCATT 
GGCTTTTCTT ATTGGGCTTC TGAACTCATC TTGGCCCAGC AGCAGCAGCA TAAGAAGTAC 
CATGGATCCC AGGTCTATGT CACCTTCGCC GTTAGCTTCT ACCTGGTGGC AGGAGCTGGT 
GGAGCCTCAA TCCTGGCCAC GGCAGCCAAC CTCCTGCGCC ACTACCCCAC AGAGGAAGAG 
GAGCAGGCGC TGGAGCTGCT CTCAGAGATG GAAGAGAACG AGCCCTACCC GGCGGAATAT 
GAGGTCATCA ACCAGTTCCA GCCACCCCCT GCTTACACAC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM127 ( XM_017004452.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859941.1 Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu89646
Clone ID Related Accession (Same CDS sequence)	XM_017004451.1 , XM_017004452.1
Accession Version	XM_017004452.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 127 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATCCCC AGACAGTGCT GCTCCTGCGG GTCATCGCCG CCTTCTGTTT CCTGGGCATC 
CTGTGTAGTC TCTCCGCTTT CCTTCTGGAT GTCTTTGGGC CGAAGCATCC TGCTCTGAAG 
ATCACTCGTC GCTATGCCTT CGCCCATATC CTAACGGTTC TGCAGTGTGC CACCGTCATT 
GGCTTTTCTT ATTGGGCTTC TGAACTCATC TTGGCCCAGC AGCAGCAGCA TAAGAAGTAC 
CATGGATCCC AGGTCTATGT CACCTTCGCC GTTAGCTTCT ACCTGGTGGC AGGAGCTGGT 
GGAGCCTCAA TCCTGGCCAC GGCAGCCAAC CTCCTGCGCC ACTACCCCAC AGAGGAAGAG 
GAGCAGGCGC TGGAGCTGCT CTCAGAGATG GAAGAGAACG AGCCCTACCC GGCGGAATAT 
GAGGTCATCA ACCAGTTCCA GCCACCCCCT GCTTACACAC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859941.1
CDS	110..574
Translation	MNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP

Target ORF information:

RefSeq Version	XM_017004452.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 127 (TMEM127), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004452.1

ORF Insert Sequence:

ATGAATCCCC AGACAGTGCT GCTCCTGCGG GTCATCGCCG CCTTCTGTTT CCTGGGCATC 
CTGTGTAGTC TCTCCGCTTT CCTTCTGGAT GTCTTTGGGC CGAAGCATCC TGCTCTGAAG 
ATCACTCGTC GCTATGCCTT CGCCCATATC CTAACGGTTC TGCAGTGTGC CACCGTCATT 
GGCTTTTCTT ATTGGGCTTC TGAACTCATC TTGGCCCAGC AGCAGCAGCA TAAGAAGTAC 
CATGGATCCC AGGTCTATGT CACCTTCGCC GTTAGCTTCT ACCTGGTGGC AGGAGCTGGT 
GGAGCCTCAA TCCTGGCCAC GGCAGCCAAC CTCCTGCGCC ACTACCCCAC AGAGGAAGAG 
GAGCAGGCGC TGGAGCTGCT CTCAGAGATG GAAGAGAACG AGCCCTACCC GGCGGAATAT 
GAGGTCATCA ACCAGTTCCA GCCACCCCCT GCTTACACAC CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Homozygous TMEM127-mutations in two patients with bilateral pheochromocytomas.
Clinical genetics(2017 Dec)
Eijkelenkamp K,Olderode-Berends MJW,van der Luijt RB,Robledo M,van Dooren M,Feelders RA,de Vries J,Kerstens MN,Links TP,van der Horst-Schrivers ANA

Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention.
JAMA oncology3(9)1204-1212(2017 Sep)
Bausch B,Schiavi F,Ni Y,Welander J,Patocs A,Ngeow J,Wellner U,Malinoc A,Taschin E,Barbon G,Lanza V,S?derkvist P,Stenman A,Larsson C,Svahn F,Chen JL,Marquard J,Fraenkel M,Walter MA,Peczkowska M,Prejbisz A,Jarzab B,Hasse-Lazar K,Petersenn S,Moeller LC,Meyer A,Reisch N,Trupka A,Brase C,Galiano M,Preuss SF,Kwok P,Lendvai N,Berisha G,Makay ?,Boedeker CC,Weryha G,Racz K,Januszewicz A,Walz MK,Gimm O,Opocher G,Eng C,Neumann HPH,

Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome.
Pathology oncology research : POR22(4)673-9(2016 Oct)
Pat?cs A,Lendvai NK,Butz H,Liko I,Sapi Z,Szucs N,Toth G,Grolmusz VK,Igaz P,Toth M,R?cz K

[Hereditary pheochromocytoma-associated syndromes. Part 1].
Terapevticheskii arkhiv87(9)102-105(2015)
Yukina MY,Troshina EA,Beltsevich DG

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TMEM127 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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