PREP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PREP
Entrez Gene ID	5550
Full Name	prolyl endopeptidase
Synonyms	PE,PEP
General protein information	Preferred Names prolyl endopeptidase Names prolyl endopeptidase dJ355L5.1 (prolyl endopeptidase) post-proline cleaving enzyme prolyl oligopeptidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q21
Summary	The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008].
Disorder MIM:	600400

mRNA and Protein(s)

mRNA	Protein	Name
XM_011535925.2	XP_011534227.1	prolyl endopeptidase isoform X1
NM_002726.5	NP_002717.3	prolyl endopeptidase
NM_002726.4	NP_002717.3	prolyl endopeptidase
XM_005267044.3	XP_005267101.1	prolyl endopeptidase isoform X2
XM_005267044.2	XP_005267101.1	prolyl endopeptidase isoform X2
XM_011535925.3	XP_011534227.1	prolyl endopeptidase isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PREP	XP_518657.2
Rattus norvegicus (Norway rat)	Prep	NP_112614.1
Danio rerio (zebrafish)	prep	NP_001018589.1
Arabidopsis thaliana (thale cress)	AT1G76140	NP_177741.3
Xenopus tropicalis (tropical clawed frog)	prep	NP_989189.1
Drosophila melanogaster (fruit fly)	CG2528	NP_610129.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009172	XP_319935.4
	PREP	XP_001087580.1
Gallus gallus (chicken)	PREP	NP_001006410.1
Arabidopsis thaliana (thale cress)	AT1G20380	NP_173463.1
Oryza sativa (rice)	Os01g0108200	NP_001041787.1
Drosophila melanogaster (fruit fly)	CG5355	NP_609397.2
Homo sapiens (human)	PREP	NP_002717.3
Canis lupus familiaris (dog)	PREP	XP_005627728.1
Bos taurus (cattle)	PREP	NP_777197.1
Mus musculus (house mouse)	Prep	NP_035286.1

Gene Ontology
Bibliography

Related articles in PubMed

Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach.
Van Elzen R, Schoenmakers E, Brandt I, Van Der Veken P, Lambeir AM
Protein engineering, design & selection : PEDS30(3)217-224(2017 Mar)

Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro.
Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm-Helm A, Noortoots A, Anier K, Van Elzen R, G?rard M, Lambeir AM, Ro?ner S, Morawski M, Zharkovsky A
Journal of cell science129(20)3792-3802(2016 10)

Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes.
Szul T, Bratcher PE, Fraser KB, Kong M, Tirouvanziam R, Ingersoll S, Sztul E, Rangarajan S, Blalock JE, Xu X, Gaggar A
American journal of respiratory cell and molecular biology54(3)359-69(2016 Mar)

Prolyl Oligopeptidase Inhibition Attenuates Steatosis in the L02 Human Liver Cell Line.
Zhou D, Li BH, Wang J, Ding YN, Dong Y, Chen YW, Fan JG
PloS one11(10)e0165224(2016)

The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients.
Tenorio-Laranga J, Montoliu C, Urios A, Hernandez-Rabaza V, Ahabrach H, Garc?a-Horsman JA, Felipo V
Journal of neuroinflammation12183(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It was found that human PREP behaves identically to the porcine homolog, displaying a double bell-shaped pH profile and a pH-dependent solvent kinetic isotope effect of the kcat/Km, features that set it apart from the related exopeptidase dipeptidyl peptidase IV (DPP IV).
Title: Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach.

These findings provide evidence for newly-discovered roles for PREP in mechanisms regulating cellular plasticity through NCAM and PSA-NCAM.
Title: Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro.

TLR4 activation releases prolyl endopeptidase containing exosomes from airway epithelial cells.
Title: Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes.

Study shows that the expression of POP increases with hepatocyte steatosis suggesting an important role in hepatocytes steatosis and possibly NAFLD.
Title: Prolyl Oligopeptidase Inhibition Attenuates Steatosis in the L02 Human Liver Cell Line.

This study found that circulating PREP activity was substantially reduced in all cirrhotic patients but those changes did not have evident correlation to hepatic encephalopathy.
Title: The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients.

The following PREP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PREP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23620	NM_002726.5 Latest version!	Homo sapiens prolyl endopeptidase (PREP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu40866	XM_005267044.3 Latest version!	Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu59894	XM_011535925.3 Latest version!	Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu23620	NM_002726.4	Homo sapiens prolyl endopeptidase (PREP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu40866	XM_005267044.2	Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu59894	XM_011535925.2	Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PREP ( NM_002726.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002717.3 Homo sapiens prolyl endopeptidase (PREP), mRNA.

Price & Availability↑

CloneID	OHu23620
Clone ID Related Accession (Same CDS sequence)	NM_002726.5 , NM_002726.4
Accession Version	NM_002726.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	prolyl endopeptidase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314195.1, BC030636.2 and AL133406.14. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_002726.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.929410.1, BC030636.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
TTCTACCCTA GCAAGGATGG TACGAAGATT CCAATGTTCA TTGTGCATAA AAAAGGCATA 
AAATTGGATG GCTCTCATCC AGCTTTCTTA TATGGCTATG GCGGCTTCAA CATATCCATC 
ACACCCAACT ACAGTGTTTC CAGGCTTATT TTTGTGAGAC ACATGGGTGG TATCCTGGCA 
GTGGCCAACA TCAGAGGAGG TGGCGAATAT GGAGAGACGT GGCATAAAGG TGGTATCTTG 
GCCAACAAAC AAAACTGCTT TGATGACTTT CAGTGTGCTG CTGAGTATCT GATCAAGGAA 
GGTTACACAT CTCCCAAGAG GCTGACTATT AATGGAGGTT CAAATGGAGG CCTCTTAGTG 
GCTGCTTGTG CAAATCAGAG ACCTGACCTC TTTGGTTGTG TTATTGCCCA AGTTGGAGTA 
ATGGACATGC TGAAGTTTCA TAAATATACC ATCGGCCATG CTTGGACCAC TGATTATGGG 
TGCTCGGACA GCAAACAACA CTTTGAATGG CTTGTCAAAT ACTCTCCATT GCATAATGTG 
AAGTTACCAG AAGCAGATGA CATCCAGTAC CCGTCCATGC TGCTCCTCAC TGCTGACCAT 
GATGACCGCG TGGTCCCGCT TCACTCCCTG AAGTTCATTG CCACCCTTCA GTACATCGTG 
GGCCGCAGCA GGAAGCAAAG CAACCCCCTG CTTATCCACG TGGACACCAA GGCGGGCCAC 
GGGGCGGGGA AGCCCACAGC CAAAGTGATA GAGGAAGTCT CAGACATGTT TGCGTTCATC 
GCGCGGTGCC TGAACGTCGA CTGGATTCCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002717.3
CDS	192..2324
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP

Target ORF information:

RefSeq Version	NM_002726.5
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002726.5

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
TTCTACCCTA GCAAGGATGG TACGAAGATT CCAATGTTCA TTGTGCATAA AAAAGGCATA 
AAATTGGATG GCTCTCATCC AGCTTTCTTA TATGGCTATG GCGGCTTCAA CATATCCATC 
ACACCCAACT ACAGTGTTTC CAGGCTTATT TTTGTGAGAC ACATGGGTGG TATCCTGGCA 
GTGGCCAACA TCAGAGGAGG TGGCGAATAT GGAGAGACGT GGCATAAAGG TGGTATCTTG 
GCCAACAAAC AAAACTGCTT TGATGACTTT CAGTGTGCTG CTGAGTATCT GATCAAGGAA 
GGTTACACAT CTCCCAAGAG GCTGACTATT AATGGAGGTT CAAATGGAGG CCTCTTAGTG 
GCTGCTTGTG CAAATCAGAG ACCTGACCTC TTTGGTTGTG TTATTGCCCA AGTTGGAGTA 
ATGGACATGC TGAAGTTTCA TAAATATACC ATCGGCCATG CTTGGACCAC TGATTATGGG 
TGCTCGGACA GCAAACAACA CTTTGAATGG CTTGTCAAAT ACTCTCCATT GCATAATGTG 
AAGTTACCAG AAGCAGATGA CATCCAGTAC CCGTCCATGC TGCTCCTCAC TGCTGACCAT 
GATGACCGCG TGGTCCCGCT TCACTCCCTG AAGTTCATTG CCACCCTTCA GTACATCGTG 
GGCCGCAGCA GGAAGCAAAG CAACCCCCTG CTTATCCACG TGGACACCAA GGCGGGCCAC 
GGGGCGGGGA AGCCCACAGC CAAAGTGATA GAGGAAGTCT CAGACATGTT TGCGTTCATC 
GCGCGGTGCC TGAACGTCGA CTGGATTCCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PREP ( NM_002726.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002717.3 Homo sapiens prolyl endopeptidase (PREP), mRNA.

Price & Availability↑

CloneID	OHu23620
Clone ID Related Accession (Same CDS sequence)	NM_002726.5 , NM_002726.4
Accession Version	NM_002726.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	prolyl endopeptidase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA790125.1, AK314195.1, BC030636.2 and AL133406.14. This sequence is a reference standard in the RefSeqGene project. On Jul 3, 2010 this sequence version replaced NM_002726.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.139065.1, SRR1660805.241349.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
TTCTACCCTA GCAAGGATGG TACGAAGATT CCAATGTTCA TTGTGCATAA AAAAGGCATA 
AAATTGGATG GCTCTCATCC AGCTTTCTTA TATGGCTATG GCGGCTTCAA CATATCCATC 
ACACCCAACT ACAGTGTTTC CAGGCTTATT TTTGTGAGAC ACATGGGTGG TATCCTGGCA 
GTGGCCAACA TCAGAGGAGG TGGCGAATAT GGAGAGACGT GGCATAAAGG TGGTATCTTG 
GCCAACAAAC AAAACTGCTT TGATGACTTT CAGTGTGCTG CTGAGTATCT GATCAAGGAA 
GGTTACACAT CTCCCAAGAG GCTGACTATT AATGGAGGTT CAAATGGAGG CCTCTTAGTG 
GCTGCTTGTG CAAATCAGAG ACCTGACCTC TTTGGTTGTG TTATTGCCCA AGTTGGAGTA 
ATGGACATGC TGAAGTTTCA TAAATATACC ATCGGCCATG CTTGGACCAC TGATTATGGG 
TGCTCGGACA GCAAACAACA CTTTGAATGG CTTGTCAAAT ACTCTCCATT GCATAATGTG 
AAGTTACCAG AAGCAGATGA CATCCAGTAC CCGTCCATGC TGCTCCTCAC TGCTGACCAT 
GATGACCGCG TGGTCCCGCT TCACTCCCTG AAGTTCATTG CCACCCTTCA GTACATCGTG 
GGCCGCAGCA GGAAGCAAAG CAACCCCCTG CTTATCCACG TGGACACCAA GGCGGGCCAC 
GGGGCGGGGA AGCCCACAGC CAAAGTGATA GAGGAAGTCT CAGACATGTT TGCGTTCATC 
GCGCGGTGCC TGAACGTCGA CTGGATTCCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002717.3
CDS	234..2366
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP

Target ORF information:

RefSeq Version	NM_002726.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002726.4

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
TTCTACCCTA GCAAGGATGG TACGAAGATT CCAATGTTCA TTGTGCATAA AAAAGGCATA 
AAATTGGATG GCTCTCATCC AGCTTTCTTA TATGGCTATG GCGGCTTCAA CATATCCATC 
ACACCCAACT ACAGTGTTTC CAGGCTTATT TTTGTGAGAC ACATGGGTGG TATCCTGGCA 
GTGGCCAACA TCAGAGGAGG TGGCGAATAT GGAGAGACGT GGCATAAAGG TGGTATCTTG 
GCCAACAAAC AAAACTGCTT TGATGACTTT CAGTGTGCTG CTGAGTATCT GATCAAGGAA 
GGTTACACAT CTCCCAAGAG GCTGACTATT AATGGAGGTT CAAATGGAGG CCTCTTAGTG 
GCTGCTTGTG CAAATCAGAG ACCTGACCTC TTTGGTTGTG TTATTGCCCA AGTTGGAGTA 
ATGGACATGC TGAAGTTTCA TAAATATACC ATCGGCCATG CTTGGACCAC TGATTATGGG 
TGCTCGGACA GCAAACAACA CTTTGAATGG CTTGTCAAAT ACTCTCCATT GCATAATGTG 
AAGTTACCAG AAGCAGATGA CATCCAGTAC CCGTCCATGC TGCTCCTCAC TGCTGACCAT 
GATGACCGCG TGGTCCCGCT TCACTCCCTG AAGTTCATTG CCACCCTTCA GTACATCGTG 
GGCCGCAGCA GGAAGCAAAG CAACCCCCTG CTTATCCACG TGGACACCAA GGCGGGCCAC 
GGGGCGGGGA AGCCCACAGC CAAAGTGATA GAGGAAGTCT CAGACATGTT TGCGTTCATC 
GCGCGGTGCC TGAACGTCGA CTGGATTCCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PREP ( XM_005267044.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267101.1 Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu40866
Clone ID Related Accession (Same CDS sequence)	XM_005267044.3 , XM_005267044.2
Accession Version	XM_005267044.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prolyl endopeptidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005267044.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGCTC 
CCCAAGGGTA CTGAGTCTTC CAGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267101.1
CDS	212..1561
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQLPKGTESSRN

Target ORF information:

RefSeq Version	XM_005267044.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267044.3

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGCTC 
CCCAAGGGTA CTGAGTCTTC CAGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PREP ( XM_005267044.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267101.1 Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu40866
Clone ID Related Accession (Same CDS sequence)	XM_005267044.3 , XM_005267044.2
Accession Version	XM_005267044.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	prolyl endopeptidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267044.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGCTC 
CCCAAGGGTA CTGAGTCTTC CAGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267101.1
CDS	234..1583
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQLPKGTESSRN

Target ORF information:

RefSeq Version	XM_005267044.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267044.2

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGCTC 
CCCAAGGGTA CTGAGTCTTC CAGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PREP ( XM_011535925.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534227.1 Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59894
Clone ID Related Accession (Same CDS sequence)	XM_011535925.2 , XM_011535925.3
Accession Version	XM_011535925.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	prolyl endopeptidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535925.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
CCTCGTTTTT TAAAAACTGA AGGTTTGAAG CAACCTTGTG TTGAACAAGT CTGTTACCAC 
CATTTTCCCA ACAGCATGTG CTCAGTTCGT GTCTGTCACA TTTTGATAAT TCTCACAATG 
TTTCAAGCTT TTTCATTATT ACATCACAGT GAGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534227.1
CDS	234..1712
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIPRFLKTEGLKQPCVEQVCYHHFPNSMCSVRVCHILIILTMFQAFSLLHHSEL

Target ORF information:

RefSeq Version	XM_011535925.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535925.2

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
CCTCGTTTTT TAAAAACTGA AGGTTTGAAG CAACCTTGTG TTGAACAAGT CTGTTACCAC 
CATTTTCCCA ACAGCATGTG CTCAGTTCGT GTCTGTCACA TTTTGATAAT TCTCACAATG 
TTTCAAGCTT TTTCATTATT ACATCACAGT GAGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PREP ( XM_011535925.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534227.1 Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.

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CloneID	OHu59894
Clone ID Related Accession (Same CDS sequence)	XM_011535925.2 , XM_011535925.3
Accession Version	XM_011535925.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prolyl endopeptidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011535925.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
CCTCGTTTTT TAAAAACTGA AGGTTTGAAG CAACCTTGTG TTGAACAAGT CTGTTACCAC 
CATTTTCCCA ACAGCATGTG CTCAGTTCGT GTCTGTCACA TTTTGATAAT TCTCACAATG 
TTTCAAGCTT TTTCATTATT ACATCACAGT GAGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534227.1
CDS	212..1690
Translation	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIPRFLKTEGLKQPCVEQVCYHHFPNSMCSVRVCHILIILTMFQAFSLLHHSEL

Target ORF information:

RefSeq Version	XM_011535925.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl endopeptidase (PREP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535925.3

ORF Insert Sequence:

ATGCTGTCCC TTCAGTACCC CGACGTGTAC CGCGACGAGA CCGCCGTACA GGATTATCAT 
GGTCATAAAA TTTGTGACCC TTACGCCTGG CTTGAAGACC CCGACAGTGA ACAGACTAAG 
GCCTTTGTGG AGGCCCAGAA TAAGATTACT GTGCCATTTC TTGAGCAGTG TCCCATCAGA 
GGTTTATACA AAGAGAGAAT GACTGAACTA TATGATTATC CCAAGTATAG TTGCCACTTC 
AAGAAAGGAA AACGGTATTT TTATTTTTAC AATACAGGTT TGCAGAACCA GCGAGTATTA 
TATGTACAGG ATTCCTTAGA GGGTGAGGCC AGAGTGTTCC TGGACCCCAA CATACTGTCT 
GACGATGGCA CAGTGGCACT CCGAGGTTAT GCGTTCAGCG AAGATGGTGA ATATTTTGCC 
TATGGTCTGA GTGCCAGTGG CTCAGACTGG GTGACAATCA AGTTCATGAA AGTTGATGGT 
GCCAAAGAGC TTCCAGATGT GCTTGAAAGA GTCAAGTTCA GCTGTATGGC CTGGACCCAT 
GATGGGAAGG GAATGTTCTA CAACTCATAC CCTCAACAGG ATGGAAAAAG TGATGGCACA 
GAGACATCTA CCAATCTCCA CCAAAAGCTC TACTACCATG TCTTGGGAAC CGATCAGTCA 
GAAGATATTT TGTGTGCTGA GTTTCCTGAT GAACCTAAAT GGATGGGTGG AGCTGAGTTA 
TCTGATGATG GCCGCTATGT CTTGTTATCA ATAAGGGAAG GATGTGATCC AGTAAACCGA 
CTCTGGTACT GTGACCTACA GCAGGAATCC AGTGGCATCG CGGGAATCCT GAAGTGGGTA 
AAACTGATTG ACAACTTTGA AGGGGAATAT GACTACGTGA CCAATGAGGG GACGGTGTTC 
ACATTCAAGA CGAATCGCCA GTCTCCCAAC TATCGCGTGA TCAACATTGA CTTCAGGGAT 
CCTGAAGAGT CTAAGTGGAA AGTACTTGTT CCTGAGCATG AGAAAGATGT CTTAGAATGG 
ATAGCTTGTG TCAGGTCCAA CTTCTTGGTC TTATGCTACC TCCATGACGT CAAGAACATT 
CTGCAGCTCC ATGACCTGAC TACTGGTGCT CTCCTTAAGA CCTTCCCGCT CGATGTCGGC 
AGCATTGTAG GGTACAGCGG TCAGAAGAAG GACACTGAAA TCTTCTATCA GTTTACTTCC 
TTTTTATCTC CAGGTATCAT TTATCACTGT GATCTTACCA AAGAGGAGCT GGAGCCAAGA 
GTTTTCCGAG AGGTGACCGT AAAAGGAATT GATGCTTCTG ATTACCAGAC AGTCCAGATT 
CCTCGTTTTT TAAAAACTGA AGGTTTGAAG CAACCTTGTG TTGAACAAGT CTGTTACCAC 
CATTTTCCCA ACAGCATGTG CTCAGTTCGT GTCTGTCACA TTTTGATAAT TCTCACAATG 
TTTCAAGCTT TTTCATTATT ACATCACAGT GAGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach.
Protein engineering, design & selection : PEDS30(3)217-224(2017 Mar)
Van Elzen R,Schoenmakers E,Brandt I,Van Der Veken P,Lambeir AM

Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro.
Journal of cell science129(20)3792-3802(2016 10)
Jaako K,Waniek A,Parik K,Klimaviciusa L,Aonurm-Helm A,Noortoots A,Anier K,Van Elzen R,G?rard M,Lambeir AM,Ro?ner S,Morawski M,Zharkovsky A

Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes.
American journal of respiratory cell and molecular biology54(3)359-69(2016 Mar)
Szul T,Bratcher PE,Fraser KB,Kong M,Tirouvanziam R,Ingersoll S,Sztul E,Rangarajan S,Blalock JE,Xu X,Gaggar A

Prolyl Oligopeptidase Inhibition Attenuates Steatosis in the L02 Human Liver Cell Line.
PloS one11(10)e0165224(2016)
Zhou D,Li BH,Wang J,Ding YN,Dong Y,Chen YW,Fan JG

The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients.
Journal of neuroinflammation12183(2015 Sep)
Tenorio-Laranga J,Montoliu C,Urios A,Hernandez-Rabaza V,Ahabrach H,Garc?a-Horsman JA,Felipo V

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PREP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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