RASD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RASD1
Entrez Gene ID	51655
Full Name	ras related dexamethasone induced 1
Synonyms	AGS1,DEXRAS1,MGC:26290
General protein information	Preferred Names ras related dexamethasone induced 1 Names dexamethasone-induced Ras-related protein 1 RAS, dexamethasone-induced 1 activator of G-protein signaling 1 ras-related protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p11.2
Summary	This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011].
Disorder MIM:	605550

mRNA and Protein(s)

mRNA	Protein	Name
NM_016084.4	NP_057168.1	dexamethasone-induced Ras-related protein 1 isoform 1 proprotein
NM_016084.5	NP_057168.1	dexamethasone-induced Ras-related protein 1 isoform 1 proprotein
NM_001199989.1	NP_001186918.1	dexamethasone-induced Ras-related protein 1 isoform 2
NM_001199989.2	NP_001186918.1	dexamethasone-induced Ras-related protein 1 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RASD1	XP_523573.2
Rattus norvegicus (Norway rat)	Rasd1	NP_001257883.1
Xenopus tropicalis (tropical clawed frog)	rasd1	NP_001072408.1
	RASD1	XP_001090082.1
Gallus gallus (chicken)	RASD1	NP_001038101.1
Bos taurus (cattle)	RASD1	NP_001193190.1
Homo sapiens (human)	RASD1	NP_057168.1
Mus musculus (house mouse)	Rasd1	NP_033052.1
Canis lupus familiaris (dog)	RASD1	XP_546661.2
Danio rerio (zebrafish)	rasd1	NP_956826.1
Drosophila melanogaster (fruit fly)	CG8641	NP_648073.1

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway.
Gao S, Jin L, Liu G, Wang P, Sun Z, Cao Y, Shi H, Liu X, Shi Q, Zhou X, Yu R
Scientific reports7(1)3202(2017 Jun)

PKA-mediated phosphorylation of Dexras1 suppresses iron trafficking by inhibiting S-nitrosylation.
Chen Y, Mathias L, Falero-Perez JM, Kim SF
FEBS letters589(20 Pt B)3212-9(2015 Oct)

The Roles of Rasd1 small G proteins and leptin in the activation of TRPC4 transient receptor potential channels.
Wie J, Kim BJ, Myeong J, Ha K, Jeong SJ, Yang D, Kim E, Jeon JH, So I
Channels (Austin, Tex.)9(4)186-95(2015)

Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro.
Liu XJ, Li YQ, Chen QY, Xiao SJ, Zeng SE
Asian Pacific journal of cancer prevention : APJCP15(6)2835-9(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that protein kinase A (PKA) phosphorylates only serine-253 amino acid on activator of G-protein signaling 1 protein Dexras1 (RASD1).
Title: PKA-mediated phosphorylation of Dexras1 suppresses iron trafficking by inhibiting S-nitrosylation.

Studies indicate potential roles for Rasd1 small G protein and leptin in TRPC4 cation channel activation.
Title: The Roles of Rasd1 small G proteins and leptin in the activation of TRPC4 transient receptor potential channels.

Loss of RASD1 is associated with prostate cancer.
Title: Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro.

Rasd1 modulates endogenous renin gene expression by interacting with Ear2.
Title: Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription.

Study showed that Rasd1 and NonO interact at the CRE-site of specific target genes.
Title: Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.

The following RASD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RASD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17790	NM_016084.5 Latest version!	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$216.30 $309.00
OHu06169	NM_001199989.2 Latest version!	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu17790	NM_016084.4	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$216.30 $309.00
OHu06169	NM_001199989.1	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RASD1 ( NM_016084.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057168.1 Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17790
Clone ID Related Accession (Same CDS sequence)	NM_016084.4 , NM_016084.5
Accession Version	NM_016084.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	dexamethasone-induced Ras-related protein 1 isoform 1 proprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312796.1, BC018041.1 and BC042688.1. This sequence is a reference standard in the RefSeqGene project. On Jan 6, 2011 this sequence version replaced NM_016084.3. Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042688.1, BC018041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGGAGA CGTTTTCATC 
CTGGTGTTCA GTCTGGACAA CCGCGACTCC TTCGAGGAGG TGCAGCGGCT CAGGCAGCAG 
ATCCTCGACA CCAAGTCTTG CCTCAAGAAC AAAACCAAGG AGAACGTGGA CGTGCCCCTG 
GTCATCTGCG GCAACAAGGG TGACCGCGAC TTCTACCGCG AGGTGGACCA GCGCGAGATC 
GAGCAGCTGG TGGGCGACGA CCCCCAGCGC TGCGCCTACT TCGAGATCTC GGCCAAGAAG 
AACAGCAGCC TGGACCAGAT GTTCCGCGCG CTCTTCGCCA TGGCCAAGCT GCCCAGCGAG 
ATGAGCCCAG ACCTGCACCG CAAGGTCTCG GTGCAGTACT GCGACGTGCT GCACAAGAAG 
GCGCTGCGGA ACAAGAAGCT GCTGCGGGCC GGCAGCGGCG GCGGCGGCGG CGACCCGGGC 
GACGCCTTTG GCATCGTGGC ACCCTTCGCG CGCCGGCCCA GCGTACACAG CGACCTCATG 
TACATCCGCG AGAAGGCCAG CGCCGGCAGC CAGGCCAAGG ACAAGGAGCG CTGCGTCATC 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057168.1
CDS	215..1060
Translation	MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS

Target ORF information:

RefSeq Version	NM_016084.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016084.4

ORF Insert Sequence:

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGGAGA CGTTTTCATC 
CTGGTGTTCA GTCTGGACAA CCGCGACTCC TTCGAGGAGG TGCAGCGGCT CAGGCAGCAG 
ATCCTCGACA CCAAGTCTTG CCTCAAGAAC AAAACCAAGG AGAACGTGGA CGTGCCCCTG 
GTCATCTGCG GCAACAAGGG TGACCGCGAC TTCTACCGCG AGGTGGACCA GCGCGAGATC 
GAGCAGCTGG TGGGCGACGA CCCCCAGCGC TGCGCCTACT TCGAGATCTC GGCCAAGAAG 
AACAGCAGCC TGGACCAGAT GTTCCGCGCG CTCTTCGCCA TGGCCAAGCT GCCCAGCGAG 
ATGAGCCCAG ACCTGCACCG CAAGGTCTCG GTGCAGTACT GCGACGTGCT GCACAAGAAG 
GCGCTGCGGA ACAAGAAGCT GCTGCGGGCC GGCAGCGGCG GCGGCGGCGG CGACCCGGGC 
GACGCCTTTG GCATCGTGGC ACCCTTCGCG CGCCGGCCCA GCGTACACAG CGACCTCATG 
TACATCCGCG AGAAGGCCAG CGCCGGCAGC CAGGCCAAGG ACAAGGAGCG CTGCGTCATC 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASD1 ( NM_016084.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057168.1 Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17790
Clone ID Related Accession (Same CDS sequence)	NM_016084.4 , NM_016084.5
Accession Version	NM_016084.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	dexamethasone-induced Ras-related protein 1 isoform 1 proprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073621.21. On Nov 23, 2018 this sequence version replaced NM_016084.4. Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.722759.1, SRR3476690.810915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000225688.4/ ENSP00000225688.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGGAGA CGTTTTCATC 
CTGGTGTTCA GTCTGGACAA CCGCGACTCC TTCGAGGAGG TGCAGCGGCT CAGGCAGCAG 
ATCCTCGACA CCAAGTCTTG CCTCAAGAAC AAAACCAAGG AGAACGTGGA CGTGCCCCTG 
GTCATCTGCG GCAACAAGGG TGACCGCGAC TTCTACCGCG AGGTGGACCA GCGCGAGATC 
GAGCAGCTGG TGGGCGACGA CCCCCAGCGC TGCGCCTACT TCGAGATCTC GGCCAAGAAG 
AACAGCAGCC TGGACCAGAT GTTCCGCGCG CTCTTCGCCA TGGCCAAGCT GCCCAGCGAG 
ATGAGCCCAG ACCTGCACCG CAAGGTCTCG GTGCAGTACT GCGACGTGCT GCACAAGAAG 
GCGCTGCGGA ACAAGAAGCT GCTGCGGGCC GGCAGCGGCG GCGGCGGCGG CGACCCGGGC 
GACGCCTTTG GCATCGTGGC ACCCTTCGCG CGCCGGCCCA GCGTACACAG CGACCTCATG 
TACATCCGCG AGAAGGCCAG CGCCGGCAGC CAGGCCAAGG ACAAGGAGCG CTGCGTCATC 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057168.1
CDS	215..1060
Translation	MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS

Target ORF information:

RefSeq Version	NM_016084.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016084.5

ORF Insert Sequence:

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGGAGA CGTTTTCATC 
CTGGTGTTCA GTCTGGACAA CCGCGACTCC TTCGAGGAGG TGCAGCGGCT CAGGCAGCAG 
ATCCTCGACA CCAAGTCTTG CCTCAAGAAC AAAACCAAGG AGAACGTGGA CGTGCCCCTG 
GTCATCTGCG GCAACAAGGG TGACCGCGAC TTCTACCGCG AGGTGGACCA GCGCGAGATC 
GAGCAGCTGG TGGGCGACGA CCCCCAGCGC TGCGCCTACT TCGAGATCTC GGCCAAGAAG 
AACAGCAGCC TGGACCAGAT GTTCCGCGCG CTCTTCGCCA TGGCCAAGCT GCCCAGCGAG 
ATGAGCCCAG ACCTGCACCG CAAGGTCTCG GTGCAGTACT GCGACGTGCT GCACAAGAAG 
GCGCTGCGGA ACAAGAAGCT GCTGCGGGCC GGCAGCGGCG GCGGCGGCGG CGACCCGGGC 
GACGCCTTTG GCATCGTGGC ACCCTTCGCG CGCCGGCCCA GCGTACACAG CGACCTCATG 
TACATCCGCG AGAAGGCCAG CGCCGGCAGC CAGGCCAAGG ACAAGGAGCG CTGCGTCATC 
AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASD1 ( NM_001199989.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186918.1 Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06169
Clone ID Related Accession (Same CDS sequence)	NM_001199989.1 , NM_001199989.2
Accession Version	NM_001199989.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	dexamethasone-induced Ras-related protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK294073.1, BC018041.1 and BC042688.1. Transcript Variant: This variant (2) has an alternate splice site in the CDS that results in a frame-shift compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294073.1, DC311138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END##

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGATCC TCGACACCAA 
GTCTTGCCTC AAGAACAAAA CCAAGGAGAA CGTGGACGTG CCCCTGGTCA TCTGCGGCAA 
CAAGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186918.1
CDS	215..583
Translation	MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTDPRHQVLPQEQNQGERGRAPGHLRQQG

Target ORF information:

RefSeq Version	NM_001199989.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199989.1

ORF Insert Sequence:

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGATCC TCGACACCAA 
GTCTTGCCTC AAGAACAAAA CCAAGGAGAA CGTGGACGTG CCCCTGGTCA TCTGCGGCAA 
CAAGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASD1 ( NM_001199989.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186918.1 Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06169
Clone ID Related Accession (Same CDS sequence)	NM_001199989.1 , NM_001199989.2
Accession Version	NM_001199989.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	dexamethasone-induced Ras-related protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073621.21. On May 31, 2019 this sequence version replaced NM_001199989.1. Transcript Variant: This variant (2) has an alternate splice site in the CDS that results in a frame-shift compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294073.1, DC311138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END##

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGATCC TCGACACCAA 
GTCTTGCCTC AAGAACAAAA CCAAGGAGAA CGTGGACGTG CCCCTGGTCA TCTGCGGCAA 
CAAGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186918.1
CDS	215..583
Translation	MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTDPRHQVLPQEQNQGERGRAPGHLRQQG

Target ORF information:

RefSeq Version	NM_001199989.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ras related dexamethasone induced 1 (RASD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199989.2

ORF Insert Sequence:

ATGAAACTGG CCGCGATGAT CAAGAAGATG TGCCCGAGCG ACTCGGAGCT GAGTATCCCG 
GCCAAGAACT GCTATCGCAT GGTCATCCTC GGCTCGTCCA AGGTGGGCAA GACGGCCATC 
GTGTCGCGCT TCCTCACCGG CCGCTTCGAG GACGCCTACA CGCCTACCAT CGAGGACTTC 
CACCGCAAGT TCTACTCCAT CCGCGGCGAG GTCTACCAGC TCGACATCCT CGACACGTCC 
GGCAACCACC CGTTCCCCGC CATGCGGCGC CTCTCCATCC TCACAGATCC TCGACACCAA 
GTCTTGCCTC AAGAACAAAA CCAAGGAGAA CGTGGACGTG CCCCTGGTCA TCTGCGGCAA 
CAAGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway.
Scientific reports7(1)3202(2017 Jun)
Gao S,Jin L,Liu G,Wang P,Sun Z,Cao Y,Shi H,Liu X,Shi Q,Zhou X,Yu R

PKA-mediated phosphorylation of Dexras1 suppresses iron trafficking by inhibiting S-nitrosylation.
FEBS letters589(20 Pt B)3212-9(2015 Oct)
Chen Y,Mathias L,Falero-Perez JM,Kim SF

The Roles of Rasd1 small G proteins and leptin in the activation of TRPC4 transient receptor potential channels.
Channels (Austin, Tex.)9(4)186-95(2015)
Wie J,Kim BJ,Myeong J,Ha K,Jeong SJ,Yang D,Kim E,Jeon JH,So I

Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro.
Asian Pacific journal of cancer prevention : APJCP15(6)2835-9(2014)
Liu XJ,Li YQ,Chen QY,Xiao SJ,Zeng SE

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RASD1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報