Gene Symbol | PDGFRL |
Entrez Gene ID | 5157 |
Full Name | platelet derived growth factor receptor like |
Synonyms | PDGRL,PRLTS |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Hepatocellular cancer, somatic, 114550 (3); Colorectal cancer, somatic, 114500 (3) |