TAS2R13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R13
Entrez Gene ID	50838
Full Name	taste 2 receptor member 13
Synonyms	T2R13,TRB3
General protein information	Preferred Names taste 2 receptor member 13 Names taste receptor type 2 member 13 taste receptor, family B, member 3 taste receptor, type 2, member 13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Summary	This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008].
Disorder MIM:	604792

mRNA and Protein(s)

mRNA	Protein	Name
NM_023920.2	NP_076409.1	taste receptor type 2 member 13

Pathways from BioSystems

Homologies

Homo sapiens (human)	TAS2R13	NP_076409.1
Mus musculus (house mouse)	Tas2r121	NP_996907.1
Rattus norvegicus (Norway rat)	Tas2r121	NP_076487.1
Pan troglodytes (chimpanzee)	TAS2R13	NP_001009141.1
	TAS2R13	NP_001074236.1
Xenopus tropicalis (tropical clawed frog)	t2r8	NP_001165471.1

Gene Ontology
Bibliography

Related articles in PubMed

Polymorphisms in TRPV1 and TAS2Rs associate with sensations from sampled ethanol.
Allen AL, McGeary JE, Hayes JE
Alcoholism, clinical and experimental research38(10)2550-60(2014 Oct)

G protein-coupled receptors participate in cytokinesis.
Zhang X, Bedigian AV, Wang W, Eggert US
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)

Variation in the gene TAS2R13 is associated with differences in alcohol consumption in patients with head and neck cancer.
Dotson CD, Wallace MR, Bartoshuk LM, Logan HL
Chemical senses37(8)737-44(2012 Oct)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Genetic variation in TRPV1 and TAS2Rs influence sensations from sampled EtOH and may potentially influence how individuals initially respond to alcoholic beverages.
Title: Polymorphisms in TRPV1 and TAS2Rs associate with sensations from sampled ethanol.

It found a single nucleotide polymorphism (SNP) located within the TAS2R13 gene, which showed a significant association with measures of alcohol consumption assessed via the Alcohol Use Disorders Identification Test (AUDIT).
Title: Variation in the gene TAS2R13 is associated with differences in alcohol consumption in patients with head and neck cancer.

The following TAS2R13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30982	NM_023920.2 Latest version!	Homo sapiens taste 2 receptor member 13 (TAS2R13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R13 ( NM_023920.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_076409.1 Homo sapiens taste 2 receptor member 13 (TAS2R13), mRNA.

Price & Availability↑

CloneID	OHu30982
Clone ID Related Accession (Same CDS sequence)	NM_023920.2
Accession Version	NM_023920.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095518.1 and AC006518.17. On Jun 17, 2005 this sequence version replaced NM_023920.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC095518.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000390677.2/ ENSP00000375095.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGAAAGTG CCCTGCCGAG TATCTTCACT CTTGTAATAA TTGCAGAATT CATAATTGGG 
AATTTGAGCA ATGGATTTAT AGTACTGATC AACTGCATTG ACTGGGTCAG TAAAAGAGAG 
CTGTCCTCAG TCGATAAACT CCTCATTATC TTGGCAATCT CCAGAATTGG GCTGATCTGG 
GAAATATTAG TAAGTTGGTT TTTAGCTCTG CATTATCTAG CCATATTTGT GTCTGGAACA 
GGATTAAGAA TTATGATTTT TAGCTGGATA GTTTCTAATC ACTTCAATCT CTGGCTTGCT 
ACAATCTTCA GCATCTTTTA TTTGCTCAAA ATAGCGAGTT TCTCTAGCCC TGCTTTTCTC 
TATTTGAAGT GGAGAGTAAA CAAAGTGATT CTGATGATAC TGCTAGGAAC CTTGGTCTTC 
TTATTTTTAA ATCTGATACA AATAAACATG CATATAAAAG ACTGGCTGGA CCGATATGAA 
AGAAACACAA CTTGGAATTT CAGTATGAGT GACTTTGAAA CATTTTCAGT GTCGGTCAAA 
TTCACTATGA CTATGTTCAG TCTAACACCA TTTACTGTGG CCTTCATCTC TTTTCTCCTG 
TTAATTTTCT CCCTGCAGAA ACATCTCCAG AAAATGCAAC TCAATTACAA AGGACACAGA 
GACCCCAGGA CCAAGGTCCA TACAAATGCC TTGAAAATTG TGATCTCATT CCTTTTATTC 
TATGCTAGTT TCTTTCTATG TGTTCTCATA TCATGGATTT CTGAGCTGTA TCAGAACACA 
GTGATCTACA TGCTTTGTGA GACGATTGGA GTCTTCTCTC CTTCAAGCCA CTCCTTTCTT 
CTGATTCTAG GAAACGCTAA GTTAAGACAG GCCTTTCTTT TGGTGGCAGC TAAGGTATGG 
GCTAAACGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076409.1
CDS	265..1176
Translation	MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFLNLIQINMHIKDWLDRYERNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVISFLLFYASFFLCVLISWISELYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFLLVAAKVWAKR

Target ORF information:

RefSeq Version	NM_023920.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 13 (TAS2R13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023920.2

ORF Insert Sequence:

ATGGAAAGTG CCCTGCCGAG TATCTTCACT CTTGTAATAA TTGCAGAATT CATAATTGGG 
AATTTGAGCA ATGGATTTAT AGTACTGATC AACTGCATTG ACTGGGTCAG TAAAAGAGAG 
CTGTCCTCAG TCGATAAACT CCTCATTATC TTGGCAATCT CCAGAATTGG GCTGATCTGG 
GAAATATTAG TAAGTTGGTT TTTAGCTCTG CATTATCTAG CCATATTTGT GTCTGGAACA 
GGATTAAGAA TTATGATTTT TAGCTGGATA GTTTCTAATC ACTTCAATCT CTGGCTTGCT 
ACAATCTTCA GCATCTTTTA TTTGCTCAAA ATAGCGAGTT TCTCTAGCCC TGCTTTTCTC 
TATTTGAAGT GGAGAGTAAA CAAAGTGATT CTGATGATAC TGCTAGGAAC CTTGGTCTTC 
TTATTTTTAA ATCTGATACA AATAAACATG CATATAAAAG ACTGGCTGGA CCGATATGAA 
AGAAACACAA CTTGGAATTT CAGTATGAGT GACTTTGAAA CATTTTCAGT GTCGGTCAAA 
TTCACTATGA CTATGTTCAG TCTAACACCA TTTACTGTGG CCTTCATCTC TTTTCTCCTG 
TTAATTTTCT CCCTGCAGAA ACATCTCCAG AAAATGCAAC TCAATTACAA AGGACACAGA 
GACCCCAGGA CCAAGGTCCA TACAAATGCC TTGAAAATTG TGATCTCATT CCTTTTATTC 
TATGCTAGTT TCTTTCTATG TGTTCTCATA TCATGGATTT CTGAGCTGTA TCAGAACACA 
GTGATCTACA TGCTTTGTGA GACGATTGGA GTCTTCTCTC CTTCAAGCCA CTCCTTTCTT 
CTGATTCTAG GAAACGCTAA GTTAAGACAG GCCTTTCTTT TGGTGGCAGC TAAGGTATGG 
GCTAAACGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Polymorphisms in TRPV1 and TAS2Rs associate with sensations from sampled ethanol.
Alcoholism, clinical and experimental research38(10)2550-60(2014 Oct)
Allen AL,McGeary JE,Hayes JE

G protein-coupled receptors participate in cytokinesis.
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)
Zhang X,Bedigian AV,Wang W,Eggert US

Variation in the gene TAS2R13 is associated with differences in alcohol consumption in patients with head and neck cancer.
Chemical senses37(8)737-44(2012 Oct)
Dotson CD,Wallace MR,Bartoshuk LM,Logan HL

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

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TAS2R13 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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