Tas2r121 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tas2r121
Entrez Gene ID	78983
Full Name	taste receptor, type 2, member 121
Synonyms	T2R7,Tas2r13,Tas2r7
General protein information	Preferred Names taste receptor, type 2, member 121 Names taste receptor type 2 member 13 T2R13 taste receptor T2R7 taste receptor type 2 member 7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42
Summary	member of a family of mammalian taste receptors that couple with the G protein alpha subunit gustducin; may play a role in bitter taste perception [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_023997.1	NP_076487.1	taste receptor type 2 member 13

Pathways from BioSystems

Homologies

Homo sapiens (human)	TAS2R13	NP_076409.1
Mus musculus (house mouse)	Tas2r121	NP_996907.1
Rattus norvegicus (Norway rat)	Tas2r121	NP_076487.1
Pan troglodytes (chimpanzee)	TAS2R13	NP_001009141.1
	TAS2R13	NP_001074236.1
Xenopus tropicalis (tropical clawed frog)	t2r8	NP_001165471.1

Gene Ontology
Bibliography

Related articles in PubMed

G protein-coupled receptors participate in cytokinesis.
Zhang X, Bedigian AV, Wang W, Eggert US
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ
Cell112(3)293-301(2003 Feb)

Receptors for bitter and sweet taste.
Montmayeur JP, Matsunami H
Current opinion in neurobiology12(4)366-71(2002 Aug)

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.
Wu SV, Rozengurt N, Yang M, Young SH, Sinnett-Smith J, Rozengurt E
Proceedings of the National Academy of Sciences of the United States of America99(4)2392-7(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tas2r121 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tas2r121 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42471	NM_023997.1 Latest version!	Rattus norvegicus taste receptor, type 2, member 121 (Tas2r121), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tas2r121 ( NM_023997.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_076487.1 Rattus norvegicus taste receptor, type 2, member 121 (Tas2r121), mRNA.

Price & Availability↑

CloneID	ORa42471
Clone ID Related Accession (Same CDS sequence)	NM_023997.1
Accession Version	NM_023997.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	taste receptor type 2 member 13
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF227144.1. ##Evidence-Data-START## Transcript exon combination :: AF227144.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGAAGCA GCCTGTATGA TATCTTAACT ATTGTCATGA TTGCAGAGTT TATATTCGGA 
AATGTGACCA ATGGATTCAT AGTGCTGACA AACTGTATTG CTTGGCTCAG TAAAAGAACT 
CTTTCTTTCA TTGGTTGGAT CCAGCTTTTC TTGGCCATTT CCAGAGTGGT TTTGATATGG 
GAAATGTTAC TAGCATGGCT GAAATATATG AAGTATTCAT TTTCATATTT GGCTGGCACA 
GAATTAAGGG TTATGATGTT GACCTGGGTA GTTTCCAATC ACTTTAGTCT CTGGCTTGCC 
ACCATTCTAA GCATCTTTTA TTTGCTCAAA ATAGCTAGTT TCTCCAGACC TGTTTTCCTG 
TATCTGAAGT GGAGAGTAAA AAAAGTGCTC CTGCTGATTC TTCTCGGAAA TTTAATCTTC 
CTGATGTTCA ATATATTACA AATCAACACT CACATAGAAG ACTGGATGGA TCAATATAAG 
AGAAATATAA CGTGGGATTC CAGAGTGAAT GAATTTGTGG GGTTTTCAAA TCTGGTTTTA 
TTGGAGATGA TTATGTTCTC TGTAACACCA TTCACCGTGG CTCTGGTCTC CTTCATCCTG 
TTAATCTTCT CTTTATGGAA ACATCTCCAG AAGATGCATC TCAGTTCCAG AGGGGAACGA 
GACCCTAGCA CAAAAGCCCA TGTGAATGCC CTGAGAATTA TGGTCTCCTT CCTCTTACTC 
TATGCCACTT ACTTCATATC CTTTTTTATA TCATTAATTC CTATGGCACA TAAAAAAGGA 
CTAGATCTTA TGTTTAGCCT AACTGTTGGA CTTTTCTACC CTTCAAGCCA CTCATTTATC 
TTGATTTTGG GACATTCTAA TCTAAGGCAT TCCAGTTGTC TGGTGATAAC CTATCTGAGA 
TGTAAGGAAA AGGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076487.1
CDS	1..918
Translation	MGSSLYDILTIVMIAEFIFGNVTNGFIVLTNCIAWLSKRTLSFIGWIQLFLAISRVVLIWEMLLAWLKYMKYSFSYLAGTELRVMMLTWVVSNHFSLWLATILSIFYLLKIASFSRPVFLYLKWRVKKVLLLILLGNLIFLMFNILQINTHIEDWMDQYKRNITWDSRVNEFVGFSNLVLLEMIMFSVTPFTVALVSFILLIFSLWKHLQKMHLSSRGERDPSTKAHVNALRIMVSFLLLYATYFISFFISLIPMAHKKGLDLMFSLTVGLFYPSSHSFILILGHSNLRHSSCLVITYLRCKEKD

Target ORF information:

RefSeq Version	NM_023997.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus taste receptor, type 2, member 121 (Tas2r121), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023997.1

ORF Insert Sequence:

ATGGGAAGCA GCCTGTATGA TATCTTAACT ATTGTCATGA TTGCAGAGTT TATATTCGGA 
AATGTGACCA ATGGATTCAT AGTGCTGACA AACTGTATTG CTTGGCTCAG TAAAAGAACT 
CTTTCTTTCA TTGGTTGGAT CCAGCTTTTC TTGGCCATTT CCAGAGTGGT TTTGATATGG 
GAAATGTTAC TAGCATGGCT GAAATATATG AAGTATTCAT TTTCATATTT GGCTGGCACA 
GAATTAAGGG TTATGATGTT GACCTGGGTA GTTTCCAATC ACTTTAGTCT CTGGCTTGCC 
ACCATTCTAA GCATCTTTTA TTTGCTCAAA ATAGCTAGTT TCTCCAGACC TGTTTTCCTG 
TATCTGAAGT GGAGAGTAAA AAAAGTGCTC CTGCTGATTC TTCTCGGAAA TTTAATCTTC 
CTGATGTTCA ATATATTACA AATCAACACT CACATAGAAG ACTGGATGGA TCAATATAAG 
AGAAATATAA CGTGGGATTC CAGAGTGAAT GAATTTGTGG GGTTTTCAAA TCTGGTTTTA 
TTGGAGATGA TTATGTTCTC TGTAACACCA TTCACCGTGG CTCTGGTCTC CTTCATCCTG 
TTAATCTTCT CTTTATGGAA ACATCTCCAG AAGATGCATC TCAGTTCCAG AGGGGAACGA 
GACCCTAGCA CAAAAGCCCA TGTGAATGCC CTGAGAATTA TGGTCTCCTT CCTCTTACTC 
TATGCCACTT ACTTCATATC CTTTTTTATA TCATTAATTC CTATGGCACA TAAAAAAGGA 
CTAGATCTTA TGTTTAGCCT AACTGTTGGA CTTTTCTACC CTTCAAGCCA CTCATTTATC 
TTGATTTTGG GACATTCTAA TCTAAGGCAT TCCAGTTGTC TGGTGATAAC CTATCTGAGA 
TGTAAGGAAA AGGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

G protein-coupled receptors participate in cytokinesis.
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)
Zhang X,Bedigian AV,Wang W,Eggert US

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Cell112(3)293-301(2003 Feb)
Zhang Y,Hoon MA,Chandrashekar J,Mueller KL,Cook B,Wu D,Zuker CS,Ryba NJ

Receptors for bitter and sweet taste.
Current opinion in neurobiology12(4)366-71(2002 Aug)
Montmayeur JP,Matsunami H

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells.
Proceedings of the National Academy of Sciences of the United States of America99(4)2392-7(2002 Feb)
Wu SV,Rozengurt N,Yang M,Young SH,Sinnett-Smith J,Rozengurt E