OMP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OMP
Entrez Gene ID	4975
Full Name	olfactory marker protein
General protein information	Preferred Names olfactory marker protein Names olfactory marker protein olfactory neuronal-specific protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.5
Summary	Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008].
Disorder MIM:	164340

mRNA and Protein(s)

mRNA	Protein	Name
NM_006189.1	NP_006180.1	olfactory marker protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	OMP	NP_006180.1
Pan troglodytes (chimpanzee)	OMP	XP_001175038.1
	OMP	XP_001088923.1
Canis lupus familiaris (dog)	OMP	XP_005633517.1
Xenopus tropicalis (tropical clawed frog)	omp	NP_989065.2
Mus musculus (house mouse)	Omp	NP_035140.1
Bos taurus (cattle)	OMP	XP_005216395.1
Rattus norvegicus (Norway rat)	Omp	NP_036748.1
Danio rerio (zebrafish)	ompa	NP_001020356.1
Gallus gallus (chicken)	OMP	XP_004938999.1
Danio rerio (zebrafish)	ompb	NP_775388.2

Gene Ontology
Bibliography

Related articles in PubMed

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners.
Behrens M, Margolis JW, Margolis FL
Journal of neurochemistry86(5)1289-96(2003 Sep)

Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction.
Baldisseri DM, Margolis JW, Weber DJ, Koo JH, Margolis FL
Journal of molecular biology319(3)823-37(2002 Jun)

Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons.
Buiakova OI, Baker H, Scott JW, Farbman A, Kream R, Grillo M, Franzen L, Richman M, Davis LM, Abbondanzo S, Stewart CL, Margolis FL
Proceedings of the National Academy of Sciences of the United States of America93(18)9858-63(1996 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following OMP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OMP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30874	NM_006189.1 Latest version!	Homo sapiens olfactory marker protein (OMP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OMP ( NM_006189.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_006180.1 Homo sapiens olfactory marker protein (OMP), mRNA.

Price & Availability↑

CloneID	OHu30874
Clone ID Related Accession (Same CDS sequence)	NM_006189.1
Accession Version	NM_006189.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	olfactory marker protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000752.4. ##Evidence-Data-START## Transcript is intronless :: BC069365.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000529803.1/ ENSP00000436376.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCGGAGG ACAGGCCGCA GCAGCCGCAG CTGGACATGC CGCTGGTCCT GGACCAGGGC 
CTGACCAGGC AGATGCGGCT ACGCGTGGAG AGCCTGAAGC AGCGCGGGGA GAAGCGCCAG 
GATGGGGAGA AGCTGCTGCA GCCAGCGGAG TCTGTGTACC GCCTCAACTT CACCCAGCAG 
CAGCGGCTAC AGTTCGAGCG CTGGAATGTC GTGCTGGACA AGCCGGGCAA GGTCACCATC 
ACAGGCACCT CGCAGAACTG GACGCCTGAC CTCACCAACC TCATGACACG CCAGCTGCTG 
GACCCCACTG CCATCTTCTG GCGCAAGGAG GACTCGGATG CCATAGATTG GAATGAGGCC 
GACGCCCTGG AGTTTGGGGA GCGCCTGTCG GACCTGGCCA AGATCCGCAA GGTCATGTAC 
TTCCTCGTCA CCTTTGGCGA GGGTGTGGAG CCCGCCAACC TCAAGGCCTC CGTGGTTTTT 
AACCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006180.1
CDS	1..492
Translation	MAEDRPQQPQLDMPLVLDQGLTRQMRLRVESLKQRGEKRQDGEKLLQPAESVYRLNFTQQQRLQFERWNVVLDKPGKVTITGTSQNWTPDLTNLMTRQLLDPTAIFWRKEDSDAIDWNEADALEFGERLSDLAKIRKVMYFLVTFGEGVEPANLKASVVFNQL

Target ORF information:

RefSeq Version	NM_006189.1
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory marker protein (OMP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006189.1

ORF Insert Sequence:

ATGGCGGAGG ACAGGCCGCA GCAGCCGCAG CTGGACATGC CGCTGGTCCT GGACCAGGGC 
CTGACCAGGC AGATGCGGCT ACGCGTGGAG AGCCTGAAGC AGCGCGGGGA GAAGCGCCAG 
GATGGGGAGA AGCTGCTGCA GCCAGCGGAG TCTGTGTACC GCCTCAACTT CACCCAGCAG 
CAGCGGCTAC AGTTCGAGCG CTGGAATGTC GTGCTGGACA AGCCGGGCAA GGTCACCATC 
ACAGGCACCT CGCAGAACTG GACGCCTGAC CTCACCAACC TCATGACACG CCAGCTGCTG 
GACCCCACTG CCATCTTCTG GCGCAAGGAG GACTCGGATG CCATAGATTG GAATGAGGCC 
GACGCCCTGG AGTTTGGGGA GCGCCTGTCG GACCTGGCCA AGATCCGCAA GGTCATGTAC 
TTCCTCGTCA CCTTTGGCGA GGGTGTGGAG CCCGCCAACC TCAAGGCCTC CGTGGTTTTT 
AACCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners.
Journal of neurochemistry86(5)1289-96(2003 Sep)
Behrens M,Margolis JW,Margolis FL

Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction.
Journal of molecular biology319(3)823-37(2002 Jun)
Baldisseri DM,Margolis JW,Weber DJ,Koo JH,Margolis FL

Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons.
Proceedings of the National Academy of Sciences of the United States of America93(18)9858-63(1996 Sep)
Buiakova OI,Baker H,Scott JW,Farbman A,Kream R,Grillo M,Franzen L,Richman M,Davis LM,Abbondanzo S,Stewart CL,Margolis FL

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OMP cDNA ORF clone, Homo sapiens(human)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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