ATP1B3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP1B3
Entrez Gene ID	483
Full Name	ATPase Na+/K+ transporting subunit beta 3
Synonyms	ATPB-3,CD298
General protein information	Preferred Names ATPase Na+/K+ transporting subunit beta 3 Names sodium/potassium-transporting ATPase subunit beta-3 ATPase, Na+/K+ transporting, beta 3 polypeptide Na, K-ATPase beta-3 polypeptide sodium pump subunit beta-3 sodium-potassium ATPase subunit beta 3 (non-catalytic) sodium/potassium-dependent ATPase subunit beta-3 sodium/potassium-transporting ATPase beta-3 chain
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q23
Summary	The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008].
Disorder MIM:	601867

mRNA and Protein(s)

mRNA	Protein	Name
NM_001679.2	NP_001670.1	sodium/potassium-transporting ATPase subunit beta-3
NM_001679.4	NP_001670.1	sodium/potassium-transporting ATPase subunit beta-3
NM_001679.3	NP_001670.1	sodium/potassium-transporting ATPase subunit beta-3

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	atp1b3	NP_989087.1
Homo sapiens (human)	ATP1B3	NP_001670.1
Pan troglodytes (chimpanzee)	ATP1B3	XP_001154579.2
Bos taurus (cattle)	ATP1B3	NP_001030470.1
Gallus gallus (chicken)	ATP1B3	NP_990866.1
Danio rerio (zebrafish)	atp1b3a	NP_571296.1
Canis lupus familiaris (dog)	ATP1B3	XP_005634705.1
	ATP1B3	XP_001107546.2
Danio rerio (zebrafish)	atp1b3b	NP_571745.1
Mus musculus (house mouse)	Atp1b3	NP_031528.1
Rattus norvegicus (Norway rat)	Atp1b3	NP_037045.1

Gene Ontology
Bibliography

Related articles in PubMed

ATP1B3: a virus-induced host factor against EV71 replication by up-regulating the production of type-I interferons.
Lu Y, Hou H, Wang F, Qiao L, Wang X, Yu J, Liu W, Sun Z
Virology49628-34(2016 09)

ATP1B3 Protein Modulates the Restriction of HIV-1 Production and Nuclear Factor ? Light Chain Enhancer of Activated B Cells (NF-?B) Activation by BST-2.
Nishitsuji H, Sugiyama R, Abe M, Takaku H
The Journal of biological chemistry291(9)4754-62(2016 Feb)

Identification and characterization of angiogenesis targets through proteomic profiling of endothelial cells in human cancer tissues.
Mesri M, Birse C, Heidbrink J, McKinnon K, Brand E, Bermingham CL, Feild B, Fitzhugh W, He T, Ruben S, Moore PA
PloS one8(11)e78885(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our study demonstrated that ATP1B3 inhibit EV71 replication by enhancing the production of type-I interferons, which could act as a potential therapeutic target in EV71 infection.
Title: ATP1B3: a virus-induced host factor against EV71 replication by up-regulating the production of type-I interferons.

Data suggest that ATP1B3 is binding partner of BST-2 and regulates stability of BST-2; ATP1B3 is co-factor that accelerates BST-2 degradation and reduces BST-2-mediated restriction of HIV-1 replication/tropism and NFkappaB activation.
Title: ATP1B3 Protein Modulates the Restriction of HIV-1 Production and Nuclear Factor ? Light Chain Enhancer of Activated B Cells (NF-?B) Activation by BST-2.

B7H3 and ATP1B3 are overexpressed in tumor endothelial cells, favoring an angiogenic phenotype.
Title: Identification and characterization of angiogenesis targets through proteomic profiling of endothelial cells in human cancer tissues.

Elevated Na+ -K+ -ATPase activity postexercise may contribute to reduced fatigue after training.
Title: Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

These results evidenced that the beta3 subunit of Na, K ATPase is expressed on RBC membrane but the epitope recognized by mAb P-3E10 is hidden in normal RBCs. we showed the association of beta3 subunit and alpha subunit of Na, K ATPase.
Title: Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells.

The following ATP1B3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP1B3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29398	NM_001679.4 Latest version!	Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu29398	NM_001679.2	Homo sapiens ATPase, Na+/K+ transporting, beta 3 polypeptide (ATP1B3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu29398	NM_001679.3	Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP1B3 ( NM_001679.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001670.1 Homo sapiens ATPase, Na+/K+ transporting, beta 3 polypeptide (ATP1B3), mRNA.

Price & Availability↑

CloneID	OHu29398
Clone ID Related Accession (Same CDS sequence)	NM_001679.2 , NM_001679.4 , NM_001679.3
Accession Version	NM_001679.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	sodium/potassium-transporting ATPase subunit beta-3
Comment

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001670.1
Translation	MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA

Target ORF information:

RefSeq Version	NM_001679.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens ATPase, Na+/K+ transporting, beta 3 polypeptide (ATP1B3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001679.2

ORF Insert Sequence:

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP1B3 ( NM_001679.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001670.1 Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.

Price & Availability↑

CloneID	OHu29398
Clone ID Related Accession (Same CDS sequence)	NM_001679.2 , NM_001679.4 , NM_001679.3
Accession Version	NM_001679.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	sodium/potassium-transporting ATPase subunit beta-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK131061.1, AC112504.6, DB307448.1 and CN295803.1. On Nov 22, 2018 this sequence version replaced NM_001679.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.77974.1, SRR1660807.202974.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000286371.8/ ENSP00000286371.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001670.1
CDS	160..999
Translation	MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA

Target ORF information:

RefSeq Version	NM_001679.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001679.4

ORF Insert Sequence:

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP1B3 ( NM_001679.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001670.1 Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.

Price & Availability↑

CloneID	OHu29398
Clone ID Related Accession (Same CDS sequence)	NM_001679.2 , NM_001679.4 , NM_001679.3
Accession Version	NM_001679.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	sodium/potassium-transporting ATPase subunit beta-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY040306.1, AK131061.1, AC112504.6, DB307448.1 and CN295803.1. On Jun 15, 2016 this sequence version replaced NM_001679.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.24470.1, SRR1660807.202974.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001670.1
CDS	211..1050
Translation	MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA

Target ORF information:

RefSeq Version	NM_001679.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase Na+/K+ transporting subunit beta 3 (ATP1B3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001679.3

ORF Insert Sequence:

ATGACGAAGA ACGAGAAGAA GTCCCTCAAC CAGAGCCTGG CCGAGTGGAA GCTCTTCATC 
TACAACCCGA CCACCGGAGA ATTCCTGGGG CGCACCGCCA AGAGCTGGGG TTTGATCTTG 
CTCTTCTACC TAGTTTTTTA TGGGTTCCTG GCTGCACTCT TCTCATTCAC GATGTGGGTT 
ATGCTTCAGA CTCTCAACGA TGAGGTTCCA AAATACCGTG ACCAGATTCC TAGCCCAGGA 
CTCATGGTTT TTCCAAAACC AGTGACCGCA TTGGAATATA CATTCAGTAG GTCTGATCCA 
ACTTCGTATG CAGGGTACAT TGAAGACCTT AAGAAGTTTC TAAAACCATA TACTTTAGAA 
GAACAGAAGA ACCTCACAGT CTGTCCTGAT GGAGCACTTT TTGAACAGAA GGGTCCAGTT 
TATGTTGCAT GTCAGTTTCC TATTTCATTA CTTCAAGCAT GCAGTGGTAT GAATGATCCT 
GATTTTGGCT ATTCTCAAGG AAACCCTTGT ATTCTTGTGA AAATGAACAG AATAATTGGA 
TTAAAGCCTG AAGGAGTGCC AAGGATAGAT TGTGTTTCAA AGAATGAAGA TATACCAAAT 
GTAGCAGTTT ATCCTCATAA TGGAATGATA GACTTAAAAT ATTTCCCATA TTATGGGAAA 
AAACTGCATG TTGGGTATCT ACAGCCATTG GTTGCTGTTC AGGTCAGCTT TGCTCCTAAC 
AACACTGGGA AAGAAGTAAC AGTTGAGTGC AAGATTGATG GATCAGCCAA CCTAAAAAGT 
CAGGATGATC GTGACAAGTT TTTGGGACGA GTTATGTTCA AAATCACAGC ACGTGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATP1B3: a virus-induced host factor against EV71 replication by up-regulating the production of type-I interferons.
Virology49628-34(2016 09)
Lu Y,Hou H,Wang F,Qiao L,Wang X,Yu J,Liu W,Sun Z

ATP1B3 Protein Modulates the Restriction of HIV-1 Production and Nuclear Factor ? Light Chain Enhancer of Activated B Cells (NF-?B) Activation by BST-2.
The Journal of biological chemistry291(9)4754-62(2016 Feb)
Nishitsuji H,Sugiyama R,Abe M,Takaku H

Identification and characterization of angiogenesis targets through proteomic profiling of endothelial cells in human cancer tissues.
PloS one8(11)e78885(2013)
Mesri M,Birse C,Heidbrink J,McKinnon K,Brand E,Bermingham CL,Feild B,Fitzhugh W,He T,Ruben S,Moore PA

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ATP1B3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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