NFKBIB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFKBIB
Entrez Gene ID	4793
Full Name	NFKB inhibitor beta
Synonyms	IKBB,TRIP9
General protein information	Preferred Names NFKB inhibitor beta Names NF-kappa-B inhibitor beta I-kappa-B-beta NF-kappa-BIB TR-interacting protein 9 TRIP-9 ikB-B ikB-beta ikappaBbeta nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta thyroid receptor-interacting protein 9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Disorder MIM:	604495

mRNA and Protein(s)

mRNA	Protein	Name
XM_006723227.2	XP_006723290.2	NF-kappa-B inhibitor beta isoform X1
NM_001369699.1	NP_001356628.1	NF-kappa-B inhibitor beta isoform 3
NM_002503.4	NP_002494.2	NF-kappa-B inhibitor beta isoform 1
NM_001243116.1	NP_001230045.1	NF-kappa-B inhibitor beta isoform 2
NM_002503.5	NP_002494.2	NF-kappa-B inhibitor beta isoform 1
XM_006723227.3	XP_006723290.3	NF-kappa-B inhibitor beta isoform X2
NM_001369700.1	NP_001356629.1	NF-kappa-B inhibitor beta isoform 4
XM_006723226.2	XP_006723289.2	NF-kappa-B inhibitor beta isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nfkbib	NP_110494.2
Pan troglodytes (chimpanzee)	NFKBIB	XP_001168499.1
Mus musculus (house mouse)	Nfkbib	NP_035038.2
	NFKBIB	XP_001085582.1
Bos taurus (cattle)	NFKBIB	NP_001069340.1
Danio rerio (zebrafish)	si:dkeyp-110c7.1	NP_001122267.1
Homo sapiens (human)	NFKBIB	NP_002494.2
Canis lupus familiaris (dog)	NFKBIB	XP_541633.1
Gallus gallus (chicken)	NFKBIB	XP_003643552.1

Gene Ontology
Bibliography

Related articles in PubMed

Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of I?B and Downregulation of Survivin.
Nair JS, Musi E, Schwartz GK
Clinical cancer research : an official journal of the American Association for Cancer Research23(15)4301-4311(2017 Aug)

Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival.
Othumpangat S, Bryan NB, Beezhold DH, Noti JD
Viruses9(5)(2017 Apr)

IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-?B-mediated signalling.
Phoon YP, Cheung AK, Cheung FM, Chan KF, Wong S, Wong BW, Tung SY, Yau CC, Ng WT, Lung ML
International journal of cancer138(1)160-70(2016 Jan)

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Chen TC, Lin KT, Chen CH, Lee SA, Lee PY, Liu YW, Kuo YL, Wang FS, Lai JM, Huang CY
Journal of proteome research13(12)5339-46(2014 Dec)

Genetic polymorphisms and risk of recurrent wheezing in pediatric age.
Esposito S, Ierardi V, Daleno C, Scala A, Terranova L, Tagliabue C, Rios WP, Pelucchi C, Principi N
BMC pulmonary medicine14162(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our data establish the importance of a novel tumor suppressive IKBB gene in abrogating angiogenesis in NPC via the NF-kappaB signalling pathway.
Title: IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-?B-mediated signalling.

NFKBIBrs3136641TT single nucleotide polymorphism was associated with a significantly decreased risk of developing wheezing.
Title: Genetic polymorphisms and risk of recurrent wheezing in pediatric age.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.

The following NFKBIB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFKBIB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19023	NM_002503.5 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu55838	NM_001243116.1 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu55838	XM_006723227.2 Latest version!	Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu59264	XM_006723226.2 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu108022	NM_001369700.1 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu108023	NM_001369699.1 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu88490	XM_006723227.3 Latest version!	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu19023	NM_002503.4	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFKBIB ( NM_002503.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002494.2 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19023
Clone ID Related Accession (Same CDS sequence)	NM_002503.4 , NM_002503.5
Accession Version	NM_002503.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA633677.1, BC015528.1 and AI684894.1. This sequence is a reference standard in the RefSeqGene project. On Jul 22, 2011 this sequence version replaced NM_002503.3. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.330321.1, SRR1163657.297667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG ATGAATACGA CGACATTGTG GTTCACAGCA GCCGCAGCCA AACCCGGCTG 
CCTCCCACCC CAGCCTCAAA ACCTCTTCCT GACGACCCCC GCCCCGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002494.2
CDS	104..1174
Translation	MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	NM_002503.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002503.4

ORF Insert Sequence:

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG ATGAATACGA CGACATTGTG GTTCACAGCA GCCGCAGCCA AACCCGGCTG 
CCTCCCACCC CAGCCTCAAA ACCTCTTCCT GACGACCCCC GCCCCGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( NM_002503.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002494.2 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19023
Clone ID Related Accession (Same CDS sequence)	NM_002503.4 , NM_002503.5
Accession Version	NM_002503.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA633677.1, BC015528.1 and AI684894.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002503.4. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.297667.1, SRR1163655.559868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000313582.6/ ENSP00000312988.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG ATGAATACGA CGACATTGTG GTTCACAGCA GCCGCAGCCA AACCCGGCTG 
CCTCCCACCC CAGCCTCAAA ACCTCTTCCT GACGACCCCC GCCCCGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002494.2
CDS	65..1135
Translation	MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	NM_002503.5
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002503.5

ORF Insert Sequence:

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG ATGAATACGA CGACATTGTG GTTCACAGCA GCCGCAGCCA AACCCGGCTG 
CCTCCCACCC CAGCCTCAAA ACCTCTTCCT GACGACCCCC GCCCCGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( NM_001243116.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001230045.1 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu55838
Clone ID Related Accession (Same CDS sequence)	XM_006723227.2 , NM_001243116.1
Accession Version	NM_001243116.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI520169.1, BC015528.1 and AI684894.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and a shorter isoform (2) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI520169.1, ERR279864.1705.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTGC AGAATGACCT AGGCCAGACA GCCCTGCACC TGGCAGCCAT CCTGGGGGAG 
ACATCCACGG TGGAGAAGCT GTACGCAGCA GGCGCCGGGC TGTGTGTGGC GGAGCGTAGG 
GGCCACACGG CGCTGCACCT GGCCTGCCGT GTGGGGGCAC ACGCCTGTGC CCGTGCCCTG 
CTTCAGCCCC GCCCCCGGCG CCCCAGGGAA GCCCCCGACA CCTACCTCGC TCAGGGCCCT 
GACCGTACTC CCGACACCAA CCATACCCCT GTCGCCTTGT ACCCCGATTC CGACTTGGAG 
AAGGAAGAAG AGGAGAGTGA GGAGGACTGG AAGCTGCAGC TGGAGGCTGA AAACTACGAG 
GGCCACACCC CACTCCACGT GGCCGTTATC CACAAAGATG TGGAGATGGT CCGGCTGCTC 
CGAGATGCTG GAGCTGACCT TGACAAACCG GAGCCCACGT GCGGCCGGAG CCCCCTTCAT 
TTGGCAGTGG AGGCCCAGGC AGCCGATGTG CTGGAGCTTC TCCTGAGGGC AGGCGCGAAC 
CCTGCTGCCC GCATGTACGG TGGCCGCACC CCACTCGGCA GTGCCATGCT CCGGCCCAAC 
CCCATCCTCG CCCGCCTCCT CCGTGCACAC GGAGCCCCTG AGCCCGAGGG CGAGGACGAG 
AAATCCGGCC CCTGCAGCAG CAGTAGCGAC AGCGACAGCG GAGACGAGGG CGATGAATAC 
GACGACATTG TGGTTCACAG CAGCCGCAGC CAAACCCGGC TGCCTCCCAC CCCAGCCTCA 
AAACCTCTTC CTGACGACCC CCGCCCCGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230045.1
CDS	120..932
Translation	MDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	NM_001243116.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243116.1

ORF Insert Sequence:

ATGGACCTGC AGAATGACCT AGGCCAGACA GCCCTGCACC TGGCAGCCAT CCTGGGGGAG 
ACATCCACGG TGGAGAAGCT GTACGCAGCA GGCGCCGGGC TGTGTGTGGC GGAGCGTAGG 
GGCCACACGG CGCTGCACCT GGCCTGCCGT GTGGGGGCAC ACGCCTGTGC CCGTGCCCTG 
CTTCAGCCCC GCCCCCGGCG CCCCAGGGAA GCCCCCGACA CCTACCTCGC TCAGGGCCCT 
GACCGTACTC CCGACACCAA CCATACCCCT GTCGCCTTGT ACCCCGATTC CGACTTGGAG 
AAGGAAGAAG AGGAGAGTGA GGAGGACTGG AAGCTGCAGC TGGAGGCTGA AAACTACGAG 
GGCCACACCC CACTCCACGT GGCCGTTATC CACAAAGATG TGGAGATGGT CCGGCTGCTC 
CGAGATGCTG GAGCTGACCT TGACAAACCG GAGCCCACGT GCGGCCGGAG CCCCCTTCAT 
TTGGCAGTGG AGGCCCAGGC AGCCGATGTG CTGGAGCTTC TCCTGAGGGC AGGCGCGAAC 
CCTGCTGCCC GCATGTACGG TGGCCGCACC CCACTCGGCA GTGCCATGCT CCGGCCCAAC 
CCCATCCTCG CCCGCCTCCT CCGTGCACAC GGAGCCCCTG AGCCCGAGGG CGAGGACGAG 
AAATCCGGCC CCTGCAGCAG CAGTAGCGAC AGCGACAGCG GAGACGAGGG CGATGAATAC 
GACGACATTG TGGTTCACAG CAGCCGCAGC CAAACCCGGC TGCCTCCCAC CCCAGCCTCA 
AAACCTCTTC CTGACGACCC CCGCCCCGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( XM_006723227.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723290.2 Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant X2, mRNA.

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CloneID	OHu55838
Clone ID Related Accession (Same CDS sequence)	XM_006723227.2 , NM_001243116.1
Accession Version	XM_006723227.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	NF-kappa-B inhibitor beta isoform X1
Comment

ATGGACCTGC AGAATGACCT AGGCCAGACA GCCCTGCACC TGGCAGCCAT CCTGGGGGAG 
ACATCCACGG TGGAGAAGCT GTACGCAGCA GGCGCCGGGC TGTGTGTGGC GGAGCGTAGG 
GGCCACACGG CGCTGCACCT GGCCTGCCGT GTGGGGGCAC ACGCCTGTGC CCGTGCCCTG 
CTTCAGCCCC GCCCCCGGCG CCCCAGGGAA GCCCCCGACA CCTACCTCGC TCAGGGCCCT 
GACCGTACTC CCGACACCAA CCATACCCCT GTCGCCTTGT ACCCCGATTC CGACTTGGAG 
AAGGAAGAAG AGGAGAGTGA GGAGGACTGG AAGCTGCAGC TGGAGGCTGA AAACTACGAG 
GGCCACACCC CACTCCACGT GGCCGTTATC CACAAAGATG TGGAGATGGT CCGGCTGCTC 
CGAGATGCTG GAGCTGACCT TGACAAACCG GAGCCCACGT GCGGCCGGAG CCCCCTTCAT 
TTGGCAGTGG AGGCCCAGGC AGCCGATGTG CTGGAGCTTC TCCTGAGGGC AGGCGCGAAC 
CCTGCTGCCC GCATGTACGG TGGCCGCACC CCACTCGGCA GTGCCATGCT CCGGCCCAAC 
CCCATCCTCG CCCGCCTCCT CCGTGCACAC GGAGCCCCTG AGCCCGAGGG CGAGGACGAG 
AAATCCGGCC CCTGCAGCAG CAGTAGCGAC AGCGACAGCG GAGACGAGGG CGATGAATAC 
GACGACATTG TGGTTCACAG CAGCCGCAGC CAAACCCGGC TGCCTCCCAC CCCAGCCTCA 
AAACCTCTTC CTGACGACCC CCGCCCCGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723290.2
Translation	MDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	XM_006723227.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723227.2

ORF Insert Sequence:

ATGGACCTGC AGAATGACCT AGGCCAGACA GCCCTGCACC TGGCAGCCAT CCTGGGGGAG 
ACATCCACGG TGGAGAAGCT GTACGCAGCA GGCGCCGGGC TGTGTGTGGC GGAGCGTAGG 
GGCCACACGG CGCTGCACCT GGCCTGCCGT GTGGGGGCAC ACGCCTGTGC CCGTGCCCTG 
CTTCAGCCCC GCCCCCGGCG CCCCAGGGAA GCCCCCGACA CCTACCTCGC TCAGGGCCCT 
GACCGTACTC CCGACACCAA CCATACCCCT GTCGCCTTGT ACCCCGATTC CGACTTGGAG 
AAGGAAGAAG AGGAGAGTGA GGAGGACTGG AAGCTGCAGC TGGAGGCTGA AAACTACGAG 
GGCCACACCC CACTCCACGT GGCCGTTATC CACAAAGATG TGGAGATGGT CCGGCTGCTC 
CGAGATGCTG GAGCTGACCT TGACAAACCG GAGCCCACGT GCGGCCGGAG CCCCCTTCAT 
TTGGCAGTGG AGGCCCAGGC AGCCGATGTG CTGGAGCTTC TCCTGAGGGC AGGCGCGAAC 
CCTGCTGCCC GCATGTACGG TGGCCGCACC CCACTCGGCA GTGCCATGCT CCGGCCCAAC 
CCCATCCTCG CCCGCCTCCT CCGTGCACAC GGAGCCCCTG AGCCCGAGGG CGAGGACGAG 
AAATCCGGCC CCTGCAGCAG CAGTAGCGAC AGCGACAGCG GAGACGAGGG CGATGAATAC 
GACGACATTG TGGTTCACAG CAGCCGCAGC CAAACCCGGC TGCCTCCCAC CCCAGCCTCA 
AAACCTCTTC CTGACGACCC CCGCCCCGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( XM_006723226.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723289.2 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X1, mRNA.

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CloneID	OHu59264
Clone ID Related Accession (Same CDS sequence)	XM_006723226.2
Accession Version	XM_006723226.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006723226.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGGTG CGACAGCGGC CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC 
CTGGGTTGGG CGCGGAGTTG GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG 
TCACTGAGGA TGGGGACACG CTTCTCGGCC GGCACTGAGT ACATGGACCT GCAGAATGAC 
CTAGGCCAGA CAGCCCTGCA CCTGGCAGCC ATCCTGGGGG AGACATCCAC GGTGGAGAAG 
CTGTACGCAG CAGGCGCCGG GCTGTGTGTG GCGGAGCGTA GGGGCCACAC GGCGCTGCAC 
CTGGCCTGCC GTGTGGGGGC ACACGCCTGT GCCCGTGCCC TGCTTCAGCC CCGCCCCCGG 
CGCCCCAGGG AAGCCCCCGA CACCTACCTC GCTCAGGGCC CTGACCGTAC TCCCGACACC 
AACCATACCC CTGTCGCCTT GTACCCCGAT TCCGACTTGG AGAAGGAAGA AGAGGAGAGT 
GAGGAGGACT GGAAGCTGCA GCTGGAGGCT GAAAACTACG AGGGCCACAC CCCACTCCAC 
GTGGCCGTTA TCCACAAAGA TGTGGAGATG GTCCGGCTGC TCCGAGATGC TGGAGCTGAC 
CTTGACAAAC CGGAGCCCAC GTGCGGCCGG AGCCCCCTTC ATTTGGCAGT GGAGGCCCAG 
GCAGCCGATG TGCTGGAGCT TCTCCTGAGG GCAGGCGCGA ACCCTGCTGC CCGCATGTAC 
GGTGGCCGCA CCCCACTCGG CAGTGCCATG CTCCGGCCCA ACCCCATCCT CGCCCGCCTC 
CTCCGTGCAC ACGGAGCCCC TGAGCCCGAG GGCGAGGACG AGAAATCCGG CCCCTGCAGC 
AGCAGTAGCG ACAGCGACAG CGGAGACGAG GGCGATGAAT ACGACGACAT TGTGGTTCAC 
AGCAGCCGCA GCCAAACCCG GCTGCCTCCC ACCCCAGCCT CAAAACCTCT TCCTGACGAC 
CCCCGCCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723289.2
CDS	136..1110
Translation	MNGATAAWAPWVRTQRPPEDLGWARSWARGCRGLPSSSATSLRMGTRFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	XM_006723226.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723226.2

ORF Insert Sequence:

ATGAATGGTG CGACAGCGGC CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC 
CTGGGTTGGG CGCGGAGTTG GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG 
TCACTGAGGA TGGGGACACG CTTCTCGGCC GGCACTGAGT ACATGGACCT GCAGAATGAC 
CTAGGCCAGA CAGCCCTGCA CCTGGCAGCC ATCCTGGGGG AGACATCCAC GGTGGAGAAG 
CTGTACGCAG CAGGCGCCGG GCTGTGTGTG GCGGAGCGTA GGGGCCACAC GGCGCTGCAC 
CTGGCCTGCC GTGTGGGGGC ACACGCCTGT GCCCGTGCCC TGCTTCAGCC CCGCCCCCGG 
CGCCCCAGGG AAGCCCCCGA CACCTACCTC GCTCAGGGCC CTGACCGTAC TCCCGACACC 
AACCATACCC CTGTCGCCTT GTACCCCGAT TCCGACTTGG AGAAGGAAGA AGAGGAGAGT 
GAGGAGGACT GGAAGCTGCA GCTGGAGGCT GAAAACTACG AGGGCCACAC CCCACTCCAC 
GTGGCCGTTA TCCACAAAGA TGTGGAGATG GTCCGGCTGC TCCGAGATGC TGGAGCTGAC 
CTTGACAAAC CGGAGCCCAC GTGCGGCCGG AGCCCCCTTC ATTTGGCAGT GGAGGCCCAG 
GCAGCCGATG TGCTGGAGCT TCTCCTGAGG GCAGGCGCGA ACCCTGCTGC CCGCATGTAC 
GGTGGCCGCA CCCCACTCGG CAGTGCCATG CTCCGGCCCA ACCCCATCCT CGCCCGCCTC 
CTCCGTGCAC ACGGAGCCCC TGAGCCCGAG GGCGAGGACG AGAAATCCGG CCCCTGCAGC 
AGCAGTAGCG ACAGCGACAG CGGAGACGAG GGCGATGAAT ACGACGACAT TGTGGTTCAC 
AGCAGCCGCA GCCAAACCCG GCTGCCTCCC ACCCCAGCCT CAAAACCTCT TCCTGACGAC 
CCCCGCCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( NM_001369700.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001356629.1 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 5, mRNA.

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CloneID	OHu108022
Clone ID Related Accession (Same CDS sequence)	NM_001369700.1
Accession Version	NM_001369700.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011455.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.328360.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGGAAGA AGAGGAGAGT 
GAGGAGGACT GGAAGCTGCA GCTGGAGGCT GAAAACTACG AGGGCCACAC CCCACTCCAC 
GTGGCCGTTA TCCACAAAGA TGTGGAGATG GTCCGGCTGC TCCGAGATGC TGGAGCTGAC 
CTTGACAAAC CGGAGCCCAC GTGCGGCCGG AGCCCCCTTC ATTTGGCAGT GGAGGCCCAG 
GCAGCCGATG TGCTGGAGCT TCTCCTGAGG GCAGGCGCGA ACCCTGCTGC CCGCATGTAC 
GGTGGCCGCA CCCCACTCGG CAGTGCCATG CTCCGGCCCA ACCCCATCCT CGCCCGCCTC 
CTCCGTGCAC ACGGAGCCCC TGAGCCCGAG GGCGAGGACG AGAAATCCGG CCCCTGCAGC 
AGCAGTAGCG ACAGCGACAG CGGAGACGAG GGCGATGAAT ACGACGACAT TGTGGTTCAC 
AGCAGCCGCA GCCAAACCCG GCTGCCTCCC ACCCCAGCCT CAAAACCTCT TCCTGACGAC 
CCCCGCCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001356629.1
CDS	65..859
Translation	MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	NM_001369700.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001369700.1

ORF Insert Sequence:

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGGAAGA AGAGGAGAGT 
GAGGAGGACT GGAAGCTGCA GCTGGAGGCT GAAAACTACG AGGGCCACAC CCCACTCCAC 
GTGGCCGTTA TCCACAAAGA TGTGGAGATG GTCCGGCTGC TCCGAGATGC TGGAGCTGAC 
CTTGACAAAC CGGAGCCCAC GTGCGGCCGG AGCCCCCTTC ATTTGGCAGT GGAGGCCCAG 
GCAGCCGATG TGCTGGAGCT TCTCCTGAGG GCAGGCGCGA ACCCTGCTGC CCGCATGTAC 
GGTGGCCGCA CCCCACTCGG CAGTGCCATG CTCCGGCCCA ACCCCATCCT CGCCCGCCTC 
CTCCGTGCAC ACGGAGCCCC TGAGCCCGAG GGCGAGGACG AGAAATCCGG CCCCTGCAGC 
AGCAGTAGCG ACAGCGACAG CGGAGACGAG GGCGATGAAT ACGACGACAT TGTGGTTCAC 
AGCAGCCGCA GCCAAACCCG GCTGCCTCCC ACCCCAGCCT CAAAACCTCT TCCTGACGAC 
CCCCGCCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( NM_001369699.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001356628.1 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 4, mRNA.

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CloneID	OHu108023
Clone ID Related Accession (Same CDS sequence)	NM_001369699.1
Accession Version	NM_001369699.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB209784.1 and AC011455.6. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138512.75279.1, AB209784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG TGAGTCAGGA GGAGAGACAG GGCAGCCCAG CTGGGGGGTC AGGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001356628.1
CDS	65..1081
Translation	MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGVSQEERQGSPAGGSG

Target ORF information:

RefSeq Version	NM_001369699.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001369699.1

ORF Insert Sequence:

ATGGCTGGGG TCGCGTGCTT GGGAAAAGCT GCCGACGCAG ATGAATGGTG CGACAGCGGC 
CTGGGCTCCC TGGGTCCGGA CGCAGCGGCC CCCGGAGGAC CTGGGTTGGG CGCGGAGTTG 
GGCCCGGGGC TGTCGTGGGC TCCCCTCGTC TTCGGCTACG TCACTGAGGA TGGGGACACG 
GCACTGCACT TGGCTGTGAT TCATCAGCAT GAACCCTTCC TGGATTTTCT TCTAGGCTTC 
TCGGCCGGCA CTGAGTACAT GGACCTGCAG AATGACCTAG GCCAGACAGC CCTGCACCTG 
GCAGCCATCC TGGGGGAGAC ATCCACGGTG GAGAAGCTGT ACGCAGCAGG CGCCGGGCTG 
TGTGTGGCGG AGCGTAGGGG CCACACGGCG CTGCACCTGG CCTGCCGTGT GGGGGCACAC 
GCCTGTGCCC GTGCCCTGCT TCAGCCCCGC CCCCGGCGCC CCAGGGAAGC CCCCGACACC 
TACCTCGCTC AGGGCCCTGA CCGTACTCCC GACACCAACC ATACCCCTGT CGCCTTGTAC 
CCCGATTCCG ACTTGGAGAA GGAAGAAGAG GAGAGTGAGG AGGACTGGAA GCTGCAGCTG 
GAGGCTGAAA ACTACGAGGG CCACACCCCA CTCCACGTGG CCGTTATCCA CAAAGATGTG 
GAGATGGTCC GGCTGCTCCG AGATGCTGGA GCTGACCTTG ACAAACCGGA GCCCACGTGC 
GGCCGGAGCC CCCTTCATTT GGCAGTGGAG GCCCAGGCAG CCGATGTGCT GGAGCTTCTC 
CTGAGGGCAG GCGCGAACCC TGCTGCCCGC ATGTACGGTG GCCGCACCCC ACTCGGCAGT 
GCCATGCTCC GGCCCAACCC CATCCTCGCC CGCCTCCTCC GTGCACACGG AGCCCCTGAG 
CCCGAGGGCG AGGACGAGAA ATCCGGCCCC TGCAGCAGCA GTAGCGACAG CGACAGCGGA 
GACGAGGGCG TGAGTCAGGA GGAGAGACAG GGCAGCCCAG CTGGGGGGTC AGGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIB ( XM_006723227.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723290.3 Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu88490
Clone ID Related Accession (Same CDS sequence)	XM_006723227.3
Accession Version	XM_006723227.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006723227.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGCGG TGCTGAAGCC CTTGAGGCTG TCACCGACCG CTCTGTCCCG TCACCAACCA 
CTGTGTCCCG TCACCGACTG CTCTGTCCTG TCACCGACTG CTCTGTCCCG TGACGGCACC 
AGAAATGGGA GTGGCCGTGA TAGGGCACAG AACTACAACT CTCAGCAGAC ATTGCGGCCG 
CAGACGCGCT TTCGTACAAC ACCCAGAGCG CCCCAGTTAG GCTTCTCGGC CGGCACTGAG 
TACATGGACC TGCAGAATGA CCTAGGCCAG ACAGCCCTGC ACCTGGCAGC CATCCTGGGG 
GAGACATCCA CGGTGGAGAA GCTGTACGCA GCAGGCGCCG GGCTGTGTGT GGCGGAGCGT 
AGGGGCCACA CGGCGCTGCA CCTGGCCTGC CGTGTGGGGG CACACGCCTG TGCCCGTGCC 
CTGCTTCAGC CCCGCCCCCG GCGCCCCAGG GAAGCCCCCG ACACCTACCT CGCTCAGGGC 
CCTGACCGTA CTCCCGACAC CAACCATACC CCTGTCGCCT TGTACCCCGA TTCCGACTTG 
GAGAAGGAAG AAGAGGAGAG TGAGGAGGAC TGGAAGCTGC AGCTGGAGGC TGAAAACTAC 
GAGGGCCACA CCCCACTCCA CGTGGCCGTT ATCCACAAAG ATGTGGAGAT GGTCCGGCTG 
CTCCGAGATG CTGGAGCTGA CCTTGACAAA CCGGAGCCCA CGTGCGGCCG GAGCCCCCTT 
CATTTGGCAG TGGAGGCCCA GGCAGCCGAT GTGCTGGAGC TTCTCCTGAG GGCAGGCGCG 
AACCCTGCTG CCCGCATGTA CGGTGGCCGC ACCCCACTCG GCAGTGCCAT GCTCCGGCCC 
AACCCCATCC TCGCCCGCCT CCTCCGTGCA CACGGAGCCC CTGAGCCCGA GGGCGAGGAC 
GAGAAATCCG GCCCCTGCAG CAGCAGTAGC GACAGCGACA GCGGAGACGA GGGCGATGAA 
TACGACGACA TTGTGGTTCA CAGCAGCCGC AGCCAAACCC GGCTGCCTCC CACCCCAGCC 
TCAAAACCTC TTCCTGACGA CCCCCGCCCC GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723290.3
CDS	18..1073
Translation	MGAVLKPLRLSPTALSRHQPLCPVTDCSVLSPTALSRDGTRNGSGRDRAQNYNSQQTLRPQTRFRTTPRAPQLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV

Target ORF information:

RefSeq Version	XM_006723227.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor beta (NFKBIB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723227.3

ORF Insert Sequence:

ATGGGCGCGG TGCTGAAGCC CTTGAGGCTG TCACCGACCG CTCTGTCCCG TCACCAACCA 
CTGTGTCCCG TCACCGACTG CTCTGTCCTG TCACCGACTG CTCTGTCCCG TGACGGCACC 
AGAAATGGGA GTGGCCGTGA TAGGGCACAG AACTACAACT CTCAGCAGAC ATTGCGGCCG 
CAGACGCGCT TTCGTACAAC ACCCAGAGCG CCCCAGTTAG GCTTCTCGGC CGGCACTGAG 
TACATGGACC TGCAGAATGA CCTAGGCCAG ACAGCCCTGC ACCTGGCAGC CATCCTGGGG 
GAGACATCCA CGGTGGAGAA GCTGTACGCA GCAGGCGCCG GGCTGTGTGT GGCGGAGCGT 
AGGGGCCACA CGGCGCTGCA CCTGGCCTGC CGTGTGGGGG CACACGCCTG TGCCCGTGCC 
CTGCTTCAGC CCCGCCCCCG GCGCCCCAGG GAAGCCCCCG ACACCTACCT CGCTCAGGGC 
CCTGACCGTA CTCCCGACAC CAACCATACC CCTGTCGCCT TGTACCCCGA TTCCGACTTG 
GAGAAGGAAG AAGAGGAGAG TGAGGAGGAC TGGAAGCTGC AGCTGGAGGC TGAAAACTAC 
GAGGGCCACA CCCCACTCCA CGTGGCCGTT ATCCACAAAG ATGTGGAGAT GGTCCGGCTG 
CTCCGAGATG CTGGAGCTGA CCTTGACAAA CCGGAGCCCA CGTGCGGCCG GAGCCCCCTT 
CATTTGGCAG TGGAGGCCCA GGCAGCCGAT GTGCTGGAGC TTCTCCTGAG GGCAGGCGCG 
AACCCTGCTG CCCGCATGTA CGGTGGCCGC ACCCCACTCG GCAGTGCCAT GCTCCGGCCC 
AACCCCATCC TCGCCCGCCT CCTCCGTGCA CACGGAGCCC CTGAGCCCGA GGGCGAGGAC 
GAGAAATCCG GCCCCTGCAG CAGCAGTAGC GACAGCGACA GCGGAGACGA GGGCGATGAA 
TACGACGACA TTGTGGTTCA CAGCAGCCGC AGCCAAACCC GGCTGCCTCC CACCCCAGCC 
TCAAAACCTC TTCCTGACGA CCCCCGCCCC GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of I?B and Downregulation of Survivin.
Clinical cancer research : an official journal of the American Association for Cancer Research23(15)4301-4311(2017 Aug)
Nair JS,Musi E,Schwartz GK

Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival.
Viruses9(5)(2017 Apr)
Othumpangat S,Bryan NB,Beezhold DH,Noti JD

IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-?B-mediated signalling.
International journal of cancer138(1)160-70(2016 Jan)
Phoon YP,Cheung AK,Cheung FM,Chan KF,Wong S,Wong BW,Tung SY,Yau CC,Ng WT,Lung ML

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Journal of proteome research13(12)5339-46(2014 Dec)
Chen TC,Lin KT,Chen CH,Lee SA,Lee PY,Liu YW,Kuo YL,Wang FS,Lai JM,Huang CY

Genetic polymorphisms and risk of recurrent wheezing in pediatric age.
BMC pulmonary medicine14162(2014 Oct)
Esposito S,Ierardi V,Daleno C,Scala A,Terranova L,Tagliabue C,Rios WP,Pelucchi C,Principi N

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NFKBIB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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