SPANXN4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SPANXN4
Entrez Gene ID	441525
Full Name	SPANX family member N4
Synonyms	CT11.9
General protein information	Preferred Names SPANX family member N4 Names sperm protein associated with the nucleus on the X chromosome N4 cancer/testis antigen family 11, member 9 nuclear-associated protein SPAN-Xn4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq27.3
Summary	This gene represents one of several duplicated family members that are located on the X chromosome. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members. [provided by RefSeq, Sep 2009].
Disorder MIM:	300667

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009613.2	NP_001009613.1	sperm protein associated with the nucleus on the X chromosome N4
XM_017029543.1	XP_016885032.1	sperm protein associated with the nucleus on the X chromosome N4 isoform X1
XM_017029544.1	XP_016885033.1	sperm protein associated with the nucleus on the X chromosome N4 isoform X2
NM_001009613.3	NP_001009613.1	sperm protein associated with the nucleus on the X chromosome N4

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC740280	XP_001139788.1
	LOC697888	XP_001085974.1
Homo sapiens (human)	SPANXN4	NP_001009613.1

Gene Ontology
Bibliography

Related articles in PubMed

Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis.
Westbrook VA, Schoppee PD, Vanage GR, Klotz KL, Diekman AB, Flickinger CJ, Coppola MA, Herr JC
Molecular human reproduction12(11)703-16(2006 Nov)

The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids.
Kouprina N, Mullokandov M, Rogozin IB, Collins NK, Solomon G, Otstot J, Risinger JI, Koonin EV, Barrett JC, Larionov V
Proceedings of the National Academy of Sciences of the United States of America101(9)3077-82(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SPANXN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPANXN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18055	NM_001009613.3 Latest version!	Homo sapiens SPANX family member N4 (SPANXN4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu99315	XM_017029543.1 Latest version!	Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu99316	XM_017029544.1 Latest version!	Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu18055	NM_001009613.2	Homo sapiens SPANX family member N4 (SPANXN4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SPANXN4 ( NM_001009613.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009613.1 Homo sapiens SPANX family member N4 (SPANXN4), mRNA.

Price & Availability↑

CloneID	OHu18055
Clone ID Related Accession (Same CDS sequence)	NM_001009613.2 , NM_001009613.3
Accession Version	NM_001009613.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC130503.1. This sequence is a reference standard in the RefSeqGene project. On Jun 14, 2007 this sequence version replaced NM_001009613.1. ##Evidence-Data-START## Transcript exon combination :: BC130503.1, DQ336126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGTGG GCAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009613.1
CDS	98..397
Translation	MEEPTSSTNENKMKSPCESNKRKVDKKKKNLHRASAPEQSLKETEKAKYPTLVFYCRKNKKRNSNQLENNQPTESSTDPIKEKGDLDISAGSPQDGGQN

Target ORF information:

RefSeq Version	NM_001009613.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N4 (SPANXN4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009613.2

ORF Insert Sequence:

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGTGG GCAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPANXN4 ( NM_001009613.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009613.1 Homo sapiens SPANX family member N4 (SPANXN4), mRNA.

Price & Availability↑

CloneID	OHu18055
Clone ID Related Accession (Same CDS sequence)	NM_001009613.2 , NM_001009613.3
Accession Version	NM_001009613.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC130503.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001009613.2. ##Evidence-Data-START## Transcript exon combination :: BC130505.1, DQ336126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END##

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGTGG GCAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009613.1
CDS	88..387
Translation	MEEPTSSTNENKMKSPCESNKRKVDKKKKNLHRASAPEQSLKETEKAKYPTLVFYCRKNKKRNSNQLENNQPTESSTDPIKEKGDLDISAGSPQDGGQN

Target ORF information:

RefSeq Version	NM_001009613.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N4 (SPANXN4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009613.3

ORF Insert Sequence:

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGTGG GCAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPANXN4 ( XM_017029543.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885032.1 Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99315
Clone ID Related Accession (Same CDS sequence)	XM_017029543.1
Accession Version	XM_017029543.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGAGA GGAAGAAAAG 
GATTTGGTGT TCCTTGGAGC ACGTGCATGT TTAGAAGAGC ACATAAGAAG ATCTGTATTG 
TATGTAGGTG ACAGTGACAC TCTTTCCAAA ATGAAGACAT CAGAATCACC ACCTTCAGGC 
CACATACCTC AGAGTGGTGT GTTTTGTAAC TCACCCAATG CTGTGAGCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885032.1
CDS	88..561
Translation	MEEPTSSTNENKMKSPCESNKRKVDKKKKNLHRASAPEQSLKETEKAKYPTLVFYCRKNKKRNSNQLENNQPTESSTDPIKEKGDLDISAGSPQDGEEEKDLVFLGARACLEEHIRRSVLYVGDSDTLSKMKTSESPPSGHIPQSGVFCNSPNAVSN

Target ORF information:

RefSeq Version	XM_017029543.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029543.1

ORF Insert Sequence:

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAAGAAT CTGCACAGAG CCTCAGCCCC TGAACAGAGT 
TTGAAAGAGA CAGAAAAAGC AAAATATCCA ACATTAGTGT TTTACTGCAG GAAGAATAAG 
AAAAGAAATT CAAATCAACT GGAGAATAAC CAGCCTACAG AGAGCTCCAC TGATCCAATC 
AAAGAGAAAG GAGACCTAGA CATATCTGCA GGATCTCCAC AGGATGGAGA GGAAGAAAAG 
GATTTGGTGT TCCTTGGAGC ACGTGCATGT TTAGAAGAGC ACATAAGAAG ATCTGTATTG 
TATGTAGGTG ACAGTGACAC TCTTTCCAAA ATGAAGACAT CAGAATCACC ACCTTCAGGC 
CACATACCTC AGAGTGGTGT GTTTTGTAAC TCACCCAATG CTGTGAGCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPANXN4 ( XM_017029544.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885033.1 Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu99316
Clone ID Related Accession (Same CDS sequence)	XM_017029544.1
Accession Version	XM_017029544.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAATCTG CACAGAGCCT CAGCCCCTGA ACAGAGTTTG 
AAAGAGACAG AAAAAGCAAA ATATCCAACA TTAGTGTTTT ACTGCAGGAA GAATAAGAAA 
AGAAATTCAA ATCAACTGGA GAATAACCAG CCTACAGAGA GCTCCACTGA TCCAATCAAA 
GAGAAAGGAG ACCTAGACAT ATCTGCAGGA TCTCCACAGG ATGGAGAGGA AGAAAAGGAT 
TTGGTGTTCC TTGGAGCACG TGCATGTTTA GAAGAGCACA TAAGAAGATC TGTATTGTAT 
GTAGGTGACA GTGACACTCT TTCCAAAATG AAGACATCAG AATCACCACC TTCAGGCCAC 
ATACCTCAGA GTGGTGTGTT TTGTAACTCA CCCAATGCTG TGAGCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885033.1
CDS	88..558
Translation	MEEPTSSTNENKMKSPCESNKRKVDKKKNLHRASAPEQSLKETEKAKYPTLVFYCRKNKKRNSNQLENNQPTESSTDPIKEKGDLDISAGSPQDGEEEKDLVFLGARACLEEHIRRSVLYVGDSDTLSKMKTSESPPSGHIPQSGVFCNSPNAVSN

Target ORF information:

RefSeq Version	XM_017029544.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N4 (SPANXN4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029544.1

ORF Insert Sequence:

ATGGAAGAGC CAACTTCCAG CACCAACGAG AATAAAATGA AGAGCCCCTG TGAATCTAAC 
AAAAGAAAAG TTGACAAGAA GAAGAATCTG CACAGAGCCT CAGCCCCTGA ACAGAGTTTG 
AAAGAGACAG AAAAAGCAAA ATATCCAACA TTAGTGTTTT ACTGCAGGAA GAATAAGAAA 
AGAAATTCAA ATCAACTGGA GAATAACCAG CCTACAGAGA GCTCCACTGA TCCAATCAAA 
GAGAAAGGAG ACCTAGACAT ATCTGCAGGA TCTCCACAGG ATGGAGAGGA AGAAAAGGAT 
TTGGTGTTCC TTGGAGCACG TGCATGTTTA GAAGAGCACA TAAGAAGATC TGTATTGTAT 
GTAGGTGACA GTGACACTCT TTCCAAAATG AAGACATCAG AATCACCACC TTCAGGCCAC 
ATACCTCAGA GTGGTGTGTT TTGTAACTCA CCCAATGCTG TGAGCAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis.
Molecular human reproduction12(11)703-16(2006 Nov)
Westbrook VA,Schoppee PD,Vanage GR,Klotz KL,Diekman AB,Flickinger CJ,Coppola MA,Herr JC

The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids.
Proceedings of the National Academy of Sciences of the United States of America101(9)3077-82(2004 Mar)
Kouprina N,Mullokandov M,Rogozin IB,Collins NK,Solomon G,Otstot J,Risinger JI,Koonin EV,Barrett JC,Larionov V

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SPANXN4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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