KRT26 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRT26
Entrez Gene ID	353288
Full Name	keratin 26
Synonyms	CK26,K25,K25IRS2,K26,KRT25B
General protein information	Preferred Names keratin 26 Names keratin, type I cytoskeletal 26 CK-26 K25B cytokeratin-26 keratin 26, type I keratin-25B type I inner root sheath specific keratin 25 irs2 type I inner root sheath-specific keratin-K25irs2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	The protein encoded by this gene is a member of the keratin superfamily. This keratin protein is a type I keratin that is specific for the inner root sheath of the hair follicle. This gene exists in a cluster with other keratin genes on chromosome 17q21. [provided by RefSeq, Jul 2009].
Disorder MIM:	616675

mRNA and Protein(s)

mRNA	Protein	Name
NM_181539.4	NP_853517.2	keratin, type I cytoskeletal 26

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KRT26	XP_523629.1
Mus musculus (house mouse)	Krt26	NP_001028569.2
Canis lupus familiaris (dog)	KRT26	XP_548128.2
Homo sapiens (human)	KRT26	NP_853517.2
Bos taurus (cattle)	KRT26	NP_001092566.1
	KRT26	XP_001100380.1
Rattus norvegicus (Norway rat)	Krt26	NP_001008823.1

Gene Ontology
Bibliography

Related articles in PubMed

K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.
Langbein L, Rogers MA, Praetzel-Wunder S, Helmke B, Schirmacher P, Schweizer J
The Journal of investigative dermatology126(11)2377-86(2006 Nov)

New consensus nomenclature for mammalian keratins.
Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW
The Journal of cell biology174(2)169-74(2006 Jul)

The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.
Rogers MA, Winter H, Langbein L, Bleiler R, Schweizer J
Differentiation; research in biological diversity72(9-10)527-40(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRT26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu19190	NM_181539.4 Latest version!	Homo sapiens keratin 26 (KRT26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRT26 ( NM_181539.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_853517.2 Homo sapiens keratin 26 (KRT26), mRNA.

Price & Availability↑

CloneID	OHu19190
Clone ID Related Accession (Same CDS sequence)	NM_181539.4
Accession Version	NM_181539.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 26
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ564205.2 and BC132951.1. This sequence is a reference standard in the RefSeqGene project. On Jul 24, 2009 this sequence version replaced NM_181539.3. ##Evidence-Data-START## Transcript exon combination :: AJ564205.2, BC132951.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTTTTC GACTTTCTGG TGGATCCAGG AGGATCTGCT CGCGAACTGG GTCTGGTAGG 
CTGTCCGGTG GAGGAACAGG CTTCGTGGCT GGGAATGTGT GTGTTGGATC GGGAGCAAGA 
AGCAGCTTTT CTTGTACTCT TGAGGGCATC TCTTCTGGAG GAAGCTTCTG CAATAGCGGT 
GGAGGGTTGG GAAGTGGTGC CTGTGCTGGT TTTCTTGGCA ATGAGCACAG CCTCCTCTCT 
GGGAATGAAA AGGTGACCAT GCAGAATCTC AACGACCGCC TGGCATCCTA CCTGGACCAT 
GTGCATGCTC TAGAGGAGGC CAACGCAGAC CTGGAGCAGA AGATCAAGGG CTGGTACGAG 
AAATGTGAGC CTGGCTCTTC CCGGGAACAC GATCATGACT ATAGCAGATA CTTCTCAGTC 
ATAGAAGATC TTAAAAGGCA GATTATTTCT GCGACCATCT GCAATGCCAG CATTGTTCTA 
CAAAATGACA ATGCCAGACT GACCGCTGAT GACTTCAGGC TGAAGTATGA AAATGAGCTG 
GCTCTGCACC ACAGTGTTGA GGCCGACACC AGTGGTCTTC GCAGAGTGTT GGATGAACTG 
ACCCTTTGTA CAACCGACCT GGAGATACAG TGTGAGACCC TCAGTGAGGA ATTGACCTAC 
CTCAAAAAAA GTCATGAGGA GGAAATGGAA GTCTTGCAAT ATACAGCTGG GGGGAACGTG 
AACGTGGAGA TGAATGCAAC CCCAGGAGTG GACCTAACTG TCCTGTTGAA CAACATGAGG 
GCTGAGTATG AGGACTTGGC TGAGCAGAAC CGCAAAGATG CTGAAGCCTG GTTCAACGAG 
AGGAGTGCAA CGCTGCAACA ACAGATTTCC GATCATGAGG GAGCAGCCAC AGCAGCCAGA 
AATGAGCTGA CCGAATTAAA ACGCAATCTG CAAACCCTGG AAATAGAACT TCAGTCCCTC 
ATGGCTGTGA AACATTCCTA TGAATGCTCC TTGGCTGAGA CTGAAGGAAA TTACTGCAAT 
CAACTCCAGC AAATTCAGGA TCAGATAGGG GTGATGGAGG AACAACTGCA ACAGATTCGA 
ACAGAAACAG AAGGCCAGAA GCTGGAGTAT GAACAGCTTC TTGATGTAAA AATATTTTTA 
GAAAAAGAAA TTGACATTTA TTGCAACTTA CTAGATGGAG AAGAAAGAAA AAGCAAATCC 
ACATGTTACA AATCAAAAGG ATACAGGCCT GTGAATTCTG GAAATCAAGC CAAAGACTCA 
ACAGAAGAAA CTATTGTTAA AACAGTGGTT GAGGAACTGG ATCAAATTGG CAATCTCCTT 
TCACTGAGAG TCCACTCAGT TGAAGAAAAG TCCTCTAAAA TAAGCAACAT TACAGTAGAG 
CAACGAGTAC CTTCTAAAGC ACCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_853517.2
CDS	47..1453
Translation	MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGWYEKCEPGSSREHDHDYSRYFSVIEDLKRQIISATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP

Target ORF information:

RefSeq Version	NM_181539.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 26 (KRT26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181539.4

ORF Insert Sequence:

ATGTCTTTTC GACTTTCTGG TGGATCCAGG AGGATCTGCT CGCGAACTGG GTCTGGTAGG 
CTGTCCGGTG GAGGAACAGG CTTCGTGGCT GGGAATGTGT GTGTTGGATC GGGAGCAAGA 
AGCAGCTTTT CTTGTACTCT TGAGGGCATC TCTTCTGGAG GAAGCTTCTG CAATAGCGGT 
GGAGGGTTGG GAAGTGGTGC CTGTGCTGGT TTTCTTGGCA ATGAGCACAG CCTCCTCTCT 
GGGAATGAAA AGGTGACCAT GCAGAATCTC AACGACCGCC TGGCATCCTA CCTGGACCAT 
GTGCATGCTC TAGAGGAGGC CAACGCAGAC CTGGAGCAGA AGATCAAGGG CTGGTACGAG 
AAATGTGAGC CTGGCTCTTC CCGGGAACAC GATCATGACT ATAGCAGATA CTTCTCAGTC 
ATAGAAGATC TTAAAAGGCA GATTATTTCT GCGACCATCT GCAATGCCAG CATTGTTCTA 
CAAAATGACA ATGCCAGACT GACCGCTGAT GACTTCAGGC TGAAGTATGA AAATGAGCTG 
GCTCTGCACC ACAGTGTTGA GGCCGACACC AGTGGTCTTC GCAGAGTGTT GGATGAACTG 
ACCCTTTGTA CAACCGACCT GGAGATACAG TGTGAGACCC TCAGTGAGGA ATTGACCTAC 
CTCAAAAAAA GTCATGAGGA GGAAATGGAA GTCTTGCAAT ATACAGCTGG GGGGAACGTG 
AACGTGGAGA TGAATGCAAC CCCAGGAGTG GACCTAACTG TCCTGTTGAA CAACATGAGG 
GCTGAGTATG AGGACTTGGC TGAGCAGAAC CGCAAAGATG CTGAAGCCTG GTTCAACGAG 
AGGAGTGCAA CGCTGCAACA ACAGATTTCC GATCATGAGG GAGCAGCCAC AGCAGCCAGA 
AATGAGCTGA CCGAATTAAA ACGCAATCTG CAAACCCTGG AAATAGAACT TCAGTCCCTC 
ATGGCTGTGA AACATTCCTA TGAATGCTCC TTGGCTGAGA CTGAAGGAAA TTACTGCAAT 
CAACTCCAGC AAATTCAGGA TCAGATAGGG GTGATGGAGG AACAACTGCA ACAGATTCGA 
ACAGAAACAG AAGGCCAGAA GCTGGAGTAT GAACAGCTTC TTGATGTAAA AATATTTTTA 
GAAAAAGAAA TTGACATTTA TTGCAACTTA CTAGATGGAG AAGAAAGAAA AAGCAAATCC 
ACATGTTACA AATCAAAAGG ATACAGGCCT GTGAATTCTG GAAATCAAGC CAAAGACTCA 
ACAGAAGAAA CTATTGTTAA AACAGTGGTT GAGGAACTGG ATCAAATTGG CAATCTCCTT 
TCACTGAGAG TCCACTCAGT TGAAGAAAAG TCCTCTAAAA TAAGCAACAT TACAGTAGAG 
CAACGAGTAC CTTCTAAAGC ACCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.
The Journal of investigative dermatology126(11)2377-86(2006 Nov)
Langbein L,Rogers MA,Praetzel-Wunder S,Helmke B,Schirmacher P,Schweizer J

New consensus nomenclature for mammalian keratins.
The Journal of cell biology174(2)169-74(2006 Jul)
Schweizer J,Bowden PE,Coulombe PA,Langbein L,Lane EB,Magin TM,Maltais L,Omary MB,Parry DA,Rogers MA,Wright MW

The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.
Differentiation; research in biological diversity72(9-10)527-40(2004 Dec)
Rogers MA,Winter H,Langbein L,Bleiler R,Schweizer J