CCN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCN1
Entrez Gene ID	3491
Full Name	cysteine rich angiogenic inducer 61
Synonyms	CCN1,GIG1,IGFBP10
General protein information	Preferred Names cysteine rich angiogenic inducer 61 Names protein CYR61 CCN family member 1 IBP-10 IGF-binding protein 10 IGFBP-10 cysteine-rich heparin-binding protein 61 cysteine-rich, anigogenic inducer, 61 insulin-like growth factor-binding protein 10
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.3
Summary	The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011].
Disorder MIM:	602369

mRNA and Protein(s)

mRNA	Protein	Name
NM_001554.4	NP_001545.2	protein CYR61 precursor
NM_001554.5	NP_001545.2	CCN family member 1 precursor

Pathways from BioSystems

Homologies

	CYR61	XP_001104992.2
Danio rerio (zebrafish)	zgc:85866	NP_001001826.1
Xenopus tropicalis (tropical clawed frog)	cyr61	NP_001098984.1
Canis lupus familiaris (dog)	CYR61	XP_537091.2
Rattus norvegicus (Norway rat)	Cyr61	NP_112617.2
Homo sapiens (human)	CYR61	NP_001545.2
Pan troglodytes (chimpanzee)	CYR61	NP_001092023.1
Mus musculus (house mouse)	Cyr61	NP_034646.1
Bos taurus (cattle)	CYR61	NP_001029512.1
Gallus gallus (chicken)	CYR61	NP_001026734.1

Gene Ontology

The following CCN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19953	NM_001554.5 Latest version!	Homo sapiens cellular communication network factor 1 (CCN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu19953	NM_001554.4	Homo sapiens cysteine rich angiogenic inducer 61 (CYR61), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCN1 ( NM_001554.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001545.2 Homo sapiens cysteine rich angiogenic inducer 61 (CYR61), mRNA.

Price & Availability↑

CloneID	OHu19953
Clone ID Related Accession (Same CDS sequence)	NM_001554.4 , NM_001554.5
Accession Version	NM_001554.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	protein CYR61 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA764894.1, BC009199.2 and BP387218.1. On Aug 28, 2008 this sequence version replaced NM_001554.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314571.1, SRR1803615.101477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTCCC GCATCGCCAG GGCGCTCGCC TTAGTCGTCA CCCTTCTCCA CTTGACCAGG 
CTGGCGCTCT CCACCTGCCC CGCTGCCTGC CACTGCCCCC TGGAGGCGCC CAAGTGCGCG 
CCGGGAGTCG GGCTGGTCCG GGACGGCTGC GGCTGCTGTA AGGTCTGCGC CAAGCAGCTC 
AACGAGGACT GCAGCAAAAC GCAGCCCTGC GACCACACCA AGGGGCTGGA ATGCAACTTC 
GGCGCCAGCT CCACCGCTCT GAAGGGGATC TGCAGAGCTC AGTCAGAGGG CAGACCCTGT 
GAATATAACT CCAGAATCTA CCAAAACGGG GAAAGTTTCC AGCCCAACTG TAAACATCAG 
TGCACATGTA TTGATGGCGC CGTGGGCTGC ATTCCTCTGT GTCCCCAAGA ACTATCTCTC 
CCCAACTTGG GCTGTCCCAA CCCTCGGCTG GTCAAAGTTA CCGGGCAGTG CTGCGAGGAG 
TGGGTCTGTG ACGAGGATAG TATCAAGGAC CCCATGGAGG ACCAGGACGG CCTCCTTGGC 
AAGGAGCTGG GATTCGATGC CTCCGAGGTG GAGTTGACGA GAAACAATGA ATTGATTGCA 
GTTGGAAAAG GCAGCTCACT GAAGCGGCTC CCTGTTTTTG GAATGGAGCC TCGCATCCTA 
TACAACCCTT TACAAGGCCA GAAATGTATT GTTCAAACAA CTTCATGGTC CCAGTGCTCA 
AAGACCTGTG GAACTGGTAT CTCCACACGA GTTACCAATG ACAACCCTGA GTGCCGCCTT 
GTGAAAGAAA CCCGGATTTG TGAGGTGCGG CCTTGTGGAC AGCCAGTGTA CAGCAGCCTG 
AAAAAGGGCA AGAAATGCAG CAAGACCAAG AAATCCCCCG AACCAGTCAG GTTTACTTAC 
GCTGGATGTT TGAGTGTGAA GAAATACCGG CCCAAGTACT GCGGTTCCTG CGTGGACGGC 
CGATGCTGCA CGCCCCAGCT GACCAGGACT GTGAAGATGC GGTTCCGCTG CGAAGATGGG 
GAGACATTTT CCAAGAACGT CATGATGATC CAGTCCTGCA AATGCAACTA CAACTGCCCG 
CATGCCAATG AAGCAGCGTT TCCCTTCTAC AGGCTGTTCA ATGACATTCA CAAATTTAGG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001545.2
CDS	225..1370
Translation	MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD

Target ORF information:

RefSeq Version	NM_001554.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich angiogenic inducer 61 (CYR61), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001554.4

ORF Insert Sequence:

ATGAGCTCCC GCATCGCCAG GGCGCTCGCC TTAGTCGTCA CCCTTCTCCA CTTGACCAGG 
CTGGCGCTCT CCACCTGCCC CGCTGCCTGC CACTGCCCCC TGGAGGCGCC CAAGTGCGCG 
CCGGGAGTCG GGCTGGTCCG GGACGGCTGC GGCTGCTGTA AGGTCTGCGC CAAGCAGCTC 
AACGAGGACT GCAGCAAAAC GCAGCCCTGC GACCACACCA AGGGGCTGGA ATGCAACTTC 
GGCGCCAGCT CCACCGCTCT GAAGGGGATC TGCAGAGCTC AGTCAGAGGG CAGACCCTGT 
GAATATAACT CCAGAATCTA CCAAAACGGG GAAAGTTTCC AGCCCAACTG TAAACATCAG 
TGCACATGTA TTGATGGCGC CGTGGGCTGC ATTCCTCTGT GTCCCCAAGA ACTATCTCTC 
CCCAACTTGG GCTGTCCCAA CCCTCGGCTG GTCAAAGTTA CCGGGCAGTG CTGCGAGGAG 
TGGGTCTGTG ACGAGGATAG TATCAAGGAC CCCATGGAGG ACCAGGACGG CCTCCTTGGC 
AAGGAGCTGG GATTCGATGC CTCCGAGGTG GAGTTGACGA GAAACAATGA ATTGATTGCA 
GTTGGAAAAG GCAGCTCACT GAAGCGGCTC CCTGTTTTTG GAATGGAGCC TCGCATCCTA 
TACAACCCTT TACAAGGCCA GAAATGTATT GTTCAAACAA CTTCATGGTC CCAGTGCTCA 
AAGACCTGTG GAACTGGTAT CTCCACACGA GTTACCAATG ACAACCCTGA GTGCCGCCTT 
GTGAAAGAAA CCCGGATTTG TGAGGTGCGG CCTTGTGGAC AGCCAGTGTA CAGCAGCCTG 
AAAAAGGGCA AGAAATGCAG CAAGACCAAG AAATCCCCCG AACCAGTCAG GTTTACTTAC 
GCTGGATGTT TGAGTGTGAA GAAATACCGG CCCAAGTACT GCGGTTCCTG CGTGGACGGC 
CGATGCTGCA CGCCCCAGCT GACCAGGACT GTGAAGATGC GGTTCCGCTG CGAAGATGGG 
GAGACATTTT CCAAGAACGT CATGATGATC CAGTCCTGCA AATGCAACTA CAACTGCCCG 
CATGCCAATG AAGCAGCGTT TCCCTTCTAC AGGCTGTTCA ATGACATTCA CAAATTTAGG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCN1 ( NM_001554.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001545.2 Homo sapiens cellular communication network factor 1 (CCN1), mRNA.

Price & Availability↑

CloneID	OHu19953
Clone ID Related Accession (Same CDS sequence)	NM_001554.4 , NM_001554.5
Accession Version	NM_001554.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	CCN family member 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA764894.1, BC009199.2 and BP387218.1. On Nov 23, 2018 this sequence version replaced NM_001554.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314571.1, SRR1803615.101477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000451137.7/ ENSP00000398736.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCTCCC GCATCGCCAG GGCGCTCGCC TTAGTCGTCA CCCTTCTCCA CTTGACCAGG 
CTGGCGCTCT CCACCTGCCC CGCTGCCTGC CACTGCCCCC TGGAGGCGCC CAAGTGCGCG 
CCGGGAGTCG GGCTGGTCCG GGACGGCTGC GGCTGCTGTA AGGTCTGCGC CAAGCAGCTC 
AACGAGGACT GCAGCAAAAC GCAGCCCTGC GACCACACCA AGGGGCTGGA ATGCAACTTC 
GGCGCCAGCT CCACCGCTCT GAAGGGGATC TGCAGAGCTC AGTCAGAGGG CAGACCCTGT 
GAATATAACT CCAGAATCTA CCAAAACGGG GAAAGTTTCC AGCCCAACTG TAAACATCAG 
TGCACATGTA TTGATGGCGC CGTGGGCTGC ATTCCTCTGT GTCCCCAAGA ACTATCTCTC 
CCCAACTTGG GCTGTCCCAA CCCTCGGCTG GTCAAAGTTA CCGGGCAGTG CTGCGAGGAG 
TGGGTCTGTG ACGAGGATAG TATCAAGGAC CCCATGGAGG ACCAGGACGG CCTCCTTGGC 
AAGGAGCTGG GATTCGATGC CTCCGAGGTG GAGTTGACGA GAAACAATGA ATTGATTGCA 
GTTGGAAAAG GCAGCTCACT GAAGCGGCTC CCTGTTTTTG GAATGGAGCC TCGCATCCTA 
TACAACCCTT TACAAGGCCA GAAATGTATT GTTCAAACAA CTTCATGGTC CCAGTGCTCA 
AAGACCTGTG GAACTGGTAT CTCCACACGA GTTACCAATG ACAACCCTGA GTGCCGCCTT 
GTGAAAGAAA CCCGGATTTG TGAGGTGCGG CCTTGTGGAC AGCCAGTGTA CAGCAGCCTG 
AAAAAGGGCA AGAAATGCAG CAAGACCAAG AAATCCCCCG AACCAGTCAG GTTTACTTAC 
GCTGGATGTT TGAGTGTGAA GAAATACCGG CCCAAGTACT GCGGTTCCTG CGTGGACGGC 
CGATGCTGCA CGCCCCAGCT GACCAGGACT GTGAAGATGC GGTTCCGCTG CGAAGATGGG 
GAGACATTTT CCAAGAACGT CATGATGATC CAGTCCTGCA AATGCAACTA CAACTGCCCG 
CATGCCAATG AAGCAGCGTT TCCCTTCTAC AGGCTGTTCA ATGACATTCA CAAATTTAGG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001545.2
CDS	225..1370
Translation	MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD

Target ORF information:

RefSeq Version	NM_001554.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cellular communication network factor 1 (CCN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001554.5

ORF Insert Sequence:

ATGAGCTCCC GCATCGCCAG GGCGCTCGCC TTAGTCGTCA CCCTTCTCCA CTTGACCAGG 
CTGGCGCTCT CCACCTGCCC CGCTGCCTGC CACTGCCCCC TGGAGGCGCC CAAGTGCGCG 
CCGGGAGTCG GGCTGGTCCG GGACGGCTGC GGCTGCTGTA AGGTCTGCGC CAAGCAGCTC 
AACGAGGACT GCAGCAAAAC GCAGCCCTGC GACCACACCA AGGGGCTGGA ATGCAACTTC 
GGCGCCAGCT CCACCGCTCT GAAGGGGATC TGCAGAGCTC AGTCAGAGGG CAGACCCTGT 
GAATATAACT CCAGAATCTA CCAAAACGGG GAAAGTTTCC AGCCCAACTG TAAACATCAG 
TGCACATGTA TTGATGGCGC CGTGGGCTGC ATTCCTCTGT GTCCCCAAGA ACTATCTCTC 
CCCAACTTGG GCTGTCCCAA CCCTCGGCTG GTCAAAGTTA CCGGGCAGTG CTGCGAGGAG 
TGGGTCTGTG ACGAGGATAG TATCAAGGAC CCCATGGAGG ACCAGGACGG CCTCCTTGGC 
AAGGAGCTGG GATTCGATGC CTCCGAGGTG GAGTTGACGA GAAACAATGA ATTGATTGCA 
GTTGGAAAAG GCAGCTCACT GAAGCGGCTC CCTGTTTTTG GAATGGAGCC TCGCATCCTA 
TACAACCCTT TACAAGGCCA GAAATGTATT GTTCAAACAA CTTCATGGTC CCAGTGCTCA 
AAGACCTGTG GAACTGGTAT CTCCACACGA GTTACCAATG ACAACCCTGA GTGCCGCCTT 
GTGAAAGAAA CCCGGATTTG TGAGGTGCGG CCTTGTGGAC AGCCAGTGTA CAGCAGCCTG 
AAAAAGGGCA AGAAATGCAG CAAGACCAAG AAATCCCCCG AACCAGTCAG GTTTACTTAC 
GCTGGATGTT TGAGTGTGAA GAAATACCGG CCCAAGTACT GCGGTTCCTG CGTGGACGGC 
CGATGCTGCA CGCCCCAGCT GACCAGGACT GTGAAGATGC GGTTCCGCTG CGAAGATGGG 
GAGACATTTT CCAAGAACGT CATGATGATC CAGTCCTGCA AATGCAACTA CAACTGCCCG 
CATGCCAATG AAGCAGCGTT TCCCTTCTAC AGGCTGTTCA ATGACATTCA CAAATTTAGG 
GACTAA