CD2AP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CD2AP
Entrez Gene ID	23607
Full Name	CD2 associated protein
Synonyms	CMS
General protein information	Preferred Names CD2 associated protein Names CD2-associated protein Cas ligand with multiple Src homology 3 (SH3) domains adapter protein CMS cas ligand with multiple SH3 domains
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p12.3
Summary	This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008].
Disorder MIM:	604241
Disorder Html:	Glomerulosclerosis, focal segmental, 3, 607832 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_012120.2	NP_036252.1	CD2-associated protein
NM_012120.3	NP_036252.1	CD2-associated protein
XM_017010641.1	XP_016866130.1	CD2-associated protein isoform X3
XM_005248976.1	XP_005249033.1	CD2-associated protein isoform X1
XM_011514449.2	XP_011512751.1	CD2-associated protein isoform X2

Pathways from BioSystems

Homologies

	CD2AP	XP_001103871.1
Gallus gallus (chicken)	CD2AP	XP_003641109.2
Homo sapiens (human)	CD2AP	NP_036252.1
Pan troglodytes (chimpanzee)	CD2AP	XP_527616.2
Canis lupus familiaris (dog)	CD2AP	XP_532162.3
Mus musculus (house mouse)	Cd2ap	NP_033977.3
Bos taurus (cattle)	CD2AP	NP_001193468.1
Danio rerio (zebrafish)	cd2ap	NP_001008583.2
Rattus norvegicus (Norway rat)	Cd2ap	NP_852140.1
Xenopus tropicalis (tropical clawed frog)	cd2ap	NP_001121435.1

Gene Ontology
Bibliography

Related articles in PubMed

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.
Cummins TD, Wu KZL, Bozatzi P, Dingwell KS, Macartney TJ, Wood NT, Varghese J, Gourlay R, Campbell DG, Prescott A, Griffis E, Smith JC, Sapkota GP
Journal of cell science131(1)(2018 Jan)

Decreased gene expression of CD2AP in Chinese patients with sporadic Alzheimer's disease.
Tao QQ, Liu ZJ, Sun YM, Li HL, Yang P, Liu DS, Jiang B, Li XY, Xu JF, Wu ZY
Neurobiology of aging56212.e5-212.e10(2017 Aug)

Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.
Schaefer A, van Duijn TJ, Majolee J, Burridge K, Hordijk PL
Journal of immunology (Baltimore, Md. : 1950)198(12)4823-4836(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CD2AP is an sporadic-Alzheimer's-disease risk gene in a southern Chinese Han population.
Title: Decreased gene expression of CD2AP in Chinese patients with sporadic Alzheimer's disease.

data suggest that CD2AP acts as a negative regulator of ICAM-1 clustering, which limits the formation of ICAM-1 adhesion complexes to prevent uncontrolled neutrophil adhesion and transcellular transmigration.
Title: Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.

Silencing Cindr in nephrocytes led to dramatic nephrocyte functional impairment and shortened life span, as well as collapse of nephrocyte lacunar channels and effacement of nephrocyte slit diaphragms. These phenotypes could be rescued by expression of a wild-type human CD2AP gene, but not a mutant allele derived from a patient with CD2AP-associated NS.
Title: A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome.

CD2AP expression in renal tubules may histologically associate with tissue hypoxia and reflected recovery from CsA-mediated renal injury in nephrotic syndrome patients.
Title: Cyclosporine A induced histological changes of Cathepsin L and CD2AP expression in renal glomeruli and tubules.

data thus reveal a Golgi-traversing pathway for exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively.
Title: Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex.

The following CD2AP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD2AP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18393	NM_012120.3 Latest version!	Homo sapiens CD2 associated protein (CD2AP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu40240	XM_005248976.1 Latest version!	Homo sapiens CD2 associated protein (CD2AP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu66357	XM_011514449.2 Latest version!	Homo sapiens CD2 associated protein (CD2AP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu96497	XM_017010641.1 Latest version!	Homo sapiens CD2 associated protein (CD2AP), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu18393	NM_012120.2	Homo sapiens CD2 associated protein (CD2AP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CD2AP ( NM_012120.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036252.1 Homo sapiens CD2 associated protein (CD2AP), mRNA.

Price & Availability↑

CloneID	OHu18393
Clone ID Related Accession (Same CDS sequence)	NM_012120.2 , NM_012120.3
Accession Version	NM_012120.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1920bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-19
Organism	Homo sapiens(human)
Product	CD2-associated protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA040834.1, AL355353.23, BC069444.1, AL358178.14, AL356421.10 and BU679191.1. This sequence is a reference standard in the RefSeqGene project. On Feb 16, 2007 this sequence version replaced NM_012120.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.200483.1, SRR1660807.6602.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATG TTGTAAATTT TGATGACATA 
GCTTCCTCAG AAAACTTGCT TCATCTCACT GCAAATAGAC CAAAGATGCC TGGAAGAAGG 
TTGCCGGGCC GTTTCAATGG TGGACATTCT CCAACTCACA GCCCCGAAAA AATCTTGAAG 
TTACCAAAAG AAGAAGACAG TGCCAACCTG AAGCCATCTG AATTAAAAAA AGATACATGC 
TACTCTCCAA AGCCATCTGT GTACCTTTCA ACACCTTCCA GTGCTTCTAA AGCAAATACA 
ACTGCTTTCC TGACTCCATT AGAAATCAAA GCTAAAGTGG AAACAGATGA TGTGAAAAAA 
AATTCCCTGG ATGAACTTAG AGCCCAGATT ATTGAATTGT TGTGCATTGT AGAAGCACTG 
AAAAAGGATC ACGGGAAAGA ACTGGAAAAA CTGCGAAAAG ATTTGGAAGA AGAGAAGACA 
ATGAGAAGTA ATCTAGAGAT GGAAATAGAG AAGCTGAAAA AAGCTGTCCT GTCTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036252.1
CDS	457..2376
Translation	MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS

Target ORF information:

RefSeq Version	NM_012120.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CD2 associated protein (CD2AP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012120.2

ORF Insert Sequence:

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATG TTGTAAATTT TGATGACATA 
GCTTCCTCAG AAAACTTGCT TCATCTCACT GCAAATAGAC CAAAGATGCC TGGAAGAAGG 
TTGCCGGGCC GTTTCAATGG TGGACATTCT CCAACTCACA GCCCCGAAAA AATCTTGAAG 
TTACCAAAAG AAGAAGACAG TGCCAACCTG AAGCCATCTG AATTAAAAAA AGATACATGC 
TACTCTCCAA AGCCATCTGT GTACCTTTCA ACACCTTCCA GTGCTTCTAA AGCAAATACA 
ACTGCTTTCC TGACTCCATT AGAAATCAAA GCTAAAGTGG AAACAGATGA TGTGAAAAAA 
AATTCCCTGG ATGAACTTAG AGCCCAGATT ATTGAATTGT TGTGCATTGT AGAAGCACTG 
AAAAAGGATC ACGGGAAAGA ACTGGAAAAA CTGCGAAAAG ATTTGGAAGA AGAGAAGACA 
ATGAGAAGTA ATCTAGAGAT GGAAATAGAG AAGCTGAAAA AAGCTGTCCT GTCTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD2AP ( NM_012120.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036252.1 Homo sapiens CD2 associated protein (CD2AP), mRNA.

Price & Availability↑

CloneID	OHu18393
Clone ID Related Accession (Same CDS sequence)	NM_012120.2 , NM_012120.3
Accession Version	NM_012120.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1920bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	CD2-associated protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA040834.1, AL355353.23, BC069444.1, AL358178.14, AL356421.10 and BU679191.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_012120.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.200483.1, SRR1660807.6602.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000359314.5/ ENSP00000352264.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATG TTGTAAATTT TGATGACATA 
GCTTCCTCAG AAAACTTGCT TCATCTCACT GCAAATAGAC CAAAGATGCC TGGAAGAAGG 
TTGCCGGGCC GTTTCAATGG TGGACATTCT CCAACTCACA GCCCCGAAAA AATCTTGAAG 
TTACCAAAAG AAGAAGACAG TGCCAACCTG AAGCCATCTG AATTAAAAAA AGATACATGC 
TACTCTCCAA AGCCATCTGT GTACCTTTCA ACACCTTCCA GTGCTTCTAA AGCAAATACA 
ACTGCTTTCC TGACTCCATT AGAAATCAAA GCTAAAGTGG AAACAGATGA TGTGAAAAAA 
AATTCCCTGG ATGAACTTAG AGCCCAGATT ATTGAATTGT TGTGCATTGT AGAAGCACTG 
AAAAAGGATC ACGGGAAAGA ACTGGAAAAA CTGCGAAAAG ATTTGGAAGA AGAGAAGACA 
ATGAGAAGTA ATCTAGAGAT GGAAATAGAG AAGCTGAAAA AAGCTGTCCT GTCTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036252.1
CDS	457..2376
Translation	MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS

Target ORF information:

RefSeq Version	NM_012120.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CD2 associated protein (CD2AP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012120.3

ORF Insert Sequence:

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATG TTGTAAATTT TGATGACATA 
GCTTCCTCAG AAAACTTGCT TCATCTCACT GCAAATAGAC CAAAGATGCC TGGAAGAAGG 
TTGCCGGGCC GTTTCAATGG TGGACATTCT CCAACTCACA GCCCCGAAAA AATCTTGAAG 
TTACCAAAAG AAGAAGACAG TGCCAACCTG AAGCCATCTG AATTAAAAAA AGATACATGC 
TACTCTCCAA AGCCATCTGT GTACCTTTCA ACACCTTCCA GTGCTTCTAA AGCAAATACA 
ACTGCTTTCC TGACTCCATT AGAAATCAAA GCTAAAGTGG AAACAGATGA TGTGAAAAAA 
AATTCCCTGG ATGAACTTAG AGCCCAGATT ATTGAATTGT TGTGCATTGT AGAAGCACTG 
AAAAAGGATC ACGGGAAAGA ACTGGAAAAA CTGCGAAAAG ATTTGGAAGA AGAGAAGACA 
ATGAGAAGTA ATCTAGAGAT GGAAATAGAG AAGCTGAAAA AAGCTGTCCT GTCTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD2AP ( XM_005248976.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249033.1 Homo sapiens CD2 associated protein (CD2AP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40240
Clone ID Related Accession (Same CDS sequence)	XM_005248976.1
Accession Version	XM_005248976.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	CD2-associated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGCTAA AGAATATTGT AGAACATTAT TTGCCTATGA AGGTACTAAT 
GAAGATGAAC TTACTTTTAA AGAGGGGGAG ATAATCCATT TGATAAGTAA GGAGACTGGA 
GAAGCTGGCT GGTGGAGGGG CGAACTTAAT GGTAAAGAAG GAGTATTTCC AGACAATTTT 
GCTGTCCAGA TAAATGAACT TGATAAAGAC TTTCCAAAAC CAAAGAAACC ACCACCTCCT 
GCTAAGGCTC CAGCTCCAAA GCCTGAACTG ATAGCTGCAG AGAAGAAATA TTTTTCTTTA 
AAGCCTGAAG AAAAGGATGA AAAATCAACA CTGGAACAGA AACCTTCTAA ACCAGCAGCT 
CCACAAGTCC CACCCAAGAA ACCTACTCCA CCTACCAAAG CCAGTAATTT ACTGAGATCT 
TCTGGAACAG TGTACCCAAA GCGACCTGAA AAACCAGTTC CTCCACCACC TCCTATAGCC 
AAGATTAATG GGGAAGTTTC TAGCATTTCA TCAAAATTTG AAACTGAGCC AGTATCAAAA 
CTAAAGCTAG ATTCTGAACA GCTGCCCCTT AGACCAAAAT CAGTAGACTT TGATTCACTT 
ACAGTAAGGA CCTCCAAAGA AACAGATGTT GTAAATTTTG ATGACATAGC TTCCTCAGAA 
AACTTGCTTC ATCTCACTGC AAATAGACCA AAGATGCCTG GAAGAAGGTT GCCGGGCCGT 
TTCAATGGTG GACATTCTCC AACTCACAGC CCCGAAAAAA TCTTGAAGTT ACCAAAAGAA 
GAAGACAGTG CCAACCTGAA GCCATCTGAA TTAAAAAAAG ATACATGCTA CTCTCCAAAG 
CCATCTGTGT ACCTTTCAAC ACCTTCCAGT GCTTCTAAAG CAAATACAAC TGCTTTCCTG 
ACTCCATTAG AAATCAAAGC TAAAGTGGAA ACAGATGATG TGAAAAAAAA TTCCCTGGAT 
GAACTTAGAG CCCAGATTAT TGAATTGTTG TGCATTGTAG AAGCACTGAA AAAGGATCAC 
GGGAAAGAAC TGGAAAAACT GCGAAAAGAT TTGGAAGAAG AGAAGACAAT GAGAAGTAAT 
CTAGAGATGG AAATAGAGAA GCTGAAAAAA GCTGTCCTGT CTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249033.1
CDS	500..2407
Translation	MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS

Target ORF information:

RefSeq Version	XM_005248976.1
Organism	Homo sapiens(human)
Definition	Homo sapiens CD2 associated protein (CD2AP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248976.1

ORF Insert Sequence:

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGCTAA AGAATATTGT AGAACATTAT TTGCCTATGA AGGTACTAAT 
GAAGATGAAC TTACTTTTAA AGAGGGGGAG ATAATCCATT TGATAAGTAA GGAGACTGGA 
GAAGCTGGCT GGTGGAGGGG CGAACTTAAT GGTAAAGAAG GAGTATTTCC AGACAATTTT 
GCTGTCCAGA TAAATGAACT TGATAAAGAC TTTCCAAAAC CAAAGAAACC ACCACCTCCT 
GCTAAGGCTC CAGCTCCAAA GCCTGAACTG ATAGCTGCAG AGAAGAAATA TTTTTCTTTA 
AAGCCTGAAG AAAAGGATGA AAAATCAACA CTGGAACAGA AACCTTCTAA ACCAGCAGCT 
CCACAAGTCC CACCCAAGAA ACCTACTCCA CCTACCAAAG CCAGTAATTT ACTGAGATCT 
TCTGGAACAG TGTACCCAAA GCGACCTGAA AAACCAGTTC CTCCACCACC TCCTATAGCC 
AAGATTAATG GGGAAGTTTC TAGCATTTCA TCAAAATTTG AAACTGAGCC AGTATCAAAA 
CTAAAGCTAG ATTCTGAACA GCTGCCCCTT AGACCAAAAT CAGTAGACTT TGATTCACTT 
ACAGTAAGGA CCTCCAAAGA AACAGATGTT GTAAATTTTG ATGACATAGC TTCCTCAGAA 
AACTTGCTTC ATCTCACTGC AAATAGACCA AAGATGCCTG GAAGAAGGTT GCCGGGCCGT 
TTCAATGGTG GACATTCTCC AACTCACAGC CCCGAAAAAA TCTTGAAGTT ACCAAAAGAA 
GAAGACAGTG CCAACCTGAA GCCATCTGAA TTAAAAAAAG ATACATGCTA CTCTCCAAAG 
CCATCTGTGT ACCTTTCAAC ACCTTCCAGT GCTTCTAAAG CAAATACAAC TGCTTTCCTG 
ACTCCATTAG AAATCAAAGC TAAAGTGGAA ACAGATGATG TGAAAAAAAA TTCCCTGGAT 
GAACTTAGAG CCCAGATTAT TGAATTGTTG TGCATTGTAG AAGCACTGAA AAAGGATCAC 
GGGAAAGAAC TGGAAAAACT GCGAAAAGAT TTGGAAGAAG AGAAGACAAT GAGAAGTAAT 
CTAGAGATGG AAATAGAGAA GCTGAAAAAA GCTGTCCTGT CTTCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD2AP ( XM_011514449.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512751.1 Homo sapiens CD2 associated protein (CD2AP), transcript variant X2, mRNA.

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CloneID	OHu66357
Clone ID Related Accession (Same CDS sequence)	XM_011514449.2
Accession Version	XM_011514449.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	CD2-associated protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514449.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATATCAA AAGAGAAGGA AATTAAAAGA GAGACGGAAT TCAAGGATGA CAGTTTGCCC 
ATCAAACGGG AAAGGCATGG GAATGTAGCA AGTCTTGTAC AACGAATAAG CACCTATGGA 
CTTCCAGCTG GAGGAATTCA GCCACATCCA CAAACCAAAA ACATTAAGAA GAAGACCAAG 
AAGCGTCAGT GTAAAGTTCT TTTTGAGTAC ATTCCACAAA ATGAGGATGA ACTGGAGCTG 
AAAGTGGGAG ATATTATTGA TATTAATGAA GAGGTAGAAG AAGGCTGGTG GAGTGGAACC 
CTGAATAACA AGTTGGGACT GTTTCCCTCA AATTTTGTGA AAGAATTAGA GGTAACAGAT 
GATGGTGAAA CTCATGAAGC CCAGGACGAT TCAGAAACTG TTTTGGCTGG GCCTACTTCA 
CCTATACCTT CTCTGGGAAA TGTGAGTGAA ACTGCATCTG GATCAGTTAC ACAGCCAAAG 
AAAATTCGAG GAATTGGATT TGGAGACATT TTTAAAGAAG GCTCTGTGAA ACTTCGGACA 
AGAACATCCA GTAGTGAAAC AGAAGAGAAA AAACCAGAAA AGCCCTTAAT CCTACAGTCA 
CTGGGACCCA AAACTCAGAG TGTGGAGATA ACAAAAACAG ATACCGAAGG TAAAATTAAA 
GCTAAAGAAT ATTGTAGAAC ATTATTTGCC TATGAAGGTA CTAATGAAGA TGAACTTACT 
TTTAAAGAGG GGGAGATAAT CCATTTGATA AGTAAGGAGA CTGGAGAAGC TGGCTGGTGG 
AGGGGCGAAC TTAATGGTAA AGAAGGAGTA TTTCCAGACA ATTTTGCTGT CCAGATAAAT 
GAACTTGATA AAGACTTTCC AAAACCAAAG AAACCACCAC CTCCTGCTAA GGCTCCAGCT 
CCAAAGCCTG AACTGATAGC TGCAGAGAAG AAATATTTTT CTTTAAAGCC TGAAGAAAAG 
GATGAAAAAT CAACACTGGA ACAGAAACCT TCTAAACCAG CAGCTCCACA AGTCCCACCC 
AAGAAACCTA CTCCACCTAC CAAAGCCAGT AATTTACTGA GATCTTCTGG AACAGTGTAC 
CCAAAGCGAC CTGAAAAACC AGTTCCTCCA CCACCTCCTA TAGCCAAGAT TAATGGGGAA 
GTTTCTAGCA TTTCATCAAA ATTTGAAACT GAGCCAGTAT CAAAACTAAA GCTAGATTCT 
GAACAGCTGC CCCTTAGACC AAAATCAGTA GACTTTGATT CACTTACAGT AAGGACCTCC 
AAAGAAACAG ATGTTGTAAA TTTTGATGAC ATAGCTTCCT CAGAAAACTT GCTTCATCTC 
ACTGCAAATA GACCAAAGAT GCCTGGAAGA AGGTTGCCGG GCCGTTTCAA TGGTGGACAT 
TCTCCAACTC ACAGCCCCGA AAAAATCTTG AAGTTACCAA AAGAAGAAGA CAGTGCCAAC 
CTGAAGCCAT CTGAATTAAA AAAAGATACA TGCTACTCTC CAAAGCCATC TGTGTACCTT 
TCAACACCTT CCAGTGCTTC TAAAGCAAAT ACAACTGCTT TCCTGACTCC ATTAGAAATC 
AAAGCTAAAG TGGAAACAGA TGATGTGAAA AAAAATTCCC TGGATGAACT TAGAGCCCAG 
ATTATTGAAT TGTTGTGCAT TGTAGAAGCA CTGAAAAAGG ATCACGGGAA AGAACTGGAA 
AAACTGCGAA AAGATTTGGA AGAAGAGAAG ACAATGAGAA GTAATCTAGA GATGGAAATA 
GAGAAGCTGA AAAAAGCTGT CCTGTCTTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512751.1
CDS	226..1998
Translation	MISKEKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS

Target ORF information:

RefSeq Version	XM_011514449.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CD2 associated protein (CD2AP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514449.2

ORF Insert Sequence:

ATGATATCAA AAGAGAAGGA AATTAAAAGA GAGACGGAAT TCAAGGATGA CAGTTTGCCC 
ATCAAACGGG AAAGGCATGG GAATGTAGCA AGTCTTGTAC AACGAATAAG CACCTATGGA 
CTTCCAGCTG GAGGAATTCA GCCACATCCA CAAACCAAAA ACATTAAGAA GAAGACCAAG 
AAGCGTCAGT GTAAAGTTCT TTTTGAGTAC ATTCCACAAA ATGAGGATGA ACTGGAGCTG 
AAAGTGGGAG ATATTATTGA TATTAATGAA GAGGTAGAAG AAGGCTGGTG GAGTGGAACC 
CTGAATAACA AGTTGGGACT GTTTCCCTCA AATTTTGTGA AAGAATTAGA GGTAACAGAT 
GATGGTGAAA CTCATGAAGC CCAGGACGAT TCAGAAACTG TTTTGGCTGG GCCTACTTCA 
CCTATACCTT CTCTGGGAAA TGTGAGTGAA ACTGCATCTG GATCAGTTAC ACAGCCAAAG 
AAAATTCGAG GAATTGGATT TGGAGACATT TTTAAAGAAG GCTCTGTGAA ACTTCGGACA 
AGAACATCCA GTAGTGAAAC AGAAGAGAAA AAACCAGAAA AGCCCTTAAT CCTACAGTCA 
CTGGGACCCA AAACTCAGAG TGTGGAGATA ACAAAAACAG ATACCGAAGG TAAAATTAAA 
GCTAAAGAAT ATTGTAGAAC ATTATTTGCC TATGAAGGTA CTAATGAAGA TGAACTTACT 
TTTAAAGAGG GGGAGATAAT CCATTTGATA AGTAAGGAGA CTGGAGAAGC TGGCTGGTGG 
AGGGGCGAAC TTAATGGTAA AGAAGGAGTA TTTCCAGACA ATTTTGCTGT CCAGATAAAT 
GAACTTGATA AAGACTTTCC AAAACCAAAG AAACCACCAC CTCCTGCTAA GGCTCCAGCT 
CCAAAGCCTG AACTGATAGC TGCAGAGAAG AAATATTTTT CTTTAAAGCC TGAAGAAAAG 
GATGAAAAAT CAACACTGGA ACAGAAACCT TCTAAACCAG CAGCTCCACA AGTCCCACCC 
AAGAAACCTA CTCCACCTAC CAAAGCCAGT AATTTACTGA GATCTTCTGG AACAGTGTAC 
CCAAAGCGAC CTGAAAAACC AGTTCCTCCA CCACCTCCTA TAGCCAAGAT TAATGGGGAA 
GTTTCTAGCA TTTCATCAAA ATTTGAAACT GAGCCAGTAT CAAAACTAAA GCTAGATTCT 
GAACAGCTGC CCCTTAGACC AAAATCAGTA GACTTTGATT CACTTACAGT AAGGACCTCC 
AAAGAAACAG ATGTTGTAAA TTTTGATGAC ATAGCTTCCT CAGAAAACTT GCTTCATCTC 
ACTGCAAATA GACCAAAGAT GCCTGGAAGA AGGTTGCCGG GCCGTTTCAA TGGTGGACAT 
TCTCCAACTC ACAGCCCCGA AAAAATCTTG AAGTTACCAA AAGAAGAAGA CAGTGCCAAC 
CTGAAGCCAT CTGAATTAAA AAAAGATACA TGCTACTCTC CAAAGCCATC TGTGTACCTT 
TCAACACCTT CCAGTGCTTC TAAAGCAAAT ACAACTGCTT TCCTGACTCC ATTAGAAATC 
AAAGCTAAAG TGGAAACAGA TGATGTGAAA AAAAATTCCC TGGATGAACT TAGAGCCCAG 
ATTATTGAAT TGTTGTGCAT TGTAGAAGCA CTGAAAAAGG ATCACGGGAA AGAACTGGAA 
AAACTGCGAA AAGATTTGGA AGAAGAGAAG ACAATGAGAA GTAATCTAGA GATGGAAATA 
GAGAAGCTGA AAAAAGCTGT CCTGTCTTCT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CD2AP ( XM_017010641.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866130.1 Homo sapiens CD2 associated protein (CD2AP), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu96497
Clone ID Related Accession (Same CDS sequence)	XM_017010641.1
Accession Version	XM_017010641.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	CD2-associated protein isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATT TTGTTTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866130.1
CDS	500..1930
Translation	MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDFVS

Target ORF information:

RefSeq Version	XM_017010641.1
Organism	Homo sapiens(human)
Definition	Homo sapiens CD2 associated protein (CD2AP), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010641.1

ORF Insert Sequence:

ATGGTTGACT ATATTGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 
CGAGTTGGAG AAATCATCAG GAATGTGAAA AAGCTACAGG AGGAAGGGTG GCTGGAAGGA 
GAACTAAATG GGAGAAGAGG AATGTTCCCT GACAATTTCG TTAAGGAAAT TAAAAGAGAG 
ACGGAATTCA AGGATGACAG TTTGCCCATC AAACGGGAAA GGCATGGGAA TGTAGCAAGT 
CTTGTACAAC GAATAAGCAC CTATGGACTT CCAGCTGGAG GAATTCAGCC ACATCCACAA 
ACCAAAAACA TTAAGAAGAA GACCAAGAAG CGTCAGTGTA AAGTTCTTTT TGAGTACATT 
CCACAAAATG AGGATGAACT GGAGCTGAAA GTGGGAGATA TTATTGATAT TAATGAAGAG 
GTAGAAGAAG GCTGGTGGAG TGGAACCCTG AATAACAAGT TGGGACTGTT TCCCTCAAAT 
TTTGTGAAAG AATTAGAGGT AACAGATGAT GGTGAAACTC ATGAAGCCCA GGACGATTCA 
GAAACTGTTT TGGCTGGGCC TACTTCACCT ATACCTTCTC TGGGAAATGT GAGTGAAACT 
GCATCTGGAT CAGTTACACA GCCAAAGAAA ATTCGAGGAA TTGGATTTGG AGACATTTTT 
AAAGAAGGCT CTGTGAAACT TCGGACAAGA ACATCCAGTA GTGAAACAGA AGAGAAAAAA 
CCAGAAAAGC CCTTAATCCT ACAGTCACTG GGACCCAAAA CTCAGAGTGT GGAGATAACA 
AAAACAGATA CCGAAGGTAA AATTAAAGCT AAAGAATATT GTAGAACATT ATTTGCCTAT 
GAAGGTACTA ATGAAGATGA ACTTACTTTT AAAGAGGGGG AGATAATCCA TTTGATAAGT 
AAGGAGACTG GAGAAGCTGG CTGGTGGAGG GGCGAACTTA ATGGTAAAGA AGGAGTATTT 
CCAGACAATT TTGCTGTCCA GATAAATGAA CTTGATAAAG ACTTTCCAAA ACCAAAGAAA 
CCACCACCTC CTGCTAAGGC TCCAGCTCCA AAGCCTGAAC TGATAGCTGC AGAGAAGAAA 
TATTTTTCTT TAAAGCCTGA AGAAAAGGAT GAAAAATCAA CACTGGAACA GAAACCTTCT 
AAACCAGCAG CTCCACAAGT CCCACCCAAG AAACCTACTC CACCTACCAA AGCCAGTAAT 
TTACTGAGAT CTTCTGGAAC AGTGTACCCA AAGCGACCTG AAAAACCAGT TCCTCCACCA 
CCTCCTATAG CCAAGATTAA TGGGGAAGTT TCTAGCATTT CATCAAAATT TGAAACTGAG 
CCAGTATCAA AACTAAAGCT AGATTCTGAA CAGCTGCCCC TTAGACCAAA ATCAGTAGAC 
TTTGATTCAC TTACAGTAAG GACCTCCAAA GAAACAGATT TTGTTTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.
Journal of cell science131(1)(2018 Jan)
Cummins TD,Wu KZL,Bozatzi P,Dingwell KS,Macartney TJ,Wood NT,Varghese J,Gourlay R,Campbell DG,Prescott A,Griffis E,Smith JC,Sapkota GP

Decreased gene expression of CD2AP in Chinese patients with sporadic Alzheimer's disease.
Neurobiology of aging56212.e5-212.e10(2017 Aug)
Tao QQ,Liu ZJ,Sun YM,Li HL,Yang P,Liu DS,Jiang B,Li XY,Xu JF,Wu ZY

Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.
Journal of immunology (Baltimore, Md. : 1950)198(12)4823-4836(2017 Jun)
Schaefer A,van Duijn TJ,Majolee J,Burridge K,Hordijk PL

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CD2AP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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